메뉴 건너뛰기




Volumn 1, Issue 3, 2002, Pages 219-227

Molecular mechanisms of lymphangiogenesis in health and disease

Author keywords

[No Author keywords available]

Indexed keywords

VASCULOTROPIN C; VASCULOTROPIN D; ENDOTHELIAL CELL GROWTH FACTOR; GROWTH FACTOR RECEPTOR; PROTEIN TYROSINE KINASE; VASCULOTROPIN RECEPTOR 3;

EID: 0036527585     PISSN: 15356108     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1535-6108(02)00051-X     Document Type: Review
Times cited : (619)

References (73)
  • 1
    • 0031905861 scopus 로고    scopus 로고
    • Vascular endothelial growth factor D (VEGF-D) is a ligand for the tyrosine kinases VEGF receptor 2 (Flk1) and VEGF receptor 3 (Flt4)
    • Achen, M.G., Jeltsch, M., Kukk, E., Makinen, T., Vitali, A., Wilks, A.F., Alitalo, K., and Stacker, S.A. (1998). Vascular endothelial growth factor D (VEGF-D) is a ligand for the tyrosine kinases VEGF receptor 2 (Flk1) and VEGF receptor 3 (Flt4). Proc. Natl. Acad. Sci. USA 95, 548-553.
    • (1998) Proc. Natl. Acad. Sci. USA , vol.95 , pp. 548-553
    • Achen, M.G.1    Jeltsch, M.2    Kukk, E.3    Makinen, T.4    Vitali, A.5    Wilks, A.F.6    Alitalo, K.7    Stacker, S.A.8
  • 5
    • 0033593793 scopus 로고    scopus 로고
    • LYVE-1, a new homologue of the CD44 glycoprotein, is a lymph-specific receptor for hyaluronan
    • Banerji, S., Ni, J., Wang, S.X., Clasper, S., Su, J., Tammi, R., Jones, M., and Jackson, D.G. (1999). LYVE-1, a new homologue of the CD44 glycoprotein, is a lymph-specific receptor for hyaluronan. J. Cell Biol. 144, 789-801.
    • (1999) J. Cell Biol. , vol.144 , pp. 789-801
    • Banerji, S.1    Ni, J.2    Wang, S.X.3    Clasper, S.4    Su, J.5    Tammi, R.6    Jones, M.7    Jackson, D.G.8
  • 7
    • 0035915771 scopus 로고    scopus 로고
    • Lymphatic microvessel density as a novel prognostic factor in early- Stage invasive cervical cancer
    • Birner, P., Schindl, M., Obermair, A., Breitenecker, G., Kowalski, H., and Oberhuber, G. (2001). Lymphatic microvessel density as a novel prognostic factor in early- stage invasive cervical cancer. Int. J. Cancer 95, 29-33.
    • (2001) Int. J. Cancer , vol.95 , pp. 29-33
    • Birner, P.1    Schindl, M.2    Obermair, A.3    Breitenecker, G.4    Kowalski, H.5    Oberhuber, G.6
  • 10
    • 0034076189 scopus 로고    scopus 로고
    • Mechanisms of angiogenesis and arteriogenesis
    • Carmeliet, P. (2000). Mechanisms of angiogenesis and arteriogenesis. Nat. Med. 6, 389-395.
    • (2000) Nat. Med. , vol.6 , pp. 389-395
    • Carmeliet, P.1
  • 11
    • 0034648765 scopus 로고    scopus 로고
    • Angiogenesis in cancer and other diseases
    • Carmeliet, P., and Jain, R.K. (2000). Angiogenesis in cancer and other diseases. Nature 407, 249-257.
    • (2000) Nature , vol.407 , pp. 249-257
    • Carmeliet, P.1    Jain, R.K.2
  • 12
    • 19244379078 scopus 로고    scopus 로고
    • Synergism between vascular endothelial growth factor and placental growth factor contributes to angiogenesis and plasma extravasation in pathological conditions
    • Carmeliet, P., Moons, L., Luttun, A., Vincenti, V., Compernolle, V., De Mol, M., Wu, Y., Bono, F., Devy, L., Beck, H., et al. (2001). Synergism between vascular endothelial growth factor and placental growth factor contributes to angiogenesis and plasma extravasation in pathological conditions. Nat. Med. 7, 575-583.
