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Volumn 365, Issue 2, 2008, Pages 252-257

MKK6-p38 MAPK signaling pathway enhances survival but not bone-resorbing activity of osteoclasts

Author keywords

Bone resorption; Cell survival; Inflammation; Interleukin 1; MKK6; Osteoclasts; p38 MAP kinase

Indexed keywords

MITOGEN ACTIVATED PROTEIN KINASE KINASE 6; MITOGEN ACTIVATED PROTEIN KINASE P38;

EID: 36249022727     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2007.10.169     Document Type: Article
Times cited : (23)

References (30)
  • 1
    • 0037673945 scopus 로고    scopus 로고
    • Osteoclast differentiation and activation
    • Boyle W.J., Simonet W.S., and Lacey D.L. Osteoclast differentiation and activation. Nature 423 (2003) 337-342
    • (2003) Nature , vol.423 , pp. 337-342
    • Boyle, W.J.1    Simonet, W.S.2    Lacey, D.L.3
  • 2
    • 0033304730 scopus 로고    scopus 로고
    • Modulation of osteoclast differentiation and function by the new members of the tumor necrosis factor receptor and ligand families
    • Suda T., Takahashi N., Udagawa N., Jimi E., Gillespie M.T., and Martin T.J. Modulation of osteoclast differentiation and function by the new members of the tumor necrosis factor receptor and ligand families. Endocr. Rev. 20 (1999) 345-357
    • (1999) Endocr. Rev. , vol.20 , pp. 345-357
    • Suda, T.1    Takahashi, N.2    Udagawa, N.3    Jimi, E.4    Gillespie, M.T.5    Martin, T.J.6
  • 7
    • 0032502353 scopus 로고    scopus 로고
    • Activation of NF-kappaB is involved in the survival of osteoclasts promoted by interleukin-1
    • Jimi E., Nakamura I., Ikebe T., Akiyama S., Takahashi N., and Suda T. Activation of NF-kappaB is involved in the survival of osteoclasts promoted by interleukin-1. J. Biol. Chem. 273 (1998) 8799-8805
    • (1998) J. Biol. Chem. , vol.273 , pp. 8799-8805
    • Jimi, E.1    Nakamura, I.2    Ikebe, T.3    Akiyama, S.4    Takahashi, N.5    Suda, T.6
  • 8
    • 0033602023 scopus 로고    scopus 로고
    • Interleukin 1 induces multinucleation and bone-resorbing activity of osteoclasts in the absence of osteoblasts/stromal cells
    • Jimi E., Nakamura I., Duong L.T., Ikebe T., Takahashi N., Rodan G.A., and Suda T. Interleukin 1 induces multinucleation and bone-resorbing activity of osteoclasts in the absence of osteoblasts/stromal cells. Exp. Cell Res. 247 (1999) 84-93
    • (1999) Exp. Cell Res. , vol.247 , pp. 84-93
    • Jimi, E.1    Nakamura, I.2    Duong, L.T.3    Ikebe, T.4    Takahashi, N.5    Rodan, G.A.6    Suda, T.7
  • 9
    • 0345772095 scopus 로고    scopus 로고
    • Lipopolysaccharide promotes the survival of osteoclasts via Toll-like receptor 4, but cytokine production of osteoclasts in response to lipopolysaccharide is different from that of macrophages
    • Itoh K., Udagawa N., Kobayashi K., Suda K., Li X., Takami M., Okahashi N., Nishihara T., and Takahashi N. Lipopolysaccharide promotes the survival of osteoclasts via Toll-like receptor 4, but cytokine production of osteoclasts in response to lipopolysaccharide is different from that of macrophages. J. Immunol. 170 (2003) 3688-3695
    • (2003) J. Immunol. , vol.170 , pp. 3688-3695
    • Itoh, K.1    Udagawa, N.2    Kobayashi, K.3    Suda, K.4    Li, X.5    Takami, M.6    Okahashi, N.7    Nishihara, T.8    Takahashi, N.9
  • 12
    • 0033485739 scopus 로고    scopus 로고
    • Differential role for p38 mitogen-activated protein kinase in regulating CD40-induced gene expression in dendritic cells and B cells
