-
1
-
-
67650299973
-
The development of gene therapy: From monogenic recessive disorders to complex diseases such as cancer
-
Gillet, J.P.; Macadangdang, B.; Fathke, R.L.; Gottesman, M.M.; Kimchi-Sarfaty, C. The development of gene therapy: From monogenic recessive disorders to complex diseases such as cancer. Methods Mol. Biol. 2009, 542, 5–54.
-
(2009)
Methods Mol.Biol
, vol.542
, pp. 5-54
-
-
Gillet, J.P.1
Macadangdang, B.2
Fathke, R.L.3
Gottesman, M.M.4
Kimchi-Sarfaty, C.5
-
2
-
-
0026937479
-
A brief history of gene therapy
-
Friedmann, T. A brief history of gene therapy. Nat. Genet. 1992, 2, 93–98.
-
(1992)
Nat. Genet
, vol.2
, pp. 93-98
-
-
Friedmann, T.1
-
3
-
-
0024988334
-
Gene transfer into humans—Immunotherapy of patients with advanced melanoma, using tumor-infiltrating lymphocytes modified by retroviral gene transduction
-
Rosenberg, S.A.; Aebersold, P.; Cornetta, K.; Kasid, A.; Morgan, R.A.; Moen, R.; Karson, E.M.; Lotze, M.T.; Yang, J.C.; Topalian, S.L.; et al. Gene transfer into humans—Immunotherapy of patients with advanced melanoma, using tumor-infiltrating lymphocytes modified by retroviral gene transduction. N. Engl. J. Med. 1990, 323, 570–578.
-
(1990)
N. Engl. J. Med
, vol.323
, pp. 570-578
-
-
Rosenberg, S.A.1
Aebersold, P.2
Cornetta, K.3
Kasid, A.4
Morgan, R.A.5
Moen, R.6
Karson, E.M.7
Lotze, M.T.8
Yang, J.C.9
Topalian, S.L.10
-
4
-
-
35148817461
-
Gene therapy clinical trials worldwide to 2007—An update
-
Edelstein, M.L.; Abedi, M.R.; Wixon, J. Gene therapy clinical trials worldwide to 2007—An update. J. Gene Med. 2007, 9, 833–842.
-
(2007)
J. Gene Med
, vol.9
, pp. 833-842
-
-
Edelstein, M.L.1
Abedi, M.R.2
Wixon, J.3
-
5
-
-
77956156776
-
Targeted systemic gene therapy and molecular imaging of cancer contribution of the vascular-targeted aavp vector
-
Hajitou, A. Targeted systemic gene therapy and molecular imaging of cancer contribution of the vascular-targeted aavp vector. Adv. Genet. 2010, 69, 65–82.
-
(2010)
Adv. Genet
, vol.69
, pp. 65-82
-
-
Hajitou, A.1
-
6
-
-
22944478652
-
Transcriptionally targeted adenovirus vectors
-
Sadeghi, H.; Hitt, M.M. Transcriptionally targeted adenovirus vectors. Curr. Gene Ther. 2005, 5, 411–427.
-
(2005)
Curr. Gene Ther
, vol.5
, pp. 411-427
-
-
Sadeghi, H.1
Hitt, M.M.2
-
7
-
-
0027155874
-
In vivo promoter activity and transgene expression in mammalian somatic tissues evaluated by using particle bombardment
-
Cheng, L.; Ziegelhoffer, P.R.; Yang, N.S. In vivo promoter activity and transgene expression in mammalian somatic tissues evaluated by using particle bombardment. Proc. Natl. Acad. Sci. USA 1993, 90, 4455–4459.
-
(1993)
Proc. Natl. Acad. Sci. USA
, vol.90
, pp. 4455-4459
-
-
Cheng, L.1
Ziegelhoffer, P.R.2
Yang, N.S.3
-
8
-
-
0030790684
-
Prostate attenuated replication competent adenovirus (Arca) cn706: A selective cytotoxic for prostate-specific antigen-positive prostate cancer cells
-
Rodriguez, R.; Schuur, E.R.; Lim, H.Y.; Henderson, G.A.; Simons, J.W.; Henderson, D.R. Prostate attenuated replication competent adenovirus (arca) cn706: A selective cytotoxic for prostate-specific antigen-positive prostate cancer cells. Cancer Res. 1997, 57, 2559–2563.
-
(1997)
Cancer Res
, vol.57
, pp. 2559-2563
-
-
Rodriguez, R.1
Schuur, E.R.2
Lim, H.Y.3
Henderson, G.A.4
Simons, J.W.5
Henderson, D.R.6
-
9
-
-
0030957912
-
Transcriptional targeting of herpes simplex virus for cell-specific replication
-
Miyatake, S.; Iyer, A.; Martuza, R.L.; Rabkin, S.D. Transcriptional targeting of herpes simplex virus for cell-specific replication. J. Virol. 1997, 71, 5124–5132.
