Systematical analysis of cutaneous squamous cell carcinoma network of microRNAs, transcription factors, and target and host genes

Asian Pacific Journal of Cancer Prevention

Volumn 15, Issue 23, 2014, Pages 10355-10361

  Wang, Ning ^a   Xu, Zhi Wen ^a   Wang, Kun Hao ^a  

^a JILIN UNIVERSITY   (China)

Author keywords

Cutaneous squamous cell carcinoma; miRNAs; Signalling networks; Transcription factors

Indexed keywords

ARGONAUTE PROTEIN; COLLAGENASE 3; EIF2C2 PROTEIN, HUMAN; FGFR3 PROTEIN, HUMAN; FIBROBLAST GROWTH FACTOR RECEPTOR 3; MICRORNA; MMP13 PROTEIN, HUMAN; PROTEIN P53; TP53 PROTEIN, HUMAN; TRANSCRIPTION FACTOR;

GENE EXPRESSION REGULATION; GENETICS; HUMAN; METABOLISM; SIGNAL TRANSDUCTION; SKIN TUMOR; SQUAMOUS CELL CARCINOMA;

ARGONAUTE PROTEINS; CARCINOMA, SQUAMOUS CELL; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; MATRIX METALLOPROTEINASE 13; MICRORNAS; RECEPTOR, FIBROBLAST GROWTH FACTOR, TYPE 3; SIGNAL TRANSDUCTION; SKIN NEOPLASMS; TRANSCRIPTION FACTORS; TUMOR SUPPRESSOR PROTEIN P53;

EID: 84921777934     PISSN: 15137368     EISSN: None     Source Type: Journal    
DOI: 10.7314/APJCP.2014.15.23.10355     Document Type: Article

References (72)

