메뉴 건너뛰기




Volumn 46, Issue 10, 2014, Pages 1072-1080

Mouse tetrad analysis provides insights into recombination mechanisms and hotspot evolutionary dynamics

Author keywords

[No Author keywords available]

Indexed keywords

HISTONE H3; LYSINE; HISTONE LYSINE METHYLTRANSFERASE; PRDM9 PROTEIN, MOUSE;

EID: 84922009351     PISSN: 10614036     EISSN: 15461718     Source Type: Journal    
DOI: 10.1038/ng.3068     Document Type: Article
Times cited : (84)

References (64)
  • 2
    • 0033368701 scopus 로고    scopus 로고
    • Meiotic chromosomes: Integrating structure and function
    • Zickler, D. & Kleckner, N. Meiotic chromosomes: integrating structure and function. Annu. Rev. Genet. 33, 603-754 (1999).
    • (1999) Annu. Rev. Genet. , vol.33 , pp. 603-754
    • Zickler, D.1    Kleckner, N.2
  • 3
    • 84888594733 scopus 로고    scopus 로고
    • Initiation of meiotic recombination: How and where? Conservation and specifcities among eukaryotes
    • de Massy, B. Initiation of meiotic recombination: how and where? Conservation and specifcities among eukaryotes. Annu. Rev. Genet. 47, 563-599 (2013).
    • (2013) Annu. Rev. Genet. , vol.47 , pp. 563-599
    • De Massy, B.1
  • 4
    • 0001968134 scopus 로고
    • On two types of spore germination, and on genetic segregations in Saccharomycetes demonstrated through single-spore culture
    • Winge, O. & Laustsen, O. On two types of spore germination, and on genetic segregations in Saccharomycetes demonstrated through single-spore culture. C. R. Trav. Lab. Carlsberg., Ser. Physiol. 22, 99-117 (1937).
    • (1937) C. R. Trav. Lab. Carlsberg., Ser. Physiol. , vol.22 , pp. 99-117
    • Winge, O.1    Laustsen, O.2
  • 6
    • 0020541955 scopus 로고
    • The double-strand-break repair model for recombination
    • Szostak, J.W., Orr-Weaver, T.L., Rothstein, R.J. & Stahl, F.W. The double-strand-break repair model for recombination. Cell 33, 25-35 (1983).
    • (1983) Cell , vol.33 , pp. 25-35
    • Szostak, J.W.1    Orr-Weaver, T.L.2    Rothstein, R.J.3    Stahl, F.W.4
  • 7
    • 0035854342 scopus 로고    scopus 로고
    • Differential timing and control of noncrossover and crossover recombination during meiosis
    • Allers, T. & Lichten, M. Differential timing and control of noncrossover and crossover recombination during meiosis. Cell 106, 47-57 (2001).
    • (2001) Cell , vol.106 , pp. 47-57
    • Allers, T.1    Lichten, M.2
  • 8
    • 4344582144 scopus 로고    scopus 로고
    • Crossover/noncrossover differentiation, synaptonemal complex formation, and regulatory surveillance at the leptotene/zygotene transition of meiosis
    • Börner, G.V., Kleckner, N. & Hunter, N. Crossover/noncrossover differentiation, synaptonemal complex formation, and regulatory surveillance at the leptotene/zygotene transition of meiosis. Cell 117, 29-45 (2004).
    • (2004) Cell , vol.117 , pp. 29-45
    • Börner, G.V.1    Kleckner, N.2    Hunter, N.3
  • 9
    • 0035854362 scopus 로고    scopus 로고
    • The single-end invasion: An asymmetric intermediate at the double-strand break to double-Holliday junction transition of meiotic recombination
    • Hunter, N. & Kleckner, N. The single-end invasion: an asymmetric intermediate at the double-strand break to double-Holliday junction transition of meiotic recombination. Cell 106, 59-70 (2001).
    • (2001) Cell , vol.106 , pp. 59-70
    • Hunter, N.1    Kleckner, N.2
  • 10
    • 80053451692 scopus 로고    scopus 로고
    • Genome-wide analysis of heteroduplex DNA in mismatch repair-defcient yeast cells reveals novel properties of meiotic recombination pathways
    • Martini, E. et al. Genome-wide analysis of heteroduplex DNA in mismatch repair-defcient yeast cells reveals novel properties of meiotic recombination pathways. PLoS Genet. 7, e1002305 (2011).
