Adenosine through the A2A adenosine receptor increases IL-1β in the brain contributing to anxiety

Brain, Behavior, and Immunity

Volumn 41, Issue 1, 2014, Pages 218-231

  Chiu, Gabriel S ^a   Darmody, Patrick T ^a   Walsh, John P ^a   Moon, Morgan L ^a   Kwakwa, Kristin A ^a   Bray, Julie K ^a   McCusker, Robert H ^a   Freund, Gregory G ^a  

^a UNIVERSITY OF ILLINOIS AT URBANA CHAMPAIGN   (United States)

Author keywords

Adenosine receptor; Anxiety; Caspase 1; Interleukin 1

Indexed keywords

ADENOSINE; ADENOSINE A2A RECEPTOR; ADENOSINE TRIPHOSPHATE SENSITIVE POTASSIUM CHANNEL; CYCLIC AMP; CYCLIC AMP DEPENDENT PROTEIN KINASE; GLIBENCLAMIDE; INTERLEUKIN 1 RECEPTOR ASSOCIATED KINASE 1; INTERLEUKIN 1 RECEPTOR TYPE I; INTERLEUKIN 1BETA; INTERLEUKIN 1BETA CONVERTING ENZYME; KT 5720; MESSENGER RNA; POTASSIUM CHANNEL; CARBAZOLE DERIVATIVE; IL1B PROTEIN, MOUSE; IL1R1 PROTEIN, MOUSE; NERVE PROTEIN; POTASSIUM; PYRROLE DERIVATIVE;

ADULT; AMYGDALOID NUCLEUS; ANIMAL EXPERIMENT; ANIMAL TISSUE; ANXIETY DISORDER; ARTICLE; BRAIN LEVEL; CONTROLLED STUDY; DRUG ANTAGONISM; ENZYME ACTIVATION; ENZYME ACTIVITY; FOOD INTAKE; GENE EXPRESSION; GENE SILENCING; GENOTYPE; HIPPOCAMPUS; LOCOMOTION; MALE; MOUSE; NONHUMAN; OPEN FIELD TEST; POTASSIUM TRANSPORT; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; WILD TYPE; ANIMAL; ANXIETY; BAGG ALBINO MOUSE; BIOSYNTHESIS; BRAIN; C57BL MOUSE; CHEMICALLY INDUCED; DEFICIENCY; DRUG EFFECTS; EXPLORATORY BEHAVIOR; FEEDING BEHAVIOR; GENETICS; ION TRANSPORT; KNOCKOUT MOUSE; MAZE TEST; METABOLISM; PATHOPHYSIOLOGY; PHYSIOLOGY;

ADENOSINE; AMYGDALA; ANIMALS; ANXIETY; BRAIN; CARBAZOLES; CASPASE 1; CYCLIC AMP-DEPENDENT PROTEIN KINASES; ENZYME ACTIVATION; EXPLORATORY BEHAVIOR; FEEDING BEHAVIOR; GLYBURIDE; INTERLEUKIN-1BETA; ION TRANSPORT; KATP CHANNELS; LOCOMOTION; MAZE LEARNING; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; MICE, KNOCKOUT; NERVE TISSUE PROTEINS; POTASSIUM; PYRROLES; RECEPTOR, ADENOSINE A2A; RECEPTORS, INTERLEUKIN-1 TYPE I;

EID: 84921853105     PISSN: 08891591     EISSN: 10902139     Source Type: Journal    
DOI: 10.1016/j.bbi.2014.05.018     Document Type: Article

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