Identification of a non-growth factor role for GM-CSF in advanced atherosclerosis: Promotion of macrophage apoptosis and plaque necrosis through IL-23 signaling

Circulation Research

Volumn 116, Issue 2, 2015, Pages e13-e24

  Subramanian, Manikandan ^a   Thorp, Edward ^b   Tabas, Ira ^a  

^a Och Spine at New York Presbyterian Hospitals   (United States)

^b NORTHWESTERN UNIVERSITY   (United States)

Author keywords

apoptosis; atherosclerosis; cytokines; granulocyte macrophage colony stimulating factor; intercellular signaling peptides and proteins; interleukin 23

Indexed keywords

GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; INTERLEUKIN 23; LOW DENSITY LIPOPROTEIN; PROTEASOME; PROTEIN BCL 2; SIGNAL PEPTIDE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; AORTA ROOT; APOPTOSIS; ARTICLE; ATHEROSCLEROSIS; ATHEROSCLEROTIC PLAQUE; CELL SURVIVAL; CONTROLLED STUDY; CYTOKINE PRODUCTION; DISEASE COURSE; IN VITRO STUDY; IN VIVO STUDY; MACROPHAGE; MOUSE; NONHUMAN; OXIDATIVE STRESS; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN DEGRADATION; SIGNAL TRANSDUCTION; ANIMAL; C57BL MOUSE; DEFICIENCY; KNOCKOUT MOUSE; METABOLISM; NECROSIS; PATHOLOGY; PHYSIOLOGY;

ANIMALS; APOPTOSIS; GRANULOCYTE-MACROPHAGE COLONY-STIMULATING FACTOR; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; INTERLEUKIN-23; MACROPHAGES; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; NECROSIS; PLAQUE, ATHEROSCLEROTIC; SIGNAL TRANSDUCTION;

EID: 84922105349     PISSN: 00097330     EISSN: 15244571     Source Type: Journal    
DOI: 10.1161/CIRCRESAHA.116.304794     Document Type: Article

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