    • (2011) PLoS Genet. , vol.7 , pp. e1002305
    • Martini, E.1
  • 11
    • 37249083430 scopus 로고    scopus 로고
    • Synthesis-dependent strand annealing in meiosis
    • McMahill, M.S., Sham, C.W. & Bishop, D.K. Synthesis-dependent strand annealing in meiosis. PLoS Biol. 5, e299 (2007).
    • (2007) PLoS Biol. , vol.5 , pp. e299
    • McMahill, M.S.1    Sham, C.W.2    Bishop, D.K.3
  • 13
    • 84886035850 scopus 로고    scopus 로고
    • Meiotic recombination in mammals: Localization and regulation
    • Baudat, F., Imai, Y. & de Massy, B. Meiotic recombination in mammals: localization and regulation. Nat. Rev. Genet. 14, 794-806 (2013).
    • (2013) Nat. Rev. Genet. , vol.14 , pp. 794-806
    • Baudat, F.1    Imai, Y.2    De Massy, B.3
  • 14
    • 77249144000 scopus 로고    scopus 로고
    • Mammalian recombination hot spots: Properties, control and evolution
    • Paigen, K. & Petkov, P. Mammalian recombination hot spots: properties, control and evolution. Nat. Rev. Genet. 11, 221-233 (2010).
    • (2010) Nat. Rev. Genet. , vol.11 , pp. 221-233
    • Paigen, K.1    Petkov, P.2
  • 15
    • 84893594630 scopus 로고    scopus 로고
    • Genome analyses of single human oocytes
    • Hou, Y. et al. Genome analyses of single human oocytes. Cell 155, 1492-1506 (2013).
    • (2013) Cell , vol.155 , pp. 1492-1506
    • Hou, Y.1
  • 16
    • 84871447495 scopus 로고    scopus 로고
    • Probing meiotic recombination and aneuploidy of single sperm cells by whole-genome sequencing
    • Lu, S. et al. Probing meiotic recombination and aneuploidy of single sperm cells by whole-genome sequencing. Science 338, 1627-1630 (2012).
    • (2012) Science , vol.338 , pp. 1627-1630
    • Lu, S.1
  • 17
    • 84864258558 scopus 로고    scopus 로고
    • Genome-wide single-cell analysis of recombination activity and de novo mutation rates in human sperm
    • Wang, J., Fan, H.C., Behr, B. & Quake, S.R. Genome-wide single-cell analysis of recombination activity and de novo mutation rates in human sperm. Cell 150, 402-412 (2012).
    • (2012) Cell , vol.150 , pp. 402-412
    • Wang, J.1    Fan, H.C.2    Behr, B.3    Quake, S.R.4
  • 18
    • 77956536176 scopus 로고    scopus 로고
    • Comprehensive fne-scale dissection of homologous recombination outcomes at a hot spot in mouse meiosis
    • Cole, F., Keeney, S. & Jasin, M. Comprehensive, fne-scale dissection of homologous recombination outcomes at a hot spot in mouse meiosis. Mol. Cell 39, 700-710 (2010).
    • (2010) Mol. Cell , vol.39 , pp. 700-710
    • Cole, F.1    Keeney, S.2    Jasin, M.3
  • 19
  • 20
    • 0036787813 scopus 로고    scopus 로고
    • An initiation site for meiotic crossing-over and gene conversion in the mouse
    • Guillon, H. & de Massy, B. An initiation site for meiotic crossing-over and gene conversion in the mouse. Nat. Genet. 32, 296-299 (2002).
    • (2002) Nat. Genet. , vol.32 , pp. 296-299
    • Guillon, H.1    De Massy, B.2
  • 21
    • 0842310835 scopus 로고    scopus 로고
    • Intense and highly localized gene conversion activity in human meiotic crossover hot spots
    • Jeffreys, A.J. & May, C.A. Intense and highly localized gene conversion activity in human meiotic crossover hot spots. Nat. Genet. 36, 151-156 (2004).
