메뉴 건너뛰기




Volumn 46, Issue 10, 2014, Pages 1103-1109

A meta-analysis of 87,040 individuals identifies 23 new susceptibility loci for prostate cancer

(164)  Olama, Ali Amin Al a   Kote Jarai, Zsofia b   Berndt, Sonja I c   Conti, David V d,e   Schumacher, Fredrick d,e   Han, Ying d   Benlloch, Sara a   Hazelett, Dennis J d,e   Wang, Zhaoming c,f   Saunders, Ed b   Leongamornlert, Daniel b   Lindstrom, Sara g   Jugurnauth Little, Sara b   Dadaev, Tokhir b   Tymrakiewicz, Malgorzata b   Stram, Daniel O d,e   Rand, Kristin d   Wan, Peggy d   Stram, Alex d   Sheng, Xin d   more..


Author keywords

[No Author keywords available]

Indexed keywords

CYCLIN DEPENDENT KINASE INHIBITOR 2A; CYCLIN DEPENDENT KINASE INHIBITOR 2B; LONG UNTRANSLATED RNA; PROSTATE SPECIFIC ANTIGEN; STAT1 PROTEIN; TRANSCRIPTION FACTOR ERG;

EID: 84922011640     PISSN: 10614036     EISSN: 15461718     Source Type: Journal    
DOI: 10.1038/ng.3094     Document Type: Article
Times cited : (384)

