Comparative hepatoprotective effects of tocotrienol analogs against drug-induced liver injury

Redox Biology

Volumn 4, Issue , 2015, Pages 308-320

  Tan, Cheau Yih ^a   Saw, Tzuen Yih ^b   Fong, Chee Wai ^b   Ho, Han Kiat ^a  

^a NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

^b Davos Life Science   (Singapore)

Author keywords

Antioxidant; Drug induced liver injury; Tocopherol; Tocotrienol

Indexed keywords

ALPHA TOCOPHEROL; ALPHA TOCOTRIENOL; BETA TOCOTRIENOL; CASPASE 3; CYCLINE; GAMMA TOCOTRIENOL; GLUTATHIONE; HEME OXYGENASE 1; HYDROGEN PEROXIDE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 6; MALONALDEHYDE; PARACETAMOL; PROTEIN BCL XL; REACTIVE OXYGEN METABOLITE; TOCOPHEROL DERIVATIVE; TRANSCRIPTION FACTOR NRF2; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; ANTIOXIDANT; BCL2L1 PROTEIN, MOUSE; INTERLEUKIN-6, MOUSE; NOS2 PROTEIN, MOUSE; PROTECTIVE AGENT; PROTEIN BCL X; TOCOPHEROL; TUMOR NECROSIS FACTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ANTIOXIDANT ACTIVITY; APOPTOSIS; ARTICLE; BCL XL GENE; CELL VIABILITY; COMPARATIVE EFFECTIVENESS; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG POTENCY; ENZYME ACTIVITY; ENZYME INHIBITION; GENE OVEREXPRESSION; HO 1 GENE; IN VITRO STUDY; LIPID PEROXIDATION; LIVER PROTECTION; LIVER REGENERATION; MITOCHONDRIAL PERMEABILITY; MOUSE; NONHUMAN; NRF 2 GENE; OXIDATIVE STRESS; PROTEIN EXPRESSION; TOXIC HEPATITIS; TOXICITY TESTING; ANIMAL; ANTAGONISTS AND INHIBITORS; CELL SURVIVAL; COMPARATIVE STUDY; CYTOLOGY; DRUG EFFECTS; GENE EXPRESSION REGULATION; GENETICS; LIVER CELL; METABOLISM; MITOCHONDRION; SIGNAL TRANSDUCTION; TRANSFORMED CELL LINE;

ACETAMINOPHEN; ANIMALS; ANTIOXIDANTS; BCL-X PROTEIN; CASPASE 3; CELL LINE, TRANSFORMED; CELL SURVIVAL; GENE EXPRESSION REGULATION; HEPATOCYTES; HYDROGEN PEROXIDE; INTERLEUKIN-6; LIPID PEROXIDATION; MICE; MITOCHONDRIA; NITRIC OXIDE SYNTHASE TYPE II; OXIDATIVE STRESS; PROLIFERATING CELL NUCLEAR ANTIGEN; PROTECTIVE AGENTS; REACTIVE OXYGEN SPECIES; SIGNAL TRANSDUCTION; TOCOPHEROLS; TUMOR NECROSIS FACTOR-ALPHA; VITAMIN E;

EID: 84921874747     PISSN: 22132317     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.redox.2015.01.013     Document Type: Article

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