Conditional density-based analysis of T cell signaling in single-cell data

Science

Volumn 346, Issue 6213, 2014, Pages

  Krishnaswamy, Smita ^a   Spitzer, Matthew H ^b   Mingueneau, Michael ^c   Bendall, Sean C ^b   Litvin, Oren ^a   Stone, Erica ^d   Pe'Er, Dana ^a   Nolan, Garry P ^a  

^a Och Spine at New York Presbyterian Hospitals   (United States)

^b STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c HARVARD MEDICAL SCHOOL   (United States)

^d UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

B LYMPHOCYTE RECEPTOR; CD28 ANTIGEN; CD3 ANTIGEN; CD4 ANTIGEN; HERMES ANTIGEN; MITOGEN ACTIVATED PROTEIN KINASE 1; PROTEIN KINASE ZAP 70; PROTEIN S6; PROTEIN SH2; T LYMPHOCYTE RECEPTOR; LYMPHOCYTE ANTIGEN RECEPTOR; MAPK1 PROTEIN, MOUSE; PERK KINASE; PROTEIN KINASE R; RIBOSOMAL PROTEIN S6, MOUSE;

CELLS AND CELL COMPONENTS; ENZYME ACTIVITY; MOLECULAR ANALYSIS; PROTEIN; RODENT; STATISTICAL ANALYSIS;

ANIMAL CELL; ARTICLE; CD4+ T LYMPHOCYTE; CELL DENSITY; FLOW CYTOMETRY; LYMPHOCYTE DIFFERENTIATION; MATHEMATICAL ANALYSIS; MEMORY T LYMPHOCYTE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; SINGLE CELL ANALYSIS; ANIMAL; COMPUTER SIMULATION; GENETICS; IMAGE CYTOMETRY; IMMUNOLOGY; MALE; METABOLISM; MUTANT MOUSE STRAIN; PROCEDURES; SYSTEMS BIOLOGY; VALIDATION STUDY;

MUS;

ANIMALS; CD4-POSITIVE T-LYMPHOCYTES; COMPUTER SIMULATION; EIF-2 KINASE; IMAGE CYTOMETRY; MALE; MICE; MICE, MUTANT STRAINS; MITOGEN-ACTIVATED PROTEIN KINASE 1; RECEPTORS, ANTIGEN, T-CELL; RIBOSOMAL PROTEIN S6; SIGNAL TRANSDUCTION; SINGLE-CELL ANALYSIS; SYSTEMS BIOLOGY;

EID: 84922059501     PISSN: 00368075     EISSN: 10959203     Source Type: Journal    
DOI: 10.1126/science.1250689     Document Type: Article

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