    • (2001) Nat. Med. , vol.7 , pp. 575-583
    • Carmeliet, P.1    Moons, L.2    Luttun, A.3    Vincenti, V.4    Compernolle, V.5    De Mol, M.6    Wu, Y.7    Bono, F.8    Devy, L.9    Beck, H.10
  • 13
    • 0035890540 scopus 로고    scopus 로고
    • LYVE-1 is not restricted to the lymph vessels: Expression in normal liver blood sinusoids and down-regulation in human liver cancer and cirrhosis
    • Carreira, C.M., Nasser, S.M., di Tomaso, E., Padera, T.P., Boucher, Y., Tomarev, S.I., and Jain, R.K. (2001). LYVE-1 is not restricted to the lymph vessels: expression in normal liver blood sinusoids and down-regulation in human liver cancer and cirrhosis. Cancer Res. 61, 8079-8084.
    • (2001) Cancer Res. , vol.61 , pp. 8079-8084
    • Carreira, C.M.1    Nasser, S.M.2    Di Tomaso, E.3    Padera, T.P.4    Boucher, Y.5    Tomarev, S.I.6    Jain, R.K.7
  • 15
    • 84944487950 scopus 로고
    • Observations on the new growth of lymphatic vessels as seen in transparent chambers introduced into the rabbit's ear
    • Clark, E., and Clark, E. (1932). Observations on the new growth of lymphatic vessels as seen in transparent chambers introduced into the rabbit's ear. Am. J. Anat. 57, 43-87.
    • (1932) Am. J. Anat. , vol.57 , pp. 43-87
    • Clark, E.1    Clark, E.2
  • 17
    • 0034104295 scopus 로고    scopus 로고
    • VPF/VEGF and the angiogenic response
    • Dvorak, H.F. (2000). VPF/VEGF and the angiogenic response. Semin. Perinatol. 24, 75-78.
    • (2000) Semin. Perinatol. , vol.24 , pp. 75-78
    • Dvorak, H.F.1
  • 19
    • 0033646615 scopus 로고    scopus 로고
    • Mutations in FOXC2 (MFH-1), a fork-head family transcription factor, are responsible for the hereditary lymphedema-distichiasis syndrome
    • Fang, J., Dagenais, S.L., Erickson, R.P., Arlt, M.F., Glynn, M.W., Gorski, J.L., Seaver, L.H., and Glover, T.W. (2000). Mutations in FOXC2 (MFH-1), a fork-head family transcription factor, are responsible for the hereditary lymphedema-distichiasis syndrome. Am. J. Hum. Genet. 67, 1382-1388.
    • (2000) Am. J. Hum. Genet. , vol.67 , pp. 1382-1388
    • Fang, J.1    Dagenais, S.L.2    Erickson, R.P.3    Arlt, M.F.4    Glynn, M.W.5    Gorski, J.L.6    Seaver, L.H.7    Glover, T.W.8
  • 20
    • 0034979273 scopus 로고    scopus 로고
    • Role of vascular endothelial growth factor in regulation of physiological angiogenesis
    • Ferrara, N. (2001). Role of vascular endothelial growth factor in regulation of physiological angiogenesis. Am. J. Physiol. Cell Physiol. 280, C1358-C1366.
    • (2001) Am. J. Physiol. Cell Physiol. , vol.280
    • Ferrara, N.1
  • 22
    • 0034499722 scopus 로고    scopus 로고
    • Specific adhesion molecules bind anchoring filaments and endothelial cells in human skin initial lymphatics
    • Gerli, R., Solito, R., Weber, E., and Agliano, M. (2000). Specific adhesion molecules bind anchoring filaments and endothelial cells in human skin initial lymphatics. Lymphology 33, 148-157.
