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Volumn 466, Issue , 2015, Pages 163-176

Decreased adipogenesis and adipose tissue in mice with inactivated protein phosphatase 5

Author keywords

Glucocorticoid receptor; Hsp90; PP5; PPAR ; Preadipocyte differentiation; Preadipocyte factor 1

Indexed keywords

DELTA LIKE PROTEIN 1; GLUCOCORTICOID; GLUCOCORTICOID RECEPTOR; MITOGEN ACTIVATED PROTEIN KINASE 1; PHOSPHOPROTEIN PHOSPHATASE; PREADIPOCYTE FACTOR 1; PROTEIN; PROTEIN PHOSPHATASE 5; TRANSCRIPTION FACTOR SOX9; UNCLASSIFIED DRUG; CCAAT ENHANCER BINDING PROTEIN; CCAAT ENHANCER BINDING PROTEIN BETA; CEBPA PROTEIN, MOUSE; CEBPB PROTEIN, MOUSE; DEXAMETHASONE; DLL3 PROTEIN, MOUSE; HEAT SHOCK PROTEIN 90; MEMBRANE PROTEIN; NUCLEAR PROTEIN; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; SIGNAL PEPTIDE; SOX9 PROTEIN, MOUSE;

EID: 84922291710     PISSN: 02646021     EISSN: 14708728     Source Type: Journal    
DOI: 10.1042/BJ20140428     Document Type: Article
Times cited : (11)

References (50)
  • 1
    • 0030925683 scopus 로고    scopus 로고
    • Steroid receptor interactions with heat shock protein and immunophilin chaperones
    • PubMed
    • Pratt, W.B. and Toft, D.O. (1997) Steroid receptor interactions with heat shock protein and immunophilin chaperones. Endocr. Rev. 18, 306-360 PubMed
    • (1997) Endocr. Rev. , vol.18 , pp. 306-360
    • Pratt, W.B.1    Toft, D.O.2
  • 2
    • 0028133445 scopus 로고
    • A novel human protein serine/threonine phosphatase which possesses four tetratricopeptide repeat motifs and localizes to the nucleus
    • PubMed
    • Chen, M.X., McPartlin, A.E., Brown, L., Chen, Y.H., Barker, H.M. and Cohen, P. T. W. (1994) A novel human protein serine/threonine phosphatase which possesses four tetratricopeptide repeat motifs and localizes to the nucleus. EMBO J. 13, 4278-4290 PubMed
    • (1994) EMBO J. , vol.13 , pp. 4278-4290
    • Chen, M.X.1    McPartlin, A.E.2    Brown, L.3    Chen, Y.H.4    Barker, H.M.5    Cohen, P.T.W.6
  • 3
    • 0028117770 scopus 로고
    • Targeting of a distinctive protein-serine phosphatase to the protein kinase- like domain of the atrial natriuretic peptide receptor
    • CrossRef PubMed
    • Chinkers, M. (1994) Targeting of a distinctive protein-serine phosphatase to the protein kinase- like domain of the atrial natriuretic peptide receptor. Proc. Natl. Acad. Sci. U.S.A. 91, 11075-11079 CrossRef PubMed
    • (1994) Proc. Natl. Acad. Sci. U.S.A. , vol.91 , pp. 11075-11079
    • Chinkers, M.1
  • 4
    • 0029751136 scopus 로고    scopus 로고
    • The tetratricopeptide repeat domain of protein phosphatase 5 mediates binding to glucocorticoid receptor heterocomplexes and acts as a dominant negative mutant
    • CrossRef PubMed
    • Chen, M.-S., Silverstein, A.M., Pratt, W.B. and Chinkers, M. (1996) The tetratricopeptide repeat domain of protein phosphatase 5 mediates binding to glucocorticoid receptor heterocomplexes and acts as a dominant negative mutant. J. Biol. Chem. 271, 32315-32320 CrossRef PubMed
    • (1996) J. Biol. Chem. , vol.271 , pp. 32315-32320
    • Chen, M.-S.1    Silverstein, A.M.2    Pratt, W.B.3    Chinkers, M.4
  • 5
    • 0030921056 scopus 로고    scopus 로고
    • Protein phosphatase 5 is a major component of glucocorticoid receptor-hsp90 complexes with properties of an FK506-binding immunophilin
