-
1
-
-
0032535999
-
Cancer treatment by targeted drug delivery to tumor vasculature in a mouse model
-
Arap W., Pasqualini R., Ruoslahti E. Cancer treatment by targeted drug delivery to tumor vasculature in a mouse model. Science 1998, 279:377-380.
-
(1998)
Science
, vol.279
, pp. 377-380
-
-
Arap, W.1
Pasqualini, R.2
Ruoslahti, E.3
-
2
-
-
18244407799
-
Steps toward mapping the human vasculature by phage display
-
Arap W., Kolonin M.G., Trepel M., et al. Steps toward mapping the human vasculature by phage display. Nat. Med. 2002, 8:121-127.
-
(2002)
Nat. Med.
, vol.8
, pp. 121-127
-
-
Arap, W.1
Kolonin, M.G.2
Trepel, M.3
-
3
-
-
0030847064
-
Bacteriophage therapy and prophylaxis: Rediscovery and renewed assessment of potential
-
Barrow P.A., Soothill J.S. Bacteriophage therapy and prophylaxis: Rediscovery and renewed assessment of potential. Trends Microbiol. 1997, 5:268-271.
-
(1997)
Trends Microbiol.
, vol.5
, pp. 268-271
-
-
Barrow, P.A.1
Soothill, J.S.2
-
4
-
-
31044452085
-
Enhancement of plasmid mediated gene therapy for muscular dystrophy by directed plasmid integration
-
Bertoni C., Jarrahian S., Wheeler T.M., et al. Enhancement of plasmid mediated gene therapy for muscular dystrophy by directed plasmid integration. Proc. Natl. Acad. Sci. USA 2006, 103:419-424.
-
(2006)
Proc. Natl. Acad. Sci. USA
, vol.103
, pp. 419-424
-
-
Bertoni, C.1
Jarrahian, S.2
Wheeler, T.M.3
-
5
-
-
68549087056
-
Viral vectors: From virology to transgene expression
-
Bouard D., Alazard-Dany N., Cosset F.L. Viral vectors: From virology to transgene expression. Br. J. Pharmcol. 2009, 157:153-165.
-
(2009)
Br. J. Pharmcol.
, vol.157
, pp. 153-165
-
-
Bouard, D.1
Alazard-Dany, N.2
Cosset, F.L.3
-
6
-
-
0028670833
-
vβ3 antagonists promote tumor regression by inducing apoptosis of angiogenic blood vessels
-
vβ3 antagonists promote tumor regression by inducing apoptosis of angiogenic blood vessels. Cell 1994, 79:1157-1164.
-
(1994)
Cell
, vol.79
, pp. 1157-1164
-
-
Brooks, P.C.1
Montgomery, A.M.2
Rosenfeld, M.3
-
7
-
-
48949120141
-
Recent developments in adeno-associated virus vector technology
-
Büning H., Perabo L., Coutelle O., et al. Recent developments in adeno-associated virus vector technology. J. Gene Med. 2008, 10:717-733.
-
(2008)
J. Gene Med.
, vol.10
, pp. 717-733
-
-
Büning, H.1
Perabo, L.2
Coutelle, O.3
-
8
-
-
0036202710
-
PET scanners dedicated to molecular imaging of small animal models
-
Chatziioannou A.F. PET scanners dedicated to molecular imaging of small animal models. Mol. Imaging Biol. 2002, 4:47-63.
-
(2002)
Mol. Imaging Biol.
, vol.4
, pp. 47-63
-
-
Chatziioannou, A.F.1
-
9
-
-
31144461091
-
Instrumentation for molecular imaging in preclinical research: Micro-PET and Micro-SPECT
-
Chatziioannou A.F. Instrumentation for molecular imaging in preclinical research: Micro-PET and Micro-SPECT. Proc. Am. Thorac. Soc. 2005, 2(533-536):510-511.
-
(2005)
Proc. Am. Thorac. Soc.