-
(1997)
J. Virol
, vol.71
, pp. 5124-5132
-
-
Miyatake, S.1
Iyer, A.2
Martuza, R.L.3
Rabkin, S.D.4
-
10
-
-
0038347805
-
Transcriptional targeting in cancer gene therapy
-
Robson, T.; Hirst, D.G. Transcriptional targeting in cancer gene therapy. J. Biomed. Biotechnol. 2003, 2003, 110–137.
-
(2003)
J. Biomed. Biotechnol
, vol.2003
, pp. 110-137
-
-
Robson, T.1
Hirst, D.G.2
-
11
-
-
0036169256
-
Targeted gene therapy of ovarian cancer using an ovarian-specific promoter
-
Bao, R.; Selvakumaran, M.; Hamilton, T.C. Targeted gene therapy of ovarian cancer using an ovarian-specific promoter. Gynecol. Oncol. 2002, 84, 228–234.
-
(2002)
Gynecol. Oncol
, vol.84
, pp. 228-234
-
-
Bao, R.1
Selvakumaran, M.2
Hamilton, T.C.3
-
12
-
-
0031459465
-
Tissue-specific expression of herpes simplex virus thymidine kinase gene delivered by adeno-associated virus inhibits the growth of human hepatocellular carcinoma in athymic mice
-
Su, H.; Lu, R.; Chang, J.C.; Kan, Y.W. Tissue-specific expression of herpes simplex virus thymidine kinase gene delivered by adeno-associated virus inhibits the growth of human hepatocellular carcinoma in athymic mice. Proc. Natl. Acad. Sci. USA 1997, 94, 13891–13896.
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, pp. 13891-13896
-
-
Su, H.1
Lu, R.2
Chang, J.C.3
Kan, Y.W.4
-
13
-
-
0035100611
-
Adenoviral-mediated gene therapy for thyroid carcinoma using thymidine kinase controlled by thyroglobulin promoter demonstrates high specificity and low toxicity
-
Zhang, R.; Straus, F.H.; DeGroot, L.J. Adenoviral-mediated gene therapy for thyroid carcinoma using thymidine kinase controlled by thyroglobulin promoter demonstrates high specificity and low toxicity. Thyroid 2001, 11, 115–123.
-
(2001)
Thyroid
, vol.11
, pp. 115-123
-
-
Zhang, R.1
Straus, F.H.2
Degroot, L.J.3
-
14
-
-
79954566850
-
Efficient melanoma cell killing and reduced melanoma growth in mice by a selective replicating adenovirus armed with tumor necrosis factor-related apoptosis-inducing ligand
-
Fecker, L.F.; Ruckert, S.; Kurbanov, B.M.; Schmude, M.; Stockfleth, E.; Fechner, H.; Eberle, J. Efficient melanoma cell killing and reduced melanoma growth in mice by a selective replicating adenovirus armed with tumor necrosis factor-related apoptosis-inducing ligand. Hum. Gene Ther. 2011, 22, 405–417.
-
(2011)
Hum. Gene Ther
, vol.22
, pp. 405-417
-
-
Fecker, L.F.1
Ruckert, S.2
Kurbanov, B.M.3
Schmude, M.4
Stockfleth, E.5
Fechner, H.6
Eberle, J.7
-
15
-
-
84855482503
-
Novel, chimeric, cancer-specific, and radiation-inducible gene promoters for suicide gene therapy of cancer
-
Xiong, J.; Sun, W.J.; Wang, W.F.; Liao, Z.K.; Zhou, F.X.; Kong, H.Y.; Xu, Y.; Xie, C.H.; Zhou, Y.F. Novel, chimeric, cancer-specific, and radiation-inducible gene promoters for suicide gene therapy of cancer. Cancer 2012, 118, 536–548.
-
(2012)
Cancer
, vol.118
, pp. 536-548
-
-
Xiong, J.1
Sun, W.J.2
Wang, W.F.3
Liao, Z.K.4
Zhou, F.X.5
Kong, H.Y.6
Xu, Y.7
Xie, C.H.8
Zhou, Y.F.9
-
16
-
-
0036494498
-
The flt-1 promoter for transcriptional targeting of teratocarcinoma
-
Bauerschmitz, G.J.; Nettelbeck, D.M.; Kanerva, A.; Baker, A.H.; Hemminki, A.; Reynolds, P.N.; Curiel, D.T. The flt-1 promoter for transcriptional targeting of teratocarcinoma. Cancer Res. 2002, 62, 1271–1274.
-
(2002)
Cancer Res
, vol.62
, pp. 1271-1274
-
-
Bauerschmitz, G.J.1
Nettelbeck, D.M.2
Kanerva, A.3
Baker, A.H.4
Hemminki, A.5
Reynolds, P.N.6
Curiel, D.T.7
-
17
-
-
84863005720
-
Eukaryotic expression vectors bearing genes encoding cytotoxic proteins for cancer gene therapy
-
Glinka, E.M. Eukaryotic expression vectors bearing genes encoding cytotoxic proteins for cancer gene therapy. Plasmid 2012, 68, 69–85.
