-
1
-
-
84859438743
-
Periocular cutaneous malignancies: A review of the literature
-
Slutsky JB, Jones EC. Periocular cutaneous malignancies: A review of the literature. Dermatol Surg 2012;38:552-69
-
(2012)
Dermatol Surg
, vol.38
, pp. 552-569
-
-
Slutsky, J.B.1
Jones, E.C.2
-
2
-
-
0018694715
-
The basal cell nevus syndrome: Disasters occurring among a series of 36 patients
-
Southwick GJ, Schwartz RA. The basal cell nevus syndrome: Disasters occurring among a series of 36 patients. Cancer 1979;44:2294-305
-
(1979)
Cancer
, vol.44
, pp. 2294-2305
-
-
Southwick, G.J.1
Schwartz, R.A.2
-
3
-
-
83655196814
-
Emerging treatments and signaling pathway inhibitors
-
suppl
-
Tang JY, Marghoob AA. Emerging treatments and signaling pathway inhibitors. Semin Cutan Med Surg 2011;30(4 suppl):S14-8
-
(2011)
Semin Cutan Med Surg
, vol.30
, Issue.4
-
-
Tang, J.Y.1
Marghoob, A.A.2
-
4
-
-
2342492317
-
Review of epidermal growth factor receptor biology
-
Herbst RS. Review of epidermal growth factor receptor biology. Int J Radiat Oncol Biol Phys 2004;59(2 suppl):21-6
-
(2004)
Int J Radiat Oncol Biol Phys
, vol.59
, Issue.SUPPL.
, pp. 21-26
-
-
Herbst, R.S.1
-
6
-
-
15844386165
-
Mutations of the human homolog of Drosophila patched in the nevoid basal cell carcinoma syndrome
-
Hahn H, Wicking C, Zaphiropoulous PG, et al. Mutations of the human homolog of Drosophila patched in the nevoid basal cell carcinoma syndrome. Cell 1996;85:841-51
-
(1996)
Cell
, vol.85
, pp. 841-851
-
-
Hahn, H.1
Wicking, C.2
Zaphiropoulous, P.G.3
-
7
-
-
15844381336
-
Human homolog of patched, a candidate gene for the basal cell nevus syndrome
-
Johnson RL, Rothman AL, Xie J, et al. Human homolog of patched, a candidate gene for the basal cell nevus syndrome. Science 1996;272:1668-71
-
(1996)
Science
, vol.272
, pp. 1668-1671
-
-
Johnson, R.L.1
Rothman, A.L.2
Xie, J.3
-
8
-
-
13444251046
-
Constitutive activation of the shh-ptc1 pathway by a patched1 mutation identified in BCC
-
Barnes EA, Heidtman KJ, Donoghue DJ. Constitutive activation of the shh-ptc1 pathway by a patched1 mutation identified in BCC. Oncogene 2005;24:902-15
-
(2005)
Oncogene
, vol.24
, pp. 902-915
-
-
Barnes, E.A.1
Heidtman, K.J.2
Donoghue, D.J.3
-
9
-
-
0035577854
-
Hedgehog signaling in animal development: Paradigms and principles
-
Ingham PW, McMahon AP. Hedgehog signaling in animal development: Paradigms and principles. Genes Dev 2001;15:3059-87
-
(2001)
Genes Dev
, vol.15
, pp. 3059-3087
-
-
Ingham, P.W.1
McMahon, A.P.2
-
10
-
-
0030297553
-
Dual roles for patched in sequestering and transducing Hedgehog
-
Chen Y, Struhl G. Dual roles for patched in sequestering and transducing Hedgehog. Cell 1996;87:553-63
-
(1996)
Cell
, vol.87
, pp. 553-563
-
-
Chen, Y.1
Struhl, G.2
-
11
-
-
0031913524
-
Activating Smoothened mutations in sporadic basal-cell carcinoma
-
Xie J, Murone M, Luoh SM, et al. Activating Smoothened mutations in sporadic basal-cell carcinoma. Nature 1998;391:90-2
-
(1998)
Nature
, vol.391
, pp. 90-92
-
-
Xie, J.1
Murone, M.2
Luoh, S.M.3
-
12
-
-
0035001278
-
Activation of expression of hedgehog target genes in basal cell carcinomas
-
Bonifas JM, Pennypacker S, Chuang PT, et al. Activation of expression of hedgehog target genes in basal cell carcinomas. J Invest Dermatol 2001;116:739-42
-
(2001)
J Invest Dermatol
, vol.116
, pp. 739-742
-
-
Bonifas, J.M.1
Pennypacker, S.2
Chuang, P.T.3
-
13
-
-
0037118056
-
Hedgehog regulates cell growth and proliferation by inducing cyclin D and cyclin e
-
Duman-Scheel M, Weng L, Xin S, et al. Hedgehog regulates cell growth and proliferation by inducing cyclin D and cyclin E. Nature 2002;417:299-304
