메뉴 건너뛰기




Volumn 109, Issue , 2015, Pages 1-6

Construction, expression, purification, and characterization of a dual-targeting PD-1/VEGF-A fusion protein (P-V)

Author keywords

293E cells; Anti tumor; Dual targeting; Fusion protein; PD 1; VEGF A

Indexed keywords

HYBRID PROTEIN; PROGRAMMED DEATH 1 RECEPTOR; VASCULOTROPIN A;

EID: 84921992476     PISSN: 10465928     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.pep.2015.01.004     Document Type: Article
Times cited : (1)

References (30)
  • 1
    • 0026700235 scopus 로고
    • Induced expression of PD-1, a novel member of the immunoglobulin gene superfamily, upon programmed cell death
    • Y. Ishida, Y. Agata, K. Shibahara, T. Honjo, Induced expression of PD-1, a novel member of the immunoglobulin gene superfamily, upon programmed cell death, EMBO J. 11 (1992) 3887-3895.
    • (1992) EMBO J. , vol.11 , pp. 3887-3895
    • Ishida, Y.1    Agata, Y.2    Shibahara, K.3    Honjo, T.4
  • 3
    • 2442585121 scopus 로고    scopus 로고
    • Co-inhibitory molecules of the B7-CD28 family in the control of T-cell immunity
    • L. Chen, Co-inhibitory molecules of the B7-CD28 family in the control of T-cell immunity, Nat. Rev. Immunol. 4 (2004) 336-347.
    • (2004) Nat. Rev. Immunol. , vol.4 , pp. 336-347
    • Chen, L.1
  • 5
    • 84870945643 scopus 로고    scopus 로고
    • PD-1 inhibits T cell proliferation by upregulating p27 and p15 and suppressing Cdc25A
    • N. Patsoukis, D. Sari, V.A. Boussiotis, PD-1 inhibits T cell proliferation by upregulating p27 and p15 and suppressing Cdc25A, Cell Cycle 11 (2012) 4305-4309.
    • (2012) Cell Cycle , vol.11 , pp. 4305-4309
    • Patsoukis, N.1    Sari, D.2    Boussiotis, V.A.3
  • 7
    • 84874869077 scopus 로고    scopus 로고
    • Antagonist antibodies to PD-1 and B7-H1 (PD-L1) in the treatment of advanced human cancer
    • M. Sznol, L. Chen, Antagonist antibodies to PD-1 and B7-H1 (PD-L1) in the treatment of advanced human cancer, Clin. Cancer Res. 19 (2013) 1021-1034.
    • (2013) Clin. Cancer Res. , vol.19 , pp. 1021-1034
    • Sznol, M.1    Chen, L.2
  • 9
    • 77958012775 scopus 로고    scopus 로고
    • Gene signature in melanoma associated with clinical activity: A potential clue to unlock cancer immunotherapy
    • T.F. Gajewski, J. Louahed, V.G. Brichard, Gene signature in melanoma associated with clinical activity: a potential clue to unlock cancer immunotherapy, Cancer J. 16 (2010) 399-403.
    • (2010) Cancer J. , vol.16 , pp. 399-403
    • Gajewski, T.F.1    Louahed, J.2    Brichard, V.G.3
  • 10
    • 77957664158 scopus 로고    scopus 로고
    • Programmed death-1 upregulation is correlated with dysfunction of tumor-infiltrating CD8+ T lymphocytes in human non-small cell lung cancer
    • Y. Zhang, S. Huang, D. Gong, Y. Qin, Q. Shen, Programmed death-1 upregulation is correlated with dysfunction of tumor-infiltrating CD8+ T lymphocytes in human non-small cell lung cancer, Cell. Mol. Immunol. 7 (2010) 389-395.
    • (2010) Cell. Mol. Immunol. , vol.7 , pp. 389-395
    • Zhang, Y.1    Huang, S.2    Gong, D.3    Qin, Y.4    Shen, Q.5
  • 12
    • 0142149029 scopus 로고
    • Absence of programmed death receptor 1 alters thymic development and enhances generation of CD4/CD8 double-negative TCR-transgenic T cells
    • Baltimore, Md