-
(2012)
Plasmid
, vol.68
, pp. 69-85
-
-
Glinka, E.M.1
-
18
-
-
0034985866
-
A simplified system for constructing recombinant adenoviral vectors containing heterologous peptides in the hi loop of their fiber knob
-
Mizuguchi, H.; Koizumi, N.; Hosono, T.; Utoguchi, N.; Watanabe, Y.; Kay, M.A.; Hayakawa, T. A simplified system for constructing recombinant adenoviral vectors containing heterologous peptides in the hi loop of their fiber knob. Gene Ther. 2001, 8, 730–735.
-
(2001)
Gene Ther
, vol.8
, pp. 730-735
-
-
Mizuguchi, H.1
Koizumi, N.2
Hosono, T.3
Utoguchi, N.4
Watanabe, Y.5
Kay, M.A.6
Hayakawa, T.7
-
19
-
-
83555178348
-
Enhancing the therapeutic efficacy of adenovirus in combination with biomaterials
-
Kim, J.; Kim, P.H.; Kim, S.W.; Yun, C.O. Enhancing the therapeutic efficacy of adenovirus in combination with biomaterials. Biomaterials 2012, 33, 1838–1850.
-
(2012)
Biomaterials
, vol.33
, pp. 1838-1850
-
-
Kim, J.1
Kim, P.H.2
Kim, S.W.3
Yun, C.O.4
-
20
-
-
46449091470
-
Transcriptional targeting of gene expression in breast cancer by the promoters of protein regulator of cytokinesis 1 and ribonuclease reductase 2
-
Yun, H.J.; Cho, Y.H.; Moon, Y.; Park, Y.W.; Yoon, H.K.; Kim, Y.J.; Cho, S.H.; Lee, Y.I.; Kang, B.S.; Kim, W.J.; et al. Transcriptional targeting of gene expression in breast cancer by the promoters of protein regulator of cytokinesis 1 and ribonuclease reductase 2. Exp. Mol. Med. 2008, 40, 345–353.
-
(2008)
Exp. Mol. Med
, vol.40
, pp. 345-353
-
-
Yun, H.J.1
Cho, Y.H.2
Moon, Y.3
Park, Y.W.4
Yoon, H.K.5
Kim, Y.J.6
Cho, S.H.7
Lee, Y.I.8
Kang, B.S.9
Kim, W.J.10
-
21
-
-
0034963928
-
Incorporation of tumor-targeting peptides into recombinantadeno-associated virus capsids
-
Grifman, M.; Trepel, M.; Speece, P.; Gilbert, L.B.; Arap, W.; Pasqualini, R.; Weitzman, M.D. Incorporation of tumor-targeting peptides into recombinant adeno-associated virus capsids. Mol. Ther. 2001, 3, 964–975.
-
(2001)
Mol. Ther
, vol.3
, pp. 964-975
-
-
Grifman, M.1
Trepel, M.2
Speece, P.3
Gilbert, L.B.4
Arap, W.5
Pasqualini, R.6
Weitzman, M.D.7
-
22
-
-
78649984931
-
Novel tumour-specific promoters for transcriptional targeting of hepatocellular carcinoma by herpes simplex virus vectors
-
Foka, P.; Pourchet, A.; Hernandez-Alcoceba, R.; Doumba, P.P.; Pissas, G.; Kouvatsis, V.; Dalagiorgou, G.; Kazazi, D.; Marconi, P.; Foschini, M.; et al. Novel tumour-specific promoters for transcriptional targeting of hepatocellular carcinoma by herpes simplex virus vectors. J. Gene Med. 2010, 12, 956–967.
-
(2010)
J. Gene Med
, vol.12
, pp. 956-967
-
-
Foka, P.1
Pourchet, A.2
Hernandez-Alcoceba, R.3
Doumba, P.P.4
Pissas, G.5
Kouvatsis, V.6
Dalagiorgou, G.7
Kazazi, D.8
Marconi, P.9
Foschini, M.10
-
23
-
-
69249084080
-
Targeted gene delivery to cd117-expressing cells in vivo with lentiviral vectors co-displaying stem cell factor and a fusogenic molecule
-
Froelich, S.; Ziegler, L.; Stroup, K.; Wang, P. Targeted gene delivery to cd117-expressing cells in vivo with lentiviral vectors co-displaying stem cell factor and a fusogenic molecule. Biotechnol. Bioeng. 2009, 104, 206–215.
-
(2009)
Biotechnol. Bioeng
, vol.104
, pp. 206-215
-
-
Froelich, S.1
Ziegler, L.2
Stroup, K.3
Wang, P.4
-
24
-
-
0031564328
-
Endothelial cell-specific expression of tumor necrosis factor-alpha from the kdr or e-selectin promoters following retroviral delivery
-
Jaggar, R.T.; Chan, H.Y.; Harris, A.L.; Bicknell, R. Endothelial cell-specific expression of tumor necrosis factor-alpha from the kdr or e-selectin promoters following retroviral delivery. Hum. Gene Ther. 1997, 8, 2239–2247.
