Autophagy-related IRGM polymorphism is associated with mortality of patients with severe sepsis

PLoS ONE

Volumn 9, Issue 3, 2014, Pages

  Kimura, Tomonori ^a   Watanabe, Eizo ^a   Sakamoto, Teruo ^b   Takasu, Osamu ^b   Ikeda, Toshiaki ^c   Ikeda, Kazumi ^c   Kotani, Joji ^d   Kitamura, Nobuya ^e   Sadahiro, Tomohito ^a   Tateishi, Yoshihisa ^a   Shinozaki, Koichiro ^a   Oda, Shigeto ^a  

^a CHIBA UNIVERSITY   (Japan)

^b KURUME UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^c TOKYO MEDICAL UNIVERSITY HACHIOJI MEDICAL CENTER   (Japan)

^d HYOGO COLLEGE OF MEDICINE   (Japan)

^e KIMITSU CHUO HOSPITAL   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOSINE; LIPOPOLYSACCHARIDE; MESSENGER RNA; THYMINE; GUANINE NUCLEOTIDE BINDING PROTEIN; IRGM PROTEIN, HUMAN;

ADULT; AGED; ARTICLE; AUTOPHAGY; COHORT ANALYSIS; DISEASE SEVERITY; FEMALE; GENE; GENETIC CODE; GENOTYPE; HOMOZYGOTE; HOSPITAL ADMISSION; HUMAN; INFORMED CONSENT; INTENSIVE CARE UNIT; IRGM GENE; JAPAN; JAPANESE; MAJOR CLINICAL STUDY; MALE; MORTALITY; POLYMORPHIC LOCUS; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; SEPSIS; SEPTIC SHOCK; SINGLE NUCLEOTIDE POLYMORPHISM; UNIVERSITY HOSPITAL; VOLUNTEER; CELL SURVIVAL; CHEMISTRY; GENETIC POLYMORPHISM; GENETICS; INFLAMMATION; INNATE IMMUNITY; MICROBIOLOGY; MIDDLE AGED; MYCOBACTERIUM TUBERCULOSIS; TREATMENT OUTCOME;

AGED; AUTOPHAGY; CELL SURVIVAL; COHORT STUDIES; FEMALE; GENOTYPE; GTP-BINDING PROTEINS; HOMOZYGOTE; HUMANS; IMMUNITY, INNATE; INFLAMMATION; JAPAN; LIPOPOLYSACCHARIDES; MALE; MIDDLE AGED; MYCOBACTERIUM TUBERCULOSIS; POLYMORPHISM, GENETIC; POLYMORPHISM, SINGLE NUCLEOTIDE; SEPSIS; TREATMENT OUTCOME;

EID: 84898745055     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0091522     Document Type: Article

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