Loss of skeletal mineralization by the simultaneous ablation of PHOSPHO1 and alkaline phosphatase function: A unified model of the mechanisms of initiation of skeletal calcification

Journal of Bone and Mineral Research

Volumn 26, Issue 2, 2011, Pages 286-297

  Yadav, Manisha C ^a   Simão, Ana Maria Sper ^a   Narisawa, Sonoko ^a   Huesa, Carmen ^b   McKee, Marc D ^c   Farquharson, Colin ^b   Millán, José Luis ^a  

^a BURNHAM INSTITUTE   (United States)

^b UNIVERSITY OF EDINBURGH   (United Kingdom)

^c MCGILL UNIVERSITY   (Canada)

Author keywords

AKP2; BIOMINERALIZATION; CALCIFICATION; HYPOPHOSPHATASIA; OSTEOIDOSIS; OSTEOMALACIA; SCOLIOSIS; TNAP

Indexed keywords

ALKALINE PHOSPHATASE; PHOSPHOPROTEIN PHOSPHATASE; PYROPHOSPHATE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BIOMINERALIZATION; BONE MINERALIZATION; CALCIFICATION; CARTILAGE CELL; CONTROLLED STUDY; MOLECULAR MODEL; MOUSE; NONHUMAN; OSSIFICATION; OSTEOMALACIA; PROTEIN EXPRESSION; PROTEIN FUNCTION; SCOLIOSIS;

ALKALINE PHOSPHATASE; ANIMALS; BONE AND BONES; BONE DENSITY; CALCIFICATION, PHYSIOLOGIC; COLLAGEN; DIPHOSPHATES; EXTRACELLULAR MATRIX; MICE; MICE, INBRED C3H; MICE, INBRED C57BL; MICE, TRANSGENIC; MUTATION; PHOSPHORIC DIESTER HYDROLASES; PHOSPHORIC MONOESTER HYDROLASES; PYROPHOSPHATASES;

EID: 79251482785     PISSN: 08840431     EISSN: None     Source Type: Journal    
DOI: 10.1002/jbmr.195     Document Type: Article

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