메뉴 건너뛰기




Volumn 290, Issue 6, 2015, Pages 3814-3824

Neurotrophin Signaling via TrkB and TrkC Receptors Promotes the Growth of Brain Tumor-initiating Cells

Author keywords

[No Author keywords available]

Indexed keywords

BRAIN; CELLS; CHEMICAL ACTIVATION; CYTOLOGY; ENZYME INHIBITION; SIGNALING; TUMORS;

EID: 84922350631     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M114.599373     Document Type: Article
Times cited : (125)

References (39)
  • 1
    • 0037762690 scopus 로고    scopus 로고
    • Neurotrophins and their receptors: A convergence point for many signalling pathways
    • Chao, M. V. (2003) Neurotrophins and their receptors: a convergence point for many signalling pathways. Nat. Rev. Neurosci. 4, 299-309
    • (2003) Nat. Rev. Neurosci. , vol.4 , pp. 299-309
    • Chao, M.V.1
  • 3
    • 65349121788 scopus 로고    scopus 로고
    • Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial
    • Stupp, R., Hegi, M. E., Mason, W. P., van den Bent, M. J., Taphoorn, M. J., and Janzer, R. C. (2009) Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial. Lancet Oncol. 10, 459-466
    • (2009) Lancet Oncol. , vol.10 , pp. 459-466
    • Stupp, R.1    Hegi, M.E.2    Mason, W.P.3    Van Den Bent, M.J.4    Taphoorn, M.J.5    Janzer, R.C.6
  • 6
    • 56849085242 scopus 로고    scopus 로고
    • 7-secretase represents a therapeutic target for the treatment of invasive glioma mediated by the p75 neurotrophin receptor
    • Wang, L., Rahn, J. J., Lun, X., Sun, B., Kelly, J. J., Weiss, S., Robbins, S. M., Forsyth, P. A., and Senger, D. L. (2008) 7-Secretase represents a therapeutic target for the treatment of invasive glioma mediated by the p75 neurotrophin receptor. PLoS Biol. 6, e289
    • (2008) PLoS Biol. , vol.6 , pp. e289
    • Wang, L.1    Rahn, J.J.2    Lun, X.3    Sun, B.4    Kelly, J.J.5    Weiss, S.6    Robbins, S.M.7    Forsyth, P.A.8    Senger, D.L.9
  • 8
    • 0031656850 scopus 로고    scopus 로고
    • Trk A, B, and C are commonly expressed in human astrocytes and astrocytic gliomas but not by human oligodendrocytes and oligodendroglioma
    • Wang, Y., Hagel, C, Hamel, W., Müller, S., Kluwe, L., and Westphal, M. (1998) Trk A, B, and C are commonly expressed in human astrocytes and astrocytic gliomas but not by human oligodendrocytes and oligodendroglioma. Acta Neuropathol. 96, 357-364
    • (1998) Acta Neuropathol. , vol.96 , pp. 357-364
    • Wang, Y.1    Hagel, C.2    Hamel, W.3    Müller, S.4    Kluwe, L.5    Westphal, M.6
  • 9
    • 0037339606 scopus 로고    scopus 로고
    • Expression of the neurotrophin receptors trk A and trk B in adult human astrocytoma and glioblastoma
    • Wadhwa, S., Nag, T. C, Jindal, A., Kushwaha, R., Mahapatra, A. K., and Sarkar, C. (2003) Expression of the neurotrophin receptors Trk A and Trk B in adult human astrocytoma and glioblastoma. J. Biosci. 28, 181-188
    • (2003) J. Biosci. , vol.28 , pp. 181-188
    • Wadhwa, S.1    Nag, T.C.2    Jindal, A.3    Kushwaha, R.4    Mahapatra, A.K.5    Sarkar, C.6
  • 10
    • 38049177045 scopus 로고    scopus 로고
    • Neurotrophin receptors expression and JNK pathway activation in human astrocytomas
    • Assimakopoulou, M., Kondyli, M., Gatzounis, G., Maraziotis, T., and Varakis, J. (2007) Neurotrophin receptors expression and JNK pathway activation in human astrocytomas. BMC Cancer 7, 202
    • (2007) BMC Cancer , vol.7 , pp. 202
    • Assimakopoulou, M.1    Kondyli, M.2    Gatzounis, G.3    Maraziotis, T.4    Varakis, J.5
  • 11
    • 54549108740 scopus 로고    scopus 로고
    • Comprehensive genomic characterization defines human glioblastoma genes and core pathways
