Transcriptional targeting of gene expression in breast cancer by the promoters of protein regulator of cytokinesis 1 and ribonuclease reductase 2

Experimental and Molecular Medicine

Volumn 40, Issue 3, 2008, Pages 345-353

  Hye, Jin Yun ^a   Cho, Young Hwa ^b   Moon, Youngsun ^a   Young, Woo Park ^c   Yoon, Hye Kyoung ^d   Kim, Yeun Ju ^b   Cho, Sung Ha ^b   Lee, Young Ill ^e   Kang, Bong Su ^b   Kim, Wun Jae ^f   Park, Keerang ^b   Seol, Wongi ^a  

^a Inje University   (South Korea)

^b Juseong College   (South Korea)

^c Korea Research Institute of Bioscience and Biotechnology (KRIBB)   (South Korea)

^d Inje University College of Medicine   (South Korea)

^e Suwon University   (South Korea)

^f Chungbuk National University College of Medicine   (South Korea)

Author keywords

Breast neoplasms; Gene therapy; PRC1 protein, human; Ribonucleotide reductase M2

Indexed keywords

COMPLEMENTARY DNA; GREEN FLUORESCENT PROTEIN; LUCIFERASE; OXIDOREDUCTASE; PARVOVIRUS VECTOR; PROTEIN; PROTEIN REGULATOR OF CYTOKINESIS 1; RIBONUCLEASE; RIBONUCLEASE REDUCTASE 2;

ARTICLE; BREAST CANCER; CANCER CELL CULTURE; CANCER GENE THERAPY; CELL STRAIN MCF 7; GENE EXPRESSION; GENE TARGETING; GENETIC TRANSDUCTION; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; MOLECULAR CLONING; NUCLEOTIDE SEQUENCE; PROMOTER REGION; REPORTER GENE; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TRANSCRIPTION REGULATION; VIRUS RECOMBINANT; WESTERN BLOTTING;

CYTOMEGALOVIRUS;

EID: 46449091470     PISSN: 12263613     EISSN: 20926413     Source Type: Journal    
DOI: 10.3858/emm.2008.40.3.345     Document Type: Article

References (36)