1. Abdel-Rahman WM, Ruosaari S, Knuutila S et al (2012). Differential roles of EPS8 in carcinogenesis: Loss of protein expression in a subset of colorectal carcinoma and adenoma. WJG, 18, 3896-903.
2. Arroyo JD, Chevillet JR, Kroh EM et al (2011). Argonaute2 complexes carry a population of circulating microRNAs independent of vesicles in human plasma. PNAS, 108, 5003-8.
3. Baskerville S, Bartel DP (2005). Microarray profiling of microRNAs reveals frequent coexpression with neighboring miRNAs and host genes. RNA, 11, 241-7.
4. Belkin DA, Mitsui H, Wang CQ et al (2013). CD200 Upregulation in Vascular Endothelium Surrounding Cutaneous Squamous Cell Carcinoma. JAMA Dermatol, 149, 178-86.
5. Botti E, Spallone G, Moretti F et al (2011). Developmental factor IRF6 exhibits tumor suppressor activity in squamous cell carcinomas. PNAS, 108, 13710-5.
6. Boukamp P (2005). Non-melanoma skin cancer: what drives tumor development and progression?. Carcinogenesis, 26, 1657-67.
7. Bruegger C, Kempf W, Spoerri I et al (2013). MicroRNA expression differs in cutaneous squamous cell carcinomas and healthy skin of immunocompetent individuals. Exp Dermatol, 22, 426-8.
8. Butani A, Arbesfeld DM, Schwartz RA (2005). Premalignant and early squamous cell carcinoma. Clin Plast Surg, 32, 223.
9. Calin GA, Croce CM (2006). MicroRNA signatures in human cancers. Nat Rev Cancer, 6, 857-66.
10. Cao G, Huang B, Liu Z et al (2010). Intronic miR-301 feedback regulates its host gene, ska2, in A549 cells by targeting MEOX2 to affect ERK/CREB pathways. Biochem Bioph Res Co, 396, 978-82.
11. Chakraborty S, Swanson BJ, Bonthu N et al (2010). Aberrant upregulation of MUC4 mucin expression in cutaneous condyloma acuminatum and squamous cell carcinoma suggests a potential role in the diagnosis and therapy of skin diseases. J Clin Pathol, 63, 579-84.
12. Chang SS, Smith I, Glazer C et al (2010). EIF2C Is Overexpressed and Amplified in Head and Neck Squamous Cell Carcinoma. Orl J Oto-Rhino-Lary, 72, 337-43.
13. Chakraborty S, Swanson BJ, Bonthu N et al (2012). Differential expression of Fas family members and Bcl-2 family members in benign versus malignant epithelial ovarian cancer (EOC) in North Indian population. Mol Cell Biochem, 368, 119-26.
14. Chen YJ, Wu CY, Chang CC et al (2008). Nuclear Kruppel-like factor 4 expression is associated with human skin squamous cell carcinoma progression and metastasis. Cancer Biol Ther, 7, 777-82.
15. Croce CM (2009). Causes and consequences of microRNA dysregulation in cancer. Nat Rev Genet, 10, 704-14.
16. Dang C, Gottschling M, Manning K et al (2006). Identification of dysregulated genes in cutaneous squamous cell carcinoma. Oncol Rep, 16, 513-9.
17. Das GD, Bhattacharjee B, Sen S et al (2012). Some novel insights on HPV16 related cervical cancer pathogenesis based on analyses of LCR methylation, viral load, E7 and E2/E4 expressions. Plos One, 7, 44678.
18. Endo-Munoz L, Dahler A, Teakle N et al (2009). E2F7 can regulate proliferation, differentiation, and apoptotic responses in human keratinocytes: implications for cutaneous squamous cell carcinoma formation. Cancer Res, 69, 1800-8.
19. Enerly E, Steinfeld I, Kleivi K et al (2011). miRNA-mRNA integrated analysis reveals roles for miRNAs in primary breast tumors. Plos One, 6, 16915.
20. Griewank KG, Murali R, Schilling B et al (2013). TERT promoter mutations are frequent in cutaneous basal cell carcinoma and squamous cell carcinoma. Plos One, 8, 80354.
21. Hameetman L, Commandeur S, Bavinck JN et al (2013). Molecular profiling of cutaneous squamous cell carcinomas and actinic keratoses from organ transplant recipients. BMC Cancer, 13, 58.
22. Heah KG1, Hassan MI, Huat SC (2011). p53 Expression as a Marker of Microinvasion in Oral Squamous Cell Carcinoma. Asian Pac J Cancer P, 12, 1017-22.
23. Hsu SD, Lin FM, Wu WY et al (2011). Hsu SD, Lin FM, Wu WY et al: miRTarBase: a database curates experimentally validated microRNA-target interactions. Nucleic Acids Res, 39, 163-9.
