메뉴 건너뛰기




Volumn 16, Issue 2, 2015, Pages 2559-2573

Sinomenine hydrochloride protects against polymicrobial sepsis via autophagy

Author keywords

Autophagy; Cecal ligation and puncture (CLP); Peritoneal macrophages (PM); Sepsis; Sinomenine hydrochloride (SIN HCl)

Indexed keywords

3 METHYLADENINE; ALANINE AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE; CREATININE; CYTOKINE; INTERLEUKIN 6; MEMBRANE PROTEIN; MICROTUBULE ASSOCIATED PROTEIN LIGHT CHAIN 3; SINOMENINE; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; 3-METHYLADENINE; ADENINE; LIPOPOLYSACCHARIDE; MICROTUBULE ASSOCIATED PROTEIN; MORPHINAN DERIVATIVE;

EID: 84921845273     PISSN: 16616596     EISSN: 14220067     Source Type: Journal    
DOI: 10.3390/ijms16022559     Document Type: Article
Times cited : (57)

References (34)
  • 1
    • 0037426726 scopus 로고    scopus 로고
    • The pathophysiology and treatment of sepsis
    • Hotchkiss, R.S.; Karl, I.E. The pathophysiology and treatment of sepsis. N. Engl. J. Med. 2003, 348, 138-150.
    • (2003) N. Engl. J. Med , vol.348 , pp. 138-150
    • Hotchkiss, R.S.1    Karl, I.E.2
  • 2
    • 0038578608 scopus 로고    scopus 로고
    • Novel strategies for the treatment of sepsis
    • Riedemann, N.C.; Guo, R.F.; Ward, P.A. Novel strategies for the treatment of sepsis. Nat. Med. 2003, 9, 517-524.
    • (2003) Nat. Med , vol.9 , pp. 517-524
    • Riedemann, N.C.1    Guo, R.F.2    Ward, P.A.3
  • 3
    • 1842583789 scopus 로고    scopus 로고
    • Development by self-digestion: Molecular mechanisms and biological functions of autophagy
    • Levine, B.; Klionsky, D.J. Development by self-digestion: Molecular mechanisms and biological functions of autophagy. Dev. Cell 2004, 6, 463-477.
    • (2004) Dev. Cell , vol.6 , pp. 463-477
    • Levine, B.1    Klionsky, D.J.2
  • 4
    • 77956416339 scopus 로고    scopus 로고
    • Autophagy in mammalian development and differentiation
    • Mizushima, N.; Levine, B. Autophagy in mammalian development and differentiation. Nat. Cell Biol. 2010, 12, 823-830.
    • (2010) Nat. Cell Biol , vol.12 , pp. 823-830
    • Mizushima, N.1    Levine, B.2
  • 8
    • 84872298070 scopus 로고    scopus 로고
    • Lc3 over-expression improves survival and attenuates lung injury through increasing autophagosomal clearance in septic mice
    • Lo, S.; Yuan, S.S.; Hsu, C.; Cheng Y.J.; Chang, Y.F.; Hsueh, H.W.; Lee, P.H.; Hsieh, Y.C. Lc3 over-expression improves survival and attenuates lung injury through increasing autophagosomal clearance in septic mice. Ann. Surg. 2013, 257, 352-363.
    • (2013) Ann. Surg , vol.257 , pp. 352-363
    • Lo, S.1    Yuan, S.S.2    Hsu, C.3    Cheng, Y.J.4    Chang, Y.F.5    Hsueh, H.W.6    Lee, P.H.7    Hsieh, Y.C.8
  • 9
    • 79957499768 scopus 로고    scopus 로고
    • Complete induction of autophagy is essential for cardioprotection in sepsis
    • Hsieh, C.H; Pai, P.Y.; Hsueh, H.W.; Yuan, S.S; Hsieh, Y.C. Complete induction of autophagy is essential for cardioprotection in sepsis. Ann. Surg. 2011, 253, 1190-1200.
    • (2011) Ann. Surg , vol.253 , pp. 1190-1200
    • Hsieh, C.H.1    Pai, P.Y.2    Hsueh, H.W.3    Yuan, S.S.4    Hsieh, Y.C.5
  • 10
    • 79955526958 scopus 로고    scopus 로고
    • Suppression of autophagy in rat liver at late stage of polymicrobial sepsis
    • Chien, W.S.; Chen, Y.H.; Chiang, P.C.; Hsiao, H.W.; Chuang, S.M.; Lue, S.I.; Hsu, C. Suppression of autophagy in rat liver at late stage of polymicrobial sepsis. Shock 2011, 35, 506-511.
    • (2011) Shock , vol.35 , pp. 506-511
    • Chien, W.S.1    Chen, Y.H.2    Chiang, P.C.3    Hsiao, H.W.4    Chuang, S.M.5    Lue, S.I.6    Hsu, C.7
  • 11
    • 84894472702 scopus 로고    scopus 로고