, vol.2
, Issue.533-536
, pp. 510-511
-
-
Chatziioannou, A.F.1
-
11
-
-
34848904829
-
Adenoviral vectors for gene therapy
-
Douglas J.T. Adenoviral vectors for gene therapy. Mol. Biotechnol. 2007, 36:71-80.
-
(2007)
Mol. Biotechnol.
, vol.36
, pp. 71-80
-
-
Douglas, J.T.1
-
12
-
-
0031691257
-
Circular intermediates of recombinant adeno-associated virus have defined structural characteristics responsible for long-term episomal persistence in muscle tissue
-
Duan D., Sharma P., Yang J., et al. Circular intermediates of recombinant adeno-associated virus have defined structural characteristics responsible for long-term episomal persistence in muscle tissue. J. Virol. 1998, 72:8568-8577.
-
(1998)
J. Virol.
, vol.72
, pp. 8568-8577
-
-
Duan, D.1
Sharma, P.2
Yang, J.3
-
13
-
-
0032819838
-
Anti-cancer activity of targeted pro-apoptotic peptides
-
Ellerby H.M., Arap W., Ellerby L.M., et al. Anti-cancer activity of targeted pro-apoptotic peptides. Nat. Med. 1999, 5:1032-1038.
-
(1999)
Nat. Med.
, vol.5
, pp. 1032-1038
-
-
Ellerby, H.M.1
Arap, W.2
Ellerby, L.M.3
-
14
-
-
0002501771
-
Principles and Practice of Oncology
-
Lippincott, Philadelphia, V.T. DeVita, S. Hellman, S.A. Rosenberg (Eds.)
-
Folkman J. Principles and Practice of Oncology. Cancer 1997, 3075-3085. Lippincott, Philadelphia. 5th edn. V.T. DeVita, S. Hellman, S.A. Rosenberg (Eds.).
-
(1997)
Cancer
, pp. 3075-3085
-
-
Folkman, J.1
-
15
-
-
0242385251
-
A mutant herpes simplex virus type 1 thymidine kinase reporter gene shows improved sensitivity for imaging reporter gene expression with positron emission tomography
-
Gambhir S.S., Bauer E., Black M.E., et al. A mutant herpes simplex virus type 1 thymidine kinase reporter gene shows improved sensitivity for imaging reporter gene expression with positron emission tomography. Proc. Natl. Acad. Sci. USA 2000, 97:2785-2790.
-
(2000)
Proc. Natl. Acad. Sci. USA
, vol.97
, pp. 2785-2790
-
-
Gambhir, S.S.1
Bauer, E.2
Black, M.E.3
-
16
-
-
27144493705
-
Selection of muscle-binding peptides from context-specific peptide-presenting phage libraries for adenoviral vector targeting
-
Gosh D., Barry M.A. Selection of muscle-binding peptides from context-specific peptide-presenting phage libraries for adenoviral vector targeting. J. Virol. 2005, 79:13667-13672.
-
(2005)
J. Virol.
, vol.79
, pp. 13667-13672
-
-
Gosh, D.1
Barry, M.A.2
-
17
-
-
0036901290
-
Adenoviral vectors: Systemic delivery and tumor targeting
-
Green N.K., Seymour L.W. Adenoviral vectors: Systemic delivery and tumor targeting. Cancer Gene Ther. 2002, 9:1036-1042.
-
(2002)
Cancer Gene Ther.
, vol.9
, pp. 1036-1042
-
-
Green, N.K.1
Seymour, L.W.2
-
18
-
-
4043092073
-
Systemic delivery of genes to striated muscles using adeno-associated viral vectors
-
Gregorevic P., Blankinship M.J., Allen J.M., et al. Systemic delivery of genes to striated muscles using adeno-associated viral vectors. Nat. Med. 2004, 10:828-834.
-
(2004)
Nat. Med.
