Cleavage site mutants of the subtype B insulin receptor are uncleaved and fully functional

Molecular and Cellular Endocrinology

Volumn 128, Issue 1-2, 1997, Pages 129-137

  Auzan, C ^a   Debant, A ^a   Rossi, B ^a   Clauser, E ^a  

^a INSERM   (France)

Author keywords

Autophosphorylation; Cleavage; DNA synthesis; Insulin receptor; Proreceptor; Site directed mutagenesis; Tyrosine kinase

Indexed keywords

CELL SURFACE RECEPTOR; COMPLEMENTARY DNA; INSULIN; INSULIN RECEPTOR; MUTANT PROTEIN; PROTEIN PRECURSOR; PROTEIN TYROSINE KINASE; RECEPTOR SUBTYPE;

AMINO ACID SEQUENCE; ANIMAL CELL; ARTICLE; CHO CELL; CONTROLLED STUDY; ENZYME ACTIVATION; HORMONE RECEPTOR INTERACTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; PROTEIN PROCESSING; RECEPTOR AFFINITY; SITE DIRECTED MUTAGENESIS; STRUCTURE ACTIVITY RELATION;

AMINO ACID SEQUENCE; ANIMALS; BASE SEQUENCE; CHO CELLS; CRICETINAE; DNA; EXONS; HUMANS; INSULIN; KINETICS; MACROMOLECULAR SUBSTANCES; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; RECEPTOR, INSULIN; RECOMBINANT PROTEINS; TRANSFECTION;

EID: 0030887714     PISSN: 03037207     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0303-7207(97)04024-0     Document Type: Article

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