    • CrossRef PubMed
    • Silverstein, A.M., Galigniana, M.D., Chen, M.-S., Owens-Grillo, J.K., Chinkers, M. and Pratt, W.B. (1997) Protein phosphatase 5 is a major component of glucocorticoid receptor-hsp90 complexes with properties of an FK506-binding immunophilin. J. Biol. Chem. 272, 16224-16230 CrossRef PubMed
    • (1997) J. Biol. Chem. , vol.272 , pp. 16224-16230
    • Silverstein, A.M.1    Galigniana, M.D.2    Chen, M.-S.3    Owens-Grillo, J.K.4    Chinkers, M.5    Pratt, W.B.6
  • 6
    • 0035234311 scopus 로고    scopus 로고
    • Protein phosphatase 5 in signal transduction
    • CrossRef PubMed
    • Chinkers, M. (2001) Protein phosphatase 5 in signal transduction. Trends Endocrinol. Metab. 12, 28-32 CrossRef PubMed
    • (2001) Trends Endocrinol. Metab. , vol.12 , pp. 28-32
    • Chinkers, M.1
  • 7
    • 12744273395 scopus 로고    scopus 로고
    • Human protein phosphatase 5 dissociates from heat-shock proteins and is proteolytically activated in response to arachidonic acid and the microtubule-depolymerizing drug nocodazole
    • CrossRef PubMed
    • Zeke, T., Morrice, N., V ázquez-Martin, C. and Cohen, P. T. W. (2005) Human protein phosphatase 5 dissociates from heat-shock proteins and is proteolytically activated in response to arachidonic acid and the microtubule-depolymerizing drug nocodazole. Biochem. J. 385, 45-56 CrossRef PubMed
    • (2005) Biochem. J. , vol.385 , pp. 45-56
    • Zeke, T.1    Morrice, N.2    Vázquez-Martin, C.3    Cohen, P.T.W.4
  • 9
    • 52949129878 scopus 로고    scopus 로고
    • Control of glucocorticoid and progesterone receptor subcellular localization by the ligand-binding domain is mediated by distinct interactions with tetratricopeptide repeat proteins
    • CrossRef PubMed
    • Banerjee, A., Periyasamy, S., Wolf, I.M., Hinds, T.D., Jr., Yong, W., Shou, W. and Sanchez, E.R. (2008) Control of glucocorticoid and progesterone receptor subcellular localization by the ligand-binding domain is mediated by distinct interactions with tetratricopeptide repeat proteins. Biochemistry 47, 10471-10480 CrossRef PubMed
    • (2008) Biochemistry , vol.47 , pp. 10471-10480
    • Banerjee, A.1    Periyasamy, S.2    Wolf, I.M.3    Hinds, T.D.4    Yong, W.5    Shou, W.6    Sanchez, E.R.7
  • 11
    • 13244253758 scopus 로고    scopus 로고
    • Molecular basis for TPR domain-mediated regulation of protein phosphatase 5
    • CrossRef PubMed
    • Yang, J., Roe, S.M., Cliff, M.J., Williams, M.J., Ladbury, M.A., Cohen, P. T. W. and Barford, D. (2005) Molecular basis for TPR domain-mediated regulation of protein phosphatase 5. EMBO J. 24, 1-10 CrossRef PubMed
    • (2005) EMBO J. , vol.24 , pp. 1-10
    • Yang, J.1    Roe, S.M.2    Cliff, M.J.3    Williams, M.J.4    Ladbury, M.A.5    Cohen, P.T.W.6    Barford, D.7
  • 12
    • 0031015069 scopus 로고    scopus 로고
    • Activation of protein phosphatase 5 by limited proteolysis or the binding of fatty acids to the TPR domain
    • CrossRef PubMed
    • Chen, M.X. and Cohen, P. T. W. (1997) Activation of protein phosphatase 5 by limited proteolysis or the binding of fatty acids to the TPR domain. FEBS Lett. 400, 136-140 CrossRef PubMed
    • (1997) FEBS Lett. , vol.400 , pp. 136-140
    • Chen, M.X.1    Cohen, P.T.W.2
