Choline kinase β mutant mice exhibit reduced phosphocholine, elevated osteoclast activity, and low bone mass

Journal of Biological Chemistry

Volumn 290, Issue 3, 2015, Pages 1729-1742

  Kular, Jasreen ^a   Tickner, Jennifer C ^a   Pavlos, Nathan J ^a   Viola, Helena M ^a   Abel, Tamara ^a   Lim, Bay Sie ^a   Yang, Xiaohong ^b   Chen, Honghui ^b   Cook, Robert ^a   Hool, Livia C ^a   Zheng, Ming Hao ^a   Xu, Jiake ^a  

^a UNIVERSITY OF WESTERN AUSTRALIA   (Australia)

^b MEDICAL COLLEGE OF JINAN UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

BIOCHEMISTRY; ENZYMES; MAMMALS; PHYSIOLOGY;

BONE HOMEOSTASIS; MOLECULAR MECHANISM; OSTEOCLAST ACTIVITY; OSTEOCLAST FORMATION; PHOSPHATIDYLCHOLINE; PHYSIOLOGICAL LEVELS; REDUCED SENSITIVITY; SPECIALIZED CELLS;

BONE;

ADENOSINE TRIPHOSPHATASE; ADENOSINE TRIPHOSPHATASE SUBUNIT D2; CALCIUM; CATHEPSIN K; CHOLINE KINASE; CHOLINE KINASE BETA; CITICOLINE; GLYCEROPHOSPHORYLCHOLINE; MITOGEN ACTIVATED PROTEIN KINASE; PHOSPHATIDYLCHOLINE; PHOSPHORYLCHOLINE; SYNAPTOPHYSIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BONE DENSITY; BONE HOMEOSTASIS; BONE MASS; BONE MINERALIZATION; CALCIUM TRANSPORT; CELL COUNT; CELL FUNCTION; CELL PROLIFERATION; CONTROLLED STUDY; ENZYME ACTIVITY; EXTRACELLULAR CALCIUM; FEMALE; FLOW CYTOMETRY; HISTOLOGY; HOMEOSTASIS; IN VITRO STUDY; IN VIVO STUDY; MALE; MICRO-COMPUTED TOMOGRAPHY; MOUSE; NONHUMAN; OSSIFICATION; OSTEOBLAST; OSTEOCLAST; OSTEOCLAST ACTIVITY; OSTEOCLASTOGENESIS; OSTEOLYSIS; PROTEIN FUNCTION; WESTERN BLOTTING; ANIMAL; BONE; CYTOLOGY; FLUORESCENCE MICROSCOPY; GENETICS; METABOLISM; MUTAGENESIS; MUTATION; PHENOTYPE; TRANSGENIC MOUSE;

MUS;

ANIMALS; BONE AND BONES; BONE DENSITY; BONE RESORPTION; CALCIUM; CELL PROLIFERATION; CHOLINE KINASE; HOMEOSTASIS; MICE; MICE, TRANSGENIC; MICROSCOPY, FLUORESCENCE; MUTAGENESIS; MUTATION; OSTEOBLASTS; OSTEOCLASTS; PHENOTYPE; PHOSPHORYLCHOLINE; X-RAY MICROTOMOGRAPHY;

EID: 84922264807     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M114.567966     Document Type: Article

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