The paired basic amino acid-cleaving enzyme 4 (PACE4) is involved in the maturation of insulin receptor isoform B: An opportunity to reduce the specific insulin receptor-dependent effects of insulin-like growth factor 2 (IGF2)

Journal of Biological Chemistry

Volumn 290, Issue 5, 2015, Pages 2812-2821

  Kara, Imène ^a   Poggi, Marjorie ^a   Bonardo, Bernadette ^a   Govers, Roland ^a   Landrier, Jean Franҫois ^a   Tian, Sun ^b   Leibiger, Ingo ^c   Day, Robert ^d   Creemers, John W M ^e   Peiretti, Franck ^a  

^a INSERM   (France)

^b Nuolan Net   (Netherlands)

^c KAROLINSKA INSTITUTE   (Sweden)

^d UNIVERSITÉ DE SHERBROOKE   (Canada)

^e UNIVERSITY OF LEUVEN   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

CELL MEMBRANES; MAMMALS;

INSULIN ACTION; INSULIN RECEPTORS; INSULIN-LIKE GROWTH FACTOR 2; MAMMALIAN CELLS; MITOGENIC EFFECTS; PAIRED BASIC AMINO ACID CLEAVING ENZYME; PHARMACOLOGICAL INHIBITION; PROTEOLYTIC CLEAVAGE;

INSULIN;

ENZYME INHIBITOR; FURIN; INSULIN RECEPTOR; INSULIN RECEPTOR ISOFORM A; INSULIN RECEPTOR ISOFORM B; PAIRED BASIC AMINO ACID CLEAVING ENZYME 4; PROPROTEIN CONVERTASE INHIBITOR; SOMATOMEDIN B; UNCLASSIFIED DRUG; PCSK6 PROTEIN, HUMAN; SERINE PROTEINASE;

ANIMAL CELL; ARTICLE; CELL SURFACE; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME INHIBITION; HUMAN; HUMAN CELL; MITOGENESIS; MOUSE; NONHUMAN; PROTEIN CLEAVAGE; PROTEIN DEGRADATION; PROTEIN PHOSPHORYLATION; PROTEIN PROCESSING; PROTEIN PROTEIN INTERACTION; SIGNAL TRANSDUCTION; 3T3 CELL LINE; ANIMAL; CELL PROLIFERATION; GENETICS; HEK293 CELL LINE; HELA CELL LINE; IMMUNOBLOTTING; METABOLISM; REAL TIME POLYMERASE CHAIN REACTION;

MAMMALIA;

3T3-L1 CELLS; ANIMALS; CELL PROLIFERATION; FURIN; HEK293 CELLS; HELA CELLS; HUMANS; IMMUNOBLOTTING; INSULIN-LIKE GROWTH FACTOR II; MICE; PROPROTEIN CONVERTASES; REAL-TIME POLYMERASE CHAIN REACTION; RECEPTOR, INSULIN; SERINE ENDOPEPTIDASES;

EID: 84921880502     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M114.592543     Document Type: Article

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