  • 13
    • 0030928118 scopus 로고    scopus 로고
    • Purification of a fatty acid-stimulated protein-serine/threonine phosphatase from bovine brain and its identification as a homolog of protein phosphatase 5
    • CrossRef PubMed
    • Skinner, J., Sinclair, C., Romeo, C., Armstrong, D., Charbonneau, H. and Rossie, S. (1997) Purification of a fatty acid-stimulated protein-serine/threonine phosphatase from bovine brain and its identification as a homolog of protein phosphatase 5. J. Biol. Chem. 272, 22464-22471 CrossRef PubMed
    • (1997) J. Biol. Chem. , vol.272 , pp. 22464-22471
    • Skinner, J.1    Sinclair, C.2    Romeo, C.3    Armstrong, D.4    Charbonneau, H.5    Rossie, S.6
  • 14
    • 0037197702 scopus 로고    scopus 로고
    • Identification of potential physiological activators of protein phosphatase 5
    • CrossRef PubMed
    • Ramsey, A.J. and Chinkers, M. (2002) Identification of potential physiological activators of protein phosphatase 5. Biochemistry 41, 5625-5632 CrossRef PubMed
    • (2002) Biochemistry , vol.41 , pp. 5625-5632
    • Ramsey, A.J.1    Chinkers, M.2
  • 15
    • 0040370216 scopus 로고    scopus 로고
    • Ser/Thr protein phosphatase type 5 (PP5) is a negative regulator of glucocorticoid receptor-mediated growth arrest
    • CrossRef PubMed
    • Zuo, Z., Urban, G., Scammell, J.G., Dean, N.M., McLean, T.K., Aragon, I. and Honkanen, R.E. (1999) Ser/Thr protein phosphatase type 5 (PP5) is a negative regulator of glucocorticoid receptor-mediated growth arrest. Biochemistry 38, 8849-8857 CrossRef PubMed
    • (1999) Biochemistry , vol.38 , pp. 8849-8857
    • Zuo, Z.1    Urban, G.2    Scammell, J.G.3    Dean, N.M.4    McLean, T.K.5    Aragon, I.6    Honkanen, R.E.7
  • 16
    • 33847198615 scopus 로고    scopus 로고
    • Modulation of glucocorticoid receptor phosphorylation and transcriptional activity by a C-terminal-associated protein phosphatase
    • CrossRef PubMed
    • Wang, Z., Chen, W., Kono, E., Dang, T. and Garabedian, M.J. (2007) Modulation of glucocorticoid receptor phosphorylation and transcriptional activity by a C-terminal-associated protein phosphatase. Mol. Endocrinol. 21, 625-634CrossRef PubMed
    • (2007) Mol. Endocrinol , vol.21 , pp. 625-634
    • Wang, Z.1    Chen, W.2    Kono, E.3    Dang, T.4    Garabedian, M.J.5
  • 17
    • 34447525646 scopus 로고    scopus 로고
    • Mice lacking protein phosphatase 5 are defective in ataxia telangiectasia mutated (ATM)-mediated cell cycle arrest
    • CrossRef PubMed
    • Yong, W., Bao, S., Chen, H., Li, D., Sanchez, E.R. and Shou, W. (2007) Mice lacking protein phosphatase 5 are defective in ataxia telangiectasia mutated (ATM)-mediated cell cycle arrest. J. Biol. Chem. 282, 14690-14694 CrossRef PubMed
    • (2007) J. Biol. Chem. , vol.282 , pp. 14690-14694
    • Yong, W.1    Bao, S.2    Chen, H.3    Li, D.4    Sanchez, E.R.5    Shou, W.6
  • 18
    • 81755172405 scopus 로고    scopus 로고
    • Disruption of serine/threonine protein phosphatase 5 (PP5:PPP5 c) in mice reveals a novel role for PP5 in the regulation of ultraviolet light-induced phosphorylation of serine/threonine protein kinase Chk1 (CHEK1)
    • CrossRef PubMed