References (48)
  • 1
    • 84893759915 scopus 로고    scopus 로고
    • The genetic epidemiology of prostate cancer and its clinical implications
    • Eeles, R. et al. The genetic epidemiology of prostate cancer and its clinical implications. Nat. Rev. Urol. 11, 18-31 (2014).
    • (2014) Nat. Rev. Urol. , vol.11 , pp. 18-31
    • Eeles, R.1
  • 2
    • 84875739291 scopus 로고    scopus 로고
    • Identifcation of 23 new prostate cancer susceptibility loci using the iCOGS custom genotyping array
    • Eeles, R.A. et al. Identifcation of 23 new prostate cancer susceptibility loci using the iCOGS custom genotyping array. Nat. Genet. 45, 385-391 (2013).
    • (2013) Nat. Genet. , vol.45 , pp. 385-391
    • Eeles, R.A.1
  • 3
    • 77954133026 scopus 로고    scopus 로고
    • Estimation of effect size distribution from genome-wide association studies and implications for future discoveries
    • Park, J.H. et al. Estimation of effect size distribution from genome-wide association studies and implications for future discoveries. Nat. Genet. 42, 570-575 (2010).
    • (2010) Nat. Genet. , vol.42 , pp. 570-575
    • Park, J.H.1
  • 4
    • 39749129053 scopus 로고    scopus 로고
    • Multiple newly identifed loci associated with prostate cancer susceptibility
    • Eeles, R.A. et al. Multiple newly identifed loci associated with prostate cancer susceptibility. Nat. Genet. 40, 316-321 (2008).
    • (2008) Nat. Genet. , vol.40 , pp. 316-321
    • Eeles, R.A.1
  • 5
    • 70349547128 scopus 로고    scopus 로고
    • Genome-wide association and replication studies identify four variants associated with prostate cancer susceptibility
    • Gudmundsson, J. et al. Genome-wide association and replication studies identify four variants associated with prostate cancer susceptibility. Nat. Genet. 41, 1122-1126 (2009).
    • (2009) Nat. Genet. , vol.41 , pp. 1122-1126
    • Gudmundsson, J.1
  • 6
    • 80052716147 scopus 로고    scopus 로고
    • Genome-wide association study identifes new prostate cancer susceptibility loci
    • Schumacher, F.R. et al. Genome-wide association study identifes new prostate cancer susceptibility loci. Hum. Mol. Genet. 20, 3867-3875 (2011).
    • (2011) Hum. Mol. Genet. , vol.20 , pp. 3867-3875
    • Schumacher, F.R.1
  • 7
    • 39749118602 scopus 로고    scopus 로고
    • Multiple loci identifed in a genome-wide association study of prostate cancer
    • Thomas, G. et al. Multiple loci identifed in a genome-wide association study of prostate cancer. Nat. Genet. 40, 310-315 (2008).
    • (2008) Nat. Genet. , vol.40 , pp. 310-315
    • Thomas, G.1
  • 8
    • 84869211006 scopus 로고    scopus 로고
    • Evaluating genetic risk for prostate cancer among Japanese and Latinos
    • Cheng, I. et al. Evaluating genetic risk for prostate cancer among Japanese and Latinos. Cancer Epidemiol. Biomarkers Prev. 21, 2048-2058 (2012).
    • (2012) Cancer Epidemiol. Biomarkers Prev. , vol.21 , pp. 2048-2058
    • Cheng, I.1
  • 9
    • 79958015711 scopus 로고    scopus 로고
    • Characterizing genetic risk at known prostate cancer susceptibility loci in African Americans
    • Haiman, C.A. et al. Characterizing genetic risk at known prostate cancer susceptibility loci in African Americans. PLoS Genet. 7, e1001387 (2011).
    • (2011) PLoS Genet. , vol.7 , pp. e1001387
    • Haiman, C.A.1
  • 10
    • 38449103390 scopus 로고    scopus 로고
    • Two genome-wide association studies of aggressive prostate cancer implicate putative prostate tumor suppressor gene DAB2IP
    • Duggan, D. et al. Two genome-wide association studies of aggressive prostate cancer implicate putative prostate tumor suppressor gene DAB2IP. J. Natl. Cancer Inst. 99, 1836-1844 (2007).
    • (2007) J. Natl. Cancer Inst. , vol.99 , pp. 1836-1844
    • Duggan, D.1
  • 11
    • 79957581659 scopus 로고    scopus 로고
    • Genome-wide association study of prostate cancer in men of African ancestry identifes a susceptibility locus at 17q21
    • Haiman, C.A. et al. Genome-wide association study of prostate cancer in men of African ancestry identifes a susceptibility locus at 17q21. Nat. Genet. 43, 570-573 (2011).
    • (2011) Nat. Genet. , vol.43 , pp. 570-573
    • Haiman, C.A.1
  • 12
    • 84899620648 scopus 로고    scopus 로고
    • A genome-wide association study of prostate cancer in West African men
    • Cook, M.B. et al. A genome-wide association study of prostate cancer in West African men. Hum. Genet. 133, 509-521 (2014).
    • (2014) Hum. Genet. , vol.133 , pp. 509-521
    • Cook, M.B.1
  • 13
    • 84862825777 scopus 로고    scopus 로고