24. Huber MA, Kraut N, Beug H (2005). Molecular requirements for epithelial-mesenchymal transition during tumor progression. Curr Opin Cell Biol, 17, 548-58.
25. Inui M, Martello G, Piccolo S (2010). MicroRNA control of signal transduction. Nat Rev Mol Cell Bio, 11, 252-63.
26. Iorio MV, Ferracin M, Liu CG et al (2005). MicroRNA gene expression deregulation in human breast cancer. Cancer Res, 65, 7065-70.
27. Johnson SM, Grosshans H, Shingara J et al (2005). RAS is regulated by the let-7 microRNA family. Cell, 120, 635-47.
28. Karin M (1990). Too many transcription factors: positive and negative interactions. New Biol, 2, 126-31.
29. Kathpalia VP, Mussak EN, Chow SS et al (2006). Genome-wide transcriptional profiling in human squamous cell carcinoma of the skin identifies unique tumor-associated signatures. J Dermatol, 33, 309-18.
30. Kim SW, Ramasamy K, Bouamar H et al (2012). MicroRNAs miR-125a and miR-125b constitutively activate the NF-kappa B pathway by targeting the tumor necrosis factor alpha-induced protein 3 (TNFAIP3, A20). PNAS, 109, 7865-70.
31. Kozomara A, Griffiths-Jones S. (2011). miRBase: integrating microRNA annotation and deep-sequencing data. Nucleic Acids Res, 39, 152-7.
32. Latchman DS (1997). Transcription factors: an overview. Int J Biochem Cell Biol, 29, 1305-12.
33. Le MT, Shyh-Chang N, Khaw SL et al (2011). Conserved regulation of p53 network dosage by microRNA-125b occurs through evolving mirna-target gene pairs. Plos Genet, 7, 1002242.
34. Le MT, Teh C, Shyh-Chang N et al (2009). MicroRNA-125b is a novel negative regulator of p53. Gene Dev, 23, 862-76.
35. Lee YS, Kim HK, Chung SM et al (2005). Depletion of human micro-RNA miR-125b reveals that it is critical for the proliferation of differentiated cells but not for the downregulation of putative targets during differentiation. J Biol Chem, 280, 16635-41.
36. Lefort K, Brooks Y, Ostano P et al (2013). A miR-34a-SIRT6 axis in the squamous cell differentiation network. EMBO J, 32, 2248-63.
37. Li Y, Guessous F, Zhang Y et al (2009). MicroRNA-34a inhibits glioblastoma growth by targeting multiple oncogenes. Cancer Res, 69, 7569-76.
38. Libermann TA, Zerbini LF (2006). Targeting transcription factors for cancer gene therapy. Curr Gene Ther, 6, 17-33.
39. Loeb KR, Asgari MM, Hawes SE et al (2012). Analysis of Tp53 codon 72 polymorphisms, Tp53 mutations, and HPV infection in cutaneous squamous cell carcinomas. Plos One, 7, 34422.
40. Lu J, Getz G, Miska EA et al (2005). MicroRNA expression profiles classify human cancers. Nature, 435, 834-8.
41. Mandinova A, Kolev V, Neel V, et al (2009). A positive FGFR3/FOXN1 feedback loop underlies benign skin keratosis versus squamous cell carcinoma formation in humans. J Clin Invest, 119, 3127-37.
42. Michael MZ, O' Connor SM, van Holst Pellekaan NG et al (2003). Reduced accumulation of specific microRNAs in colorectal neoplasia. Mol Cancer Res, 1, 882-91.
43. Moad AI, Tan ML, Kaur G et al (2012). Lack of increased P15INK4B protein expression in basal cell carcinomas. Asian Pac J Cancer Prev, 13, 6239-44.
44. Moad AI, Lan TM, Kaur G, et al (2009). Immunohistochemical determination of the P15 (INK4b) protein expression in cutaneous squamous cell carcinoma. J Cutan Pathol, 36, 183-9.
45. Nam EJ, Yoon H, Kim SW et al (2008). MicroRNA expression profiles in serous ovarian carcinoma. Clin Cancer Res, 14, 2690-5.
46. Park E, Liu B, Xia X et al (2011). Role of IKK alpha in skin squamous cell carcinomas. Future Oncol, 7, 123-34.
47. Petitjean A, Achatz MI, Borresen-Dale AL et al (2007). TP53 mutations in human cancers: functional selection and impact on cancer prognosis and outcomes. Oncogene, 26, 2157-65.
48. Petitjean A, Mathe E, Kato S et al (2007). Impact of mutant p53 functional properties on TP53 mutation patterns and tumor phenotype: Lessons from recent developments in the IARC TP53 database. Hum Mutat, 28, 622-9.
49. Polakis P (2000). Wnt signaling and cancer. Gene Dev, 14, 1837-51.