-
(1997)
Hum. Gene Ther
, vol.8
, pp. 2239-2247
-
-
Jaggar, R.T.1
Chan, H.Y.2
Harris, A.L.3
Bicknell, R.4
-
25
-
-
0027958873
-
The glucose-regulated proteins (Grp78 and grp94): Functions, gene regulation, and applications
-
Little, E.; Ramakrishnan, M.; Roy, B.; Gazit, G.; Lee, A.S. The glucose-regulated proteins (grp78 and grp94): Functions, gene regulation, and applications. Crit. Rev. Eukaryot. Gene Expr. 1994, 4, 1–18.
-
(1994)
Crit. Rev. Eukaryot. Gene Expr
, vol.4
, pp. 1-18
-
-
Little, E.1
Ramakrishnan, M.2
Roy, B.3
Gazit, G.4
Lee, A.S.5
-
26
-
-
33846213523
-
Retargeted oncolytic measles strains entering via the egfrviii receptor maintain significant antitumor activity against gliomas with increased tumor specificity
-
Allen, C.; Vongpunsawad, S.; Nakamura, T.; James, C.D.; Schroeder, M.; Cattaneo, R.; Giannini, C.; Krempski, J.; Peng, K.W.; Goble, J.M.; et al. Retargeted oncolytic measles strains entering via the egfrviii receptor maintain significant antitumor activity against gliomas with increased tumor specificity. Cancer Res. 2006, 66, 11840–11850.
-
(2006)
Cancer Res
, vol.66
, pp. 11840-11850
-
-
Allen, C.1
Vongpunsawad, S.2
Nakamura, T.3
James, C.D.4
Schroeder, M.5
Cattaneo, R.6
Giannini, C.7
Krempski, J.8
Peng, K.W.9
Goble, J.M.10
-
27
-
-
0032323792
-
Development of prostate-specific antigen promoter-based gene therapy for androgen-independent human prostate cancer
-
Gotoh, A.; Ko, S.C.; Shirakawa, T.; Cheon, J.; Kao, C.; Miyamoto, T.; Gardner, T.A.; Ho, L.J.; Cleutjens, C.B.; Trapman, J.; et al. Development of prostate-specific antigen promoter-based gene therapy for androgen-independent human prostate cancer. J. Urol. 1998, 160, 220–229.
-
(1998)
J. Urol
, vol.160
, pp. 220-229
-
-
Gotoh, A.1
Ko, S.C.2
Shirakawa, T.3
Cheon, J.4
Kao, C.5
Miyamoto, T.6
Gardner, T.A.7
Ho, L.J.8
Cleutjens, C.B.9
Trapman, J.10
-
28
-
-
0029066169
-
Telomerase activity in normal and malignant hematopoietic cells
-
Broccoli, D.; Young, J.W.; de Lange, T. Telomerase activity in normal and malignant hematopoietic cells. Proc. Natl. Acad. Sci. USA 1995, 92, 9082–9086.
-
(1995)
Proc. Natl. Acad. Sci. USA
, vol.92
, pp. 9082-9086
-
-
Broccoli, D.1
Young, J.W.2
De Lange, T.3
-
29
-
-
0032959142
-
Utilization of variant-type of human alpha-fetoprotein promoter in gene therapy targeting for hepatocellular carcinoma
-
Ishikawa, H.; Nakata, K.; Mawatari, F.; Ueki, T.; Tsuruta, S.; Ido, A.; Nakao, K.; Kato, Y.; Ishii, N.; Eguchi, K.; et al. Utilization of variant-type of human alpha-fetoprotein promoter in gene therapy targeting for hepatocellular carcinoma. Gene Ther. 1999, 6, 465–470.
-
(1999)
Gene Ther
, vol.6
, pp. 465-470
-
-
Ishikawa, H.1
Nakata, K.2
Mawatari, F.3
Ueki, T.4
Tsuruta, S.5
Ido, A.6
Nakao, K.7
Kato, Y.8
Ishii, N.9
Eguchi, K.10
-
30
-
-
58849088990
-
Tissue specific cytotoxicity of colon cancer cells mediated by nanoparticle-delivered suicide gene in vitro and in vivo
-
Zhang, G.; Liu, T.; Chen, Y.H.; Chen, Y.; Xu, M.; Peng, J.; Yu, S.; Yuan, J.; Zhang, X. Tissue specific cytotoxicity of colon cancer cells mediated by nanoparticle-delivered suicide gene in vitro and in vivo. Clin. Cancer Res. 2009, 15, 201–207.