-
(2002)
Nature
, vol.417
, pp. 299-304
-
-
Duman-Scheel, M.1
Weng, L.2
Xin, S.3
-
14
-
-
0034960583
-
The morphogen Sonic hedgehog is an indirect angiogenic agent upregulating two families of angiogenic growth factors
-
Pola R, Ling LE, Silver M, et al. The morphogen Sonic hedgehog is an indirect angiogenic agent upregulating two families of angiogenic growth factors. Nat Med 2001;7:706-11
-
(2001)
Nat Med
, vol.7
, pp. 706-711
-
-
Pola, R.1
Ling, L.E.2
Silver, M.3
-
16
-
-
79951904426
-
Clinical experience with hedgehog pathway inhibitors
-
Low JA, de Sauvage FJ. Clinical experience with hedgehog pathway inhibitors. J Clin Oncol 2010;28:5321-6
-
(2010)
J Clin Oncol
, vol.28
, pp. 5321-5326
-
-
Low, J.A.1
De Sauvage, F.J.2
-
17
-
-
72949103044
-
Small-molecule modulators of the Sonic Hedgehog signaling pathway
-
Stanton BZ, Peng LF. Small-molecule modulators of the Sonic Hedgehog signaling pathway. Mol Biosyst 2010;6:44-54
-
(2010)
Mol Biosyst
, vol.6
, pp. 44-54
-
-
Stanton, B.Z.1
Peng, L.F.2
-
18
-
-
79955990024
-
Targeting superficial or nodular Basal cell carcinoma with topically formulated small molecule inhibitor of smoothened
-
Tang T, Tang JY, Li D, et al. Targeting superficial or nodular Basal cell carcinoma with topically formulated small molecule inhibitor of smoothened. Clin Cancer Res 2011;17:3378-87
-
(2011)
Clin Cancer Res
, vol.17
, pp. 3378-3387
-
-
Tang, T.1
Tang, J.Y.2
Li, D.3
-
19
-
-
79954611501
-
Phase i trial of hedgehog pathway inhibitor vismodegib (GDC-0449) in patients with refractory, locally advanced or metastatic solid tumors
-
LoRusso PM, Rudin CM, Reddy JC, et al. Phase I trial of hedgehog pathway inhibitor vismodegib (GDC-0449) in patients with refractory, locally advanced or metastatic solid tumors. Clin Cancer Res 2011;17:2502-11
-
(2011)
Clin Cancer Res
, vol.17
, pp. 2502-2511
-
-
Lorusso, P.M.1
Rudin, C.M.2
Reddy, J.C.3
-
20
-
-
80052475002
-
Pharmacokinetic dose-scheduling study of hedgehog pathway inhibitor vismodegib (GDC-0449) in patients with locally advanced or metastatic solid tumors
-
Lorusso PM, Jimeno A, Dy G, et al. Pharmacokinetic dose-scheduling study of hedgehog pathway inhibitor vismodegib (GDC-0449) in patients with locally advanced or metastatic solid tumors. Clin Cancer Res 2011;17:5774-82
-
(2011)
Clin Cancer Res
, vol.17
, pp. 5774-5782
-
-
Lorusso, P.M.1
Jimeno, A.2
Dy, G.3
-
21
-
-
70349238733
-
Inhibition of the hedgehog pathway in advanced basal-cell carcinoma
-
Von Hoff DD, LoRusso PM, Rudin CM, et al. Inhibition of the hedgehog pathway in advanced basal-cell carcinoma. N Engl J Med 2009;361:1164-72
-
(2009)
N Engl J Med
, vol.361
, pp. 1164-1172
-
-
Von Hoff, D.D.1
Lorusso, P.M.2
Rudin, C.M.3
-
22
-
-
84861856844
-
Efficacy and safety of vismodegib in advanced basal-cell carcinoma
-
Sekulic A, Migden MR, Oro AE, et al. Efficacy and safety of vismodegib in advanced basal-cell carcinoma. N Engl J Med 2012;366:2171-9
-
(2012)
N Engl J Med
, vol.366
, pp. 2171-2179
-
-
Sekulic, A.1
Migden, M.R.2
Oro, A.E.3
-
23
-
-
0031002840
-
Clinical manifestations in 105 persons with nevoid basal cell carcinoma syndrome
-
Kimonis VE, Goldstein AM, Pastakia B, et al. Clinical manifestations in 105 persons with nevoid basal cell carcinoma syndrome. Am J Med Genet 1997;69:299-308
-
(1997)
Am J Med Genet
, vol.69
, pp. 299-308
-
-
Kimonis, V.E.1
Goldstein, A.M.2
Pastakia, B.3
-
24
-
-
84861876867
-
Inhibiting the hedgehog pathway in patients with the basal-cell nevus syndrome
-