, vol.10
, pp. 828-834
-
-
Gregorevic, P.1
Blankinship, M.J.2
Allen, J.M.3
-
19
-
-
33644994202
-
Vascular targeting: Recent advances, and therapeutic perspectives
-
Hajitou A., Pasqualini R., Arap W. Vascular targeting: Recent advances, and therapeutic perspectives. Trends Cardiovasc. Med. 2006, 16:80-88.
-
(2006)
Trends Cardiovasc. Med.
, vol.16
, pp. 80-88
-
-
Hajitou, A.1
Pasqualini, R.2
Arap, W.3
-
20
-
-
33646034578
-
A hybrid vector for ligand-directed tumor targeting and molecular imaging
-
Hajitou A., Trepel M., Lilley C.E., et al. A hybrid vector for ligand-directed tumor targeting and molecular imaging. Cell 2006, 125:385-398.
-
(2006)
Cell
, vol.125
, pp. 385-398
-
-
Hajitou, A.1
Trepel, M.2
Lilley, C.E.3
-
21
-
-
34347255756
-
Design and construction of targeted AAVP vectors for mammalian cell transduction
-
Hajitou A., Rangel R., Trepel M., et al. Design and construction of targeted AAVP vectors for mammalian cell transduction. Nat. Protoc. 2007, 2:523-531.
-
(2007)
Nat. Protoc.
, vol.2
, pp. 523-531
-
-
Hajitou, A.1
Rangel, R.2
Trepel, M.3
-
22
-
-
41949106969
-
A preclinical model for predicting drug response in soft-tissue sarcoma with targeted AAVP molecular imaging
-
Hajitou A., Levy D.C., Hannay J.A.F., et al. A preclinical model for predicting drug response in soft-tissue sarcoma with targeted AAVP molecular imaging. Proc. Natl. Acad. Sci. USA 2008, 105:4471-4476.
-
(2008)
Proc. Natl. Acad. Sci. USA
, vol.105
, pp. 4471-4476
-
-
Hajitou, A.1
Levy, D.C.2
Hannay, J.A.F.3
-
23
-
-
0033576564
-
Evolution: The long evolutionary reach of viruses
-
Hendrix R.W. Evolution: The long evolutionary reach of viruses. Curr. Biol. 1999, 9:R914-R917.
-
(1999)
Curr. Biol.
, vol.9
-
-
Hendrix, R.W.1
-
24
-
-
16844381577
-
A new perspective on tumor endothelial cells: Unexpected chromosome and centrosome abnormalities
-
Hida K., Klagsburn M. A new perspective on tumor endothelial cells: Unexpected chromosome and centrosome abnormalities. Cancer Res. 2005, 65:2507-2510.
-
(2005)
Cancer Res.
, vol.65
, pp. 2507-2510
-
-
Hida, K.1
Klagsburn, M.2
-
25
-
-
0037189380
-
Tumor regression by targeted gene delivery to the neovasculature
-
Hood J.D., Bednarski M., Frausto R., et al. Tumor regression by targeted gene delivery to the neovasculature. Science 2002, 296:2404-2407.
-
(2002)
Science
, vol.296
, pp. 2404-2407
-
-
Hood, J.D.1
Bednarski, M.2
Frausto, R.3
-
26
-
-
0035300468
-
Positron emission tomography-based imaging of transgene expression mediated by replication-conditional, oncolytic herpes simplex virus type 1 mutant vectors in vivo
-
Jacobs A., Tjuvajev J.G., Dubrovin M., et al. Positron emission tomography-based imaging of transgene expression mediated by replication-conditional, oncolytic herpes simplex virus type 1 mutant vectors in vivo. Cancer Res. 2001, 61:2983-2995.
-
(2001)
Cancer Res.
, vol.61
, pp. 2983-2995
-
-
Jacobs, A.1
Tjuvajev, J.G.2
Dubrovin, M.3
-
27
-
-
32044438650
-
Positronemission tomography and assessment of cancer therapy
-
Juweid M.E., Cheson B.D. Positronemission tomography and assessment of cancer therapy. N. Engl. J. Med. 2006, 354:496-507.
