One-week intervention period led to improvements in glycemic control and reduction in DNA damage levels in patients with type 2 diabetes mellitus

Diabetes Research and Clinical Practice

Volumn 105, Issue 3, 2014, Pages 356-363

  Xavier, Danilo J ^a   Takahashi, Paula ^a   Manoel Caetano, Fernanda S ^a   Foss Freitas, Maria C ^a   Foss, Milton C ^a   Donadi, Eduardo A ^a   Passos, Geraldo A ^a   Sakamoto Hojo, Elza T ^a  

^a UNIVERSITY OF SÃO PAULO   (Brazil)

Author keywords

Comet assay; Hyperglycemia; Oxidative stress; PCR array; Type 2 diabetes mellitus

Indexed keywords

ADULT; ALKALINE COMET ASSAY; ANTIOXIDANT ACTIVITY; ARTICLE; BLOOD SAMPLING; CLINICAL ARTICLE; COMET ASSAY; CONTROLLED STUDY; DIET THERAPY; DNA DAMAGE; FEMALE; GENE EXPRESSION; GENETIC TRANSCRIPTION; GLUCOSE BLOOD LEVEL; GLYCEMIC CONTROL; HUMAN; INTERMETHOD COMPARISON; LENGTH OF STAY; MALE; MIDDLE AGED; NON INSULIN DEPENDENT DIABETES MELLITUS; OXIDATIVE STRESS; REAL TIME POLYMERASE CHAIN REACTION; TREATMENT DURATION; ANALYSIS; BLOOD; DIABETES MELLITUS, TYPE 2; GENE EXPRESSION PROFILING; GENETICS; HOSPITALIZATION; HYPERGLYCEMIA;

GLUCOSE BLOOD LEVEL; REACTIVE OXYGEN METABOLITE;

ADULT; BLOOD GLUCOSE; DIABETES MELLITUS, TYPE 2; DNA DAMAGE; FEMALE; GENE EXPRESSION PROFILING; HOSPITALIZATION; HUMANS; HYPERGLYCEMIA; MALE; MIDDLE AGED; OXIDATIVE STRESS; REACTIVE OXYGEN SPECIES;

EID: 84921692658     PISSN: 01688227     EISSN: 18728227     Source Type: Journal    
DOI: 10.1016/j.diabres.2014.06.004     Document Type: Article

References (35)