    • Complete activation of autophagic process attenuates liver injury and improves survival in septic mice
    • Lin, C.W.; Lo, S; Perng, D.S.; Wu, D.B.; Lee, P.H.; Chang, Y.F.; Kuo, P.L.; Yu, M.L.; Yuan, S.S.; Hsieh, Y.C. Complete activation of autophagic process attenuates liver injury and improves survival in septic mice. Shock 2014, 41, 241-249.
    • (2014) Shock , vol.41 , pp. 241-249
    • Lin, C.W.1    Lo, S.2    Perng, D.S.3    Wu, D.B.4    Lee, P.H.5    Chang, Y.F.6    Kuo, P.L.7    Yu, M.L.8    Yuan, S.S.9    Hsieh, Y.C.10
  • 12
    • 84863229562 scopus 로고    scopus 로고
    • The decline of autophagy contributes to proximal tubular dysfunction during sepsis
    • Hsiao, H.W.; Tsai, K.L.; Wang, L.F.; Chen, Y.H.; Chiang, P.C.; Chuang, S.M.; Hsu, C. The decline of autophagy contributes to proximal tubular dysfunction during sepsis. Shock 2012, 37, 289-296.
    • (2012) Shock , vol.37 , pp. 289-296
    • Hsiao, H.W.1    Tsai, K.L.2    Wang, L.F.3    Chen, Y.H.4    Chiang, P.C.5    Chuang, S.M.6    Hsu, C.7
  • 13
    • 54249103265 scopus 로고    scopus 로고
    • Sinomenine versus NSAIDs for the treatment of rheumatoid arthritis: A systematic review and meta-analysis
    • Xu, M.; Liu, L.; Qi, C.; Deng, B.; Cai, X. Sinomenine versus NSAIDs for the treatment of rheumatoid arthritis: A systematic review and meta-analysis. Planta Med. 2008, 74, 1423-1429.
    • (2008) Planta Med. , vol.74 , pp. 1423-1429
    • Xu, M.1    Liu, L.2    Qi, C.3    Deng, B.4    Cai, X.5
  • 14
    • 0017115289 scopus 로고
    • Pharmacology of sinomenine, an anti-rheumatic alkaloid from Sinomenium acutum
    • Yamasaki, H. Pharmacology of sinomenine, an anti-rheumatic alkaloid from Sinomenium acutum. Acta Med. Okayama 1976, 30, 1-20.
    • (1976) Acta Med. Okayama , vol.30 , pp. 1-20
    • Yamasaki, H.1
  • 15
    • 14844320581 scopus 로고    scopus 로고
    • Effect of sinomenine on cytokine expression of macrophages and synoviocytes in adjuvant arthritis rats
    • Wang, Y.; Fang, Y.; Huang, W.; Zhou, X.; Wang, M.; Zhong, B.; Peng, D. Effect of sinomenine on cytokine expression of macrophages and synoviocytes in adjuvant arthritis rats. J. Ethnopharmacol. 2005, 98, 37-43.
    • (2005) J. Ethnopharmacol , vol.98 , pp. 37-43
    • Wang, Y.1    Fang, Y.2    Huang, W.3    Zhou, X.4    Wang, M.5    Zhong, B.6    Peng, D.7
  • 16
    • 15744402274 scopus 로고    scopus 로고
    • Requirement for ERK activation in sinomenine-i, nduced apoptosis of macrophages
    • He, X.; Wang, J.; Guo, Z.; Liu, Q.; Chen, T.; Wang, X.; Cao, X. Requirement for ERK activation in sinomenine-i, nduced apoptosis of macrophages. Immunol. Lett. 2005, 98, 91-96.
    • (2005) Immunol. Lett , vol.98 , pp. 91-96
    • He, X.1    Wang, J.2    Guo, Z.3    Liu, Q.4    Chen, T.5    Wang, X.6    Cao, X.7
  • 20
  • 21
    • 84876406503 scopus 로고    scopus 로고
    • Enhancing autophagy with activated protein C and rapamycin protects against sepsis-induced acute lung injury
    • Yen, Y.T.; Yang, H.R.; Lo, H.C.; Hsieh, Y.C.; Tsai, S.C.; Hong, C.W.; Hsieh, C.H. Enhancing autophagy with activated protein C and rapamycin protects against sepsis-induced acute lung injury. Surgery 2013, 153, 689-698.
    • (2013) Surgery , vol.153 , pp. 689-698
    • Yen, Y.T.1    Yang, H.R.2    Lo, H.C.3    Hsieh, Y.C.4    Tsai, S.C.5    Hong, C.W.6    Hsieh, C.H.7
  • 25
    • 0005677775 scopus 로고
    • 3-Methyladenine: Specific inhibitor of autophagic/lysosomal protein degradation in isolated rat hepatocytes
    • Seglen, P.O.; Gordon, P.B. 3-Methyladenine: Specific inhibitor of autophagic/lysosomal protein degradation in isolated rat hepatocytes. Proc. Natl. Acad. Sci. USA 1982, 79, 1889-1892.
