메뉴 건너뛰기




Volumn 91, Issue 6, 2014, Pages 299-310

Extracellular vesicles from MDA-MB-231 breast cancer cells stimulated with linoleic acid promote an EMT-like process in MCF10A cells

Author keywords

Breast cancer; EMT; Extracellular vesicles; MCF10A; MDA MB 231

Indexed keywords

GELATINASE A; GELATINASE B; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; LINOLEIC ACID; NERVE CELL ADHESION MOLECULE; UVOMORULIN; VIMENTIN; CADHERIN; CULTURE MEDIUM; MATRIX METALLOPROTEINASE;

EID: 84921974395     PISSN: 09523278     EISSN: 15322823     Source Type: Journal    
DOI: 10.1016/j.plefa.2014.09.002     Document Type: Article
Times cited : (56)

References (50)
  • 1
    • 77952365658 scopus 로고    scopus 로고
    • Microvesicles: mediators of extracellular communication during cancer progression
    • Muralidharan-Chari V., Clancy J.W., Sedgwick A., D'Souza-Schorey C. Microvesicles: mediators of extracellular communication during cancer progression. J. Cell Sci. 2010, 123:1603-1611.
    • (2010) J. Cell Sci. , vol.123 , pp. 1603-1611
    • Muralidharan-Chari, V.1    Clancy, J.W.2    Sedgwick, A.3    D'Souza-Schorey, C.4
  • 2
  • 3
    • 19944434048 scopus 로고    scopus 로고
    • Measuring circulating cell-derived microparticles
    • Jy W., Horstman L.L., Jimenez J.J., et al. Measuring circulating cell-derived microparticles. J. Thromb. Haemost. 2004, 2:1842-1851.
    • (2004) J. Thromb. Haemost. , vol.2 , pp. 1842-1851
    • Jy, W.1    Horstman, L.L.2    Jimenez, J.J.3
  • 4
    • 33244463813 scopus 로고    scopus 로고
    • Complex networks orchestrate epithelial-mesenchymal transitions
    • Thiery J.P., Sleeman J.P. Complex networks orchestrate epithelial-mesenchymal transitions. Nat. Rev. Mol. Cell Biol. 2006, 7:131-142.
    • (2006) Nat. Rev. Mol. Cell Biol. , vol.7 , pp. 131-142
    • Thiery, J.P.1    Sleeman, J.P.2
  • 5
    • 20744439516 scopus 로고    scopus 로고
    • The mesenchymal cell, its role in the embryo, and the remarkable signaling mechanisms that create it
    • Hay E.D. The mesenchymal cell, its role in the embryo, and the remarkable signaling mechanisms that create it. Dev. Dyn. 2005, 233:706-720.
    • (2005) Dev. Dyn. , vol.233 , pp. 706-720
    • Hay, E.D.1
  • 6
    • 24644480749 scopus 로고    scopus 로고
    • Molecular requirements for epithelial-mesenchymal transition during tumor progression
    • Huber M.A., Kraut N., Beug H. Molecular requirements for epithelial-mesenchymal transition during tumor progression. Curr. Opin. Cell Biol. 2005, 17:548-558.
    • (2005) Curr. Opin. Cell Biol. , vol.17 , pp. 548-558
    • Huber, M.A.1    Kraut, N.2    Beug, H.3
  • 7
    • 33645302628 scopus 로고    scopus 로고
    • The epithelial-mesenchymal transition: new insights in signaling, development, and disease
    • Lee J.M., Dedhar S., Kalluri R., Thompson E.W. The epithelial-mesenchymal transition: new insights in signaling, development, and disease. J. Cell Biol. 2006, 172:973-981.
    • (2006) J. Cell Biol. , vol.172 , pp. 973-981
    • Lee, J.M.1    Dedhar, S.2    Kalluri, R.3    Thompson, E.W.4
  • 8
    • 77954860342 scopus 로고    scopus 로고
    • Epithelial-mesenchymal transition in cancer: parallels between normal development and tumor progression
    • Micalizzi D.S., Farabaugh S.M., Ford H.L. Epithelial-mesenchymal transition in cancer: parallels between normal development and tumor progression. J. Mammary Gland Biol. Neoplasia 2010, 15:117-134.