    • (2004) Nat. Genet. , vol.36 , pp. 151-156
    • Jeffreys, A.J.1    May, C.A.2
  • 22
    • 51649083682 scopus 로고    scopus 로고
    • A quantitative assay for crossover and noncrossover molecular events at individual recombination hotspots in both male and female gametes
    • Ng, S.H., Parvanov, E., Petkov, P.M. & Paigen, K. A quantitative assay for crossover and noncrossover molecular events at individual recombination hotspots in both male and female gametes. Genomics 92, 204-209 (2008).
    • (2008) Genomics , vol.92 , pp. 204-209
    • Ng, S.H.1    Parvanov, E.2    Petkov, P.M.3    Paigen, K.4
  • 23
    • 34347352200 scopus 로고    scopus 로고
    • Cis-and trans-acting elements regulate the mouse Psmb9 meiotic recombination hotspot
    • Baudat, F. & de Massy, B. Cis-and trans-acting elements regulate the mouse Psmb9 meiotic recombination hotspot. PLoS Genet. 3, e100 (2007).
    • (2007) PLoS Genet. , vol.3 , pp. e100
    • Baudat, F.1    De Massy, B.2
  • 24
    • 34648877413 scopus 로고    scopus 로고
    • (eds. Egel, R. & Lankenau, D.-H.) Springer-Verlag, Berlin and Heidelberg, Germany
    • Keeney, S. in Recombination and Meiosis (eds. Egel, R. & Lankenau, D.-H.) 81-123 (Springer-Verlag, Berlin and Heidelberg, Germany, 2007).
    • (2007) Recombination and Meiosis , pp. 81-123
    • Keeney, S.1
  • 25
    • 77953925453 scopus 로고    scopus 로고
    • Evolutionary conservation of meiotic DSB proteins: More than just Spo11
    • Cole, F., Keeney, S. & Jasin, M. Evolutionary conservation of meiotic DSB proteins: more than just Spo11. Genes Dev. 24, 1201-1207 (2010).
    • (2010) Genes Dev. , vol.24 , pp. 1201-1207
    • Cole, F.1    Keeney, S.2    Jasin, M.3
  • 26
    • 3042742130 scopus 로고    scopus 로고
    • Where the crossovers are: Recombination distributions in mammals
    • Kauppi, L., Jeffreys, A.J. & Keeney, S. Where the crossovers are: recombination distributions in mammals. Nat. Rev. Genet. 5, 413-424 (2004).
    • (2004) Nat. Rev. Genet. , vol.5 , pp. 413-424
    • Kauppi, L.1    Jeffreys, A.J.2    Keeney, S.3
  • 27
    • 76749170346 scopus 로고    scopus 로고
    • PRDM9 is a major determinant of meiotic recombination hotspots in humans and mice
    • Baudat, F. et al. PRDM9 is a major determinant of meiotic recombination hotspots in humans and mice. Science 327, 836-840 (2010).
    • (2010) Science , vol.327 , pp. 836-840
    • Baudat, F.1
  • 28
    • 84863770992 scopus 로고    scopus 로고
    • Genetic recombination is directed away from functional genomic elements in mice
    • Brick, K., Smagulova, F., Khil, P., Camerini-Otero, R.D. & Petukhova, G.V. Genetic recombination is directed away from functional genomic elements in mice. Nature 485, 642-645 (2012).
    • (2012) Nature , vol.485 , pp. 642-645
    • Brick, K.1    Smagulova, F.2    Khil, P.3    Camerini-Otero, R.D.4    Petukhova, G.V.5
  • 29
    • 76749155072 scopus 로고    scopus 로고
    • Drive against hotspot motifs in primates implicates the PRDM9 gene in meiotic recombination
    • Myers, S. et al. Drive against hotspot motifs in primates implicates the PRDM9 gene in meiotic recombination. Science 327, 876-879 (2010).
    • (2010) Science , vol.327 , pp. 876-879
    • Myers, S.1
  • 30
    • 76749151934 scopus 로고    scopus 로고
    • Prdm9 controls activation of mammalian recombination hotspots
    • Parvanov, E.D., Petkov, P.M. & Paigen, K. Prdm9 controls activation of mammalian recombination hotspots. Science 327, 835 (2010).
