The MEKK1 PHD ubiquitinates TAB1 to activate MAPKs in response to cytokines

EMBO Journal

Volumn 33, Issue 21, 2014, Pages 2581-2596

  Charlaftis, Nikolaos ^a   Suddason, Tesha ^a   Wu, Xuefeng ^b   Anwar, Saba ^a   Karin, Michael ^b   Gallagher, Ewen ^a  

^a IMPERIAL COLLEGE LONDON   (United Kingdom)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

differentiation; signalling; stem cell; tumourigenesis; ubiquitin

Indexed keywords

DEUBIQUITINASE; EPIDERMAL GROWTH FACTOR; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE KINASE KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE P38; PROTEIN; STRESS ACTIVATED PROTEIN KINASE; TAB1 PROTEIN; TRANSFORMING GROWTH FACTOR BETA; TUMOR NECROSIS FACTOR RECEPTOR ASSOCIATED FACTOR 2; UNCLASSIFIED DRUG; MITOGEN ACTIVATED PROTEIN KINASE KINASE 4; POLYUBIQUITIN; PROTEIN BINDING; SIGNAL TRANSDUCING ADAPTOR PROTEIN; TAB1 PROTEIN, MOUSE;

AMINO ACID SEQUENCE; ANIMAL CELL; ARTICLE; B LYMPHOCYTE; CARCINOGENESIS; CELL DIFFERENTIATION; CYTOKINE RESPONSE; EMBRYONIC STEM CELL; ENZYME STRUCTURE; ENZYME SUBSTRATE; GENE TARGETING; HEART; HYPEROSMOTIC STRESS; MICROTUBULE; MOLECULAR MODEL; MOUSE; NONHUMAN; PHD DOMAIN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN FUNCTION; PROTEIN MICROARRAY; PROTEIN PHOSPHORYLATION; PROTEIN PURIFICATION; PROTEIN STABILITY; PROTEIN TRANSPORT; SIGNAL TRANSDUCTION; UBIQUITINATION; ANIMAL; CELL TRANSFORMATION; CYTOLOGY; GENETICS; KNOCKOUT MOUSE; METABOLISM; PHYSIOLOGY; PROTEIN MOTIF;

MUS;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; AMINO ACID MOTIFS; ANIMALS; CELL DIFFERENTIATION; CELL TRANSFORMATION, NEOPLASTIC; EMBRYONIC STEM CELLS; EPIDERMAL GROWTH FACTOR; MAP KINASE KINASE 4; MAP KINASE KINASE KINASE 1; MAP KINASE SIGNALING SYSTEM; MICE; MICE, KNOCKOUT; P38 MITOGEN-ACTIVATED PROTEIN KINASES; POLYUBIQUITIN; PROTEIN BINDING; TRANSFORMING GROWTH FACTOR BETA; UBIQUITINATION;

EID: 84922252988     PISSN: 02614189     EISSN: 14602075     Source Type: Journal    
DOI: 10.15252/embj.201488351     Document Type: Article

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