50. Poliseno L, Salmena L, Riccardi L et al (2010). Identification of the miR-106b∼25 microRNA cluster as a proto-oncogenic PTEN-targeting intron that cooperates with its host gene MCM7 in transformation. Sci Signal, 3, 29.
51. Qu H, Xu W, Huang Y et al (2011). Circulating miRNAs: promising biomarkers of human cancer. Asian Pac J Cancer Prev, 12, 1117-25.
52. Raver-Shapira N, Marciano E, Meiri E et al (2007). Transcriptional activation of miR-34a contributes to p53-mediated apoptosis. Mol Cell, 26, 731-43.
53. Rodriguez A, Griffiths-Jones S, Ashurst JL et al (2004). Identification of mammalian microRNA host genes and transcription units. Genome Res, 14, 1902-10.
54. Sand M, Skrygan M, Georgas D et al (2012). Expression levels of the microRNA maturing microprocessor complex component DGCR8 and the RNA-induced silencing complex (RISC) components argonaute-1, argonaute-2, PACT, TARBP1, and TARBP2 in epithelial skin cancer. Mol Carcinogen, 51, 916-22.
55. Sand M, Skrygan M, Georgas D et al (2012). Microarray analysis of microRNA expression in cutaneous squamous cell carcinoma. J Dermatol Sci, 68, 119-26.
56. Sethupathy P, Corda B, Hatzigeorgiou AG et al (2006). TarBase: A comprehensive database of experimentally supported animal microRNA targets. RNA, 12, 192-7.
57. Soussi T, Beroud C (2001). Assessing TP53 status in human tumours to evaluate clinical outcome. Nat Rev Cancer, 1, 233-40.
58. Sowalsky AG, Alt-Holland A, Shamis Y et al (2010). RalA suppresses early stages of Ras-induced squamous cell carcinoma progression. Oncogene, 29, 45-55.
59. Suzuki HI, Yamagata K, Sugimoto K et al (2009). Modulation of microRNA processing by p53. Nature, 460, 529-111.
60. Toriseva M, Ala-aho R, Peltonen S et al (2012). Keratinocyte Growth Factor Induces Gene Expression Signature Associated with Suppression of Malignant Phenotype of Cutaneous Squamous Carcinoma Cells. Plos One, 7, 33041.
61. Volinia S, Calin GA, Liu CG et al (2006). A microRNA expression signature of human solid tumors defines cancer gene targets. PNAS, 103, 2257-61.
62. Wang J, Lu M, Qiu C et al (2010). TransmiR: a transcription factor-microRNA regulation database. Nucleic Acids Res 38: D119-122, 2010. Nucleic Acids Res, 38, 119-22.
63. Wang NJ, Sanborn Z, Arnett KL et al (2011). Loss-of-function mutations in Notch receptors in cutaneous and lung squamous cell carcinoma. PNAS, 108, 17761-6.
64. Wu Di, Guo Ze, Min Wei et al (2012). Upregulation of TCTP expression in human skin squamous cell carcinoma increases tumor cell viability through anti-apoptotic action of the protein. Exp Ther Med, 3, 437-42.
65. Wu J, Zheng C, Fan Y et al (2014). Downregulation of MicroRNA-30 Facilitates Podocyte Injury and Is Prevented by Glucocorticoids. J Am Soc Nephrol, 25, 92-104.
66. Xia YH, Li M, Fu DD et al (2013). Effects of PTTG down-regulation on proliferation and metastasis of the SCL-1 cutaneous squamous cell carcinoma cell Line. Asian Pac J Cancer Prev, 14, 6245-8.
67. Xie YJ, Long ZF, He XS (2013). Involvement of EBV-encoded BART-miRNAs and dysregulated cellular miRNAs in nasopharyngeal carcinoma genesis. Asian Pac J Cancer Prev, 14, 5637-44.
68. Xu N, Zhang L, Meisgen F et al (2012). MicroRNA-125b Down-regulates Matrix Metallopeptidase 13 and Inhibits Cutaneous Squamous Cell Carcinoma Cell Proliferation, Migration, and Invasion. J Biol Chem, 287, 29899-908.
69. Yadav V, Yanez NC, Fenton SE et al (2010). Loss of protein kinase C delta gene expression in human squamous cell carcinomas-a laser capture microdissection study. Am J Pathol, 176, 1091-6.
70. Yamakuchi M, Lowenstein CJ (2009). MiR-34, SIRT1 and p53 The feedback loop. Cell Cycle, 8, 712-5.
71. Yin VT1, Pfeiffer ML, Esmaeli B (2013). Targeted therapy for orbital and periocular basal cell carcinoma and squamous cell carcinoma. Ophthal Plast Recons, 29, 87-92.
72. Zheng DJ, Yu GH, Gao JF et al (2013). Concomitant EGFR inhibitors combined with radiation for treatment of non-small cell lung carcinoma. Asian Pac J Cancer Prev, 14, 4485-94.