    • (2010) J. Mammary Gland Biol. Neoplasia , vol.15 , pp. 117-134
    • Micalizzi, D.S.1    Farabaugh, S.M.2    Ford, H.L.3
  • 9
    • 56449119220 scopus 로고    scopus 로고
    • Too much linoleic acid promotes inflammation-doesn't it?
    • Fritsche K.L. Too much linoleic acid promotes inflammation-doesn't it?. Prostaglandins Leukot. Essent. Fatty Acids 2008, 79:173-175.
    • (2008) Prostaglandins Leukot. Essent. Fatty Acids , vol.79 , pp. 173-175
    • Fritsche, K.L.1
  • 10
    • 0035160023 scopus 로고    scopus 로고
    • Polyunsaturated fatty acids, inflammation, and immunity
    • Calder P.C. Polyunsaturated fatty acids, inflammation, and immunity. Lipids 2001, 36:1007-1024.
    • (2001) Lipids , vol.36 , pp. 1007-1024
    • Calder, P.C.1
  • 12
    • 38649097529 scopus 로고    scopus 로고
    • Unsaturated fatty acids promote proliferation via ERK1/2 and Akt pathway in bovine mammary epithelial cells
    • Yonezawa T., Haga S., Kobayashi Y., Katoh K., Obara Y. Unsaturated fatty acids promote proliferation via ERK1/2 and Akt pathway in bovine mammary epithelial cells. Biochem. Biophys. Res. Commun. 2008, 367:729-735.
    • (2008) Biochem. Biophys. Res. Commun. , vol.367 , pp. 729-735
    • Yonezawa, T.1    Haga, S.2    Kobayashi, Y.3    Katoh, K.4    Obara, Y.5
  • 13
    • 70350681047 scopus 로고    scopus 로고
    • Free fatty acids enhance breast cancer cell migration through plasminogen activator inhibitor-1 and SMAD4
    • Byon C.H., Hardy R.W., Ren C., et al. Free fatty acids enhance breast cancer cell migration through plasminogen activator inhibitor-1 and SMAD4. Lab. Investig. 2009, 89:1221-1228.
    • (2009) Lab. Investig. , vol.89 , pp. 1221-1228
    • Byon, C.H.1    Hardy, R.W.2    Ren, C.3
  • 14
    • 0032493658 scopus 로고    scopus 로고
    • Selective enrichment of tetraspan proteins on the internal vesicles of multivesicular endosomes and on exosomes secreted by human B-lymphocytes
    • Escola J.M., Kleijmeer M.J., Stoorvogel W., Griffith J.M., Yoshie O., Geuze H.J. Selective enrichment of tetraspan proteins on the internal vesicles of multivesicular endosomes and on exosomes secreted by human B-lymphocytes. J. Biol. Chem. 1998, 273:20121-20127.
    • (1998) J. Biol. Chem. , vol.273 , pp. 20121-20127
    • Escola, J.M.1    Kleijmeer, M.J.2    Stoorvogel, W.3    Griffith, J.M.4    Yoshie, O.5    Geuze, H.J.6
  • 15
    • 35048816607 scopus 로고    scopus 로고
    • The transferrin receptor and the tetraspanin web molecules CD9, CD81, and CD9P-1 are differentially sorted into exosomes after TPA treatment of K562 cells
    • Abache T., Le Naour F., Planchon S., Harper F., Boucheix C., Rubinstein E. The transferrin receptor and the tetraspanin web molecules CD9, CD81, and CD9P-1 are differentially sorted into exosomes after TPA treatment of K562 cells. J. Cell Biochem. 2007, 102:650-664.
    • (2007) J. Cell Biochem. , vol.102 , pp. 650-664
    • Abache, T.1    Le Naour, F.2    Planchon, S.3    Harper, F.4    Boucheix, C.5    Rubinstein, E.6
  • 16
    • 84876867466 scopus 로고    scopus 로고
    • Elevated concentration of microvesicles isolated from peripheral blood in breast cancer patients
    • Galindo-Hernandez O., Villegas-Comonfort S., Candanedo F., et al. Elevated concentration of microvesicles isolated from peripheral blood in breast cancer patients. Arch. Med. Res. 2013, 44:208-214.