Tang JY, Mackay-Wiggan JM, Aszterbaum M, et al. Inhibiting the hedgehog pathway in patients with the basal-cell nevus syndrome. N Engl J Med 2012;366:2180-8
-
(2012)
N Engl J Med
, vol.366
, pp. 2180-2188
-
-
Tang, J.Y.1
Mackay-Wiggan, J.M.2
Aszterbaum, M.3
-
26
-
-
74049134387
-
Epidermal growth factor receptor (EGFR) expression in periocular and extraocular sebaceous carcinoma
-
Ivan D, Prieto VG, Esmaeli B, et al. Epidermal growth factor receptor (EGFR) expression in periocular and extraocular sebaceous carcinoma. J Cutan Pathol 2010;37:231-6
-
(2010)
J Cutan Pathol
, vol.37
, pp. 231-236
-
-
Ivan, D.1
Prieto, V.G.2
Esmaeli, B.3
-
27
-
-
79958748174
-
Epidermal growth factor receptor (EGFR) and squamous cell carcinoma of the skin: Molecular bases for EGFRtargeted therapy
-
Uribe P, Gonzalez S. Epidermal growth factor receptor (EGFR) and squamous cell carcinoma of the skin: Molecular bases for EGFRtargeted therapy. Pathol Res Pract 2011;207:337-42
-
(2011)
Pathol Res Pract
, vol.207
, pp. 337-342
-
-
Uribe, P.1
Gonzalez, S.2
-
28
-
-
17444410011
-
Immunohistochemical analysis of EGFR and HER-2 in patients with metastatic squamous cell carcinoma of the skin
-
Maubec E, Duvillard P, Velasco V, et al. Immunohistochemical analysis of EGFR and HER-2 in patients with metastatic squamous cell carcinoma of the skin. Anticancer Res 2005;25(2B):1205-10
-
(2005)
Anticancer Res
, vol.25
, Issue.2
, pp. 1205-1210
-
-
Maubec, E.1
Duvillard, P.2
Velasco, V.3
-
29
-
-
38849091450
-
Epidermal growth factor receptor: A novel biomarker for aggressive head and neck cutaneous squamous cell carcinoma
-
Ch'ng S, Low I, Ng D, et al. Epidermal growth factor receptor: A novel biomarker for aggressive head and neck cutaneous squamous cell carcinoma. Hum Pathol 2008;39:344-9
-
(2008)
Hum Pathol
, vol.39
, pp. 344-349
-
-
Ch'Ng, S.1
Low, I.2
Ng, D.3
-
30
-
-
0034980383
-
Epidermal growth factor receptor overexpression and genetic aberrations in metastatic squamous-cell carcinoma of the skin
-
Shimizu T, Izumi H, Oga A, et al. Epidermal growth factor receptor overexpression and genetic aberrations in metastatic squamous-cell carcinoma of the skin. Dermatology (Basel) 2001;202:203-6
-
(2001)
Dermatology (Basel
, vol.202
, pp. 203-206
-
-
Shimizu, T.1
Izumi, H.2
Oga, A.3
-
31
-
-
33646675355
-
Expression of the epidermal growth factor receptor in conjunctival squamous cell carcinoma
-
Shepler TR, Prieto VG, Diba R, et al. Expression of the epidermal growth factor receptor in conjunctival squamous cell carcinoma. Ophthal Plast Reconstr Surg 2006;22:113-5
-
(2006)
Ophthal Plast Reconstr Surg
, vol.22
, pp. 113-115
-
-
Shepler, T.R.1
Prieto, V.G.2
Diba, R.3
-
32
-
-
0027818836
-
Blockade of epidermal growth factor receptor function by bivalent and monovalent fragments of 225 anti-epidermal growth factor receptor monoclonal antibodies
-
Fan Z, Masui H, Altas I, et al. Blockade of epidermal growth factor receptor function by bivalent and monovalent fragments of 225 anti-epidermal growth factor receptor monoclonal antibodies. Cancer Res 1993;53:4322-8
-
(1993)
Cancer Res
, vol.53
, pp. 4322-4328
-
-
Fan, Z.1
Masui, H.2
Altas, I.3
-
33
-
-
80052748563
-
Phase II study of cetuximab as first-line single-drug therapy in patients with unresectable squamous cell carcinoma of the skin
-
Maubec E, Petrow P, Scheer-Senyarich I, et al. Phase II study of cetuximab as first-line single-drug therapy in patients with unresectable squamous cell carcinoma of the skin. J Clin Oncol 2011;29:3419-26
-
(2011)
J Clin Oncol
, vol.29
, pp. 3419-3426
-
-
Maubec, E.1
Petrow, P.2
Scheer-Senyarich, I.3
-
34
-
-
0037109014
-