    • Common variants at 11q12, 10q26 and 3p11.2 are associated with prostate cancer susceptibility in Japanese
    • Akamatsu, S. et al. Common variants at 11q12, 10q26 and 3p11.2 are associated with prostate cancer susceptibility in Japanese. Nat. Genet. 44, 426-429 (2012).
    • (2012) Nat. Genet. , vol.44 , pp. 426-429
    • Akamatsu, S.1
  • 14
    • 77956637724 scopus 로고    scopus 로고
    • Genome-wide association study identifes fve new susceptibility loci for prostate cancer in the Japanese population
    • Takata, R. et al. Genome-wide association study identifes fve new susceptibility loci for prostate cancer in the Japanese population. Nat. Genet. 42, 751-754 (2010).
    • (2010) Nat. Genet. , vol.42 , pp. 751-754
    • Takata, R.1
  • 15
    • 58249121582 scopus 로고    scopus 로고
    • Sequence variants at 22q13 are associated with prostate cancer risk
    • Sun, J. et al. Sequence variants at 22q13 are associated with prostate cancer risk. Cancer Res. 69, 10-15 (2009).
    • (2009) Cancer Res. , vol.69 , pp. 10-15
    • Sun, J.1
  • 16
    • 0036882394 scopus 로고    scopus 로고
    • Serine protease mechanism and specifcity
    • Hedstrom, L. Serine protease mechanism and specifcity. Chem. Rev. 102, 4501-4524 (2002).
    • (2002) Chem. Rev. , vol.102 , pp. 4501-4524
    • Hedstrom, L.1
  • 17
    • 47649121363 scopus 로고    scopus 로고
    • The discovery and application of gene fusions in prostate cancer
    • Morris, D.S., Tomlins, S.A., Montie, J.E. & Chinnaiyan, A.M. The discovery and application of gene fusions in prostate cancer. BJU Int. 102, 276-282 (2008).
    • (2008) BJU Int. , vol.102 , pp. 276-282
    • Morris, D.S.1    Tomlins, S.A.2    Montie, J.E.3    Chinnaiyan, A.M.4
  • 18
    • 68149100807 scopus 로고    scopus 로고
    • Genome-wide association study identifes variants at 9p21 and 22q13 associated with development of cutaneous nevi
    • Falchi, M. et al. Genome-wide association study identifes variants at 9p21 and 22q13 associated with development of cutaneous nevi. Nat. Genet. 41, 915-919 (2009).
    • (2009) Nat. Genet. , vol.41 , pp. 915-919
    • Falchi, M.1
  • 19
    • 0028100903 scopus 로고
    • Germline p16 mutations in familial melanoma
    • Hussussian, C.J. et al. Germline p16 mutations in familial melanoma. Nat. Genet. 8, 15-21 (1994).
    • (1994) Nat. Genet. , vol.8 , pp. 15-21
    • Hussussian, C.J.1
  • 20
    • 68149180890 scopus 로고    scopus 로고
    • Genome-wide association study identifes fve susceptibility loci for glioma
    • Shete, S. et al. Genome-wide association study identifes fve susceptibility loci for glioma. Nat. Genet. 41, 899-904 (2009).
    • (2009) Nat. Genet. , vol.41 , pp. 899-904
    • Shete, S.1
  • 21
    • 68149170036 scopus 로고    scopus 로고
    • New common variants affecting susceptibility to basal cell carcinoma
    • Stacey, S.N. et al. New common variants affecting susceptibility to basal cell carcinoma. Nat. Genet. 41, 909-914 (2009).
    • (2009) Nat. Genet. , vol.41 , pp. 909-914
    • Stacey, S.N.1
  • 22
    • 77952887426 scopus 로고    scopus 로고
    • Genome-wide association study identifes fve new breast cancer susceptibility loci
    • Turnbull, C. et al. Genome-wide association study identifes fve new breast cancer susceptibility loci. Nat. Genet. 42, 504-507 (2010).
    • (2010) Nat. Genet. , vol.42 , pp. 504-507
    • Turnbull, C.1
  • 23
    • 68149180891 scopus 로고    scopus 로고
    • Variants in the CDKN2B and RTEL1 regions are associated with high-grade glioma susceptibility
    • Wrensch, M. et al. Variants in the CDKN2B and RTEL1 regions are associated with high-grade glioma susceptibility. Nat. Genet. 41, 905-908 (2009).
    • (2009) Nat. Genet. , vol.41 , pp. 905-908
    • Wrensch, M.1
  • 24
    • 84868156549 scopus 로고    scopus 로고
    • Infuence of common genetic variation on lung cancer risk: Meta-analysis of 14 900 cases and 29 485 controls
    • Timofeeva, M.N. et al. Infuence of common genetic variation on lung cancer risk: meta-analysis of 14 900 cases and 29 485 controls. Hum. Mol. Genet. 21, 4980-4995 (2012).
    • (2012) Hum. Mol. Genet. , vol.21 , pp. 4980-4995
    • Timofeeva, M.N.1
  • 25
    • 77950605242 scopus 로고    scopus 로고
    • CAS proteins in normal and pathological cell growth control
    • Tikhmyanova, N., Little, J.L. & Golemis, E.A. CAS proteins in normal and pathological cell growth control. Cell. Mol. Life Sci. 67, 1025-1048 (2010).
    • (2010) Cell. Mol. Life Sci. , vol.67 , pp. 1025-1048
    • Tikhmyanova, N.1    Little, J.L.2    Golemis, E.A.3