1. Ambrosini G, Adida C, Altieri DC. A novel anti-apoptosis gene, survivin, expressed in cancer and lymphoma. Nat Med 1997;3:917-21
2. Chen JS, Liu JC, Shen L, Rau KM, Kuo HP, Li YM, Shi D, Lee YC, Chang KJ, Hung MC. Cancer-specific activation of the survivin promoter and its potential use in gene therapy. Cancer Gene Ther 2004;11:740-7
3. Chien PY, Ito M, Park Y, Tagami T, Gehm BD, Jameson JL. A fusion protein of the estrogen receptor (ER) and nuclear receptor corepressor (NCoR) strongly inhibits estrogen-dependent responses in breast cancer cells. Mol Endocrinol 1999;13:2122-36
4. Cho YH, Park H, Cho ES, Kim WJ, Kang BS, Park BY, Kim YJ, Lee YI, Chang SI, Park K. A novel way of therapeutic angiogenesis using an adeno-associated virus-mediated angiogenin gene transfer. Exp Mol Med 2007;39:412-8
5. Dass CR, Choong PF. Selective gene delivery for cancer therapy using cationic liposomes: in vivo proof of applicability. J Control Release 2006;113:155-63
6. Dobson J. Gene therapy progress and prospects: magnetic nanoparticle-based gene delivery. Gene Ther 2006;13:283-7
7. Dong Z, Liu Y, Zhang JT. Regulation of ribonucleotide reductase M2 expression by the upstream AUGs. Nucleic Acids Res 2005;33:2715-25
8. Ealovega MW, McGinnis PK, Sumantran VN, Clarke MF, Wicha MS. bcl-xs gene therapy induces apoptosis of human mammary tumors in nude mice. Cancer Res 1996;56:1965-9
9. Eizuru Y, Inagawa S, Minamishima Y. Application of "Hirt supernatant" DNA to the molecular epidemiology of cytomegalovirus infections. J Clin Microbiol 1984;20:1012-4
10. El-Aneed A. An overview of current delivery systems in cancer gene therapy. J Control Release 2004;94:1-14
11. Engstrom Y, Eriksson S, Jildevik I, Skog S, Thelander L, Tribukait B. Cell cycle-dependent expression of mammalian ribonucleotide reductase. Differential regulation of the two subunits. J Biol Chem 1985;260:9114-6
12. Gu J, Kagawa S, Takakura M, Kyo S, Inoue M, Roth JA, Fang B. Tumor-specific transgene expression from the human telomerase reverse transcriptase promoter enables targeting of the therapeutic effects of the Bax gene to cancers. Cancer Res 2000;60:5359-64
13. Gu J, Zhang L, Huang X, Lin T, Yin M, Xu K, Ji L, Roth JA, Fang B. A novel single tetracycline-regulative adenoviral vector for tumor-specific Bax gene expression and cell killing in vitro and in vivo. Oncogene 2002;21:4757-64
14. Gu J, Fang B. Telomerase promoter-driven cancer gene therapy. Cancer Biol Ther 2003;2:S64-70
15. Jensen RA, Page DL, Holt JT. Identification of genes expressed in premalignant breast disease by microscopy-directed cloning. Proc Natl Acad Sci USA 1994;91:9257-61
16. Jeong H, Kim MS, Kim SW, Kim KS, Seol W. Regulation of tyrosine hydroxylase gene expression by retinoic acid receptor. J Neurochem 2006;98:386-94
17. Jiang S, Altmann A, Grimm D, Kleinschmidt JA, Schilling T, Germann C, Haberkorn U. Tissue-specific gene expression in medullary thyroid carcinoma cells employing calcitonin regulatory elements and AAV vectors. Cancer Gene Ther 2001;8:469-72
18. Kim NW, Piatyszek MA, Prowse KR, Harley CB, West MD, Ho PL, Coviello GM, Wright WE, Weinrich SL, Shay JW. Specific association of human telomerase activity with immortal cells and cancer. Science 1994;266: 2011-5
19. Kim SJ, Lee HS, Shin JH, Kim CG, Jeong S, Park K, Choe H, Lee H. Preferentially enhanced gene expression from a synthetic human telomerase reverse transcriptase promoter in human cancer cells. Oncol Rep 2006;16:975-9
20. Koga S, Hirohata S, Kondo Y, Komata T, Takakura M, Inoue M, Kyo S, Kondo S. FADD gene therapy using the human telomerase catalytic subunit (hTERT) gene promoter to restrict induction of apoptosis to tumors in vitro and in vivo. Anticancer Res 2001;21:1937-43
21. Lee HS, Shin OK, Kim SJ, Lee WI, Jeong S, Park K, Choe H, Lee H. Efficient gene expression by self-complementary adeno-associated virus serotype 2 and 5 in various human cancer cells. Oncol Rep 2007;18:611-6
22. Li C, Lin M, Liu J. Identification of PRC1 as the p53 target gene uncovers a novel function of p53 in the regulation of cytokinesis. Oncogene 2004;23:9336-47
23. Li C, Bowles DE, van Dyke TSamulski RJ. Adeno-associated virus vectors: potential applications for cancer gene therapy. Cancer Gene Ther 2005;12:913-25
24. Lin J, Page C, Jin X, Sethi AO, Patel R, Nunez G. Suppression activity of pro-apoptotic gene products in cancer cells, a potential application for cancer gene therapy. Anticancer Res 2001;21:831-9
25. Lo HW, Day CP, Hung MC. Cancer-specific gene therapy. Adv Genet 2005;54:235-55
26. Mollinari C, Kleman JP, Jiang W, Schoehn G, Hunter T, Margolis RL. PRC1 is a microtubule binding and bundling protein essential to maintain the mitotic spindle midzone. J Cell Biol 2002;157:1175-86
27. Nenoi M, Daino K, Ichimura S, Takahash S, Akuta T. Low-dose radiation response of the p21WAF1/CIP1 gene promoter transduced by adeno-associated virus vector. Exp Mol Med 2006;38:553-64
28. Park K, Cho YH, Kim WJ, Seol W, Cho ES, Kim YJ, Cho SH, Kim HJ, Kang BS, Ji WJ. Targeted cancer gene therapy using AAV2-mediated anti-angiogenesis approaches. Molecular Therapy 2007;15:S244
29. Park K, Kim WJ, Cho YH, Lee YI, Lee H, Jeong S, Cho ES, Chang SI, Moon SK, Kang BS, Kim YJ, Cho SH. Cancer gene therapy using adeno-associated virus vectors. Front Biosci 2008;2008:2653-9
30. Ruan H, Su H, Hu L, Lamborn KR, Kan YW, Deen DF. A hypoxia-regulated adeno-associated virus vector for cancer-specific gene therapy. Neoplasia 2001;3:255-63
31. Sharma MR, Koltowski L, Ownbey RT, Tuszynski GP, Sharma MC. Angiogenesis-associated protein annexin II in breast cancer: selective expression in invasive breast cancer and contribution to tumor invasion and progression. Exp Mol Pathol 2006;81:146-56
32. Sieger S, Jiang S, Kleinschmidt J, Eskerski H, Schonsiegel F, Altmann A, Mier W, Haberkorn U. Tumor-specific gene expression using regulatory elements of the glucose transporter isoform 1 gene. Cancer Gene Ther 2004;11:41-51
33. Su H, Chang JC, Xu SM, Kan YW. Selective killing of AFP-positive hepatocellular carcinoma cells by adeno-associated virus transfer of the herpes simplex virus thymidine kinase gene. Hum Gene Ther 1996;7:463-70
34. Su ZZ, Madireddi MT, Lin JJ, Young CS, Kitada S, Reed JC, Goldstein NI, Fisher PB. The cancer growth suppressor gene mda-7 selectively induces apoptosis in human breast cancer cells and inhibits tumor growth in nude mice. Proc Natl Acad Sci USA 1998;95:14400-5
35. Vojtesek B, Lane DP. Regulation of p53 protein expression in human breast cancer cell lines. J Cell Sci 1993;105 (Pt 3):607-12
36. Yang L, Cao Z, Li F, Post DE, Van Meir EG, Zhong H, Wood WC. Tumor-specific gene expression using the survivin promoter is further increased by hypoxia. Gene Ther 2004;11:1215-23