    • C. Blank, I. Brown, R. Marks, H. Nishimura, T. Honjo, T.F. Gajewski, Absence of programmed death receptor 1 alters thymic development and enhances generation of CD4/CD8 double-negative TCR-transgenic T cells, J. Immunol. 171 (2003) 4574-4581 (Baltimore, Md: 1950).
    • (1950) J. Immunol. , vol.171 , pp. 4574-4581
    • Blank, C.1    Brown, I.2    Marks, R.3    Nishimura, H.4    Honjo, T.5    Gajewski, T.F.6
  • 13
    • 84881128700 scopus 로고    scopus 로고
    • Abstracts of the Society for Melanoma Research 2012 Congress. November 8-11, 2012. Hollywood, California, USA
    • Abstracts of the Society for Melanoma Research 2012 Congress. November 8-11, 2012. Hollywood, California, USA, Pigm. Cell Melanoma Res. 25 (2012) (2012) 836-903.
    • (2012) Pigm. Cell Melanoma Res. , vol.25 , Issue.2012 , pp. 836-903
  • 15
    • 85013312416 scopus 로고
    • Tumor angiogenesis: Therapeutic implications
    • J. Folkman, Tumor angiogenesis: therapeutic implications, N. Engl. J. Med. 285 (1971) 1182-1186.
    • (1971) N. Engl. J. Med. , vol.285 , pp. 1182-1186
    • Folkman, J.1
  • 17
    • 0027979253 scopus 로고
    • Homologs of vascular endothelial growth factor are encoded by the poxvirus orf virus
    • D.J. Lyttle, K.M. Fraser, S.B. Fleming, A.A. Mercer, A.J. Robinson, Homologs of vascular endothelial growth factor are encoded by the poxvirus orf virus, J. Virol. 68 (1994) 84-92.
    • (1994) J. Virol. , vol.68 , pp. 84-92
    • Lyttle, D.J.1    Fraser, K.M.2    Fleming, S.B.3    Mercer, A.A.4    Robinson, A.J.5
  • 18
    • 0036527585 scopus 로고    scopus 로고
    • Molecular mechanisms of lymphangiogenesis in health and disease
    • K. Alitalo, P. Carmeliet, Molecular mechanisms of lymphangiogenesis in health and disease, Cancer Cell 1 (2002) 219-227.
    • (2002) Cancer Cell , vol.1 , pp. 219-227
    • Alitalo, K.1    Carmeliet, P.2
  • 19
    • 0346101800 scopus 로고    scopus 로고
    • Snake venom vascular endothelial growth factors (VEGFs) exhibit potent activity through their specific recognition of KDR (VEGF receptor 2)
    • Y. Yamazaki, K. Takani, H. Atoda, T. Morita, Snake venom vascular endothelial growth factors (VEGFs) exhibit potent activity through their specific recognition of KDR (VEGF receptor 2), J. Biol. Chem. 278 (2003) 51985-51988.
    • (2003) J. Biol. Chem. , vol.278 , pp. 51985-51988
    • Yamazaki, Y.1    Takani, K.2    Atoda, H.3    Morita, T.4
  • 20
    • 8544262237 scopus 로고    scopus 로고
    • A novel snake venom vascular endothelial growth factor (VEGF) predominantly induces vascular permeability through preferential signaling via VEGF receptor-1
    • H. Takahashi, S. Hattori, A. Iwamatsu, H. Takizawa, M. Shibuya, A novel snake venom vascular endothelial growth factor (VEGF) predominantly induces vascular permeability through preferential signaling via VEGF receptor-1, J. Biol. Chem. 279 (2004) 46304-46314.
    • (2004) J. Biol. Chem. , vol.279 , pp. 46304-46314
    • Takahashi, H.1    Hattori, S.2    Iwamatsu, A.3    Takizawa, H.4    Shibuya, M.5
  • 21
    • 77954619947 scopus 로고    scopus 로고
    • Molecular and clinical aspects of targeting the VEGF pathway in tumors
    • G. Korpanty, L.A. Sullivan, E. Smyth, D.N. Carney, R.A. Brekken, Molecular and clinical aspects of targeting the VEGF pathway in tumors, J. Oncol. 2010 (2010) 652320.
    • (2010) J. Oncol. , vol.2010 , pp. 652320
    • Korpanty, G.1    Sullivan, L.A.2    Smyth, E.3    Carney, D.N.4    Brekken, R.A.5
  • 22
    • 0037699954 scopus 로고    scopus 로고
