GM-CSF deficiency reduces macrophage PPAR-γ expression and aggravates atherosclerosis in ApoE-deficient mice

Arteriosclerosis, Thrombosis, and Vascular Biology

Volumn 26, Issue 10, 2006, Pages 2337-2344

  Ditiatkovski, Michael ^a,b,c   Toh, Ban Hock ^b   Bobik, Alex ^a  

^a MONASH UNIVERSITY   (Australia)

^b MONASH UNIVERSITY   (Australia)

^c BAKER IDI HEART AND DIABETES INSTITUTE   (Australia)

Author keywords

apoE mice; Atherosclerotic lesions; GM CSF deficiency; Hyperlipidemia; Inflammatory cytokines; PPAR

Indexed keywords

ABC TRANSPORTER A1; APOLIPOPROTEIN E; CD36 ANTIGEN; COLLAGEN; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; MONOCYTE CHEMOTACTIC PROTEIN 1; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; RECEPTOR BLOCKING AGENT; TUMOR NECROSIS FACTOR ALPHA; VASCULAR CELL ADHESION MOLECULE 1;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; AORTA SINUS; ARTICLE; ATHEROSCLEROSIS; CHOLESTEROL BLOOD LEVEL; CHOLESTEROL TRANSPORT; CONTROLLED STUDY; GENE CONTROL; GENE EXPRESSION; HYPERLIPIDEMIA; MACROPHAGE; MALE; MOUSE; MOUSE STRAIN; NONHUMAN; PERITONEUM MACROPHAGE; PRIORITY JOURNAL; SMOOTH MUSCLE FIBER; VASCULARIZATION;

ANIMALS; APOLIPOPROTEINS E; ATHEROSCLEROSIS; ATP-BINDING CASSETTE TRANSPORTERS; CHEMOKINE CCL2; CHOLESTEROL; COLLAGEN; GRANULOCYTE-MACROPHAGE COLONY-STIMULATING FACTOR; HYPERLIPIDEMIAS; MACROPHAGES; MACROPHAGES, PERITONEAL; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; NEOVASCULARIZATION, PATHOLOGIC; PPAR GAMMA; SINUS OF VALSALVA; TUMOR NECROSIS FACTOR-ALPHA; UP-REGULATION; VASCULAR CELL ADHESION MOLECULE-1;

EID: 33749060898     PISSN: 10795642     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.ATV.0000238357.60338.90     Document Type: Article

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