    • (2010) Science , vol.327 , pp. 835
    • Parvanov, E.D.1    Petkov, P.M.2    Paigen, K.3
  • 31
    • 84876672046 scopus 로고    scopus 로고
    • DNA binding specifcities of the long zinc-fnger recombination protein PRDM9
    • Billings, T. et al. DNA binding specifcities of the long zinc-fnger recombination protein PRDM9. Genome Biol. 14, R35 (2013).
    • (2013) Genome Biol. , vol.14 , pp. R35
    • Billings, T.1
  • 32
    • 80055056367 scopus 로고    scopus 로고
    • Mouse PRDM9 DNA-binding specifcity determines sites of histone H3 lysine 4 trimethylation for initiation of meiotic recombination
    • Grey, C. et al. Mouse PRDM9 DNA-binding specifcity determines sites of histone H3 lysine 4 trimethylation for initiation of meiotic recombination. PLoS Biol. 9, e1001176 (2011).
    • (2011) PLoS Biol. , vol.9 , pp. e1001176
    • Grey, C.1
  • 33
    • 0036649022 scopus 로고    scopus 로고
    • Reciprocal crossover asymmetry and meiotic drive in a human recombination hot spot
    • Jeffreys, A.J. & Neumann, R. Reciprocal crossover asymmetry and meiotic drive in a human recombination hot spot. Nat. Genet. 31, 267-271 (2002).
    • (2002) Nat. Genet. , vol.31 , pp. 267-271
    • Jeffreys, A.J.1    Neumann, R.2
  • 34
    • 69849115535 scopus 로고    scopus 로고
    • Distinct histone modifcations defne initiation and repair of meiotic recombination in the mouse
    • Buard, J., Barthes, P., Grey, C. & de Massy, B. Distinct histone modifcations defne initiation and repair of meiotic recombination in the mouse. EMBO J. 28, 2616-2624 (2009).
    • (2009) EMBO J. , vol.28 , pp. 2616-2624
    • Buard, J.1    Barthes, P.2    Grey, C.3    De Massy, B.4
  • 35
    • 18044393203 scopus 로고    scopus 로고
    • Flow cytometric characterization of viable meiotic and postmeiotic cells by Hoechst 33342 in mouse spermatogenesis
    • Bastos, H. et al. Flow cytometric characterization of viable meiotic and postmeiotic cells by Hoechst 33342 in mouse spermatogenesis. Cytometry A 65, 40-49 (2005).
    • (2005) Cytometry A , vol.65 , pp. 40-49
    • Bastos, H.1
  • 36
    • 80053309149 scopus 로고    scopus 로고
    • Isolation of meiotic recombinants from mouse sperm
    • Cole, F. & Jasin, M. Isolation of meiotic recombinants from mouse sperm. Methods Mol. Biol. 745, 251-282 (2011).
    • (2011) Methods Mol. Biol. , vol.745 , pp. 251-282
    • Cole, F.1    Jasin, M.2
  • 37
    • 8944232867 scopus 로고    scopus 로고
    • Involvement of mouse Mlh1 in DNA mismatch repair and meiotic crossing over
    • Baker, S.M. et al. Involvement of mouse Mlh1 in DNA mismatch repair and meiotic crossing over. Nat. Genet. 13, 336-342 (1996).
    • (1996) Nat. Genet. , vol.13 , pp. 336-342
    • Baker, S.M.1
  • 38
    • 0033612535 scopus 로고    scopus 로고
    • Chromosomal infuence on meiotic spindle assembly: Abnormal meiosis i in female Mlh1 mutant mice
    • Woods, L.M. et al. Chromosomal infuence on meiotic spindle assembly: abnormal meiosis I in female Mlh1 mutant mice. J. Cell Biol. 145, 1395-1406 (1999).
    • (1999) J. Cell Biol. , vol.145 , pp. 1395-1406
    • Woods, L.M.1
  • 39
    • 47949108144 scopus 로고    scopus 로고
    • High-resolution mapping of meiotic crossovers and non-crossovers in yeast
    • Mancera, E., Bourgon, R., Brozzi, A., Huber, W. & Steinmetz, L.M. High-resolution mapping of meiotic crossovers and non-crossovers in yeast. Nature 454, 479-485 (2008).