    • The biology of VEGF and its receptors
    • N. Ferrara, H.P. Gerber, J. LeCouter, The biology of VEGF and its receptors, Nat. Med. 9 (2003) 669-676.
    • (2003) Nat. Med. , vol.9 , pp. 669-676
    • Ferrara, N.1    Gerber, H.P.2    LeCouter, J.3
  • 23
    • 83255162010 scopus 로고    scopus 로고
    • Vascular endothelial growth factor (VEGF), VEGF receptors and their inhibitors for antiangiogenic tumor therapy
    • S. Takahashi, Vascular endothelial growth factor (VEGF), VEGF receptors and their inhibitors for antiangiogenic tumor therapy, Biol. Pharm. Bull. 34 (2011) 1785-1788.
    • (2011) Biol. Pharm. Bull. , vol.34 , pp. 1785-1788
    • Takahashi, S.1
  • 24
    • 0032080310 scopus 로고    scopus 로고
    • Requirements for binding and signaling of the kinase domain receptor for vascular endothelial growth factor
    • G. Fuh, B. Li, C. Crowley, B. Cunningham, J.A. Wells, Requirements for binding and signaling of the kinase domain receptor for vascular endothelial growth factor, J. Biol. Chem. 273 (1998) 11197-11204.
    • (1998) J. Biol. Chem. , vol.273 , pp. 11197-11204
    • Fuh, G.1    Li, B.2    Crowley, C.3    Cunningham, B.4    Wells, J.A.5
  • 26
    • 33947414473 scopus 로고    scopus 로고
    • VEGF-A and the induction of pathological angiogenesis
    • J.A. Nagy, A.M. Dvorak, H.F. Dvorak, VEGF-A and the induction of pathological angiogenesis, Ann. Rev. Pathol. 2 (2007) 251-275.
    • (2007) Ann. Rev. Pathol. , vol.2 , pp. 251-275
    • Nagy, J.A.1    Dvorak, A.M.2    Dvorak, H.F.3
  • 27
    • 84871633270 scopus 로고    scopus 로고
    • Vascular endothelial growth factor and its receptor system: Physiological functions in angiogenesis and pathological roles in various diseases
    • M. Shibuya, Vascular endothelial growth factor and its receptor system: physiological functions in angiogenesis and pathological roles in various diseases, J. Biochem. 153 (2013) 13-19.
    • (2013) J. Biochem. , vol.153 , pp. 13-19
    • Shibuya, M.1
  • 28
    • 0032741283 scopus 로고    scopus 로고
    • Antibodies to vascular endothelial growth factor enhance the efficacy of cancer immunotherapy by improving endogenous dendritic cell function
    • D.I. Gabrilovich, T. Ishida, S. Nadaf, J.E. Ohm, D.P. Carbone, Antibodies to vascular endothelial growth factor enhance the efficacy of cancer immunotherapy by improving endogenous dendritic cell function, Clin. Cancer Res. 5 (1999) 2963-2970.
    • (1999) Clin. Cancer Res. , vol.5 , pp. 2963-2970
    • Gabrilovich, D.I.1    Ishida, T.2    Nadaf, S.3    Ohm, J.E.4    Carbone, D.P.5
  • 29
    • 77950519079 scopus 로고    scopus 로고
    • Antitumour and immune-adjuvant activities of protein-tyrosine kinase inhibitors
    • B. Seliger, C. Massa, B. Rini, J. Ko, J. Finke, Antitumour and immune-adjuvant activities of protein-tyrosine kinase inhibitors, Trends Mol. Med. 16 (2010) 184-192.
    • (2010) Trends Mol. Med. , vol.16 , pp. 184-192
    • Seliger, B.1    Massa, C.2    Rini, B.3    Ko, J.4    Finke, J.5
  • 30
    • 44949093775 scopus 로고    scopus 로고
    • Culture of HEK293-EBNA1 cells for production of recombinant proteins
    • pdb prot4976
    • R. Tom, L. Bisson, Y. Durocher, Culture of HEK293-EBNA1 cells for production of recombinant proteins, CSH Protoc. (2008) pdb prot4976.
    • (2008) CSH Protoc.
    • Tom, R.1    Bisson, L.2    Durocher, Y.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.