    • (2000) Lymphology , vol.33 , pp. 148-157
    • Gerli, R.1    Solito, R.2    Weber, E.3    Agliano, M.4
  • 23
    • 0030576517 scopus 로고    scopus 로고
    • Patterns and emerging mechanisms of the angiogenic switch during tumorigenesis
    • Hanahan, D., and Folkman, J. (1996). Patterns and emerging mechanisms of the angiogenic switch during tumorigenesis. Cell 86, 353-364.
    • (1996) Cell , vol.86 , pp. 353-364
    • Hanahan, D.1    Folkman, J.2
  • 26
    • 0002508403 scopus 로고
    • The anatomy and development of the jugular lymph sac in the domestic cat (Felis domestica)
    • Huntington, G.S., and McLure, C.F.W. (1908). The anatomy and development of the jugular lymph sac in the domestic cat (Felis domestica). Am. J. Anat. 2, 1-19.
    • (1908) Am. J. Anat. , vol.2 , pp. 1-19
    • Huntington, G.S.1    McLure, C.F.W.2
  • 27
    • 0034913816 scopus 로고    scopus 로고
    • LYVE-1, the lymphatic system and tumor lymphangiogenesis
    • Jackson, D.G., Prevo, R., Clasper, S., and Banerji, S. (2001). LYVE-1, the lymphatic system and tumor lymphangiogenesis. Trends Immunol. 22, 317-321.
    • (2001) Trends Immunol. , vol.22 , pp. 317-321
    • Jackson, D.G.1    Prevo, R.2    Clasper, S.3    Banerji, S.4
  • 28
    • 0037139527 scopus 로고    scopus 로고
    • Intratumoral lymphatic vessels: A case of mistaken identity or malfunction?
    • Jain, R.K., and Fenton, B.T. (2002). Intratumoral lymphatic vessels: a case of mistaken identity or malfunction? J. Natl. Cancer Inst. 94, 417-421.
    • (2002) J. Natl. Cancer Inst. , vol.94 , pp. 417-421
    • Jain, R.K.1    Fenton, B.T.2
  • 29
    • 0035653288 scopus 로고    scopus 로고
    • Vessels of death or life
    • Jain, R.K., and Carmeliet, P.F. (2001). Vessels of death or life. Sci. Am. 285, 38-45.
    • (2001) Sci. Am. , vol.285 , pp. 38-45
    • Jain, R.K.1    Carmeliet, P.F.2
  • 30
    • 0036548794 scopus 로고    scopus 로고
    • Dissecting tumors using intravital microscopy
    • in press
    • Jain, R.K., Munn, L.L., and Fukumura, D. (2002). Dissecting tumors using intravital microscopy. Nat. Rev. Cancer, in press.
    • (2002) Nat. Rev. Cancer
    • Jain, R.K.1    Munn, L.L.2    Fukumura, D.3
  • 32
    • 0030118083 scopus 로고    scopus 로고
    • A novel vascular endothelial growth factor, VEGF-C, is a ligand for the Flt4 (VEGFR-3) and KDR (VEGFR-2) receptor tyrosine kinases
    • Joukov, V., Pajusola, K., Kaipainen, A., Chilov, D., Lahtinen, I., Kukk, E., Saksela, O., Kalkkinen, N., and Alitalo, K. (1996). A novel vascular endothelial growth factor, VEGF-C, is a ligand for the Flt4 (VEGFR-3) and KDR (VEGFR-2) receptor tyrosine kinases. EMBO J. 15, 1751.
    • (1996) EMBO J. , vol.15 , pp. 1751
    • Joukov, V.1    Pajusola, K.2    Kaipainen, A.3    Chilov, D.4    Lahtinen, I.5    Kukk, E.6    Saksela, O.7    Kalkkinen, N.8    Alitalo, K.9
  • 35
    • 0035866775 scopus 로고    scopus 로고
    • Vascular endothelial growth factor (VEGF)-C differentially affects tumor vascular function and leukocyte recruitment: Role of VEGF- Receptor 2 and host VEGF-A
    • Kadambi, A., Carreira, C.M., Yun, C.O., Padera, T.P., Dolmans, D.E., Carmeliet, P., Fukumura, D., and Jain, R.K. (2001). Vascular endothelial growth factor (VEGF)-C differentially affects tumor vascular function and leukocyte recruitment: role of VEGF- receptor 2 and host VEGF-A. Cancer Res. 61, 2404-2408.