    • (2013) Arch. Med. Res. , vol.44 , pp. 208-214
    • Galindo-Hernandez, O.1    Villegas-Comonfort, S.2    Candanedo, F.3
  • 17
    • 26644432498 scopus 로고    scopus 로고
    • Type IV collagen induces STAT5 activation in MCF7 human breast cancer cells
    • Robledo T., Arriaga-Pizano L., Lopez-Perez M., Salazar E.P. Type IV collagen induces STAT5 activation in MCF7 human breast cancer cells. Matrix Biol. 2005, 24:469-477.
    • (2005) Matrix Biol. , vol.24 , pp. 469-477
    • Robledo, T.1    Arriaga-Pizano, L.2    Lopez-Perez, M.3    Salazar, E.P.4
  • 18
    • 0037427072 scopus 로고    scopus 로고
    • Melanoma cell migration to type IV collagen requires activation of NF-kappaB
    • Hodgson L., Henderson A.J., Dong C. Melanoma cell migration to type IV collagen requires activation of NF-kappaB. Oncogene 2003, 22:98-108.
    • (2003) Oncogene , vol.22 , pp. 98-108
    • Hodgson, L.1    Henderson, A.J.2    Dong, C.3
  • 19
    • 70450142560 scopus 로고    scopus 로고
    • Inflammation and EMT: an alliance towards organ fibrosis and cancer progression
    • Lopez-Novoa J.M., Nieto M.A. Inflammation and EMT: an alliance towards organ fibrosis and cancer progression. EMBO Mol. Med. 2009, 1:303-314.
    • (2009) EMBO Mol. Med. , vol.1 , pp. 303-314
    • Lopez-Novoa, J.M.1    Nieto, M.A.2
  • 21
    • 85028118470 scopus 로고    scopus 로고
    • Microvesicles as mediators of intercellular communication in cancer-the emerging science of cellular 'debris'
    • Lee T.H., D'Asti E., Magnus N., Al-Nedawi K., Meehan B., Rak J. Microvesicles as mediators of intercellular communication in cancer-the emerging science of cellular 'debris'. Semin. Immunopathol. 2011, 33:455-467.
    • (2011) Semin. Immunopathol. , vol.33 , pp. 455-467
    • Lee, T.H.1    D'Asti, E.2    Magnus, N.3    Al-Nedawi, K.4    Meehan, B.5    Rak, J.6
  • 22
    • 79953229234 scopus 로고    scopus 로고
    • Cancer cell-derived microvesicles induce transformation by transferring tissue transglutaminase and fibronectin to recipient cells
    • Antonyak M.A., Li B., Boroughs L.K., et al. Cancer cell-derived microvesicles induce transformation by transferring tissue transglutaminase and fibronectin to recipient cells. Proc. Natl. Acad. Sci. USA 2011, 108:4852-4857.
    • (2011) Proc. Natl. Acad. Sci. USA , vol.108 , pp. 4852-4857
    • Antonyak, M.A.1    Li, B.2    Boroughs, L.K.3
  • 23
    • 57049103401 scopus 로고    scopus 로고
    • Glioblastoma microvesicles transport RNA and proteins that promote tumour growth and provide diagnostic biomarkers
    • Skog J., Wurdinger T., van Rijn S., et al. Glioblastoma microvesicles transport RNA and proteins that promote tumour growth and provide diagnostic biomarkers. Nat. Cell Biol. 2008, 10:1470-1476.
    • (2008) Nat. Cell Biol. , vol.10 , pp. 1470-1476
    • Skog, J.1    Wurdinger, T.2    van Rijn, S.3
  • 25
    • 42749091317 scopus 로고    scopus 로고
    • Epithelial-mesenchymal transition and the invasive potential of tumors
    • Gavert N., Ben-Ze'ev A. Epithelial-mesenchymal transition and the invasive potential of tumors. Trends Mol. Med. 2008, 14:199-209.
    • (2008) Trends Mol. Med. , vol.14 , pp. 199-209
    • Gavert, N.1    Ben-Ze'ev, A.2
  • 26
    • 0037086277 scopus 로고    scopus 로고
    • The SLUG zinc-finger protein represses E-cadherin in breast cancer
    • Hajra K.M., Chen D.Y., Fearon E.R. The SLUG zinc-finger protein represses E-cadherin in breast cancer. Cancer Res. 2002, 62:1613-1618.