    • Aicher A., Shu G.L., Magaletti D., Mulvania T., Pezzutto A., Craxton A., and Clark E.A. Differential role for p38 mitogen-activated protein kinase in regulating CD40-induced gene expression in dendritic cells and B cells. J. Immunol. 163 (1999) 5786-5795
    • (1999) J. Immunol. , vol.163 , pp. 5786-5795
    • Aicher, A.1    Shu, G.L.2    Magaletti, D.3    Mulvania, T.4    Pezzutto, A.5    Craxton, A.6    Clark, E.A.7
  • 13
    • 33750298315 scopus 로고    scopus 로고
    • FGF1/p38 MAP kinase inhibitor therapy induces cardiomyocyte mitosis, reduces scarring, and rescues function after myocardial infarction
    • Engel F.B., Hsieh P.C., Lee R.T., and Keating M.T. FGF1/p38 MAP kinase inhibitor therapy induces cardiomyocyte mitosis, reduces scarring, and rescues function after myocardial infarction. Proc. Natl. Acad. Sci. USA 103 (2006) 15546-15551
    • (2006) Proc. Natl. Acad. Sci. USA , vol.103 , pp. 15546-15551
    • Engel, F.B.1    Hsieh, P.C.2    Lee, R.T.3    Keating, M.T.4
  • 14
    • 0033610788 scopus 로고    scopus 로고
    • Specific inhibitors of p38 mitogen-activated protein kinase block 3T3-L1 adipogenesis
    • Engelman J.A., Lisanti M.P., and Scherer P.E. Specific inhibitors of p38 mitogen-activated protein kinase block 3T3-L1 adipogenesis. J. Biol. Chem. 273 (1998) 32111-32120
    • (1998) J. Biol. Chem. , vol.273 , pp. 32111-32120
    • Engelman, J.A.1    Lisanti, M.P.2    Scherer, P.E.3
  • 15
    • 0032544550 scopus 로고    scopus 로고
    • Requirement of p38 mitogen-activated protein kinase for neuronal differentiation in PC12 cells
    • Morooka T., and Nishida E. Requirement of p38 mitogen-activated protein kinase for neuronal differentiation in PC12 cells. J. Biol. Chem. 273 (1998) 24285-24288
    • (1998) J. Biol. Chem. , vol.273 , pp. 24285-24288
    • Morooka, T.1    Nishida, E.2
  • 16
    • 0242552020 scopus 로고    scopus 로고
    • p38 Mitogen-activated protein kinase is crucially involved in osteoclast differentiation but not in cytokine production, phagocytosis, or dendritic cell differentiation of bone marrow macrophages
    • Li X., Udagawa N., Takami M., Sato N., Kobayashi Y., and Takahashi N. p38 Mitogen-activated protein kinase is crucially involved in osteoclast differentiation but not in cytokine production, phagocytosis, or dendritic cell differentiation of bone marrow macrophages. Endocrinology 144 (2003) 4999-5005
    • (2003) Endocrinology , vol.144 , pp. 4999-5005
    • Li, X.1    Udagawa, N.2    Takami, M.3    Sato, N.4    Kobayashi, Y.5    Takahashi, N.6
  • 17
    • 0031114081 scopus 로고    scopus 로고
    • Actions of IL-1 are selectively controlled by p38 mitogen-activated protein kinase: regulation of prostaglandin H synthase-2, metalloproteinases, and IL-6 at different levels
    • Ridley S.H., Sarsfield S.J., Lee J.C., Bigg H.F., Cawston T.E., Taylor D.J., DeWitt D.L., and Saklatvala J. Actions of IL-1 are selectively controlled by p38 mitogen-activated protein kinase: regulation of prostaglandin H synthase-2, metalloproteinases, and IL-6 at different levels. J. Immunol. 158 (1997) 3165-3173
    • (1997) J. Immunol. , vol.158 , pp. 3165-3173
    • Ridley, S.H.1    Sarsfield, S.J.2    Lee, J.C.3    Bigg, H.F.4    Cawston, T.E.5    Taylor, D.J.6    DeWitt, D.L.7    Saklatvala, J.8
  • 18
    • 0030051528 scopus 로고    scopus 로고