    • (2001) Cancer Res. , vol.61 , pp. 2404-2408
    • Kadambi, A.1    Carreira, C.M.2    Yun, C.O.3    Padera, T.P.4    Dolmans, D.E.5    Carmeliet, P.6    Fukumura, D.7    Jain, R.K.8
  • 37
    • 0034693879 scopus 로고    scopus 로고
    • Vascular endothelial growth factor receptors in the regulation of angiogenesis and lymphangiogenesis
    • Karkkainen, M.J., and Petrova, T.V. (2000). Vascular endothelial growth factor receptors in the regulation of angiogenesis and lymphangiogenesis. Oncogene 19, 5598-5605.
    • (2000) Oncogene , vol.19 , pp. 5598-5605
    • Karkkainen, M.J.1    Petrova, T.V.2
  • 40
    • 0035903290 scopus 로고    scopus 로고
    • Lymphatic vessels as targets of tumor therapy?
    • Karpanen, T., and Alitalo, K. (2001). Lymphatic vessels as targets of tumor therapy? J. Exp. Med. 194, F37-42.
    • (2001) J. Exp. Med. , vol.194
    • Karpanen, T.1    Alitalo, K.2
  • 41
    • 0035266283 scopus 로고    scopus 로고
    • Vascular endothelial growth factor C promotes tumor lymphangiogenesis and intralymphatic tumor growth
    • Karpanen, T., Egeblad, M., Karkkainen, M.J., Kubo, H., Yla-Herttuala, S., Jaattela, M., and Alitalo, K. (2001). Vascular endothelial growth factor C promotes tumor lymphangiogenesis and intralymphatic tumor growth. Cancer Res. 61, 1786-1790.
    • (2001) Cancer Res. , vol.61 , pp. 1786-1790
    • Karpanen, T.1    Egeblad, M.2    Karkkainen, M.J.3    Kubo, H.4    Yla-Herttuala, S.5    Jaattela, M.6    Alitalo, K.7
  • 42
    • 18544393909 scopus 로고    scopus 로고
    • Involvement of vascular endothelial growth factor receptor-3 in maintenance of integrity of endothelial cell lining during tumor angiogenesis
    • Kubo, H., Fujiwara, T., Jussila, L., Hashi, H., Ogawa, M., Shimizu, K., Awane, M., Sakai, Y., Takabayashi, A., Alitalo, K., et al. (2000). Involvement of vascular endothelial growth factor receptor-3 in maintenance of integrity of endothelial cell lining during tumor angiogenesis. Blood 96, 546-553.
    • (2000) Blood , vol.96 , pp. 546-553
    • Kubo, H.1    Fujiwara, T.2    Jussila, L.3    Hashi, H.4    Ogawa, M.5    Shimizu, K.6    Awane, M.7    Sakai, Y.8    Takabayashi, A.9    Alitalo, K.10
  • 43
    • 0037172970 scopus 로고    scopus 로고
    • Blockade of vascular endothelial growth factor receptor-3 signaling inhibits fibroblast growth factor-2 induced lymphangiogenesis in mouse cornea
    • in press
    • Kubo, H., Cao, R., Brakenhielm, E., Cao, Y., and Alitalo, K. (2002). Blockade of vascular endothelial growth factor receptor-3 signaling inhibits fibroblast growth factor-2 induced lymphangiogenesis in mouse cornea. Proc. Natl. Acad. Sci. USA, in press.
    • (2002) Proc. Natl. Acad. Sci. USA
    • Kubo, H.1    Cao, R.2    Brakenhielm, E.3    Cao, Y.4    Alitalo, K.5
  • 44
    • 0030453355 scopus 로고    scopus 로고
    • VEGF-C receptor binding and pattern of expression with VEGFR-3 suggests a role in lymphatic vascular development
    • Kukk, E., Lymboussaki, A., Taira, S., Kaipainen, A., Jeltsch, M., Joukov, V., and Alitalo, K. (1996). VEGF-C receptor binding and pattern of expression with VEGFR-3 suggests a role in lymphatic vascular development. Development 122, 3829-3837.