-
(2009)
Clin. Cancer Res
, vol.15
, pp. 201-207
-
-
Zhang, G.1
Liu, T.2
Chen, Y.H.3
Chen, Y.4
Xu, M.5
Peng, J.6
Yu, S.7
Yuan, J.8
Zhang, X.9
-
31
-
-
84857498950
-
Live monitoring of small vessels during development and disease using the flt-1 promoter element
-
Herz, K.; Heinemann, J.C.; Hesse, M.; Ottersbach, A.; Geisen, C.; Fuegemann, C.J.; Roll, W.; Fleischmann, B.K.; Wenzel, D. Live monitoring of small vessels during development and disease using the flt-1 promoter element. Basic Res. Cardiol. 2012, 107, 1–14.
-
(2012)
Basic Res. Cardiol
, vol.107
, pp. 1-14
-
-
Herz, K.1
Heinemann, J.C.2
Hesse, M.3
Ottersbach, A.4
Geisen, C.5
Fuegemann, C.J.6
Roll, W.7
Fleischmann, B.K.8
Wenzel, D.9
-
32
-
-
4544325038
-
Spontaneous and controllable activation of suicide gene expression driven by the stress-inducible grp78 promoter resulting in eradication of sizable human tumors
-
Dong, D.; Dubeau, L.; Bading, J.; Nguyen, K.; Luna, M.; Yu, H.; Gazit-Bornstein, G.; Gordon, E.M.; Gomer, C.; Hall, F.L.; et al. Spontaneous and controllable activation of suicide gene expression driven by the stress-inducible grp78 promoter resulting in eradication of sizable human tumors. Hum. Gene Ther. 2004, 15, 553–561.
-
(2004)
Hum. Gene Ther
, vol.15
, pp. 553-561
-
-
Dong, D.1
Dubeau, L.2
Bading, J.3
Nguyen, K.4
Luna, M.5
Yu, H.6
Gazit-Bornstein, G.7
Gordon, E.M.8
Gomer, C.9
Hall, F.L.10
-
33
-
-
77955474897
-
Roles of grp78 in physiology and cancer
-
Zhang, L.H.; Zhang, X. Roles of grp78 in physiology and cancer. J. Cell. Biochem. 2010, 110, 1299–1305.
-
(2010)
J. Cell. Biochem
, vol.110
, pp. 1299-1305
-
-
Zhang, L.H.1
Zhang, X.2
-
34
-
-
79952842932
-
The critical role of grp78 in physiologic and pathologic stress
-
Pfaffenbach, K.T.; Lee, A.S. The critical role of grp78 in physiologic and pathologic stress. Curr. Opin. Cell Biol. 2011, 23, 150–156.
-
(2011)
Curr. Opin. Cell Biol
, vol.23
, pp. 150-156
-
-
Pfaffenbach, K.T.1
Lee, A.S.2
-
35
-
-
34248571826
-
Grp78 induction in cancer: Therapeutic and prognostic implications
-
Lee, A.S. Grp78 induction in cancer: Therapeutic and prognostic implications. Cancer Res. 2007, 67, 3496–3499.
-
(2007)
Cancer Res
, vol.67
, pp. 3496-3499
-
-
Lee, A.S.1
-
36
-
-
79954569520
-
A critical role for grp78/bip in the tumor microenvironment for neovascularization during tumor growth and metastasis
-
Dong, D.; Stapleton, C.; Luo, B.; Xiong, S.; Ye, W.; Zhang, Y.; Jhaveri, N.; Zhu, G.; Ye, R.; Liu, Z.; et al. A critical role for grp78/bip in the tumor microenvironment for neovascularization during tumor growth and metastasis. Cancer Res. 2011, 71, 2848–2857.
-
(2011)
Cancer Res
, vol.71
, pp. 2848-2857
-
-
Dong, D.1
Stapleton, C.2
Luo, B.3
Xiong, S.4
Ye, W.5
Zhang, Y.6
Jhaveri, N.7
Zhu, G.8
Ye, R.9
Liu, Z.10
-
37
-
-
77953387854
-
Endoplasmic reticulum stress response in cancer: Molecular mechanism and therapeutic potential
-
Wang, G.; Yang, Z.Q.; Zhang, K. Endoplasmic reticulum stress response in cancer: Molecular mechanism and therapeutic potential. Am. J. Transl. Res. 2010, 2, 65–74.
-
(2010)
Am. J. Transl. Res
, vol.2
, pp. 65-74
-
-
Wang, G.1
Yang, Z.Q.2
Zhang, K.3
-
38
-
-
35448967382
-
The unfolded protein response regulator grp78/bip as a novel target for increasing chemosensitivity in malignant gliomas
-
Pyrko, P.; Schonthal, A.H.; Hofman, F.M.; Chen, T.C.; Lee, A.S. The unfolded protein response regulator grp78/bip as a novel target for increasing chemosensitivity in malignant gliomas. Cancer Res. 2007, 67, 9809–9816.