  • 26
    • 70449381178 scopus 로고    scopus 로고
    • Myosin VI is a modulator of androgen-dependent gene expression
    • Loikkanen, I. et al. Myosin VI is a modulator of androgen-dependent gene expression. Oncol. Rep. 22, 991-995 (2009).
    • (2009) Oncol. Rep. , vol.22 , pp. 991-995
    • Loikkanen, I.1
  • 27
    • 74449085968 scopus 로고    scopus 로고
    • Overexpression of myosin VI in prostate cancer cells enhances PSA and VEGF secretion, but has no effect on endocytosis
    • Puri, C. et al. Overexpression of myosin VI in prostate cancer cells enhances PSA and VEGF secretion, but has no effect on endocytosis. Oncogene 29, 188-200 (2010).
    • (2010) Oncogene , vol.29 , pp. 188-200
    • Puri, C.1
  • 28
    • 50949101502 scopus 로고    scopus 로고
    • GOLPH2 and MYO6: Putative prostate cancer markers localized to the Golgi apparatus
    • Wei, S., Dunn, T.A., Isaacs, W.B., De Marzo, A.M. & Luo, J. GOLPH2 and MYO6: putative prostate cancer markers localized to the Golgi apparatus. Prostate 68, 1387-1395 (2008).
    • (2008) Prostate , vol.68 , pp. 1387-1395
    • Wei, S.1    Dunn, T.A.2    Isaacs, W.B.3    De Marzo, A.M.4    Luo, J.5
  • 29
    • 84875703379 scopus 로고    scopus 로고
    • Large-scale genotyping identifes 41 new loci associated with breast cancer risk
    • Michailidou, K. et al. Large-scale genotyping identifes 41 new loci associated with breast cancer risk. Nat. Genet. 45, 353-361 (2013).
    • (2013) Nat. Genet. , vol.45 , pp. 353-361
    • Michailidou, K.1
  • 30
    • 67651222400 scopus 로고    scopus 로고
    • A fexible and accurate genotype imputation method for the next generation of genome-wide association studies
    • Howie, B.N., Donnelly, P. & Marchini, J. A fexible and accurate genotype imputation method for the next generation of genome-wide association studies. PLoS Genet. 5, e1000529 (2009).
    • (2009) PLoS Genet. , vol.5 , pp. e1000529
    • Howie, B.N.1    Donnelly, P.2    Marchini, J.3
  • 31
    • 77951152163 scopus 로고    scopus 로고
    • ProbABEL package for genome-wide association analysis of imputed data
    • Aulchenko, Y.S., Struchalin, M.V. & van Duijn, C.M. ProbABEL package for genome-wide association analysis of imputed data. BMC Bioinformatics 11, 134 (2010).
    • (2010) BMC Bioinformatics , vol.11 , pp. 134
    • Aulchenko, Y.S.1    Struchalin, M.V.2    Van Duijn, C.M.3
  • 32
    • 77955894071 scopus 로고    scopus 로고
    • Fast and effcient meta-analysis of genomewide association scans
    • Willer, C.J., Li, Y. & Abecasis, G.R. METAL: fast and effcient meta-analysis of genomewide association scans. Bioinformatics 26, 2190-2191 (2010).
    • (2010) Bioinformatics , vol.26 , pp. 2190-2191
    • Willer, C.J.1    Li, Y.2
  • 33
    • 84896695503 scopus 로고    scopus 로고
    • Comprehensive functional annotation of 77 prostate cancer risk loci
    • Hazelett, D.J. et al. Comprehensive functional annotation of 77 prostate cancer risk loci. PLoS Genet. 10, e1004102 (2014).
    • (2014) PLoS Genet. , vol.10 , pp. e1004102
    • Hazelett, D.J.1
  • 34
    • 84865755978 scopus 로고    scopus 로고
    • The accessible chromatin landscape of the human genome
    • Thurman, R.E. et al. The accessible chromatin landscape of the human genome. Nature 489, 75-82 (2012).
    • (2012) Nature , vol.489 , pp. 75-82
    • Thurman, R.E.1
  • 35
    • 84867562866 scopus 로고    scopus 로고
    • FunciSNP: An R/bioconductor tool integrating functional non-coding data sets with genetic association studies to identify candidate regulatory SNPs
    • Coetzee, S.G., Rhie, S.K., Berman, B.P., Coetzee, G.A. & Noushmehr, H. FunciSNP: an R/bioconductor tool integrating functional non-coding data sets with genetic association studies to identify candidate regulatory SNPs. Nucleic Acids Res. 40, e139 (2012).
    • (2012) Nucleic Acids Res. , vol.40 , pp. e139
    • Coetzee, S.G.1    Rhie, S.K.2    Berman, B.P.3    Coetzee, G.A.4    Noushmehr, H.5
  • 36
    • 79959198166 scopus 로고    scopus 로고
    • Reprogramming transcription by distinct classes of enhancers functionally defned by eRNA
    • Wang, D. et al. Reprogramming transcription by distinct classes of enhancers functionally defned by eRNA. Nature 474, 390-394 (2011).
    • (2011) Nature , vol.474 , pp. 390-394
    • Wang, D.1
  • 37
    • 84863072810 scopus 로고    scopus 로고
    • Integration of regulatory networks by NKX3-1 promotes androgen-dependent prostate cancer survival
    • Tan, P.Y. et al. Integration of regulatory networks by NKX3-1 promotes androgen-dependent prostate cancer survival. Mol. Cell. Biol. 32, 399-414 (2012).