    • Amable, L., Grankvist, N., Largen, J.W., Ortsater, H., Sjoholm, A. and Honkanen, R.E. (2011) Disruption of serine/threonine protein phosphatase 5 (PP5:PPP5 c) in mice reveals a novel role for PP5 in the regulation of ultraviolet light-induced phosphorylation of serine/threonine protein kinase Chk1 (CHEK1). J. Biol. Chem. 286, 40413-40422CrossRef PubMed
    • (2011) J. Biol. Chem , vol.286 , pp. 40413-40422
    • Amable, L.1    Grankvist, N.2    Largen, J.W.3    Ortsater, H.4    Sjoholm, A.5    Honkanen, R.E.6
  • 19
    • 79953304737 scopus 로고    scopus 로고
    • Novel pathway of adipogenesis through cross-talk between adipose tissue macrophages, adipose stem cells and adipocytes: Evidence of cell plasticity
    • CrossRef PubMed
    • Chazenbalk, G., Bertolotto, C., Heneidi, S., Jumabay, M., Trivax, B., Aronowitz, J., Yoshimura, K., Simmons, C.F., Dumesic, D.A. and Azziz, R. (2011) Novel pathway of adipogenesis through cross-talk between adipose tissue macrophages, adipose stem cells and adipocytes: evidence of cell plasticity. PLoS One 6, e17834 CrossRef PubMed
    • (2011) PLoS One , vol.6 , pp. e17834
    • Chazenbalk, G.1    Bertolotto, C.2    Heneidi, S.3    Jumabay, M.4    Trivax, B.5    Aronowitz, J.6    Yoshimura, K.7    Simmons, C.F.8    Dumesic, D.A.9    Azziz, R.10
  • 20
    • 0030977268 scopus 로고    scopus 로고
    • Structural basis for the recognition of regulatory subunits by the catalytic subunit of protein phosphatase 1
    • CrossRef PubMed
    • Egloff, M.-P., Johnson, F., Moorhead, G., Cohen, P. T. W., Cohen, P. and Barford, D. (1997) Structural basis for the recognition of regulatory subunits by the catalytic subunit of protein phosphatase 1. EMBO J. 16, 1876-1887 CrossRef PubMed
    • (1997) EMBO J. , vol.16 , pp. 1876-1887
    • Egloff, M.-P.1    Johnson, F.2    Moorhead, G.3    Cohen, P.T.W.4    Cohen, P.5    Barford, D.6
  • 22
    • 0031898610 scopus 로고    scopus 로고
    • PPAR-gamma: Adipogenic regulator and thiazolidinedione receptor
    • CrossRef PubMed
    • Spiegelman, B.M. (1998) PPAR-gamma: adipogenic regulator and thiazolidinedione receptor. Diabetes 47, 507-514 CrossRef PubMed
    • (1998) Diabetes , vol.47 , pp. 507-514
    • Spiegelman, B.M.1
  • 23
    • 83355166922 scopus 로고    scopus 로고
    • Protein phosphatase 5 mediates lipid metabolism through reciprocal control of glucocorticoid receptor and peroxisome proliferator-activated receptor-gamma (PPARgamma)
    • CrossRef PubMed
    • Hinds, T.D. Jr., Stechschulte, L.A., Cash, H.A., Whisler, D., Banerjee, A., Yong, W., Khuder, S.S., Kaw, M.K., Shou, W., Najjar, S.M. and Sanchez, E.R. (2011) Protein phosphatase 5 mediates lipid metabolism through reciprocal control of glucocorticoid receptor and peroxisome proliferator-activated receptor-gamma (PPARgamma). J. Biol. Chem. 286, 42911-42922 CrossRef PubMed
    • (2011) J. Biol. Chem. , vol.286 , pp. 42911-42922
    • Hinds, T.D.1    Stechschulte, L.A.2    Cash, H.A.3    Whisler, D.4    Banerjee, A.5    Yong, W.6    Khuder, S.S.7    Kaw, M.K.8    Shou, W.9    Najjar, S.M.10    Sanchez, E.R.11
  • 24
    • 0032742092 scopus 로고    scopus 로고
    • Glucocorticoid receptor inhibits transforming growth factor-beta signaling by directly targeting the transcriptional activation function of Smad3
    • CrossRef PubMed