1. Bloomgarden Z.T. American Diabetes Association Annual Meeting, 1997. Type 2 diabetes. Diabetes Care 2012, 20:1791-1795.
2. Marx J. Unraveling the causes of diabetes. Science 2002, 296:686-689.
3. Brownlee M. Biochemistry and molecular cell biology of diabetic complications. Nature 2001, 414:813-820.
4. Guariguata L., Whiting D.R., Hambleton I., Beagley J., Linnenkamp U., Shaw J.E. Global estimates of diabetes prevalence in adults for 2013 and projections for 2035 for the IDF Diabetes Atlas. Diabetes Res Clin Pract 2014, 103(2):137-149.
5. Hardoon S.L., Morris R.W., Thomas M.C., Wannamethee S.G., Lennon L.T., Whincup P.H. Is the recent rise in type 2 diabetes incidence from 1984 to 2007 explained by the trend in increasing BMI?.: evidence from a prospective study of British men. Diabetes Care 2010, 33:1494-1496.
6. Allen D.A., Yaqoob M.M., Harwood S.M. Mechanisms of high glucose-induced apoptosis and its relationship to diabetic complications. J Nutr Biochem 2005, 16:705-713.
7. Niedowicz D.M., Daleke D.L. The role of oxidative stress in diabetic complications. Cell Biochem Biophys 2005, 43:289-330.
8. Catherwood M.A., Powell L.A., Anderson P., McMaster D., Sharpe P.C., Trimble E.R. Glucose-induced oxidative stress in mesangial cells. Kidney Int 2002, 61:599-608.
9. Lodovici M., Giovannelli L., Pitozzi V., Bigagli E., Bardini G., Rotella C.M. Oxidative DNA damage and plasma antioxidant capacity in type 2 diabetic patients with good and poor glycaemic control. Mutat Res 2008, 638:98-102.
10. Dincer Y., Akcay T., Alademir Z., Ilkova H. Assessment of DNA base oxidation and glutathione level in patients with type 2 diabetes. Mutat Res 2002, 505:75-81.
11. Manoel-Caetano F.S., Xavier D.J., Evangelista A.F., Takahashi P., Collares C.V., Puthier D., et al. Gene expression profiles displayed by peripheral blood mononuclear cells from patients with type 2 diabetes mellitus focusing on biological processes implicated on the pathogenesis of the disease. Gene 2012, 511:151-160.
12. Lee H.C., Wei Y.H. Oxidative stress, mitochondrial DNA mutation, and apoptosis in aging. Exp Biol Med (Maywood, NJ) 2007, 232:592-606.
13. Neeley W.L., Essigmann J.M. Mechanisms of formation, genotoxicity, and mutation of guanine oxidation products. Chem Res Toxicol 2006, 19:491-505.
14. Collins A.R. Investigating oxidative DNA damage and its repair using the comet assay. Mutat Res 2009, 681:24-32.
15. Blasiak J., Arabski M., Krupa R., Wozniak K., Zadrozny M., Kasznicki J., et al. DNA damage and repair in type 2 diabetes mellitus. Mutat Res 2004, 554:297-304.
16. Pan H.Z., Chang D., Feng L.G., Xu F.J., Kuang H.Y., Lu M.J. Oxidative damage to DNA and its relationship with diabetic complications. Biomed Environ Sci 2007, 20:160-163.
17. Sheetz M.J., King G.L. Molecular understanding of hyperglycemia's adverse effects for diabetic complications. JAMA 2002, 288:2579-2588.
18. Singh N.P., McCoy M.T., Tice R.R., Schneider E.L. A simple technique for quantitation of low levels of DNA damage in individual cells. Exp Cell Res 1988, 175:184-191.
19. Smith C.C., O'Donovan M.R. Martin EA. hOGG1 recognizes oxidative damage using the comet assay with greater specificity than FPG or ENDOIII. Mutagenesis 2006, 21:185-190.
20. Tice R.R., Agurell E., Anderson D., Burlinson B., Hartmann A., Kobayashi H., et al. Single cell gel/comet assay: guidelines for in vitro and in vivo genetic toxicology testing. Environ Mol Mutagen 2000, 35:206-221.
21. Tatsch E., Bochi G.V., Piva S.J., De Carvalho J.A., Kober H., Torbitz V.D., et al. Association between DNA strand breakage and oxidative, inflammatory and endothelial biomarkers in type 2 diabetes. Mutat Res 2012, 732:16-20.
22. Choi S.W., Yeung V.T., Benzie I.F. Heme oxygenase microsatellite polymorphism, oxidative stress, glycemic control, and complication development in type 2 diabetes patients. Free Radical Biol Med 2012, 53:60-63.
23. Baynes J.W. Role of oxidative stress in development of complications in diabetes. Diabetes 1991, 40:405-412.
24. Adaikalakoteswari A., Rema M., Mohan V., Balasubramanyam M. Oxidative DNA damage and augmentation of poly(ADP-ribose) polymerase/nuclear factor-kappa B signaling in patients with type 2 diabetes and microangiopathy. Int J Biochem Cell Biol 2007, 39:1673-1684.
25. van Loon B., Markkanen E., Hubscher U. Oxygen as a friend and enemy: how to combat the mutational potential of 8-oxo-guanine. DNA Repair (Amst) 2010, 9:604-616.
26. Bohr V.A. Repair of oxidative DNA damage in nuclear and mitochondrial DNA, and some changes with aging in mammalian cells. Free Radical Biol Med 2002, 32:804-812.
27. Collins A.R., Raslova K., Somorovska M., Petrovska H., Ondrusova A., Vohnout B., et al. DNA damage in diabetes: correlation with a clinical marker. Free Radical Biol Med 1998, 25:373-377.
28. Rosenquist T.A., Zharkov D.O., Grollman A.P. Cloning and characterization of a mammalian 8-oxoguanine DNA glycosylase. Proc Nat Acad Sci USA 1997, 94:7429-7434.
29. Garattini E., Fratelli M., Terao M. Mammalian aldehyde oxidases: genetics, evolution and biochemistry. Cell Mol Life Sci 2008, 65:1019-1048.
30. Weigert J., Neumeier M., Bauer S., Mages W., Schnitzbauer A.A., Obed A., et al. Small-interference RNA-mediated knock-down of aldehyde oxidase 1 in 3T3-L1 cells impairs adipogenesis and adiponectin release. FEBS Lett 2008, 582:2965-2972.
31. Zhou X., Taghizadeh K., Dedon P.C. Chemical and biological evidence for base propenals as the major source of the endogenous M1dG adduct in cellular DNA. J Biol Chem 2005, 280:25377-25382.
32. Kundu T.K., Hille R., Velayutham M., Zweier J.L. Characterization of superoxide production from aldehyde oxidase: an important source of oxidants in biological tissues. Arch Biochem Biophys 2007, 460:113-121.
33. Triqueneaux G., Velten M., Franzon P., Dautry F., Jacquemin-Sablon H. RNA binding specificity of Unr, a protein with five cold shock domains. Nucleic Acids Res 1999, 27:1926-1934.
34. Boussadia O., Niepmann M., Creancier L., Prats A.C., Dautry F., Jacquemin-Sablon H. Unr is required in vivo for efficient initiation of translation from the internal ribosome entry sites of both rhinovirus and poliovirus. J Virol 2003, 77:3353-3359.
35. Dormoy-Raclet V., Markovits J., Malato Y., Huet S., Lagarde P., Montaudon D., et al. Unr, a cytoplasmic RNA-binding protein with cold-shock domains, is involved in control of apoptosis in ES and HuH7 cells. Oncogene 2007, 26:2595-2605.