The molecular mechanism of rotenone-induced α-synuclein aggregation: EMPHASIZING the role of the calcium/GSK3β pathway

Toxicology Letters

Volumn 233, Issue 2, 2015, Pages 163-171

  Yuan, Yu he ^a   Yan, Wen fen ^a   Sun, Jian dong ^a   Huang, Ju yang ^a   Mu, Zheng ^a   Chen, Nai Hong ^a  

^a INSTITUTE OF MATERIA MEDICA   (China)

Author keywords

Calcium; GSK3 ; Parkinson's disease; Rotenone; Synuclein

Indexed keywords

ALPHA SYNUCLEIN; CALCIUM; GLYCOGEN SYNTHASE KINASE 3BETA; ROTENONE; GLYCOGEN SYNTHASE KINASE 3; GLYCOGEN SYNTHASE KINASE 3 BETA; INSECTICIDE; UNCOUPLING PROTEIN;

ADULT; ANIMAL EXPERIMENT; ARTICLE; ATTENUATION; AUTOPHAGY; CALCIUM CELL LEVEL; CONTROLLED STUDY; CROSS LINKING; ELECTRON MICROSCOPY; ENZYME ACTIVATION; ENZYME ACTIVITY; EXPOSURE; GENE OVEREXPRESSION; IMMUNOFLUORESCENCE; MALE; MOUSE; NONHUMAN; PC12 CELL LINE; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; WESTERN BLOTTING; ANIMAL; ANTAGONISTS AND INHIBITORS; C57BL MOUSE; DOSE RESPONSE; DRUG EFFECTS; METABOLISM; MICROINJECTION; RAT; SUBSTANTIA NIGRA;

ANIMALIA;

ALPHA-SYNUCLEIN; ANIMALS; AUTOPHAGY; CALCIUM; DOSE-RESPONSE RELATIONSHIP, DRUG; GLYCOGEN SYNTHASE KINASE 3; INSECTICIDES; MALE; MICE; MICE, INBRED C57BL; MICROINJECTIONS; PC12 CELLS; RATS; ROTENONE; SIGNAL TRANSDUCTION; SUBSTANTIA NIGRA; UNCOUPLING AGENTS;

EID: 84922169955     PISSN: 03784274     EISSN: 18793169     Source Type: Journal    
DOI: 10.1016/j.toxlet.2014.11.029     Document Type: Article

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