    • Cancer Genome Atlas Research Network (2008) Comprehensive genomic characterization defines human glioblastoma genes and core pathways. Nature 455, 1061-1068
    • (2008) Nature , vol.455 , pp. 1061-1068
  • 13
    • 84865203983 scopus 로고    scopus 로고
    • A restricted cell population propagates glioblastoma growth after chemotherapy
    • Chen, J., Li, Y., Yu, T. S., McKay, R. M., Burns, D. K., Kernie, S. G., Parada, L. F. (2012) A restricted cell population propagates glioblastoma growth after chemotherapy. Nature 488, 522-526
    • (2012) Nature , vol.488 , pp. 522-526
    • Chen, J.1    Li, Y.2    Yu, T.S.3    McKay, R.M.4    Burns, D.K.5    Kernie, S.G.6    Parada, L.F.7
  • 15
    • 70349659954 scopus 로고    scopus 로고
    • On trk: The TrkB signal transduction pathway is an increasingly important target in cancer biology
    • Thiele, C. J., Li, Z., and McKee, A. E. (2009) On Trk: the TrkB signal transduction pathway is an increasingly important target in cancer biology. Clin. Cancer Res. 15, 5962-5967
    • (2009) Clin. Cancer Res. , vol.15 , pp. 5962-5967
    • Thiele, C.J.1    Li, Z.2    McKee, A.E.3
  • 17
    • 0035964486 scopus 로고    scopus 로고
    • Trk receptor tyrosine kinases: A bridge between cancer and neural development
    • Nakagawara, A. (2001) Trk receptor tyrosine kinases: a bridge between cancer and neural development. Cancer Lett. 169, 107-114
    • (2001) Cancer Lett. , vol.169 , pp. 107-114
    • Nakagawara, A.1
  • 18
    • 0032698075 scopus 로고    scopus 로고
    • Cell survival promoted by the ras-MAPK signaling pathway by transcription-dependent and -independent mechanisms
    • Bonni, A., Brunet, A., West, A. E., Datta, S. R., Takasu, M. A., and Greenberg, M. E. (1999) Cell survival promoted by the Ras-MAPK signaling pathway by transcription-dependent and -independent mechanisms. Science 286, 1358-1362
    • (1999) Science , vol.286 , pp. 1358-1362
    • Bonni, A.1    Brunet, A.2    West, A.E.3    Datta, S.R.4    Takasu, M.A.5    Greenberg, M.E.6
  • 19
    • 0027966170 scopus 로고
    • Disruption of NGF binding to the low affinity neurotrophin receptor p75LNTR reduces NGF binding to TrkA in PC12 cells
    • Barker, P. A., and Shooter, E. M. (1994) Disruption of NGF binding to the low affinity neurotrophin receptor p75LNTR reduces NGF binding to TrkA in PC12 cells. Neuron 13, 203-215
    • (1994) Neuron , vol.13 , pp. 203-215
    • Barker, P.A.1    Shooter, E.M.2
  • 20
    • 85056068441 scopus 로고    scopus 로고
    • Cellular assays for high-throughput screening for modulators of trk receptor tyrosine kinases
    • Wang, J., Hancock, M.K., Dudek, J. M., and Bi, K.(2008) Cellular assays for high-throughput screening for modulators of Trk receptor tyrosine kinases. Curr. Chem. Genomics 1, 27-33
    • (2008) Curr. Chem. Genomics , vol.1 , pp. 27-33
    • Wang, J.1    Hancock, M.K.2    Dudek, J.M.3    Bi, K.4
  • 27
    • 33747874155 scopus 로고    scopus 로고
    • Notch pathway inhibition depletes stem-like cells and blocks engraftment in embryonal brain tumors
    • Fan, X., Matsui, W., Khaki, L., Stearns, D., Chun, J., Li, Y. M., and Eberhart, C. G. (2006) Notch pathway inhibition depletes stem-like cells and blocks engraftment in embryonal brain tumors. Cancer Res. 66, 7445-7452
    • (2006) Cancer Res. , vol.66 , pp. 7445-7452
    • Fan, X.1    Matsui, W.2    Khaki, L.3    Stearns, D.4    Chun, J.5    Li, Y.M.6    Eberhart, C.G.7
  • 28
    • 70349653550 scopus 로고    scopus 로고
    • Targeted inhibition of the hedgehog pathway in established malignant glioma xenografts enhances survival
