Serine/threonine protein phosphatase 5 regulates glucose homeostasis in vivo and apoptosis signalling in mouse Pancreatic islets and clonal MIN6 cells

Diabetologia

Volumn 55, Issue 7, 2012, Pages 2005-2015

  Grankvist, N ^a   Amable, L ^b   Honkanen, R E ^b   Sjoholm A ^a   Ortsater H ^a  

^a KAROLINSKA INSTITUTE   (Sweden)

^b UNIVERSITY OF SOUTH ALABAMA   (United States)

Author keywords

Apoptosis; Diabetes; Oxidative stress; Pancreatic islet; Protein phosphatase 5

Indexed keywords

C PEPTIDE; GLUCOSE; HYDROGEN PEROXIDE; INSULIN; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE; PALMITIC ACID; PHOSPHOPROTEIN PHOSPHATASE; PHOSPHOPROTEIN PHOSPHATASE 2A; PROTEIN C JUN; SERINE THREONINE PROTEIN PHOSPHATASE 5; SHORT HAIRPIN RNA; STRESS ACTIVATED PROTEIN KINASE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BODY WEIGHT; CELL VIABILITY; CONTROLLED STUDY; DIET RESTRICTION; ENZYME ACTIVITY; ENZYME LINKED IMMUNOSORBENT ASSAY; ENZYME PHOSPHORYLATION; GENE EXPRESSION; GLUCOSE BLOOD LEVEL; GLUCOSE HOMEOSTASIS; GLUCOSE TOLERANCE TEST; IMPAIRED GLUCOSE TOLERANCE; IN VITRO STUDY; IN VIVO STUDY; INSULIN RELEASE; INSULIN SENSITIVITY; INSULIN TOLERANCE TEST; MALE; MOUSE; NONHUMAN; PANCREAS ISLET; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; WESTERN BLOTTING;

ANIMALS; APOPTOSIS; BASE SEQUENCE; DIABETES MELLITUS, EXPERIMENTAL; DIABETES MELLITUS, TYPE 2; GLUCOSE TOLERANCE TEST; HOMEOSTASIS; ISLETS OF LANGERHANS; JNK MITOGEN-ACTIVATED PROTEIN KINASES; MALE; MICE; MITOGEN-ACTIVATED PROTEIN KINASES; NUCLEAR PROTEINS; PHOSPHOPROTEIN PHOSPHATASES; REACTIVE OXYGEN SPECIES; SIGNAL TRANSDUCTION;

EID: 84865628717     PISSN: 0012186X     EISSN: 14320428     Source Type: Journal    
DOI: 10.1007/s00125-012-2541-1     Document Type: Article

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