    • (2002) Cancer Res. , vol.62 , pp. 1613-1618
    • Hajra, K.M.1    Chen, D.Y.2    Fearon, E.R.3
  • 27
    • 20144388095 scopus 로고    scopus 로고
    • DeltaEF1 is a transcriptional repressor of E-cadherin and regulates epithelial plasticity in breast cancer cells
    • Eger A., Aigner K., Sonderegger S., et al. DeltaEF1 is a transcriptional repressor of E-cadherin and regulates epithelial plasticity in breast cancer cells. Oncogene 2005, 24:2375-2385.
    • (2005) Oncogene , vol.24 , pp. 2375-2385
    • Eger, A.1    Aigner, K.2    Sonderegger, S.3
  • 29
    • 40649088574 scopus 로고    scopus 로고
    • Src kinase regulates metalloproteinase-9 secretion induced by type IV collagen in MCF-7 human breast cancer cells
    • Cortes-Reynosa P., Robledo T., Macias-Silva M., Wu S.V., Salazar E.P. Src kinase regulates metalloproteinase-9 secretion induced by type IV collagen in MCF-7 human breast cancer cells. Matrix Biol. 2008, 27:220-231.
    • (2008) Matrix Biol. , vol.27 , pp. 220-231
    • Cortes-Reynosa, P.1    Robledo, T.2    Macias-Silva, M.3    Wu, S.V.4    Salazar, E.P.5
  • 30
    • 34547798981 scopus 로고    scopus 로고
    • Role of nuclear factor kappa B and reactive oxygen species in the tumor necrosis factor-alpha-induced epithelial-mesenchymal transition of MCF-7 cells
    • Dong R., Wang Q., He X.L., Chu Y.K., Lu J.G., Ma Q.J. Role of nuclear factor kappa B and reactive oxygen species in the tumor necrosis factor-alpha-induced epithelial-mesenchymal transition of MCF-7 cells. Braz. J. Med. Biol. Res. 2007, 40:1071-1078.
    • (2007) Braz. J. Med. Biol. Res. , vol.40 , pp. 1071-1078
    • Dong, R.1    Wang, Q.2    He, X.L.3    Chu, Y.K.4    Lu, J.G.5    Ma, Q.J.6
  • 31
    • 4344612243 scopus 로고    scopus 로고
    • NF-kappaB is essential for epithelial-mesenchymal transition and metastasis in a model of breast cancer progression
    • Huber M.A., Azoitei N., Baumann B., et al. NF-kappaB is essential for epithelial-mesenchymal transition and metastasis in a model of breast cancer progression. J. Clin. Investig. 2004, 114:569-581.
    • (2004) J. Clin. Investig. , vol.114 , pp. 569-581
    • Huber, M.A.1    Azoitei, N.2    Baumann, B.3
  • 32
    • 0344845283 scopus 로고    scopus 로고
    • Induction of myofibroblast MMP-9 transcription in three-dimensional collagen I gel cultures: regulation by NF-kappaB, AP-1 and Sp1
    • Takahra T., Smart D.E., Oakley F., Mann D.A. Induction of myofibroblast MMP-9 transcription in three-dimensional collagen I gel cultures: regulation by NF-kappaB, AP-1 and Sp1. Int. J. Biochem. Cell Biol. 2004, 36:353-363.
    • (2004) Int. J. Biochem. Cell Biol. , vol.36 , pp. 353-363
    • Takahra, T.1    Smart, D.E.2    Oakley, F.3    Mann, D.A.4
  • 33
    • 0033835861 scopus 로고    scopus 로고
    • Dietary fat and breast cancer
    • Lee M.M., Lin S.S. Dietary fat and breast cancer. Annu. Rev. Nutr. 2000, 20:221-248.
    • (2000) Annu. Rev. Nutr. , vol.20 , pp. 221-248
    • Lee, M.M.1    Lin, S.S.2
  • 34
    • 53649083161 scopus 로고    scopus 로고
    • Identification of a dietary pattern characterized by high-fat food choices associated with increased risk of breast cancer: the European Prospective Investigation into Cancer and Nutrition (EPIC)-Potsdam study
    • Schulz M., Hoffmann K., Weikert C., Nothlings U., Schulze M.B., Boeing H. Identification of a dietary pattern characterized by high-fat food choices associated with increased risk of breast cancer: the European Prospective Investigation into Cancer and Nutrition (EPIC)-Potsdam study. Br. J. Nutr. 2008, 100:942-946.