    • (2008) Nature , vol.454 , pp. 479-485
    • Mancera, E.1    Bourgon, R.2    Brozzi, A.3    Huber, W.4    Steinmetz, L.M.5
  • 40
    • 35148822185 scopus 로고    scopus 로고
    • A highly polymorphic meiotic recombination mouse hot spot exhibits incomplete repair
    • Bois, P.R. A highly polymorphic meiotic recombination mouse hot spot exhibits incomplete repair. Mol. Cell. Biol. 27, 7053-7062 (2007).
    • (2007) Mol. Cell. Biol. , vol.27 , pp. 7053-7062
    • Bois, P.R.1
  • 41
    • 26444503776 scopus 로고    scopus 로고
    • Factors infuencing recombination frequency and distribution in a human meiotic crossover hotspot
    • Jeffreys, A.J. & Neumann, R. Factors infuencing recombination frequency and distribution in a human meiotic crossover hotspot. Hum. Mol. Genet. 14, 2277-2287 (2005).
    • (2005) Hum. Mol. Genet. , vol.14 , pp. 2277-2287
    • Jeffreys, A.J.1    Neumann, R.2
  • 42
    • 84901741920 scopus 로고    scopus 로고
    • Transmission distortion affecting human noncrossover but not crossover recombination: A hidden source of meiotic drive
    • Odenthal-Hesse, L., Berg, I.L., Veselis, A., Jeffreys, A.J. & May, C.A. Transmission distortion affecting human noncrossover but not crossover recombination: a hidden source of meiotic drive. PLoS Genet. 10, e1004106 (2014).
    • (2014) PLoS Genet. , vol.10 , pp. e1004106
    • Odenthal-Hesse, L.1    Berg, I.L.2    Veselis, A.3    Jeffreys, A.J.4    May, C.A.5
  • 43
    • 84859229732 scopus 로고    scopus 로고
    • A major recombination hotspot in the XqYq pseudoautosomal region gives new insight into processing of human gene conversion events
    • Sarbajna, S. et al. A major recombination hotspot in the XqYq pseudoautosomal region gives new insight into processing of human gene conversion events. Hum. Mol. Genet. 21, 2029-2038 (2012).
    • (2012) Hum. Mol. Genet. , vol.21 , pp. 2029-2038
    • Sarbajna, S.1
  • 44
    • 0037451351 scopus 로고    scopus 로고
    • High-resolution sperm typing of meiotic recombination in the mouse MHC Eβ gene
    • Yauk, C.L., Bois, P.R. & Jeffreys, A.J. High-resolution sperm typing of meiotic recombination in the mouse MHC Eβ gene. EMBO J. 22, 1389-1397 (2003).
    • (2003) EMBO J. , vol.22 , pp. 1389-1397
    • Yauk, C.L.1    Bois, P.R.2    Jeffreys, A.J.3
  • 45
    • 0347987856 scopus 로고    scopus 로고
    • The Bloom's syndrome helicase suppresses crossing over during homologous recombination
    • Wu, L. & Hickson, I.D. The Bloom's syndrome helicase suppresses crossing over during homologous recombination. Nature 426, 870-874 (2003).
    • (2003) Nature , vol.426 , pp. 870-874
    • Wu, L.1    Hickson, I.D.2
  • 46
    • 51449104284 scopus 로고    scopus 로고
    • Global analysis of the meiotic crossover landscape
    • Chen, S.Y. et al. Global analysis of the meiotic crossover landscape. Dev. Cell 15, 401-415 (2008).
    • (2008) Dev. Cell , vol.15 , pp. 401-415
    • Chen, S.Y.1
  • 47
    • 84876893983 scopus 로고    scopus 로고
    • Numerical constraints and feedback control of double-strand breaks in mouse meiosis
    • Kauppi, L. et al. Numerical constraints and feedback control of double-strand breaks in mouse meiosis. Genes Dev. 27, 873-886 (2013).
    • (2013) Genes Dev. , vol.27 , pp. 873-886
    • Kauppi, L.1
  • 48
    • 84899837850 scopus 로고    scopus 로고
    • PRDM9 binding organizes hotspot nucleosomes and limits Holliday junction migration
    • Baker, C.L., Walker, M., Kajita, S., Petkov, P.M. & Paigen, K. PRDM9 binding organizes hotspot nucleosomes and limits Holliday junction migration. Genome Res. 24, 724-732 (2014).
