Characterization of cellular uptake and distribution of vitamin E

Annals of the New York Academy of Sciences

Volumn 1031, Issue , 2004, Pages 368-375

  Saito, Yoshiro ^a   Yoshida, Yasukazu ^a   Nishio, Keiko ^a   Hayakawa, Mieko ^a   Niki, Etsuo ^a  

^a NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY AIST   (Japan)

Author keywords

Antioxidant; Cellular uptake; Oxidative stress; Tocotrienol; Vitamin E

Indexed keywords

ALPHA TOCOPHEROL; ALPHA TOCOTRIENOL; ANTIOXIDANT; LIPID; PEROXIDE; TOCOPHEROL DERIVATIVE;

ANTIOXIDANT ACTIVITY; CELL ASSAY; CELL DEATH; CELL FRACTIONATION; CELL LEVEL; CELL PROTECTION; CELL VIABILITY; CELLULAR DISTRIBUTION; CONFERENCE PAPER; CONTROLLED STUDY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN CELL; INTERNALIZATION; OXIDATIVE STRESS; SELENIUM DEFICIENCY;

EID: 14944378085     PISSN: 00778923     EISSN: None     Source Type: Book Series    
DOI: 10.1196/annals.1331.047     Document Type: Conference Paper

References (16)

1. PACKER, L., S.U. WEBER & G. RIMBACH. 2001. Molecular aspects of alpha-tocotrienol antioxidant action and cell signalling. J. Nutr. 131: 369S-373S.
2. BRIGELIUS-FLOHE, R. & M.G. TRABER. 1999. Vitamin E: function and metabolism. FASEB J. 13: 1145-1155.
3. BLATT, D.H., S.W. LEONARD & M.G. TRABER. 2001. Vitamin E kinetics and the function of tocopherol regulatory proteins. Nutrition 17: 799-805.
4. CHAO, J.T., A. GAPOR & A. THERIAULT. 2002. Inhibitory effect of delta-tocotrienol, a HMG CoA reductase inhibitor, on monocyte-endothelial cell adhesion. J. Nutr. Sci. Vitaminol. (Tokyo) 48: 332-337.
5. NOGUCHI, N., R. HANYU, A. NONAKA, et al. 2003. Inhibition of THP-1 cell adhesion to endothelial cells by alpha-tocopherol and alpha-tocotrienol is dependent on intracellular concentration of the antioxidants. Free Radic. Biol. Med. 34: 1614-1620.
6. KHANNA, S., S. ROY, H. RYU, et al. 2003. Molecular basis of vitamin E action: tocotrienol modulates 12-lipoxygenase, a key mediator of glutamate-induced neurodegeneration. J. Biol. Chem. 278: 43508-43515.
7. SAITO, Y., Y. YOSHIDA, T. AKAZAWA, et al. 2003. Cell death caused by selenium deficiency and protective effect of antioxidants. J. Biol. Chem. 278: 39428-39434.
8. SAITO, Y. & K. TAKAHASHI. 2002. Characterization of selenoprotein P as a selenium supply protein. Eur. J. Biochem. 269: 5746-5751.
9. YOSHIDA, Y., N. ITO, S. SHIMAKAWA, et al. 2003. Susceptibility of plasma lipids to peroxidation. Biochem. Biophys. Res. Commun. 305: 747-753.
10. DE DUVE, C., B.C. PRESSMAN, R. GIANETTO, et al. 1955. Tissue fractionation studies. 6. Intracellular distribution patterns of enzymes in rat-liver tissue. Biochem. J. 60: 604-617.
11. IMAI, H., K. NARASHIMA, M. ARAI, et al. 1998. Suppression of leukotriene formation in RBL-2H3 cells that overexpressed phospholipid hydroperoxide glutathione peroxidase. J. Biol. Chem. 273: 1990-1997.
12. OGASAWARA, M., K. TSURUTA & S. ARAO. 2002. Flame photometric detector for thin-layer chromatography. J. Chromatogr. A 973: 151-158.
13. YOSHIDA, Y., E. NIKI & N. NOGUCHI. 2003. Comparative study on the action of tocopherols and tocotrienols as antioxidant: chemical and physical effects. Chem. Phys. Lipids 123: 63-75.
14. LEIST, M., B. RAAB, S. MAURER, et al. 1996. Conventional cell culture media do not adequately supply cells with antioxidants and thus facilitate peroxide-induced genotoxicity. Free Radic. Biol. Med. 21: 297-306.
15. YOSHIDA, Y., N. NOGUCHI, A. WATANABE, et al. 2002. Antioxidant action of 2,2,4,6-tetra-substituted 2,3-dihydro-5-hydroxybenzofuran against lipid peroxidation: effects of substituents and side chain. Free Radic. Res. 36: 1171-1178.
16. SUARNA, C., R.L. HOOD, R.T. DEAN, et al. 1993. Comparative antioxidant activity of tocotrienols and other natural lipid-soluble antioxidants in a homogeneous system, and in rat and human lipoproteins. Biochim. Biophys. Acta. 1166: 163-170.