Reactive oxygen species and death: Oxidative DNA damage in atherosclerosis

Circulation Research

Volumn 88, Issue 7, 2001, Pages 648-650

  Bennett, M R ^a  

^a ADDENBROOKE S HOSPITAL   (United Kingdom)

Author keywords

Apoptosis; DNA repair; p53; Reactive oxygen species

Indexed keywords

LOW DENSITY LIPOPROTEIN; REACTIVE OXYGEN METABOLITE;

APOPTOSIS; ATHEROGENESIS; ATHEROSCLEROSIS; DEATH; DNA DAMAGE; DNA STRAND BREAKAGE; EDITORIAL; HUMAN; LIPID OXIDATION; MACROPHAGE; MORTALITY; OXIDATION; PRIORITY JOURNAL;

EID: 0035853412     PISSN: 00097330     EISSN: None     Source Type: Journal    
DOI: 10.1161/hh0701.089955     Document Type: Editorial

References (25)

1. Increased NADH-oxidase-mediated superoxide production in the early stages of atherosclerosis: Evidence for involvement of the renin-angiotensin system
2. Interactions between NO and reactive oxygen species: Pathophysiological importance in atherosclerosis, hypertension, diabetes anal heart failure
3. Oxidatively modified low density lipoproteins: A potential role in recruitment and retention of monocyte/macrophages during atherogenesis
4. The yin and yang of oxidation in the development of the fatty streak
5. A macrophage receptor for oxidised low-density lipoprotein distinct from the receptor for acetyl low-density lipoprotein: Partial purification and role in recognition of oxidatively damaged cells
6. Macrophage scavenger receptor CD36 is the major receptor for LDL modified by monocyte-generated reactive nitrogen species
7. DNA damage in deoxynucleosides and oligonucleotides treated with peroxynitrite
8. A role for p53 in base excision repair
9. Differential effect of hydrogen peroxide and superoxide anion on apoptosis and proliferation of vascular smooth muscle cells
10. Oxidative DNA damage and repair in experimental atherosclerosis are reversed by dietary lipid lowering
11. Biphasic pattern of cell turnover characterizes the progression from fatty streaks to ruptured human atherosclerotic plaques
12. The absence of p53 accelerates atherosclerosis by increasing cell proliferation in vivo
13. Characterization of apoptotic macrophages in atheromatous tissue of humans and heritable hyperlipidemic rabbits
14. Increased expression of matrix metalloproteinases and matrix-degrading activity in vulnerable regions of human atherosclerotic plaques
15. Apoptosis of vascular smooth-muscle cells induced by in vitro stimulation with interferon-γ, tumor necrosis factor-α, and interleukin-1β
16. Pravastatin treatment increases collagen content and decreases lipid content, inflammation, metalloproteinases, and cell death in human carotid plaques: Implications for plaque stabilization
17. Lipid lowering by diet reduces matrix metalloproteinase activity and increases collagen content of rabbit atheroma: A potential mechanism of lesion stabilization
18. Localization of apoptotic macrophages at the site of plaque rupture in sudden coronary death
19. Apoptosis and related proteins in different stages of human atherosclerotic plaques
20. Shed membrane microparticles with procoagulant potential in human atherosclerotic plaques: A role for apoptosis in plaque thrombogenicity
21. Evidence for apoptosis in advanced human atheroma: Colocalization with interleukin-1β converting enzyme
22. Role of smooth muscle cell death in advanced coronary primary lesions: Implications for plaque instability
23. Thrombin generation by apoptotic vascular smooth muscle cells
24. Fas/FADD-mediated activation of a specific program of inflammatory gene expression in vascular smooth muscle cells
25. Increased sensitivity of human vascular smooth muscle cells from atherosclerotic plaque to p53-mediated apoptosis