    • Song, C.Z., Tian, X. and Gelehrter, T.D. (1999) Glucocorticoid receptor inhibits transforming growth factor-beta signaling by directly targeting the transcriptional activation function of Smad3. Proc. Natl. Acad. Sci. U.S.A. 96, 11776-11781 CrossRef PubMed
    • (1999) Proc. Natl. Acad. Sci. U.S.A. , vol.96 , pp. 11776-11781
    • Song, C.Z.1    Tian, X.2    Gelehrter, T.D.3
  • 25
    • 0033617150 scopus 로고    scopus 로고
    • Transcriptional repression of pref-1 by glucocorticoids promotes 3T3-L1 adipocyte differentiation
    • CrossRef PubMed
    • Smas, C.M., Chen, L., Zhao, L., Latasa, M.J. and Sul, H.S. (1999) Transcriptional repression of pref-1 by glucocorticoids promotes 3T3-L1 adipocyte differentiation. J. Biol. Chem. 274, 12632-12641 CrossRef PubMed
    • (1999) J. Biol. Chem. , vol.274 , pp. 12632-12641
    • Smas, C.M.1    Chen, L.2    Zhao, L.3    Latasa, M.J.4    Sul, H.S.5
  • 26
    • 33751200644 scopus 로고    scopus 로고
    • Modulation of early human preadipocyte differentiation by glucocorticoids
    • CrossRef PubMed
    • Tomlinson, J.J., Boudreau, A., Wu, D., Atlas, E. and Hache, R.J. (2006) Modulation of early human preadipocyte differentiation by glucocorticoids. Endocrinology 147, 5284-5293 CrossRef PubMed
    • (2006) Endocrinology , vol.147 , pp. 5284-5293
    • Tomlinson, J.J.1    Boudreau, A.2    Wu, D.3    Atlas, E.4    Hache, R.J.5
  • 27
    • 33947248112 scopus 로고    scopus 로고
    • Pref-1 (preadipocyte factor 1) activates the MEK/extracellular signal-regulated kinase pathway to inhibit adipocyte differentiation
    • CrossRef PubMed
    • Kim, K.A., Kim, J.H., Wang, Y. and Sul, H.S. (2007) Pref-1 (preadipocyte factor 1) activates the MEK/extracellular signal-regulated kinase pathway to inhibit adipocyte differentiation. Mol. Cell. Biol. 27, 2294-2308 CrossRef PubMed
    • (2007) Mol. Cell. Biol. , vol.27 , pp. 2294-2308
    • Kim, K.A.1    Kim, J.H.2    Wang, Y.3    Sul, H.S.4
  • 28
    • 60649109364 scopus 로고    scopus 로고
    • Pref-1 regulates mesenchymal cell commitment and differentiation through Sox9
    • CrossRef PubMed
    • Wang, Y. and Sul, H.S. (2009) Pref-1 regulates mesenchymal cell commitment and differentiation through Sox9. Cell Metab. 9, 287-302 CrossRef PubMed
    • (2009) Cell Metab. , vol.9 , pp. 287-302
    • Wang, Y.1    Sul, H.S.2
  • 29
    • 0028878375 scopus 로고
    • Cascade regulation of terminal adipocyte differentiation by three members of the C/EBP family of leucine zipper proteins
    • CrossRef PubMed
    • Yeh, W.C., Cao, Z., Classon, M. and McKnight, S.L. (1995) Cascade regulation of terminal adipocyte differentiation by three members of the C/EBP family of leucine zipper proteins. Genes Dev. 9, 168-181 CrossRef PubMed
    • (1995) Genes Dev. , vol.9 , pp. 168-181
    • Yeh, W.C.1    Cao, Z.2    Classon, M.3    McKnight, S.L.4
  • 30
    • 33748942837 scopus 로고    scopus 로고
    • Transcriptional control of adipocyte formation
    • CrossRef PubMed
    • Farmer, S.R. (2006) Transcriptional control of adipocyte formation. Cell Metab. 4, 263-273 CrossRef PubMed
    • (2006) Cell Metab. , vol.4 , pp. 263-273
    • Farmer, S.R.1
  • 31
    • 0034713765 scopus 로고    scopus 로고
    • Glucocorticoids inhibit the transcriptional response of the uncoupling protein-1 gene to adrenergic stimulation in a brown adipose cell line
    • CrossRef PubMed