-
(2007)
Cancer Res
, vol.67
, pp. 9809-9816
-
-
Pyrko, P.1
Schonthal, A.H.2
Hofman, F.M.3
Chen, T.C.4
Lee, A.S.5
-
39
-
-
67349101729
-
Effectiveness of hsv-tk suicide gene therapy driven by the grp78 stress-inducible promoter in esophagogastric junction and gastric adenocarcinomas
-
Azatian, A.; Yu, H.; Dai, W.; Schneiders, F.I.; Botelho, N.K.; Lord, R.V. Effectiveness of hsv-tk suicide gene therapy driven by the grp78 stress-inducible promoter in esophagogastric junction and gastric adenocarcinomas. J. Gastrointest. Surg. 2009, 13, 1044–1051.
-
(2009)
J. Gastrointest. Surg
, vol.13
, pp. 1044-1051
-
-
Azatian, A.1
Yu, H.2
Dai, W.3
Schneiders, F.I.4
Botelho, N.K.5
Lord, R.V.6
-
40
-
-
84871389700
-
Dual systemic tumor targeting with ligand-directed phage and grp78 promoter induces tumor regression
-
Kia, A.; Przystal, J.M.; Nianiaris, N.; Mazarakis, N.D.; Mintz, P.J.; Hajitou, A. Dual systemic tumor targeting with ligand-directed phage and grp78 promoter induces tumor regression. Mol. Cancer Ther. 2012, 11, 2566–2577.
-
(2012)
Mol.Cancer Ther
, vol.11
, pp. 2566-2577
-
-
Kia, A.1
Przystal, J.M.2
Nianiaris, N.3
Mazarakis, N.D.4
Mintz, P.J.5
Hajitou, A.6
-
41
-
-
0029932458
-
Organ targeting in vivo using phage display peptide libraries
-
Pasqualini, R.; Ruoslahti, E. Organ targeting in vivo using phage display peptide libraries. Nature 1996, 380, 364–366.
-
(1996)
Nature
, vol.380
, pp. 364-366
-
-
Pasqualini, R.1
Ruoslahti, E.2
-
42
-
-
33644994202
-
Vascular targeting: Recent advances and therapeutic perspectives
-
Hajitou, A.; Pasqualini, R.; Arap, W. Vascular targeting: Recent advances and therapeutic perspectives. Trends Cardiovasc. Med. 2006, 16, 80–88.
-
(2006)
Trends Cardiovasc. Med
, vol.16
, pp. 80-88
-
-
Hajitou, A.1
Pasqualini, R.2
Arap, W.3
-
43
-
-
0031006415
-
Addressing tumor blood vessels
-
Folkman, J. Addressing tumor blood vessels. Nat. Biotechnol. 1997, 15, 510, doi:10.1038/nbt0697-510.
-
(1997)
Nat. Biotechnol
, vol.15
, pp. 510
-
-
Folkman, J.1
-
44
-
-
33748290173
-
Gene therapy progress and prospects: Non-viral gene therapy by systemic delivery
-
Li, S.D.; Huang, L. Gene therapy progress and prospects: Non-viral gene therapy by systemic delivery. Gene Ther. 2006, 13, 1313–1319.
-
(2006)
Gene Ther
, vol.13
, pp. 1313-1319
-
-
Li, S.D.1
Huang, L.2
-
45
-
-
34447535345
-
Engineering targeted viral vectors for gene therapy
-
Waehler, R.; Russell, S.J.; Curiel, D.T. Engineering targeted viral vectors for gene therapy. Nat. Rev. Genet. 2007, 8, 573–587.
-
(2007)
Nat. Rev. Genet
, vol.8
, pp. 573-587
-
-
Waehler, R.1
Russell, S.J.2
Curiel, D.T.3
-
46
-
-
68549087056
-
Viral vectors: From virology to transgene expression
-
Bouard, D.; Alazard-Dany, D.; Cosset, F.L. Viral vectors: From virology to transgene expression. Br. J. Pharmacol. 2009, 157, 153–165.
-
(2009)
Br. J. Pharmacol
, vol.157
, pp. 153-165
-
-
Bouard, D.1
Alazard-Dany, D.2
Cosset, F.L.3
-
47
-
-
79954650563
-
State-of-the-art gene-based therapies: The road ahead
-
Kay, M.A. State-of-the-art gene-based therapies: The road ahead. Nat. Rev. Genet. 2011, 12, 316–328.
-
(2011)
Nat. Rev. Genet
, vol.12
, pp. 316-328
-
-
Kay, M.A.1
-
48
-
-
0036901290
-
Adenoviral vectors: Systemic delivery and tumor targeting
-
Green, N.K.; Seymour, L.W. Adenoviral vectors: Systemic delivery and tumor targeting. Cancer Gene Ther. 2002, 9, 1036–1042.
-
(2002)
Cancer Gene Ther
, vol.9
, pp. 1036-1042
-
-
Green, N.K.1
Seymour, L.W.2
-
49
-
-
0034722895
-
Onyx-015 selectivity and the p14arf pathway
-
McCormick, F. Onyx-015 selectivity and the p14arf pathway. Oncogene 2000, 19, 6670–6672.