-
(2006)
N. Engl. J. Med.
, vol.354
, pp. 496-507
-
-
Juweid, M.E.1
Cheson, B.D.2
-
28
-
-
19944430000
-
Noninvasive dual modality in vivo monitoring of the persistence and potency of a tumor targeted conditionally replicating adenovirus
-
Kanerva A., Zinn K.R., Peng K.W., et al. Noninvasive dual modality in vivo monitoring of the persistence and potency of a tumor targeted conditionally replicating adenovirus. Gene Ther. 2005, 12:87-94.
-
(2005)
Gene Ther.
, vol.12
, pp. 87-94
-
-
Kanerva, A.1
Zinn, K.R.2
Peng, K.W.3
-
29
-
-
33646787078
-
3H]PCV for monitoring reporter gene expression of wild type and mutant Herpes simplex virus type 1 thymidine kinase in cell culture
-
3H]PCV for monitoring reporter gene expression of wild type and mutant Herpes simplex virus type 1 thymidine kinase in cell culture. Mol. Imaging Biol. 2005, 7:296-303.
-
(2005)
Mol. Imaging Biol.
, vol.7
, pp. 296-303
-
-
Kang, K.W.1
Min, J.J.2
Chen, X.3
Gambhir, S.S.4
-
30
-
-
0033831080
-
A controlled trial of intratumoral ONYX-015, a selectively-replicating adenovirus, in combination with cisplatin and 5-fluorouracil in patients with recurrent head and neck cancer
-
Khuri F.R., Nemunaitis J., Ganly I., et al. A controlled trial of intratumoral ONYX-015, a selectively-replicating adenovirus, in combination with cisplatin and 5-fluorouracil in patients with recurrent head and neck cancer. Nat. Med. 2000, 6:879-885.
-
(2000)
Nat. Med.
, vol.6
, pp. 879-885
-
-
Khuri, F.R.1
Nemunaitis, J.2
Ganly, I.3
-
31
-
-
0032211231
-
Targeting bacteriophage to mammalian cell surface receptors for gene delivery
-
Larocca D., Witte A., Johnson W., et al. Targeting bacteriophage to mammalian cell surface receptors for gene delivery. Hum. Gene Ther. 1998, 9:2393-2399.
-
(1998)
Hum. Gene Ther.
, vol.9
, pp. 2393-2399
-
-
Larocca, D.1
Witte, A.2
Johnson, W.3
-
32
-
-
10744220098
-
Aminopeptidase A is a functional target in angiogenic blood vessels
-
Marchiò S., Lahdenranta J., Schlingemann R.O., et al. Aminopeptidase A is a functional target in angiogenic blood vessels. Cancer Cell 2004, 5:151-162.
-
(2004)
Cancer Cell
, vol.5
, pp. 151-162
-
-
Marchiò, S.1
Lahdenranta, J.2
Schlingemann, R.O.3
-
33
-
-
27744597379
-
Topical application of plasmid DNA to mouse and human skin
-
Meykadeh N., Mirmohammadsadegh A., Wang Z., et al. Topical application of plasmid DNA to mouse and human skin. J. Mol. Med. 2005, 83:897-903.
-
(2005)
J. Mol. Med.
, vol.83
, pp. 897-903
-
-
Meykadeh, N.1
Mirmohammadsadegh, A.2
Wang, Z.3
-
34
-
-
0033950285
-
Adenovirus-mediated p53 gene transfer in sequence with cisplatin to tumors of patients with non-small-cell lung cancer
-
Nemunaitis J., Swisher S.G., Timmons T., et al. Adenovirus-mediated p53 gene transfer in sequence with cisplatin to tumors of patients with non-small-cell lung cancer. J. Clin. Oncol. 2000, 18:609-622.