    • Soumano, K., Desbiens, S., Rabelo, R., Bakopanos, E., Camirand, A. and Silva, J.E. (2000) Glucocorticoids inhibit the transcriptional response of the uncoupling protein-1 gene to adrenergic stimulation in a brown adipose cell line. Mol. Cell. Endocrinol. 165, 7-15 CrossRef PubMed
    • (2000) Mol. Cell. Endocrinol. , vol.165 , pp. 7-15
    • Soumano, K.1    Desbiens, S.2    Rabelo, R.3    Bakopanos, E.4    Camirand, A.5    Silva, J.E.6
  • 32
    • 0029088326 scopus 로고
    • Targeted disruption of the glucocorticoid receptor gene blocks adrenergic chromaffin cell development and severely retards lung maturation
    • CrossRef PubMed
    • Cole, T.J., Blendy, J.A., Monaghan, A.P., Krieglstein, K., Schmid, W., Aguzzi, A., Fantuzzi, G., Hummler, E., Unsicker, K. and Schutz, G. (1995) Targeted disruption of the glucocorticoid receptor gene blocks adrenergic chromaffin cell development and severely retards lung maturation. Genes Dev. 9, 1608-1621 CrossRef PubMed
    • (1995) Genes Dev. , vol.9 , pp. 1608-1621
    • Cole, T.J.1    Blendy, J.A.2    Monaghan, A.P.3    Krieglstein, K.4    Schmid, W.5    Aguzzi, A.6    Fantuzzi, G.7    Hummler, E.8    Unsicker, K.9    Schutz, G.10
  • 33
    • 0029093343 scopus 로고
    • Role of acidic and phosphorylated residues in gene activation by the glucocorticoid receptor
    • CrossRef PubMed
    • Almlof, T., Wright, A.P. and Gustafsson, J.A. (1995) Role of acidic and phosphorylated residues in gene activation by the glucocorticoid receptor. J. Biol. Chem. 270, 17535-17540 CrossRef PubMed
    • (1995) J. Biol. Chem. , vol.270 , pp. 17535-17540
    • Almlof, T.1    Wright, A.P.2    Gustafsson, J.A.3
  • 34
    • 0030900729 scopus 로고    scopus 로고
    • Mouse glucocorticoid receptor phosphorylation status influences multiple functions of the receptor protein
    • CrossRef PubMed
    • Webster, J.C., Jewell, C.M., Bodwell, J.E., Munck, A., Sar, M. and Cidlowski, J.A. (1997) Mouse glucocorticoid receptor phosphorylation status influences multiple functions of the receptor protein. J. Biol. Chem. 272, 9287-9293 CrossRef PubMed
    • (1997) J. Biol. Chem. , vol.272 , pp. 9287-9293
    • Webster, J.C.1    Jewell, C.M.2    Bodwell, J.E.3    Munck, A.4    Sar, M.5    Cidlowski, J.A.6
  • 35
    • 84857042430 scopus 로고    scopus 로고
    • Chaperoning steroidal physiology: Lessons from mouse genetic models of Hsp90 and its cochaperones
    • CrossRef PubMed
    • Sanchez, E.R. (2012) Chaperoning steroidal physiology: Lessons from mouse genetic models of Hsp90 and its cochaperones. Biochim. Biophys. Acta 1823, 722-729 CrossRef PubMed
    • (2012) Biochim. Biophys. Acta , vol.1823 , pp. 722-729
    • Sanchez, E.R.1
  • 37
    • 58649095526 scopus 로고    scopus 로고
    • Novel insights into glucocorticoid-mediated diabetogenic effects: Towards expansion of therapeutic options?
    • CrossRef PubMed
    • van Raalte, D.H., Ouwens, D.M. and Diamant, M. (2009) Novel insights into glucocorticoid-mediated diabetogenic effects: towards expansion of therapeutic options? Eur. J. Clin. Invest. 39, 81-93 CrossRef PubMed
    • (2009) Eur. J. Clin. Invest. , vol.39 , pp. 81-93
    • Van Raalte, D.H.1    Ouwens, D.M.2    Diamant, M.3
  • 38
    • 0043025533 scopus 로고    scopus 로고
    • Adiponectin: More than just another fat cell hormone?