-
(2000)
Oncogene
, vol.19
, pp. 6670-6672
-
-
McCormick, F.1
-
50
-
-
21344445274
-
Gene-directed enzyme prodrug therapy with carboxylesterase enhances the anticancer efficacy of the conditionally replicating adenovirus addelta24
-
Oosterhoff, D.; Pinedo, H.M.; Witlox, M.A.; Carette, J.E.; Gerritsen, W.R.; van Beusechem, V.W. Gene-directed enzyme prodrug therapy with carboxylesterase enhances the anticancer efficacy of the conditionally replicating adenovirus addelta24. Gene Ther. 2005, 12, 1011–1018.
-
(2005)
Gene Ther
, vol.12
, pp. 1011-1018
-
-
Oosterhoff, D.1
Pinedo, H.M.2
Witlox, M.A.3
Carette, J.E.4
Gerritsen, W.R.5
Van Beusechem, V.W.6
-
51
-
-
0031691257
-
Circular intermediates of recombinant adeno-associated virus have defined structural characteristics responsible for long-term episomal persistence in muscle tissue
-
Duan, D.; Sharma, P.; Yang, J.; Yue, Y.; Dudus, L.; Zhang, Y.; Fisher, K.J.; Engelhardt, J.F. Circular intermediates of recombinant adeno-associated virus have defined structural characteristics responsible for long-term episomal persistence in muscle tissue. J. Virol. 1998, 72, 8568–8577.
-
(1998)
J. Virol
, vol.72
, pp. 8568-8577
-
-
Duan, D.1
Sharma, P.2
Yang, J.3
Yue, Y.4
Dudus, L.5
Zhang, Y.6
Fisher, K.J.7
Engelhardt, J.F.8
-
52
-
-
48949120141
-
Recent developments in adeno-associated virus vector technology
-
Buning, H.; Perabo, L.; Coutelle, O.; Quadt-Humme, S.; Hallek, M. Recent developments in adeno-associated virus vector technology. J. Gene Med. 2008, 10, 717–733.
-
(2008)
J. Gene Med
, vol.10
, pp. 717-733
-
-
Buning, H.1
Perabo, L.2
Coutelle, O.3
Quadt-Humme, S.4
Hallek, M.5
-
53
-
-
33750715724
-
Fda approves use of bacteriophages to be added to meat and poultry products
-
Lang, L.H. Fda approves use of bacteriophages to be added to meat and poultry products. Gastroenterology 2006, 131, 1370, doi:10.1053/j.gastro.2006.10.012.
-
(2006)
Gastroenterology
, vol.131
, pp. 1370
-
-
Lang, L.H.1
-
54
-
-
33646034578
-
A hybrid vector for ligand-directed tumor targeting and molecular imaging
-
Hajitou, A.; Trepel, M.; Lilley, C.E.; Soghomonyan, S.; Alauddin, M.M.; Marini, F.C., 3rd; Restel, B.H.; Ozawa, M.G.; Moya, C.A.; Rangel, R.; et al. A hybrid vector for ligand-directed tumor targeting and molecular imaging. Cell 2006, 125, 385–398.
-
(2006)
Cell
, vol.125
, pp. 385-398
-
-
Hajitou, A.1
Trepel, M.2
Lilley, C.E.3
Soghomonyan, S.4
Alauddin, M.M.5
Marini, F.C.6
Restel, B.H.7
Ozawa, M.G.8
Moya, C.A.9
Rangel, R.10
-
55
-
-
34347255756
-
Design and construction of targeted aavp vectors for mammalian cell transduction
-
Hajitou, A.; Rangel, R.; Trepel, M.; Soghomonyan, S.; Gelovani, J.G.; Alauddin, M.M.; Pasqualini, R.; Arap, W. Design and construction of targeted aavp vectors for mammalian cell transduction. Nat. Protoc. 2007, 2, 523–531.
-
(2007)
Nat. Protoc
, vol.2
, pp. 523-531
-
-
Hajitou, A.1
Rangel, R.2
Trepel, M.3
Soghomonyan, S.4
Gelovani, J.G.5
Alauddin, M.M.6
Pasqualini, R.7
Arap, W.8
-
56
-
-
58949090367
-
Tumor vasculature-targeted delivery of tumor necrosis factor-alpha
-
Tandle, A.; Hanna, E.; Lorang, D.; Hajitou, A.; Moya, C.A.; Pasqualini, R.; Arap, W.; Adem, A.; Starker, E.; Hewitt, S.; et al. Tumor vasculature-targeted delivery of tumor necrosis factor-alpha. Cancer 2009, 115, 128–139.
