The guanine nucleotide exchange factor Ric-8a induces domain separation and Ras domain plasticity in Gαi1

Proceedings of the National Academy of Sciences of the United States of America

Volumn 112, Issue 5, 2015, Pages 1404-1409

  Van Eps, Ned ^a   Thomas, Celestine J ^b   Hubbell, Wayne L ^a   Sprang, Stephen R ^b  

^a JULES STEIN EYE INSTITUTE   (United States)

^b UNIVERSITY OF MONTANA   (United States)

Author keywords

Double electron electron resonance spectroscopy; G protein; Guanine nucleotide exchange factor; Protein dynamics; Tertiary structure

Indexed keywords

BETA 2 ADRENERGIC RECEPTOR; G ALPHA I1 PROTEIN; GUANINE NUCLEOTIDE BINDING PROTEIN ALPHA SUBUNIT; GUANINE NUCLEOTIDE EXCHANGE FACTOR; GUANINE NUCLEOTIDE EXCHANGE FACTOR RIC 8A; GUANOSINE 5' O (3 THIOTRIPHOSPHATE); RAS PROTEIN; UNCLASSIFIED DRUG;

ARTICLE; COMPLEX FORMATION; DOUBLE ELECTRON ELECTRON RESONANCE SPECTROSCOPY; ELECTRON SPIN RESONANCE; NUCLEOTIDE BINDING SITE; PLASTICITY; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN DOMAIN; PROTEIN STRUCTURE; SPECTROSCOPY; SPIN LABELING; ANIMAL; BOVINE; CHEMICAL STRUCTURE; CHEMISTRY; GENETICS; METABOLISM; PHYSIOLOGY; PROCEDURES;

ANIMALS; CATTLE; ELECTRON SPIN RESONANCE SPECTROSCOPY; GTP-BINDING PROTEIN ALPHA SUBUNITS; GUANINE NUCLEOTIDE EXCHANGE FACTORS; MODELS, MOLECULAR; RAS PROTEINS;

EID: 84922324312     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1423878112     Document Type: Article

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