ZD1839 (Iressa): An orally active inhibitor of epidermal growth factor signaling with potential for cancer therapy
-
Wakeling AE, Guy SP, Woodburn JR, et al. ZD1839 (Iressa): An orally active inhibitor of epidermal growth factor signaling with potential for cancer therapy. Cancer Res 2002;62:5749-54
-
(2002)
Cancer Res
, vol.62
, pp. 5749-5754
-
-
Wakeling, A.E.1
Guy, S.P.2
Woodburn, J.R.3
-
35
-
-
84857700579
-
A phase II study of gefitinib for aggressive cutaneous squamous cell carcinoma of the head and neck
-
Lewis CM, Glisson BS, Feng L, et al. A phase II study of gefitinib for aggressive cutaneous squamous cell carcinoma of the head and neck. Clin Cancer Res 2012;18:1435-46
-
(2012)
Clin Cancer Res
, vol.18
, pp. 1435-1446
-
-
Lewis, C.M.1
Glisson, B.S.2
Feng, L.3
-
36
-
-
0030774045
-
Induction of apoptosis and cell cycle arrest by CP-358 ,774, an inhibitor of epidermal growth factor receptor tyrosine kinase
-
Moyer JD, Barbacci EG, Iwata KK, et al. Induction of apoptosis and cell cycle arrest by CP-358,774, an inhibitor of epidermal growth factor receptor tyrosine kinase. Cancer Res 1997;57: 4838-48
-
(1997)
Cancer Res
, vol.57
, pp. 4838-4848
-
-
Moyer, J.D.1
Barbacci, E.G.2
Iwata, K.K.3
-
37
-
-
77958179944
-
Erlotinib in advanced non-small cell lung cancer: Efficacy and safety findings of the global phase IV Tarceva Lung Cancer Survival Treatment study
-
Reck M, van Zandwijk N, Gridelli C, et al. Erlotinib in advanced non-small cell lung cancer: Efficacy and safety findings of the global phase IV Tarceva Lung Cancer Survival Treatment study. J Thorac Oncol 2010;5:1616-22
-
(2010)
J Thorac Oncol
, vol.5
, pp. 1616-1622
-
-
Reck, M.1
Van Zandwijk, N.2
Gridelli, C.3
-
38
-
-
0035398631
-
Phase i and pharmacologic study of OSI-774, an epidermal growth factor receptor tyrosine kinase inhibitor, in patients with advanced solid malignancies
-
Hidalgo M, Siu LL, Nemunaitis J, et al. Phase I and pharmacologic study of OSI-774, an epidermal growth factor receptor tyrosine kinase inhibitor, in patients with advanced solid malignancies. J Clin Oncol 2001;19:3267-79
-
(2001)
J Clin Oncol
, vol.19
, pp. 3267-3279
-
-
Hidalgo, M.1
Siu, L.L.2
Nemunaitis, J.3
-
40
-
-
58149295790
-
A case of trichomegaly of the eyelashes and facial hypertrichosis induced by erlotinib (Tarceva
-
Márquez G, Herrera-Acosta E, Vidal I, et al. A case of trichomegaly of the eyelashes and facial hypertrichosis induced by erlotinib (Tarceva). Int J Dermatol 2009;48:97-8
-
(2009)
Int J Dermatol
, vol.48
, pp. 97-98
-
-
Márquez, G.1
Herrera-Acosta, E.2
Vidal, I.3
-
42
-
-
79958841762
-
Metastatic cutaneous squamous cell carcinoma responding to erlotinib therapy
-
Engelhardt C, Curiel-Lewandrowski C, Warneke J, et al. Metastatic cutaneous squamous cell carcinoma responding to erlotinib therapy. J Am Acad Dermatol 2011;65:237-8
-
(2011)
J Am Acad Dermatol
, vol.65
, pp. 237-238
-
-
Engelhardt, C.1
Curiel-Lewandrowski, C.2
Warneke, J.3
-
43
-
-
78650976554
-
Squamous carcinoma of the skin responding to erlotinib: Three cases
-
Read WL. Squamous carcinoma of the skin responding to erlotinib: Three cases. J Clin Oncol 2007;25:1651-9
-
(2007)
J Clin Oncol
, vol.25
, pp. 1651-1659
-
-
Read, W.L.1
-
44
-
-
84871230240
-
Epidermal growth factor receptor inhibitors for treatment of orbital squamous cell carcinoma
-
El-Sawy T, Sabichi AL, Myers JN, et al. Epidermal growth factor receptor inhibitors for treatment of orbital squamous cell carcinoma. Arch Ophthalmol 2012;130:1608-11
-
(2012)
Arch Ophthalmol
, vol.130
, pp. 1608-1611
-
-
El-Sawy, T.1
Sabichi, A.L.2
Myers, J.N.3
|