-
(2000)
J. Clin. Oncol.
, vol.18
, pp. 609-622
-
-
Nemunaitis, J.1
Swisher, S.G.2
Timmons, T.3
-
35
-
-
21344445274
-
Gene-directed enzyme prodrug therapy with carboxylesterase enhances the anticancer efficacy of the conditionally replicating adenovirus AdDelta24
-
Oosterhoff D., Pinedo H.M., Witlox M.A., et al. Gene-directed enzyme prodrug therapy with carboxylesterase enhances the anticancer efficacy of the conditionally replicating adenovirus AdDelta24. Gene Ther. 2005, 12:1011-1018.
-
(2005)
Gene Ther.
, vol.12
, pp. 1011-1018
-
-
Oosterhoff, D.1
Pinedo, H.M.2
Witlox, M.A.3
-
36
-
-
63749090726
-
Launching a Novel Preclinical Infrasturcture: Comparative Oncology Trials Consortium Directed Therapeutic Targeting of TNF-α to Cancer Vasculature
-
Paoloni M., Tandle A., Mazcko C., et al. Launching a Novel Preclinical Infrasturcture: Comparative Oncology Trials Consortium Directed Therapeutic Targeting of TNF-α to Cancer Vasculature. PLoS One 2009, 4:e4972.
-
(2009)
PLoS One
, vol.4
-
-
Paoloni, M.1
Tandle, A.2
Mazcko, C.3
-
37
-
-
0029932458
-
Organ targeting in vivo using phage display peptide libraries
-
Pasqualini R., Ruoslahti E. Organ targeting in vivo using phage display peptide libraries. Nature 1996, 380:364-366.
-
(1996)
Nature
, vol.380
, pp. 364-366
-
-
Pasqualini, R.1
Ruoslahti, E.2
-
38
-
-
0033950895
-
Aminopeptidase N is a receptor for tumor-homing peptides and a target for inhibiting angiogenesis
-
Pasqualini R., Koivunen E., Kain R., et al. Aminopeptidase N is a receptor for tumor-homing peptides and a target for inhibiting angiogenesis. Cancer Res. 2000, 60:722-727.
-
(2000)
Cancer Res.
, vol.60
, pp. 722-727
-
-
Pasqualini, R.1
Koivunen, E.2
Kain, R.3
-
39
-
-
33750715724
-
FDA approves use of bacteriophages to be added to meat and poultry products
-
Peek R., Reddy K.R. FDA approves use of bacteriophages to be added to meat and poultry products. Gastroenterology 2006, 131:1370-1372.
-
(2006)
Gastroenterology
, vol.131
, pp. 1370-1372
-
-
Peek, R.1
Reddy, K.R.2
-
40
-
-
22944478652
-
Transcriptionally targeted adenovirus vectors
-
Sadeghi H., Hitt M.M. Transcriptionally targeted adenovirus vectors. Curr. Gene Ther. 2005, 5:411-427.
-
(2005)
Curr. Gene Ther.
, vol.5
, pp. 411-427
-
-
Sadeghi, H.1
Hitt, M.M.2
-
41
-
-
0023216839
-
A recombinant plasmid from which an infectious adeno-associated virus genome can be excised in vitro and its use to study viral replication
-
Samulski R.J., Chang L.S., Shenk T. A recombinant plasmid from which an infectious adeno-associated virus genome can be excised in vitro and its use to study viral replication. J. Virol. 1987, 61:3096-3101.
-
(1987)
J. Virol.
, vol.61
, pp. 3096-3101
-
-
Samulski, R.J.1
Chang, L.S.2
Shenk, T.3
-
42
-
-
10844239971
-
Positron emission tomography (PET) imaging of tumor-localized Salmonella expressing HSV1-TK
-
Soghomonyan S., Doubrovin M., Pike J., et al. Positron emission tomography (PET) imaging of tumor-localized Salmonella expressing HSV1-TK. Cancer Gene Ther. 2005, 12:101-108.
-
(2005)
Cancer Gene Ther.