    • (2014) Genome Res. , vol.24 , pp. 724-732
    • Baker, C.L.1    Walker, M.2    Kajita, S.3    Petkov, P.M.4    Paigen, K.5
  • 49
    • 79952295560 scopus 로고    scopus 로고
    • A hierarchical combination of factors shapes the genome-wide topography of yeast meiotic recombination initiation
    • Pan, J. et al. A hierarchical combination of factors shapes the genome-wide topography of yeast meiotic recombination initiation. Cell 144, 719-731 (2011).
    • (2011) Cell , vol.144 , pp. 719-731
    • Pan, J.1
  • 50
    • 34548553001 scopus 로고    scopus 로고
    • Meiotic recombination in Drosophila Msh6 mutants yields discontinuous gene conversion tracts
    • Radford, S.J., Sabourin, M.M., McMahan, S. & Sekelsky, J. Meiotic recombination in Drosophila Msh6 mutants yields discontinuous gene conversion tracts. Genetics 176, 53-62 (2007).
    • (2007) Genetics , vol.176 , pp. 53-62
    • Radford, S.J.1    Sabourin, M.M.2    McMahan, S.3    Sekelsky, J.4
  • 51
    • 34447536139 scopus 로고    scopus 로고
    • BLM ortholog, Sgs1, prevents aberrant crossing-over by suppressing formation of multichromatid joint molecules
    • Oh, S.D. et al. BLM ortholog, Sgs1, prevents aberrant crossing-over by suppressing formation of multichromatid joint molecules. Cell 130, 259-272 (2007).
    • (2007) Cell , vol.130 , pp. 259-272
    • Oh, S.D.1
  • 52
    • 48349139797 scopus 로고    scopus 로고
    • RecQ helicase, Sgs1, and XPF family endonuclease, Mus81-Mms4, resolve aberrant joint molecules during meiotic recombination
    • Oh, S.D., Lao, J.P., Taylor, A.F., Smith, G.R. & Hunter, N. RecQ helicase, Sgs1, and XPF family endonuclease, Mus81-Mms4, resolve aberrant joint molecules during meiotic recombination. Mol. Cell 31, 324-336 (2008).
    • (2008) Mol. Cell , vol.31 , pp. 324-336
    • Oh, S.D.1    Lao, J.P.2    Taylor, A.F.3    Smith, G.R.4    Hunter, N.5
  • 53
    • 78149401426 scopus 로고    scopus 로고
    • Frequent and effcient use of the sister chromatid for DNA double-strand break repair during budding yeast meiosis
    • Goldfarb, T. & Lichten, M. Frequent and effcient use of the sister chromatid for DNA double-strand break repair during budding yeast meiosis. PLoS Biol. 8, e1000520 (2010).
    • (2010) PLoS Biol. , vol.8 , pp. e1000520
    • Goldfarb, T.1    Lichten, M.2
  • 54
    • 0030791317 scopus 로고    scopus 로고
    • The hotspot conversion paradox and the evolution of meiotic recombination
    • Boulton, A., Myers, R.S. & Redfeld, R.J. The hotspot conversion paradox and the evolution of meiotic recombination. Proc. Natl. Acad. Sci. USA 94, 8058-8063 (1997).
    • (1997) Proc. Natl. Acad. Sci. USA , vol.94 , pp. 8058-8063
    • Boulton, A.1    Myers, R.S.2    Redfeld, R.J.3
  • 55
    • 34047200066 scopus 로고    scopus 로고
    • Live hot, die young: Transmission distortion in recombination hotspots
    • Coop, G. & Myers, S.R. Live hot, die young: transmission distortion in recombination hotspots. PLoS Genet. 3, e35 (2007).
    • (2007) PLoS Genet. , vol.3 , pp. e35
    • Coop, G.1    Myers, S.R.2
  • 56
    • 34248364837 scopus 로고    scopus 로고
    • A population genetics model with recombination hotspots that are heterogeneous across the population
    • Calabrese, P. A population genetics model with recombination hotspots that are heterogeneous across the population. Proc. Natl. Acad. Sci. USA 104, 4748-4752 (2007).
