A neuron-specific deletion of the microRNA-processing enzyme dicer induces severe but transient obesity in mice

PLoS ONE

Volumn 10, Issue 1, 2015, Pages

  Mang, Géraldine M ^a   Pradervand, Sylvain ^a,b   Du, Ngoc Hien ^a   Arpat, Alaaddin Bulak ^a,b   Preitner, Frédéric ^a   Wigger, Leonore ^a,b   Gatfield, David ^a   Franken, Paul ^a  

^a UNIVERSITY OF LAUSANNE   (Switzerland)

^b SWISS INSTITUTE OF BIOINFORMATICS   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

DICER; MICRORNA; TRANSCRIPTOME; RIBONUCLEASE III; TAMOXIFEN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BASAL METABOLIC RATE; BODY COMPOSITION; BRAIN CORTEX; CONTROLLED STUDY; DISEASE SEVERITY; EXON; FAT MASS; FOOD DEPRIVATION; GENE CLUSTER; GENE DELETION; GENETIC RECOMBINATION; HYPERPHAGIA; LUNG GAS EXCHANGE; MOUSE; NERVE CELL PLASTICITY; NONHUMAN; OBESITY; OXYGEN CONSUMPTION; PHENOTYPE; TRANSGENE; WEIGHT GAIN; ANIMAL; ANTIBODY SPECIFICITY; BRAIN; DIET RESTRICTION; GENE SILENCING; GENETIC ASSOCIATION STUDY; GENETICS; GENOTYPE; KNOCKOUT MOUSE; LOCOMOTION; METABOLISM; NERVE CELL;

MUS;

ANIMALS; BASAL METABOLISM; BRAIN; EXONS; FASTING; GENE DELETION; GENE KNOCKDOWN TECHNIQUES; GENETIC ASSOCIATION STUDIES; GENOTYPE; HYPERPHAGIA; LOCOMOTION; MICE; MICE, KNOCKOUT; MICRORNAS; NEURONS; OBESITY; ORGAN SPECIFICITY; PHENOTYPE; RIBONUCLEASE III; TAMOXIFEN; TRANSCRIPTOME;

EID: 84922170794     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0116760     Document Type: Article

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