Early effect of tidal volume on lung injury biomarkers in surgical patients with healthy lungs

Anesthesiology

Volumn 121, Issue 3, 2014, Pages 469-481

  Fernandez Bustamante, Ana ^a   Klawitter, Jelena ^a   Repine, John E ^a   Agazio, Amanda ^a   Janocha, Allison J ^b   Shah, Chirag ^c   Moss, Marc ^a   Douglas, Ivor S ^a   Vu Tran, Zung ^d   Erzurum, Serpil C ^b   Christians, Uwe ^a   Seres, Tamas ^a  

^a UNIVERSITY OF COLORADO SCHOOL OF MEDICINE   (United States)

^b CASE WESTERN RESERVE UNIVERSITY   (United States)

^c CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d Global Health and Health Disparities   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL MARKER; CLARA CELL PROTEIN; CLARA CELL PROTEIN 16; INTERLEUKIN 10; INTERLEUKIN 11; INTERLEUKIN 1BETA; INTERLEUKIN 6; INTERLEUKIN 8; LEUKOCYTE ELASTASE; NITRATE; NITRITE; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; CYTOKINE; NITRIC ACID DERIVATIVE; NITRIC OXIDE; SCGB1A1 PROTEIN, HUMAN; UTEROGLOBIN;

ADULT; ARTIFICIAL VENTILATION; BLOOD SAMPLING; BODY WEIGHT; BREATHING RATE; CLINICAL ARTICLE; CONFERENCE PAPER; CONTROLLED STUDY; ENZYME BLOOD LEVEL; EXHALATION; FEMALE; GENERAL ANESTHESIA; HUMAN; KNEE ARTHROPLASTY; LUNG COMPLIANCE; LUNG INJURY; LUNG MINUTE VOLUME; MALE; POSITIVE END EXPIRATORY PRESSURE; PRIORITY JOURNAL; PROSPECTIVE STUDY; RANDOMIZED CONTROLLED TRIAL; RISK FACTOR; SURGICAL PATIENT; TIDAL VOLUME; AGED; BLOOD; METABOLISM; MIDDLE AGED;

AGED; ARTHROPLASTY, REPLACEMENT, KNEE; BIOLOGICAL MARKERS; CYTOKINES; FEMALE; HUMANS; LUNG INJURY; MALE; MIDDLE AGED; NITRATES; NITRIC OXIDE; NITRITES; PROSPECTIVE STUDIES; RESPIRATION, ARTIFICIAL; TIDAL VOLUME; UTEROGLOBIN;

EID: 84921692536     PISSN: 00033022     EISSN: 15281175     Source Type: Journal    
DOI: 10.1097/ALN.0000000000000301     Document Type: Conference Paper

References (74)

