Loss of RB1 induces non-proliferative retinoma: Increasing genomic instability correlates with progression to retinoblastoma

Human Molecular Genetics

Volumn 17, Issue 10, 2008, Pages 1363-1372

  Dimaras, Helen ^a,c   Khetan, Vikas ^e,g   Halliday, William ^e   Orlic, Marija ^a,c   Prigoda, Nadia L ^d   Piovesan, Beata ^d   Marrano, Paula ^a   Corson, Timothy W ^a,h   Eagle Jr , Ralph C ^f   Squire, Jeremy A ^a   Gallie, Brenda L ^a,b,c,d,e  

^a PRINCESS MARGARET HOSPITAL   (Canada)

^b UNIVERSITY OF TORONTO   (Canada)

^c UNIVERSITY HEALTH NETWORK   (Canada)

^d UNIVERSITY HEALTH NETWORK   (Canada)

^e HOSPITAL FOR SICK CHILDREN   (Canada)

^f WILLS EYE HOSPITAL   (United States)

^g Yale University ^*  (India)

^h YALE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

NEUROTROPHIN RECEPTOR P75; PROTEIN MDMX; PROTEIN P130; PROTEIN P16; RETINOBLASTOMA PROTEIN; TRANSCRIPTION FACTOR E2F3;

ANEUPLOIDY; ARTICLE; CARCINOGENESIS; CLINICAL OBSERVATION; CLONE; GENE EXPRESSION; GENE INACTIVATION; GENE LOSS; GENE NUMBER; GENOMIC INSTABILITY; HUMAN; HUMAN TISSUE; ONCOGENE; PRIORITY JOURNAL; PROTEIN EXPRESSION; RETINA DEVELOPMENT; RETINOBLASTOMA; SENESCENCE; TUMOR GROWTH; TUMOR SUPPRESSOR GENE;

ADULT; CELL PROLIFERATION; CYCLIN-DEPENDENT KINASE INHIBITOR P16; DISEASE PROGRESSION; GENE AMPLIFICATION; GENE DOSAGE; GENE SILENCING; GENOMIC INSTABILITY; HOMOZYGOTE; HUMANS; INFANT; KI-67 ANTIGEN; MALE; ONCOGENE PROTEINS; PROLIFERATING CELL NUCLEAR ANTIGEN; RETINOBLASTOMA; RETINOBLASTOMA PROTEIN; RETINOBLASTOMA-LIKE PROTEIN P130; TUMOR SUPPRESSOR PROTEIN P53; TUMOR SUPPRESSOR PROTEINS;

EID: 43049139917     PISSN: 09646906     EISSN: 14602083     Source Type: Journal    
DOI: 10.1093/hmg/ddn024     Document Type: Article

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