    • MKK3- and MKK6-regulated gene expression is mediated by the p38 mitogen-activated protein kinase signal transduction pathway
    • Raingeaud J., Whitmarsh A.J., Barrett T., Derijard B., and Davis R.J. MKK3- and MKK6-regulated gene expression is mediated by the p38 mitogen-activated protein kinase signal transduction pathway. Mol. Cell. Biol. 16 (1996) 1247-1255
    • (1996) Mol. Cell. Biol. , vol.16 , pp. 1247-1255
    • Raingeaud, J.1    Whitmarsh, A.J.2    Barrett, T.3    Derijard, B.4    Davis, R.J.5
  • 20
    • 0036321005 scopus 로고    scopus 로고
    • p38 MAPK-mediated signals are required for inducing osteoclast differentiation but not for osteoclast function
    • Li X., Udagawa N., Itoh K., Suda K., Murase Y., Nishihara T., Suda T., and Takahashi N. p38 MAPK-mediated signals are required for inducing osteoclast differentiation but not for osteoclast function. Endocrinology 143 (2002) 3105-3113
    • (2002) Endocrinology , vol.143 , pp. 3105-3113
    • Li, X.1    Udagawa, N.2    Itoh, K.3    Suda, K.4    Murase, Y.5    Nishihara, T.6    Suda, T.7    Takahashi, N.8
  • 21
    • 0034613188 scopus 로고    scopus 로고
    • Involvement of p38 mitogen-activated protein kinase signaling pathway in osteoclastogenesis mediated by receptor activator of NF-kappa B ligand (RANKL)
    • Matsumoto M., Sudo T., Saito T., Osada H., and Tsujimoto M. Involvement of p38 mitogen-activated protein kinase signaling pathway in osteoclastogenesis mediated by receptor activator of NF-kappa B ligand (RANKL). J. Biol. Chem. 275 (2000) 31155-31161
    • (2000) J. Biol. Chem. , vol.275 , pp. 31155-31161
    • Matsumoto, M.1    Sudo, T.2    Saito, T.3    Osada, H.4    Tsujimoto, M.5
  • 26
    • 33748168693 scopus 로고    scopus 로고
    • Coordination of microtubules and the actin cytoskeleton is important in osteoclast function, but calcitonin disrupts sealing zones without affecting microtubule networks
    • Okumura S., Mizoguchi T., Sato N., Yamaki M., Kobayashi Y., Yamauchi H., Ozawa H., Udagawa N., and Takahashi N. Coordination of microtubules and the actin cytoskeleton is important in osteoclast function, but calcitonin disrupts sealing zones without affecting microtubule networks. Bone 39 (2006) 684-693
    • (2006) Bone , vol.39 , pp. 684-693
    • Okumura, S.1    Mizoguchi, T.2    Sato, N.3    Yamaki, M.4    Kobayashi, Y.5    Yamauchi, H.6    Ozawa, H.7    Udagawa, N.8    Takahashi, N.9
  • 27
    • 0033136947 scopus 로고    scopus 로고
    • The role of p38 mitogen-activated protein kinase in IL-1 beta transcription
    • Baldassare J.J., Bi Y., and Bellone C.J. The role of p38 mitogen-activated protein kinase in IL-1 beta transcription. J. Immunol. 162 (1999) 5367-5373
    • (1999) J. Immunol. , vol.162 , pp. 5367-5373
    • Baldassare, J.J.1    Bi, Y.2    Bellone, C.J.3
  • 28
    • 24944554790 scopus 로고    scopus 로고
    • Signaling pathways and genes that inhibit pathogen-induced macrophage apoptosis-CREB and NF-kappaB as key regulators
    • Park J.M., Greten F.R., Wong A., Westrick R.J., Arthur J.S., Otsu K., Hoffmann A., Montminy M., and Karin M. Signaling pathways and genes that inhibit pathogen-induced macrophage apoptosis-CREB and NF-kappaB as key regulators. Immunity 23 (2005) 319-329
    • (2005) Immunity , vol.23 , pp. 319-329
    • Park, J.M.1    Greten, F.R.2    Wong, A.3    Westrick, R.J.4    Arthur, J.S.5    Otsu, K.6    Hoffmann, A.7    Montminy, M.8    Karin, M.9


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.