    • CrossRef PubMed
    • Chandran, M., Phillips, S.A., Ciaraldi, T. and Henry, R.R. (2003) Adiponectin: more than just another fat cell hormone? Diabetes Care 26, 2442-2450 CrossRef PubMed
    • (2003) Diabetes Care , vol.26 , pp. 2442-2450
    • Chandran, M.1    Phillips, S.A.2    Ciaraldi, T.3    Henry, R.R.4
  • 40
    • 84859157750 scopus 로고    scopus 로고
    • Fatty acid transport proteins, implications in physiology and disease
    • CrossRef PubMed
    • Kazantzis, M. and Stahl, A. (2012) Fatty acid transport proteins, implications in physiology and disease. Biochim. Biophys. Acta 1821, 852-857 CrossRef PubMed
    • (2012) Biochim. Biophys. Acta , vol.1821 , pp. 852-857
    • Kazantzis, M.1    Stahl, A.2
  • 43
    • 0038322020 scopus 로고    scopus 로고
    • Transforming growth factor-beta inhibits adipocyte differentiation by Smad3 interacting with CCAAT/enhancer-binding protein (C/EBP) and repressing C/EBP transactivation function
    • CrossRef PubMed
    • Choy, L. and Derynck, R. (2003) Transforming growth factor-beta inhibits adipocyte differentiation by Smad3 interacting with CCAAT/enhancer-binding protein (C/EBP) and repressing C/EBP transactivation function. J. Biol. Chem. 278, 9609-9619 CrossRef PubMed
    • (2003) J. Biol. Chem. , vol.278 , pp. 9609-9619
    • Choy, L.1    Derynck, R.2
  • 44
    • 33845325476 scopus 로고    scopus 로고
    • Adipocyte differentiation from the inside out
    • CrossRef PubMed
    • Rosen, E.D. and MacDougald, O.A. (2006) Adipocyte differentiation from the inside out. Nat. Rev. Mol. Cell Biol. 7, 885-896 CrossRef PubMed
    • (2006) Nat. Rev. Mol. Cell Biol. , vol.7 , pp. 885-896
    • Rosen, E.D.1    MacDougald, O.A.2
  • 45
    • 34547872322 scopus 로고    scopus 로고
    • The glucocorticoid responses are shaped by molecular chaperones
    • CrossRef PubMed
    • Grad, I. and Picard, D. (2007) The glucocorticoid responses are shaped by molecular chaperones. Mol. Cell. Endocrinol. 275, 2-12 CrossRef PubMed
    • (2007) Mol. Cell. Endocrinol. , vol.275 , pp. 2-12
    • Grad, I.1    Picard, D.2
  • 48
    • 84865628717 scopus 로고    scopus 로고
    • Serine/threonine protein phosphatase 5 regulates glucose homeostasis in vivo and apoptosis signalling in mouse pancreatic islets and clonal MIN6 cells
    • CrossRef PubMed
    • Grankvist, N., Amable, L., Honkanen, R.E., Sjoholm, A. and Ortsater, H. (2012) Serine/threonine protein phosphatase 5 regulates glucose homeostasis in vivo and apoptosis signalling in mouse pancreatic islets and clonal MIN6 cells. Diabetologia 55, 2005-2015 CrossRef PubMed
    • (2012) Diabetologia , vol.55 , pp. 2005-2015
    • Grankvist, N.1    Amable, L.2    Honkanen, R.E.3    Sjoholm, A.4    Ortsater, H.5
  • 49
    • 84887903824 scopus 로고    scopus 로고
    • Genetic disruption of protein phosphatase 5 in mice prevents high-fat diet feeding-induced weight gain
    • CrossRef PubMed
    • Grankvist, N., Honkanen, R.E., Sjoholm, A. and Ortsater, H. (2013) Genetic disruption of protein phosphatase 5 in mice prevents high-fat diet feeding-induced weight gain. FEBS Lett. 587, 3869-3874 CrossRef PubMed
    • (2013) FEBS Lett. , vol.587 , pp. 3869-3874
    • Grankvist, N.1    Honkanen, R.E.2    Sjoholm, A.3    Ortsater, H.4
  • 50
    • 84879868603 scopus 로고    scopus 로고
    • Metabolic pitfalls of CNS Cre-based technology
    • CrossRef PubMed
    • Harno, E., Cottrell, E.C. and White, A. (2013) Metabolic pitfalls of CNS Cre-based technology. Cell Metab. 18, 21-28 CrossRef PubMed
    • (2013) Cell Metab. , vol.18 , pp. 21-28
    • Harno, E.1    Cottrell, E.C.2    White, A.3


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