In vivo 1H MRSI of glycine in brain tumors at 3T

Magnetic Resonance in Medicine

Volumn 75, Issue 1, 2016, Pages 52-62

  Ganji, Sandeep K ^a   Maher, Elizabeth A ^a,b,c   Choi, Changho ^a,b  

^a UNIVERSITY OF TEXAS AT DALLAS   (United States)

^b UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^c UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

Author keywords

3T; 1H MRSI; glycine; human brain, gliomas; PRESS (point resolved spectroscopy)

Indexed keywords

AMINO ACIDS; BRAIN; MAGNETIC RESONANCE SPECTROSCOPY; METABOLITES; MOLAR CONCENTRATION; REGRESSION ANALYSIS;

CONCENTRATION RATIO; HEALTHY VOLUNTEERS; HUMAN BRAIN; LINEAR COMBINATION MODEL; METABOLITE CONCENTRATIONS; MR SPECTROSCOPIC IMAGING; POINT RESOLVED SPECTROSCOPIES; ^1H MRSI;

TUMORS;

CREATINE; GLYCINE; INOSITOL; TUMOR MARKER;

ADULT; AGED; AMINO ACID BLOOD LEVEL; AMINO ACID BRAIN LEVEL; ARTICLE; BRAIN LEVEL; BRAIN REGION; BRAIN TUMOR; CANCER GRADING; CLINICAL ARTICLE; CONTROLLED STUDY; ECHO TIME; FULL WIDTH AT HALF MAXIMUM; GLIOMA; GRAY MATTER; HUMAN; IN VIVO STUDY; METABOLITE BRAIN LEVEL; POINT RESOLVED SPECTROSCOPY; PROTON NUCLEAR MAGNETIC RESONANCE; RADIOFREQUENCY; RADIOLOGICAL PARAMETERS; RELIABILITY; SIGNAL DETECTION; SIGNAL NOISE RATIO; SPECTROSCOPY; VOLUME OF INTEREST; WHITE MATTER; WHOLE BODY SCANNER; ALGORITHM; BRAIN NEOPLASMS; COMPUTER ASSISTED DIAGNOSIS; FEMALE; MALE; METABOLISM; MIDDLE AGED; MOLECULAR IMAGING; NUCLEAR MAGNETIC RESONANCE IMAGING; PATHOLOGY; PROCEDURES; REPRODUCIBILITY; SENSITIVITY AND SPECIFICITY; TISSUE DISTRIBUTION; YOUNG ADULT;

ADULT; AGED; ALGORITHMS; BIOMARKERS, TUMOR; BRAIN NEOPLASMS; FEMALE; HUMANS; IMAGE INTERPRETATION, COMPUTER-ASSISTED; MAGNETIC RESONANCE IMAGING; MALE; MIDDLE AGED; MOLECULAR IMAGING; PROTON MAGNETIC RESONANCE SPECTROSCOPY; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY; TISSUE DISTRIBUTION; YOUNG ADULT;

EID: 84922369637     PISSN: 07403194     EISSN: 15222594     Source Type: Journal    
DOI: 10.1002/mrm.25588     Document Type: Article

References (45)