-
(2009)
Cancer
, vol.115
, pp. 128-139
-
-
Tandle, A.1
Hanna, E.2
Lorang, D.3
Hajitou, A.4
Moya, C.A.5
Pasqualini, R.6
Arap, W.7
Adem, A.8
Starker, E.9
Hewitt, S.10
-
57
-
-
63749090726
-
Launching a novel preclinical infrastructure: Comparative oncology trials consortium directed therapeutic targeting of tnfalpha to cancer vasculature
-
Paoloni, M.C.; Tandle, A.; Mazcko, C.; Hanna, E.; Kachala, S.; Leblanc, A.; Newman, S.; Vail, D.; Henry, C.; Thamm, D.; et al. Launching a novel preclinical infrastructure: Comparative oncology trials consortium directed therapeutic targeting of tnfalpha to cancer vasculature. PLoS One 2009, 4, e4972.
-
(2009)
Plos One
, vol.4
-
-
Paoloni, M.C.1
Tandle, A.2
Mazcko, C.3
Hanna, E.4
Kachala, S.5
Leblanc, A.6
Newman, S.7
Vail, D.8
Henry, C.9
Thamm, D.10
-
58
-
-
68849090740
-
A heterotypic bystander effect for tumor cell killing after adeno-associated virus/phage-mediated, vascular-targeted suicide gene transfer
-
Trepel, M.; Stoneham, C.A.; Eleftherohorinou, H.; Mazarakis, N.D.; Pasqualini, R.; Arap, W.; Hajitou, A. A heterotypic bystander effect for tumor cell killing after adeno-associated virus/phage-mediated, vascular-targeted suicide gene transfer. Mol. Cancer Ther. 2009, 8, 2383–2391.
-
(2009)
Mol. Cancer Ther
, vol.8
, pp. 2383-2391
-
-
Trepel, M.1
Stoneham, C.A.2
Eleftherohorinou, H.3
Mazarakis, N.D.4
Pasqualini, R.5
Arap, W.6
Hajitou, A.7
-
59
-
-
0142154311
-
Inhibitors of DNA methylation and histone deacetylation activate cytomegalovirus promoter-controlled reporter gene expression in human glioblastoma cell line u87
-
Grassi, G.; Maccaroni, P.; Meyer, R.; Kaiser, H.; D’Ambrosio, E.; Pascale, E.; Grassi, M.; Kuhn, A.; di Nardo, P.; Kandolf, R.; et al. Inhibitors of DNA methylation and histone deacetylation activate cytomegalovirus promoter-controlled reporter gene expression in human glioblastoma cell line u87. Carcinogenesis 2003, 24, 1625–1635.
-
(2003)
Carcinogenesis
, vol.24
, pp. 1625-1635
-
-
Grassi, G.1
Maccaroni, P.2
Meyer, R.3
Kaiser, H.4
D’Ambrosio, E.5
Pascale, E.6
Grassi, M.7
Kuhn, A.8
Di Nardo, P.9
Kandolf, R.10
-
60
-
-
16544395591
-
DNA methylation and cancer
-
Das, P.M.; Singal, R. DNA methylation and cancer. J. Clin. Oncol. 2004, 22, 4632–4642.
-
(2004)
J. Clin. Oncol
, vol.22
, pp. 4632-4642
-
-
Das, P.M.1
Singal, R.2
-
61
-
-
0000346996
-
Molecular mechanism for silencing virally transduced genes involves histone deacetylation and chromatin condensation
-
Chen, W.Y.; Townes, T.M. Molecular mechanism for silencing virally transduced genes involves histone deacetylation and chromatin condensation. Proc. Natl. Acad. Sci. USA 2000, 97, 377–382.
-
(2000)
Proc. Natl. Acad. Sci. USA
, vol.97
, pp. 377-382
-
-
Chen, W.Y.1
Townes, T.M.2
-
62
-
-
84886050598
-
Inhibition of histone deacetylation and DNA methylation improves gene expression mediated by the adeno-associated virus/phage in cancer cells
-
Kia, A.; Yata, T.; Hajji, N.; Hajitou, A. Inhibition of histone deacetylation and DNA methylation improves gene expression mediated by the adeno-associated virus/phage in cancer cells. Viruses 2013, 5, 2561–2572.
-
(2013)
Viruses
, vol.5
, pp. 2561-2572
-
-
Kia, A.1
Yata, T.2
Hajji, N.3
Hajitou, A.4
-
63
-
-
78149466318
-
Targeted methylation of cmv and e1a viral promoters
-
Hsu, C.C.; Li, H.P.; Hung, Y.H.; Leu, Y.W.; Wu, W.H.; Wang, F.S.; Lee, K.D.; Chang, P.J.; Wu, C.S.; Lu, Y.J.; et al. Targeted methylation of cmv and e1a viral promoters. Biochem. Biophys. Res. Commun. 2010, 402, 228–234.
-
(2010)
Biochem. Biophys. Res. Commun
, vol.402
, pp. 228-234
-
-
Hsu, C.C.1
Li, H.P.2
Hung, Y.H.3
Leu, Y.W.4
Wu, W.H.5
Wang, F.S.6
Lee, K.D.7
Chang, P.J.8
Wu, C.S.9
Lu, Y.J.10
|