    • Sarangi, A., Valadez, J. G., Rush, S., Abel, T. W., Thompson, R. C., and Cooper, M. K. (2009) Targeted inhibition of the Hedgehog pathway in established malignant glioma xenografts enhances survival. Oncogene 28, 3468-3476
    • (2009) Oncogene , vol.28 , pp. 3468-3476
    • Sarangi, A.1    Valadez, J.G.2    Rush, S.3    Abel, T.W.4    Thompson, R.C.5    Cooper, M.K.6
  • 32
    • 55749104726 scopus 로고    scopus 로고
    • Deletion of TrkB in adult progenitors alters newborn neuron integration into hippocampal circuits and increases anxiety-like behavior
    • Bergami, M., Rimondini, R., Santi, S., Blum, R., Götz, M., and Canossa, M. (2008) Deletion of TrkB in adult progenitors alters newborn neuron integration into hippocampal circuits and increases anxiety-like behavior. Proc. Natl. Acad. Sci. U.S.A. 105, 15570-15575
    • (2008) Proc. Natl. Acad. Sci. U.S.A. , vol.105 , pp. 15570-15575
    • Bergami, M.1    Rimondini, R.2    Santi, S.3    Blum, R.4    Götz, M.5    Canossa, M.6
  • 33
  • 34
    • 79955489341 scopus 로고    scopus 로고
    • Identification of a low-molecular weight TrkB antagonist with anxiolytic and antidepressant activity in mice
    • Cazorla, M., Prémont, J., Mann, A., Girard, N., Kellendonk, C., and Rognan, D. (2011) Identification of a low-molecular weight TrkB antagonist with anxiolytic and antidepressant activity in mice. J. Clin. Invest. 121, 1846-1857
    • (2011) J. Clin. Invest. , vol.121 , pp. 1846-1857
    • Cazorla, M.1    Prémont, J.2    Mann, A.3    Girard, N.4    Kellendonk, C.5    Rognan, D.6
  • 36
    • 0033579301 scopus 로고    scopus 로고
    • Mediation by a CREB family transcription factor of NGF-dependent survival of sympathetic neurons
    • Riccio, A., Ahn, S., Davenport, C. M., Blendy, J. A., and Ginty, D. D. (1999) Mediation by a CREB family transcription factor of NGF-dependent survival of sympathetic neurons. Science. 286, 2358-2361
    • (1999) Science , vol.286 , pp. 2358-2361
    • Riccio, A.1    Ahn, S.2    Davenport, C.M.3    Blendy, J.A.4    Ginty, D.D.5
  • 37
    • 0029789643 scopus 로고    scopus 로고
    • Coupling of the RAS-MAPK pathway to gene activation by RSK2, a growth factor-regulated CREB kinase
    • Xing, J., Ginty, D. D., and Greenberg, M. E. (1996) Coupling of the RAS-MAPK pathway to gene activation by RSK2, a growth factor-regulated CREB kinase. Science. 273, 959-963
    • (1996) Science , vol.273 , pp. 959-963
    • Xing, J.1    Ginty, D.D.2    Greenberg, M.E.3
  • 38
    • 0031594573 scopus 로고    scopus 로고
    • Nerve growth factor activates extracellular signal-regulated kinase and p38 mitogen-activated protein kinase pathways to stimulate CREB serine 133 phosphorylation
    • Xing, J., Kornhauser, J. M., Xia, Z., Thiele, E. A., and Greenberg, M. E. (1998) Nerve growth factor activates extracellular signal-regulated kinase and p38 mitogen-activated protein kinase pathways to stimulate CREB serine 133 phosphorylation. Mol. Cell. Biol. 18, 1946-1955
    • (1998) Mol. Cell. Biol. , vol.18 , pp. 1946-1955
    • Xing, J.1    Kornhauser, J.M.2    Xia, Z.3    Thiele, E.A.4    Greenberg, M.E.5
  • 39
    • 0033694754 scopus 로고    scopus 로고
    • The TrkB-shc site signals neuronal survival and local axon growth via MEK and P13-kinase
    • Atwal, J. K., Massie, B., Miller, F. D., and Kaplan, D. R. (2000) The TrkB-Shc site signals neuronal survival and local axon growth via MEK and P13-kinase. Neuron. 27, 265-277
    • (2000) Neuron. , vol.27 , pp. 265-277
    • Atwal, J.K.1    Massie, B.2    Miller, F.D.3    Kaplan, D.R.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.