    • (2008) Br. J. Nutr. , vol.100 , pp. 942-946
    • Schulz, M.1    Hoffmann, K.2    Weikert, C.3    Nothlings, U.4    Schulze, M.B.5    Boeing, H.6
  • 35
    • 0033954765 scopus 로고    scopus 로고
    • Polyunsaturated fatty acids in the food chain in the United States
    • Kris-Etherton P.M., Taylor D.S., Yu-Poth S., et al. Polyunsaturated fatty acids in the food chain in the United States. Am. J. Clin. Nutr. 2000, 71:179S-188S.
    • (2000) Am. J. Clin. Nutr. , vol.71 , pp. 179S-188S
    • Kris-Etherton, P.M.1    Taylor, D.S.2    Yu-Poth, S.3
  • 36
    • 70349287329 scopus 로고    scopus 로고
    • Plasma fatty acid composition as a predictor of arterial stiffness and mortality
    • Anderson S.G., Sanders T.A., Cruickshank J.K. Plasma fatty acid composition as a predictor of arterial stiffness and mortality. Hypertension 2009, 53:839-845.
    • (2009) Hypertension , vol.53 , pp. 839-845
    • Anderson, S.G.1    Sanders, T.A.2    Cruickshank, J.K.3
  • 37
    • 32544451437 scopus 로고    scopus 로고
    • Relationship of plasma polyunsaturated fatty acids to circulating inflammatory markers
    • Ferrucci L., Cherubini A., Bandinelli S., et al. Relationship of plasma polyunsaturated fatty acids to circulating inflammatory markers. J. Clin. Endocrinol. Metab. 2006, 91:439-446.
    • (2006) J. Clin. Endocrinol. Metab. , vol.91 , pp. 439-446
    • Ferrucci, L.1    Cherubini, A.2    Bandinelli, S.3
  • 38
    • 84862618600 scopus 로고    scopus 로고
    • Tumor-derived microvesicles: shedding light on novel microenvironment modulators and prospective cancer biomarkers
    • D'Souza-Schorey C., Clancy J.W. Tumor-derived microvesicles: shedding light on novel microenvironment modulators and prospective cancer biomarkers. Genes Dev. 2012, 26:1287-1299.
    • (2012) Genes Dev. , vol.26 , pp. 1287-1299
    • D'Souza-Schorey, C.1    Clancy, J.W.2
  • 39
    • 77955488946 scopus 로고    scopus 로고
    • Membrane microvesicles: macromessengers in cancer disease and progression
    • Castellana D., Toti F., Freyssinet J.M. Membrane microvesicles: macromessengers in cancer disease and progression. Thromb. Res. 2010, 125(Suppl. 2):S84-S88.
    • (2010) Thromb. Res. , vol.125 , pp. S84-S88
    • Castellana, D.1    Toti, F.2    Freyssinet, J.M.3
  • 40
    • 23144442645 scopus 로고    scopus 로고
    • Regulation of cadherin-mediated adhesion in morphogenesis
    • Gumbiner B.M. Regulation of cadherin-mediated adhesion in morphogenesis. Nat. Rev. Mol. Cell Biol. 2005, 6:622-634.
    • (2005) Nat. Rev. Mol. Cell Biol. , vol.6 , pp. 622-634
    • Gumbiner, B.M.1
  • 41
    • 0033784843 scopus 로고    scopus 로고
    • The transcription factor snail controls epithelial-mesenchymal transitions by repressing E-cadherin expression
    • Cano A., Perez-Moreno M.A., Rodrigo I., et al. The transcription factor snail controls epithelial-mesenchymal transitions by repressing E-cadherin expression. Nat. Cell Biol. 2000, 2:76-83.
    • (2000) Nat. Cell Biol. , vol.2 , pp. 76-83
    • Cano, A.1    Perez-Moreno, M.A.2    Rodrigo, I.3
  • 42
    • 65549123466 scopus 로고    scopus 로고
    • Molecular mechanisms controlling E-cadherin expression in breast cancer
    • Baranwal S., Alahari S.K. Molecular mechanisms controlling E-cadherin expression in breast cancer. Biochem. Biophys. Res. Commun. 2009, 384:6-11.