1. Legendre P,. The glycinergic inhibitory synapse. Cell Mol Life Sci 2001; 58: 760-793.
2. Benarroch EE,. Glycine and its synaptic interactions: functional and clinical implications. Neurology 2011; 77: 677-683.
3. Lamers Y, Williamson J, Theriaque DW, Shuster JJ, Gilbert LR, Keeling C, Stacpoole PW, Gregory JF,. Production of 1-carbon units from glycine is extensive in healthy men and women. J Nutr 2009; 139: 666-671.
4. Eulenburg V, Armsen W, Betz H, Gomeza J,. Glycine transporters: essential regulators of neurotransmission. Trends Biochem Sci 2005; 30: 325-333.
5. Kinoshita Y, Yokota A,. Absolute concentrations of metabolites in human brain tumors using in vitro proton magnetic resonance spectroscopy. NMR Biomed 1997; 10: 2-12.
6. 1H NMR spectroscopic investigation. NMR Biomed 2005; 18: 371-382.
7. 1H MR spectroscopic imaging with short and long echo time to discriminate glycine in glial tumours. MAGMA 2009; 22: 33-41.
8. 1H MRS at 1.5 Tesla confirmed by ex-vivo high-resolution magic-angle spinning NMR. NMR Biomed 2010; 23: 80-87.
9. Righi V, Andronesi OC, Mintzopoulos D, Black PM, Tzika AA,. High-resolution magic angle spinning magnetic resonance spectroscopy detects glycine as a biomarker in brain tumors. Int J Oncol 2010; 36: 301-306.
10. 1H-MRS at 3 T: application in brain tumors. Magn Reson Med 2011; 66: 609-618.
11. 1H MRS at 7.0 T. Magn Reson Med 2012; 68: 325-331.
12. Maudsley AA, Gupta RK, Stoyanova R, Parra NA, Roy B, Sheriff S, Hussain N, Behari S,. Mapping of Glycine Distributions in Gliomas. AJNR Am J Neuroradiol 2014; 35: 31-36.
13. Jain M, Nilsson R, Sharma S, Madhusudhan N, Kitami T, Souza AL, Kafri R, Kirschner MW, Clish CB, Mootha VK,. Metabolite profiling identifies a key role for glycine in rapid cancer cell proliferation. Science 2012; 336: 1040-1044.
14. 1H magnetic resonance spectroscopy. Magn Reson Med 2003; 49: 223-232.
15. 1H MR spectroscopy. NMR Biomed 1994; 7: 172-180.
16. Ott D, Hennig J, Ernst T,. Human brain tumors: assessment with in vivo proton MR spectroscopy. Radiology 1993; 186: 745-752.
17. Govindaraju V, Young K, Maudsley AA,. Proton NMR chemical shifts and coupling constants for brain metabolites. NMR Biomed 2000; 13: 129-153.
18. 1H MRS in human brain at 7 T. MAGMA 2009; 22: 1-4.
19. Prescot AP, de BFB, Wang L, Brown J, Jensen JE, Kaufman MJ, Renshaw PF,. In vivo detection of brain glycine with echo-time-averaged (1)H magnetic resonance spectroscopy at 4.0 T. Magn Reson Med 2006; 55: 681-686.
20. 1H-MRS in vivo at 3.0T. Magn Reson Med 2008; 59: 59-64.
21. Maudsley AA, Matson GB, Hugg JW, Weiner MW,. Reduced phase encoding in spectroscopic imaging. Magn Reson Med 1994; 31: 645-651.
22. 1H NMR spectroscopy. J Magn Reson B 1994; 104: 1-10.
23. Gruetter R,. Automatic, localized in vivo adjustment of all first-and second-order shim coils. Magn Reson Med 1993; 29: 804-811.
24. Naressi A, Couturier C, Devos J, Janssen M, Mangeat C, Beer R, Graveron-Demilly D,. Java-based graphical user interface for the MRUI quantitation package. MAGMA 2001; 12: 141-152.
25. Choi C, Ganji SK, DeBerardinis RJ, et al., 2-hydroxyglutarate detection by magnetic resonance spectroscopy in IDH-mutated patients with gliomas. Nat Med 2012; 18: 624-629.
26. Provencher SW,. Estimation of metabolite concentrations from localized in vivo proton NMR spectra. Magn Reson Med 1993; 30: 672-679.
27. 1H spectra with LCModel. NMR Biomed 2001; 14: 260-264.
28. 2 measurement of J-coupled metabolites in the human brain at 3T. NMR Biomed 2012; 25: 523-529.
29. Ganji SK, An Z, Banerjee A, Madan A, Hulsey KM, Choi C,. Measurement of regional variation of GABA in the human brain by optimized point-resolved spectroscopy at 7 T in vivo. NMR Biomed 2014; 27: 1167-1175.
30. Natt O, Bezkorovaynyy V, Michaelis T, Frahm J,. Use of phased array coils for a determination of absolute metabolite concentrations. Magn Reson Med 2005; 53: 3-8.
31. 1H magnetic resonance spectroscopic imaging. Magn Reson Med 2001; 45: 899-907.
32. Wiebenga OT, Klauser AM, Nagtegaal GJA, Schoonheim MM, Barkhof F, Geurts JJG, Pouwels PJW,. Longitudinal absolute metabolite quantification of white and gray matter regions in healthy controls using proton MR spectroscopic imaging. NMR Biomed 2014; 27: 304-311.
33. 2 metabolite relaxation times in glioma and normal brain at 3T. J Magn Reson Imaging 2008; 28: 342-350.
34. 1H-MRSI of cerebral gray and white matter. Magn Reson Med 2000; 44: 401-411.
35. 1H spectroscopic imaging at 4.1 T. Magn Reson Med 1996; 36: 72-77.
36. Bonekamp D, Smith MA, Zhu H, Barker PB,. Quantitative SENSE-MRSI of the human brain. Magn Reson Imaging 2010; 28: 305-313.
37. Dydak U, Weiger M, Pruessmann KP, Meier D, Boesiger P,. Sensitivity-encoded spectroscopic imaging. Magn Reson Med 2001; 46: 713-722.
38. Posse S, Otazo R, Caprihan A, et al., Proton echo-planar spectroscopic imaging of J-coupled resonances in human brain at 3 and 4 Tesla. Magn Reson Med 2007; 58: 236-244.
39. 1H MR metabolic imaging in the clinic. Radiology 2012; 262: 985-994.
40. Cao P, Wu EX,. Accelerating phase-encoded proton MR spectroscopic imaging by compressed sensing. J Magn Reson Imaging 2015;41: 487-495.
41. Xin L, Gambarota G, Mlynárik V, Gruetter R,. Proton T2 relaxation time of J-coupled cerebral metabolites in rat brain at 9.4 T. NMR Biomed 2008; 21: 396-401.
42. Dreher W, Norris DG, Leibfritz D,. Magnetization transfer affects the proton creatine/phosphocreatine signal intensity: In vivo demonstration in the rat brain. Magn Reson Med 1994; 31: 81-84.
43. Schubert F, Gallinat J, Seifert F, Rinneberg H,. Glutamate concentrations in human brain using single voxel proton magnetic resonance spectroscopy at 3 Tesla. Neuroimage 2004; 21: 1762-1771.
44. Hanahan D, Weinberg Robert A,. Hallmarks of cancer: the next generation. Cell 2011; 144: 646-674.
45. Nikiforov MA, Chandriani S, O'Connell B, Petrenko O, Kotenko I, Beavis A, Sedivy JM, Cole MD,. A functional screen for myc-responsive genes reveals serine hydroxymethyltransferase, a major source of the one-carbon unit for cell metabolism. Mol Cell Biol 2002; 22: 5793-5800.