    • (2007) Proc. Natl. Acad. Sci. USA , vol.104 , pp. 4748-4752
    • Calabrese, P.1
  • 57
    • 18844419731 scopus 로고    scopus 로고
    • Persistence and loss of meiotic recombination hotspots
    • Pineda-Krch, M. & Redfeld, R.J. Persistence and loss of meiotic recombination hotspots. Genetics 169, 2319-2333 (2005).
    • (2005) Genetics , vol.169 , pp. 2319-2333
    • Pineda-Krch, M.1    Redfeld, R.J.2
  • 58
    • 0032918559 scopus 로고    scopus 로고
    • Distribution of crossing over on mouse synaptonemal complexes using immunofuorescent localization of MLH1 protein
    • Anderson, L.K., Reeves, A., Webb, L.M. & Ashley, T. Distribution of crossing over on mouse synaptonemal complexes using immunofuorescent localization of MLH1 protein. Genetics 151, 1569-1579 (1999).
    • (1999) Genetics , vol.151 , pp. 1569-1579
    • Anderson, L.K.1    Reeves, A.2    Webb, L.M.3    Ashley, T.4
  • 59
    • 84862777638 scopus 로고    scopus 로고
    • Homeostatic control of recombination is implemented progressively in mouse meiosis
    • Cole, F. et al. Homeostatic control of recombination is implemented progressively in mouse meiosis. Nat. Cell Biol. 14, 424-430 (2012).
    • (2012) Nat. Cell Biol. , vol.14 , pp. 424-430
    • Cole, F.1
  • 60
    • 0025974980 scopus 로고
    • Genetic control of sex-dependent meiotic recombination in the major histocompatibility complex of the mouse
    • Shiroishi, T., Sagai, T., Hanzawa, N., Gotoh, H. & Moriwaki, K. Genetic control of sex-dependent meiotic recombination in the major histocompatibility complex of the mouse. EMBO J. 10, 681-686 (1991).
    • (1991) EMBO J. , vol.10 , pp. 681-686
    • Shiroishi, T.1    Sagai, T.2    Hanzawa, N.3    Gotoh, H.4    Moriwaki, K.5
  • 61
    • 0030773638 scopus 로고    scopus 로고
    • Molecular analysis of gene conversion in spermatids from transgenic mice
    • Hanneman, W.H., Schimenti, K.J. & Schimenti, J.C. Molecular analysis of gene conversion in spermatids from transgenic mice. Gene 200, 185-192 (1997).
    • (1997) Gene , vol.200 , pp. 185-192
    • Hanneman, W.H.1    Schimenti, K.J.2    Schimenti, J.C.3
  • 62
    • 0025141652 scopus 로고
    • Repeat unit sequence variation in minisatellites: A novel source of DNA polymorphism for studying variation and mutation by single molecule analysis
    • Jeffreys, A.J., Neumann, R. & Wilson, V. Repeat unit sequence variation in minisatellites: a novel source of DNA polymorphism for studying variation and mutation by single molecule analysis. Cell 60, 473-485 (1990).
    • (1990) Cell , vol.60 , pp. 473-485
    • Jeffreys, A.J.1    Neumann, R.2    Wilson, V.3
  • 63
    • 0027965145 scopus 로고
    • A fow cytometric method using Hoechst 33342 and propidium iodide for simultaneous cell cycle analysis and apoptosis determination in unfxed cells
    • Belloc, F. et al. A fow cytometric method using Hoechst 33342 and propidium iodide for simultaneous cell cycle analysis and apoptosis determination in unfxed cells. Cytometry 17, 59-65 (1994).
    • (1994) Cytometry , vol.17 , pp. 59-65
    • Belloc, F.1
  • 64
    • 44949130714 scopus 로고    scopus 로고
    • ATM promotes the obligate XY crossover and both crossover control and chromosome axis integrity on autosomes
    • Barchi, M. et al. ATM promotes the obligate XY crossover and both crossover control and chromosome axis integrity on autosomes. PLoS Genet. 4, e1000076 (2008).
    • (2008) PLoS Genet. , vol.4 , pp. e1000076
    • Barchi, M.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.