    • (1996) Development , vol.122 , pp. 3829-3837
    • Kukk, E.1    Lymboussaki, A.2    Taira, S.3    Kaipainen, A.4    Jeltsch, M.5    Joukov, V.6    Alitalo, K.7
  • 45
    • 0017069413 scopus 로고
    • The structure of lymphatic capillaries in lymph formation
    • Leak, L.V. (1976). The structure of lymphatic capillaries in lymph formation. Fed. Proc. 35, 1863-1871.
    • (1976) Fed. Proc. , vol.35 , pp. 1863-1871
    • Leak, L.V.1
  • 50
  • 52
    • 0003136463 scopus 로고
    • A micro-lymphangiographic study of experimental wounds by second intention
    • Oden, B. (1960). A micro-lymphangiographic study of experimental wounds by second intention. Acta Chir. Scand. 120, 100-114.
    • (1960) Acta Chir. Scand. , vol.120 , pp. 100-114
    • Oden, B.1
  • 53
    • 0031213636 scopus 로고    scopus 로고
    • VEGF and VEGF-C: Specific induction of angiogenesis and lymphangiogenesis in the differentiated avian chorioallantoic membrane
    • Oh, S.J., Jeltsch, M.M., Birkenhäger, R., McCarthy, J.E.G., Weich, H.A., Christ, B., Alitalo, K., and Wilting, J. (1997). VEGF and VEGF-C: Specific induction of angiogenesis and lymphangiogenesis in the differentiated avian chorioallantoic membrane. Dev. Biol. 188, 96-109.
    • (1997) Dev. Biol. , vol.188 , pp. 96-109
    • Oh, S.J.1    Jeltsch, M.M.2    Birkenhäger, R.3    McCarthy, J.E.G.4    Weich, H.A.5    Christ, B.6    Alitalo, K.7    Wilting, J.8
  • 54
    • 0035794238 scopus 로고    scopus 로고
    • In fibroblasts Vegf-D expression is induced by cell-cell contact mediated by cadherin-11
    • Orlandini, M., and Oliviero, S. (2001). In fibroblasts Vegf-D expression is induced by cell-cell contact mediated by cadherin-11. J. Biol. Chem. 276, 6576-6581.
    • (2001) J. Biol. Chem. , vol.276 , pp. 6576-6581
    • Orlandini, M.1    Oliviero, S.2
  • 55
    • 0029859193 scopus 로고    scopus 로고
    • Identification of a c-fos-induced gene that is related to the platelet- derived growth factor/vascular endothelial growth factor family
    • Orlandini, M., Marconcini, L., Ferruzzi, R., and Oliviero, S. (1996). Identification of a c-fos-induced gene that is related to the platelet- derived growth factor/vascular endothelial growth factor family. Proc. Natl. Acad. Sci. USA 93, 11675-11680.
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 11675-11680
    • Orlandini, M.1    Marconcini, L.2    Ferruzzi, R.3    Oliviero, S.4
  • 56
    • 0033846016 scopus 로고    scopus 로고
    • Vascular endothelial growth factor receptor-3 in lymphangiogenesis in wound healing
    • Paavonen, K., Puolakkainen, P., Jussila, L., Jahkola, T., and Alitalo, K. (2000). Vascular endothelial growth factor receptor-3 in lymphangiogenesis in wound healing. Am. J. Pathol. 156, 1499-1504.
    • (2000) Am. J. Pathol. , vol.156 , pp. 1499-1504
    • Paavonen, K.1    Puolakkainen, P.2    Jussila, L.3    Jahkola, T.4    Alitalo, K.5
  • 57
    • 0033814892 scopus 로고    scopus 로고
    • VEGF-C and VEGF-D expression in neuroendocrine cells and their receptor, VEGFR-3, in fenestrated blood vessels in human tissues
    • Partanen, T.A., Arola, J., Saaristo, A., Jussila, L., Ora, A., Miettinen, M., Stacker, S.A., Achen, M.G., and Alitalo, K. (2000). VEGF-C and VEGF-D expression in neuroendocrine cells and their receptor, VEGFR-3, in fenestrated blood vessels in human tissues. FASEB J. 14, 2087-2096.