    • (2012) Mol. Cell. Biol. , vol.32 , pp. 399-414
    • Tan, P.Y.1
  • 38
    • 83255192190 scopus 로고    scopus 로고
    • Dynamic nucleosome-depleted regions at androgen receptor enhancers in the absence of ligand in prostate cancer cells
    • Andreu-Vieyra, C. et al. Dynamic nucleosome-depleted regions at androgen receptor enhancers in the absence of ligand in prostate cancer cells. Mol. Cell. Biol. 31, 4648-4662 (2011).
    • (2011) Mol. Cell. Biol. , vol.31 , pp. 4648-4662
    • Andreu-Vieyra, C.1
  • 39
    • 84872391385 scopus 로고    scopus 로고
    • The androgen receptor induces a distinct transcriptional program in castration-resistant prostate cancer in man
    • Sharma, N.L. et al. The androgen receptor induces a distinct transcriptional program in castration-resistant prostate cancer in man. Cancer Cell 23, 35-47 (2013).
    • (2013) Cancer Cell , vol.23 , pp. 35-47
    • Sharma, N.L.1
  • 40
    • 84865138690 scopus 로고    scopus 로고
    • MiRcode: A map of putative microRNA target sites in the long non-coding transcriptome
    • Jeggari, A., Marks, D.S. & Larsson, E. miRcode: a map of putative microRNA target sites in the long non-coding transcriptome. Bioinformatics 28, 2062-2063 (2012).
    • (2012) Bioinformatics , vol.28 , pp. 2062-2063
    • Jeggari, A.1    Marks, D.S.2    Larsson, E.3
  • 41
    • 84865852567 scopus 로고    scopus 로고
    • Sequence features and chromatin structure around the genomic regions bound by 119 human transcription factors
    • Wang, J. et al. Sequence features and chromatin structure around the genomic regions bound by 119 human transcription factors. Genome Res. 22, 1798-1812 (2012).
    • (2012) Genome Res. , vol.22 , pp. 1798-1812
    • Wang, J.1
  • 42
    • 84873288058 scopus 로고    scopus 로고
    • Integrative eQTL-based analyses reveal the biology of breast cancer risk loci
    • Li, Q. et al. Integrative eQTL-based analyses reveal the biology of breast cancer risk loci. Cell 152, 633-641 (2013).
    • (2013) Cell , vol.152 , pp. 633-641
    • Li, Q.1
  • 43
    • 0024406369 scopus 로고
    • Final report on the aspirin component of the ongoing Physicians' Health Study. Steering Committee of the Physicians' Health Study Research Group
    • Physicians' Health Study Research Group. Final report on the aspirin component of the ongoing Physicians' Health Study. Steering Committee of the Physicians' Health Study Research Group. N. Engl. J. Med. 321, 129-135 (1989).
    • (1989) N. Engl. J. Med. , vol.321 , pp. 129-135
  • 44
    • 12344280017 scopus 로고    scopus 로고
    • Summaries of Affymetrix GeneChip probe level data
    • Irizarry, R.A. et al. Summaries of Affymetrix GeneChip probe level data. Nucleic Acids Res. 31, e15 (2003).
    • (2003) Nucleic Acids Res. , vol.31 , pp. e15
    • Irizarry, R.A.1
  • 45
    • 0142121516 scopus 로고    scopus 로고
    • Exploration, normalization, and summaries of high density oligonucleotide array probe level data
    • Irizarry, R.A. et al. Exploration, normalization, and summaries of high density oligonucleotide array probe level data. Biostatistics 4, 249-264 (2003).
    • (2003) Biostatistics , vol.4 , pp. 249-264
    • Irizarry, R.A.1
  • 46
    • 39449116893 scopus 로고    scopus 로고
    • Fluorescence and chromogenic in situ hybridization to detect genetic aberrations in formalin-fxed paraffn embedded material, including tissue microarrays
    • Summersgill, B., Clark, J. & Shipley, J. Fluorescence and chromogenic in situ hybridization to detect genetic aberrations in formalin-fxed paraffn embedded material, including tissue microarrays. Nat. Protoc. 3, 220-234 (2008).
    • (2008) Nat. Protoc. , vol.3 , pp. 220-234
    • Summersgill, B.1    Clark, J.2    Shipley, J.3
  • 47
    • 34447342868 scopus 로고    scopus 로고
    • TMPRSS2-ERG fusion prostate cancer: An early molecular event associated with invasion
    • Perner, S. et al. TMPRSS2-ERG fusion prostate cancer: an early molecular event associated with invasion. Am. J. Surg. Pathol. 31, 882-888 (2007).
    • (2007) Am. J. Surg. Pathol. , vol.31 , pp. 882-888
    • Perner, S.1
  • 48
    • 50349102353 scopus 로고    scopus 로고
    • TMPRSS2:ERG fusion identifes a subgroup of prostate cancers with a favorable prognosis
    • Saramäki, O.R. et al. TMPRSS2:ERG fusion identifes a subgroup of prostate cancers with a favorable prognosis. Clin. Cancer Res. 14, 3395-3400 (2008).
    • (2008) Clin. Cancer Res. , vol.14 , pp. 3395-3400
    • Saramäki, O.R.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.