, vol.12
, pp. 101-108
-
-
Soghomonyan, S.1
Doubrovin, M.2
Pike, J.3
-
43
-
-
58949090367
-
Tumor vasculature targeted delivery of tumor necrosis factor-alpha
-
Tandle A., Hanna E., Lorang D., et al. Tumor vasculature targeted delivery of tumor necrosis factor-alpha. Cancer 2009, 115:128-139.
-
(2009)
Cancer
, vol.115
, pp. 128-139
-
-
Tandle, A.1
Hanna, E.2
Lorang, D.3
-
44
-
-
9544242826
-
Noninvasive imaging of herpes virus thymidine kinase gene transfer and expression: A potential method for monitoring clinical gene therapy
-
Tjuvajev J.G., Finn R., Watanabe K., et al. Noninvasive imaging of herpes virus thymidine kinase gene transfer and expression: A potential method for monitoring clinical gene therapy. Cancer Res. 1996, 56:4087-4095.
-
(1996)
Cancer Res.
, vol.56
, pp. 4087-4095
-
-
Tjuvajev, J.G.1
Finn, R.2
Watanabe, K.3
-
45
-
-
0036603896
-
In vivo phage display and vascular heterogeneity: Implications for targeted medicine
-
Trepel M., Arap W., Pasqualini R. In vivo phage display and vascular heterogeneity: Implications for targeted medicine. Curr. Opin. Chem. Biol. 2002, 6:399-404.
-
(2002)
Curr. Opin. Chem. Biol.
, vol.6
, pp. 399-404
-
-
Trepel, M.1
Arap, W.2
Pasqualini, R.3
-
46
-
-
68849090740
-
A heterotypic bystander effect for tumor cell killing after AAVP-mediated vascular targeted suicide gene transfer
-
Trepel M., Stoneham C.A., Eleftherohorinou H., et al. A heterotypic bystander effect for tumor cell killing after AAVP-mediated vascular targeted suicide gene transfer. Mol. Cancer Ther. 2009, 8:2383-2391.
-
(2009)
Mol. Cancer Ther.
, vol.8
, pp. 2383-2391
-
-
Trepel, M.1
Stoneham, C.A.2
Eleftherohorinou, H.3
-
47
-
-
34447535345
-
Engineering targeted viral vectors for gene therapy
-
Waehler R., Russell S.J., Curiel D.T. Engineering targeted viral vectors for gene therapy. Nat. Rev. Genet. 2007, 8:573-587.
-
(2007)
Nat. Rev. Genet.
, vol.8
, pp. 573-587
-
-
Waehler, R.1
Russell, S.J.2
Curiel, D.T.3
-
48
-
-
19644378907
-
Adeno-associated virus serotype 8 efficiently delivers genes to muscle and heart
-
Wang Z., Zhu T., Qiao C., et al. Adeno-associated virus serotype 8 efficiently delivers genes to muscle and heart. Nat. Biotechnol. 2005, 23:321-328.
-
(2005)
Nat. Biotechnol.
, vol.23
, pp. 321-328
-
-
Wang, Z.1
Zhu, T.2
Qiao, C.3
-
49
-
-
34249276065
-
Sustained AAV-mediated dystrophin expression in a canine model of Duchenne muscular dystrophy with a brief course of immunosuppression
-
Wang Z., Kuhr C.S., Allen J.M., et al. Sustained AAV-mediated dystrophin expression in a canine model of Duchenne muscular dystrophy with a brief course of immunosuppression. Mol. Ther. 2007, 15:1160-1166.
-
(2007)
Mol. Ther.
, vol.15
, pp. 1160-1166
-
-
Wang, Z.1
Kuhr, C.S.2
Allen, J.M.3
-
50
-
-
0036359767
-
Scaling down imaging: Molecular mapping of cancer in mice
-
Weissleder R. Scaling down imaging: Molecular mapping of cancer in mice. Nat. Rev. Cancer 2002, 2:11-18.
-
(2002)
Nat. Rev. Cancer
, vol.2
, pp. 11-18
-
-
Weissleder, R.1
|