    • (2009) Biochem. Biophys. Res. Commun. , vol.384 , pp. 6-11
    • Baranwal, S.1    Alahari, S.K.2
  • 43
    • 0344845003 scopus 로고    scopus 로고
    • Epithelial-mesenchymal transitions in development and pathologies
    • Thiery J.P. Epithelial-mesenchymal transitions in development and pathologies. Curr. Opin. Cell Biol. 2003, 15:740-746.
    • (2003) Curr. Opin. Cell Biol. , vol.15 , pp. 740-746
    • Thiery, J.P.1
  • 44
    • 0034695913 scopus 로고    scopus 로고
    • Exogenous expression of N-cadherin in breast cancer cells induces cell migration, invasion, and metastasis
    • Hazan R.B., Phillips G.R., Qiao R.F., Norton L., Aaronson S.A. Exogenous expression of N-cadherin in breast cancer cells induces cell migration, invasion, and metastasis. J. Cell Biol. 2000, 148:779-790.
    • (2000) J. Cell Biol. , vol.148 , pp. 779-790
    • Hazan, R.B.1    Phillips, G.R.2    Qiao, R.F.3    Norton, L.4    Aaronson, S.A.5
  • 45
    • 33747365847 scopus 로고    scopus 로고
    • Regulation of vimentin by SIP1 in human epithelial breast tumor cells
    • Bindels S., Mestdagt M., Vandewalle C., et al. Regulation of vimentin by SIP1 in human epithelial breast tumor cells. Oncogene 2006, 25:4975-4985.
    • (2006) Oncogene , vol.25 , pp. 4975-4985
    • Bindels, S.1    Mestdagt, M.2    Vandewalle, C.3
  • 46
    • 45149092780 scopus 로고    scopus 로고
    • NF-kappaB and epithelial to mesenchymal transition of cancer
    • Min C., Eddy S.F., Sherr D.H., Sonenshein G.E. NF-kappaB and epithelial to mesenchymal transition of cancer. J. Cell Biochem. 2008, 104:733-744.
    • (2008) J. Cell Biochem. , vol.104 , pp. 733-744
    • Min, C.1    Eddy, S.F.2    Sherr, D.H.3    Sonenshein, G.E.4
  • 47
    • 77954861244 scopus 로고    scopus 로고
    • Matrix metalloproteinase-induced epithelial-mesenchymal transition in breast cancer
    • Radisky E.S., Radisky D.C. Matrix metalloproteinase-induced epithelial-mesenchymal transition in breast cancer. J. Mammary Gland Biol. Neoplasia 2010, 15:201-212.
    • (2010) J. Mammary Gland Biol. Neoplasia , vol.15 , pp. 201-212
    • Radisky, E.S.1    Radisky, D.C.2
  • 48
    • 67649528138 scopus 로고    scopus 로고
    • Collective cell migration in morphogenesis, regeneration and cancer
    • Friedl P., Gilmour D. Collective cell migration in morphogenesis, regeneration and cancer. Nat. Rev. Mol. Cell Biol. 2009, 10:445-457.
    • (2009) Nat. Rev. Mol. Cell Biol. , vol.10 , pp. 445-457
    • Friedl, P.1    Gilmour, D.2
  • 49
    • 70449526719 scopus 로고    scopus 로고
    • Localized and reversible TGFbeta signalling switches breast cancer cells from cohesive to single cell motility
    • Giampieri S., Manning C., Hooper S., Jones L., Hill C.S., Sahai E. Localized and reversible TGFbeta signalling switches breast cancer cells from cohesive to single cell motility. Nat. Cell Biol. 2009, 11:1287-1296.
    • (2009) Nat. Cell Biol. , vol.11 , pp. 1287-1296
    • Giampieri, S.1    Manning, C.2    Hooper, S.3    Jones, L.4    Hill, C.S.5    Sahai, E.6
  • 50
    • 0345059766 scopus 로고    scopus 로고
    • Intravital imaging of cell movement in tumours
    • Condeelis J., Segall J.E. Intravital imaging of cell movement in tumours. Nat. Rev. Cancer 2003, 3:921-930.
    • (2003) Nat. Rev. Cancer , vol.3 , pp. 921-930
    • Condeelis, J.1    Segall, J.E.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.