    • (2000) FASEB J. , vol.14 , pp. 2087-2096
    • Partanen, T.A.1    Arola, J.2    Saaristo, A.3    Jussila, L.4    Ora, A.5    Miettinen, M.6    Stacker, S.A.7    Achen, M.G.8    Alitalo, K.9
  • 58
    • 0034899437 scopus 로고    scopus 로고
    • Lymphangiogenesis and tumor metastasis: Myth or reality?
    • Pepper, M.S. (2001). Lymphangiogenesis and tumor metastasis: myth or reality? Clin. Cancer Res. 7, 462-468.
    • (2001) Clin. Cancer Res. , vol.7 , pp. 462-468
    • Pepper, M.S.1
  • 59
    • 84981813798 scopus 로고
    • On the origin of the lymphatic system from the veins and the development of the lymph hearts and thoracic duct in the pig
    • Sabin, F.R. (1902). On the origin of the lymphatic system from the veins and the development of the lymph hearts and thoracic duct in the pig. Am. J. Anat. 1.
    • (1902) Am. J. Anat. , vol.1
    • Sabin, F.R.1
  • 62
    • 0033402190 scopus 로고    scopus 로고
    • Vascular endothelial growth factor-C (VEGF-C) and its receptors KDR and flt-4 are expressed in AIDS-associated Kaposi's sarcoma
    • Skobe, M., Brown, L.F., Tognazzi, K., Ganju, R.K., Dezube, B.J., Alitalo, K., and Detmar, M. (1999). Vascular endothelial growth factor-C (VEGF-C) and its receptors KDR and flt-4 are expressed in AIDS-associated Kaposi's sarcoma. J. Invest. Dermatol. 113, 1047-1053.
    • (1999) J. Invest. Dermatol. , vol.113 , pp. 1047-1053
    • Skobe, M.1    Brown, L.F.2    Tognazzi, K.3    Ganju, R.K.4    Dezube, B.J.5    Alitalo, K.6    Detmar, M.7
  • 68
    • 0035834793 scopus 로고    scopus 로고
    • Stimulation of beta 1 integrin induces tyrosine phosphorylation of vascular endothelial growth factor receptor-3 and modulates cell migration
    • Wang, J.F., Zhang, X.F., and Groopman, J.E. (2001). Stimulation of beta 1 integrin induces tyrosine phosphorylation of vascular endothelial growth factor receptor-3 and modulates cell migration. J. Biol. Chem. 276, 41950-41957.
    • (2001) J. Biol. Chem. , vol.276 , pp. 41950-41957
    • Wang, J.F.1    Zhang, X.F.2    Groopman, J.E.3
  • 70
    • 0033578853 scopus 로고    scopus 로고
    • Prox1 function is required for the development of the murine lymphatic system
    • Wigle, J.T., and Oliver, G. (1999). Prox1 function is required for the development of the murine lymphatic system. Cell 98, 769-778.
    • (1999) Cell , vol.98 , pp. 769-778
    • Wigle, J.T.1    Oliver, G.2
  • 72
    • 0030635889 scopus 로고    scopus 로고
    • Lymphangiogenesis: Mechanisms, significance and clinical implications
    • I.D. Goldberg, and E. M. Rosen, eds. (Basel, BirkhäuserVerlag,)
    • Witte, M.H., Way, D.L., Witte, C.L., and Bernas, M. (1997). Lymphangiogenesis: Mechanisms, significance and clinical implications. In Regulation of angiogenesis, I.D. Goldberg, and E. M. Rosen, eds. (Basel, BirkhäuserVerlag,), pp. 65-112.
    • (1997) Regulation of Angiogenesis , pp. 65-112
    • Witte, M.H.1    Way, D.L.2    Witte, C.L.3    Bernas, M.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.