    • (1982) Proc. Natl. Acad. Sci. USA , vol.79 , pp. 1889-1892
    • Seglen, P.O.1    Gordon, P.B.2
  • 26
    • 84889636204 scopus 로고    scopus 로고
    • Autophagy in the immune system
    • Puleston, D.J.; Simon, A.K. Autophagy in the immune system. Immunology 2014, 141, 1-8.
    • (2014) Immunology , vol.141 , pp. 1-8
    • Puleston, D.J.1    Simon, A.K.2
  • 27
    • 84882712453 scopus 로고    scopus 로고
    • Autophagy and cellular immune responses
    • Ma, Y.; Galluzzi L.; Zitvogel, L.; Kroemer, G. Autophagy and cellular immune responses. Immunity 2013, 39, 211-227.
    • (2013) Immunity , vol.39 , pp. 211-227
    • Ma, Y.1    Galluzzi, L.2    Zitvogel, L.3    Kroemer, G.4
  • 28
    • 61449154547 scopus 로고    scopus 로고
    • Immunodesign of experimental sepsis by cecal ligation and puncture
    • Rittirsch, D.; Huber-Lang, M.S.; Flierl, M.A.; Ward, P.A. Immunodesign of experimental sepsis by cecal ligation and puncture. Nat. Protoc. 2009, 4, 31-36.
    • (2009) Nat. Protoc , vol.4 , pp. 31-36
    • Rittirsch, D.1    Huber-Lang, M.S.2    Flierl, M.A.3    Ward, P.A.4
  • 29
    • 84865132025 scopus 로고    scopus 로고
    • Use of blood urea nitrogen, creatinine, interleukin-6, granulocyte-macrophage colony stimulating factor in combination to predict the severity and outcome of abdominal sepsis in rats
    • Gao, M.; Zhang, L.; Liu, Y.; Yang, M.; Wang, N.; Wang, K.; Ou, D.; Liu, M.; Chen, G.; Liu, K.; Xiao, X. Use of blood urea nitrogen, creatinine, interleukin-6, granulocyte-macrophage colony stimulating factor in combination to predict the severity and outcome of abdominal sepsis in rats. Inflamm. Res. 2012, 61, 889-897.
    • (2012) Inflamm. Res , vol.61 , pp. 889-897
    • Gao, M.1    Zhang, L.2    Liu, Y.3    Yang, M.4    Wang, N.5    Wang, K.6    Ou, D.7    Liu, M.8    Chen, G.9    Liu, K.10    Xiao, X.11
  • 30
    • 0030732391 scopus 로고    scopus 로고
    • Prolonged partial liquid ventilation using conventional and high-frequency ventilatory techniques: Gas exchange and lung pathology in an animal model of respiratory distress syndrome
    • Smith, K.M.; Mrozek, J.D.; Simonton, S.C.; Bing, D.R.; Meyers, P.A.; Connett, J.E.; Mammel, M.C. Prolonged partial liquid ventilation using conventional and high-frequency ventilatory techniques: Gas exchange and lung pathology in an animal model of respiratory distress syndrome. Crit. Care Med. 1997, 25, 1888-1897.
    • (1997) Crit. Care Med , vol.25 , pp. 1888-1897
    • Smith, K.M.1    Mrozek, J.D.2    Simonton, S.C.3    Bing, D.R.4    Meyers, P.A.5    Connett, J.E.6    Mammel, M.C.7
  • 32
    • 33646519915 scopus 로고    scopus 로고
    • Simvastatin improves sepsis-induced mortality and acute kidney injury via renal vascular effects
    • Yasuda, H.; Yuen, P.S.; Hu, X.; Zhou, H.; Star, R.A. Simvastatin improves sepsis-induced mortality and acute kidney injury via renal vascular effects. Kidney Int. 2006, 69, 1535-1542.
    • (2006) Kidney Int , vol.69 , pp. 1535-1542
    • Yasuda, H.1    Yuen, P.S.2    Hu, X.3    Zhou, H.4    Star, R.A.5
  • 33
    • 84925933243 scopus 로고    scopus 로고
    • HSF-1 is involved in attenuating the release of inflammatory cytokines induced by LPS through regulating autophagy
    • Tong, Z.; Jiang, B.; Zhang, L.; Liu, Y.; Gao, M.; Jiang, Y; Li, Y.; Lu, Q.; Yao, Y.; Xiao, X. HSF-1 is involved in attenuating the release of inflammatory cytokines induced by LPS through regulating autophagy. Shock 2014, 41, 449-453.
    • (2014) Shock , vol.41 , pp. 449-453
    • Tong, Z.1    Jiang, B.2    Zhang, L.3    Liu, Y.4    Gao, M.5    Jiang, Y.6    Li, Y.7    Lu, Q.8    Yao, Y.9    Xiao, X.10


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.