1. Lellouche F, Dionne S, Simard S, Bussières J, Dagenais F: High tidal volumes in mechanically ventilated patients increase organ dysfunction after cardiac surgery. Anesthesiology 2012; 116:1072-82.
2. Korovesi I, Papadomichelakis E, Orfanos SE, Giamarellos- Bourboulis EJ, Livaditi O, Pelekanou A, Sotiropoulou C, Koutsoukou A, Dimopoulou I, Ekonomidou F, Psevdi E, Armaganidis A, Roussos C, Marczin N, Kotanidou A: Exhaled breath condensate in mechanically ventilated brain-injured patients with no lung injury or sepsis. Anesthesiology 2011; 114:1118-29.
3. Pinheiro de Oliveira R, Hetzel MP, dos Anjos Silva M, Dallegrave D, Friedman G: Mechanical ventilation with high tidal volume induces inflammation in patients without lung disease. Crit Care 2010; 14: R39.
4. Gajic O, Dara SI, Mendez JL, Adesanya AO, Festic E, Caples SM, Rana R, St. Sauver JL, Lymp JF, Afessa B, Hubmayr RD: Ventilator-associated lung injury in patients without acute lung injury at the onset of mechanical ventilation. Crit Care Med 2004; 32:1817-24.
5. Altemeier WA, Matute-Bello G, Frevert CW, Kawata Y, Kajikawa O, Martin TR, Glenny RW: Mechanical ventilation with moderate tidal volumes synergistically increases lung cytokine response to systemic endotoxin. Am J Physiol Lung Cell Mol Physiol 2004; 287:L533-42.
6. Gessner C, Hammerschmidt S, Kuhn H, Lange T, Engelmann L, Schauer J, Wirtz H: Exhaled breath condensate nitrite and its relation to tidal volume in acute lung injury. Chest 2003; 124:1046-52.
7. ARDSNet: Ventilation with lower tidal volumes as compared with traditional tidal volumes for acute lung injury and the acute respiratory distress syndrome. The Acute Respiratory Distress Syndrome Network. N Engl J Med 2000; 342:1301-8.
8. Amato MB, Barbas CS, Medeiros DM, Magaldi RB, Schettino GP, Lorenzi-Filho G, Kairalla RA, Deheinzelin D, Munoz C, Oliveira R, Takagaki TY, Carvalho CR: Effect of a protectiveventilation strategy on mortality in the acute respiratory distress syndrome. N Engl J Med 1998; 338:347-54.
9. Futier E, Constantin JM, Paugam-Burtz C, Pascal J, Eurin M, Neuschwander A, Marret E, Beaussier M, Gutton C, Lefrant JY, Allaouchiche B, Verzilli D, Leone M, De Jong A, Bazin JE, Pereira B, Jaber S; IMPROVE Study Group: A trial of intraoperative low-tidal-volume ventilation in abdominal surgery. N Engl J Med 2013; 369:428-37.
10. Severgnini P, Selmo G, Lanza C, Chiesa A, Frigerio A, Bacuzzi A, Dionigi G, Novario R, Gregoretti C, de Abreu MG, Schultz MJ, Jaber S, Futier E, Chiaranda M, Pelosi P: Protective mechanical ventilation during general anesthesia for open abdominal surgery improves postoperative pulmonary function. Anesthesiology 2013; 118:1307-21.
11. Serpa Neto A, Cardoso SO, Manetta JA, Pereira VG, Espósito DC, Pasqualucci Mde O, Damasceno MC, Schultz MJ: Association between use of lung-protective ventilation with lower tidal volumes and clinical outcomes among patients without acute respiratory distress syndrome: A meta-analysis. JAMA 2012; 308:1651-9.
12. Fernandez-Bustamante A, Wood CL, Tran ZV, Moine P: Intraoperative ventilation: Incidence and risk factors for receiving large tidal volumes during general anesthesia. BMC Anesthesiol 2011; 11:22.
13. Canet J, Gallart L, Gomar C, Paluzie G, Vallès J, Castillo J, Sabaté S, Mazo V, Briones Z, Sanchis J; ARIS CAT Group: Prediction of postoperative pulmonary complications in a population-based surgical cohort. Anesthesiology 2010; 113:1338-50.
14. Blum JM, Maile M, Park PK, Morris M, Jewell E, Dechert R, Rosenberg AL: A description of intraoperative ventilator management in patients with acute lung injury and the use of lung protective ventilation strategies. Anesthesiology 2011; 115:75-82.
15. Ando K, Doi T, Moody SY, Ohkuni Y, Sato S, Kaneko N: The effect of comorbidity on the prognosis of acute lung injury and acute respiratory distress syndrome. Intern Med 2012; 51:1835-40.
16. Gong MN, Thompson BT, Williams P, Pothier L, Boyce PD, Christiani DC: Clinical predictors of and mortality in acute respiratory distress syndrome: Potential role of red cell transfusion. Crit Care Med 2005; 33:1191-8.
17. Sakr Y, Vincent JL, Reinhart K, Groeneveld J, Michalopoulos A, Sprung CL, Artigas A, Ranieri VM; Sepsis Occurrence in Acutely Ill Patients Investigators: High tidal volume and positive fluid balance are associated with worse outcome in acute lung injury. Chest 2005; 128:3098-108.
18. Ware LB, Koyama T, Billheimer DD, Wu W, Bernard GR, Thompson BT, Brower RG, Standiford TJ, Martin TR, Matthay MA; NHL BI ARDS Clinical Trials Network: Prognostic and pathogenetic value of combining clinical and biochemical indices in patients with acute lung injury. Chest 2010; 137:288-96.
19. Gajic O, Dabbagh O, Park PK, Adesanya A, Chang SY, Hou P, Anderson H III, Hoth JJ, Mikkelsen ME, Gentile NT, Gong MN, Talmor D, Bajwa E, Watkins TR, Festic E, Yilmaz M, Iscimen R, Kaufman DA, Esper AM, Sadikot R, Douglas I, Sevransky J, Malinchoc M; U.S. Critical Illness and Injury Trials Group: Lung Injury Prevention Study Investigators (USCIITG -LIPS): Early identification of patients at risk of acute lung injury: Evaluation of lung injury prediction score in a multicenter cohort study. Am J Respir Crit Care Med 2011; 183:462-70.
20. Brueckmann B, Villa-Uribe JL, Bateman BT, Grosse-Sundrup M, Hess DR, Schlett CL, Eikermann M: Development and validation of a score for prediction of postoperative respiratory complications. Anesthesiology 2013; 118:1276-85.
21. Roca O, Gómez-Ollés S, Cruz MJ, Muñoz X, Griffiths MJ, Masclans JR: Mechanical ventilation induces changes in exhaled breath condensate of patients without lung injury. Respir Med 2010; 104:822-8.
22. Fernandez R, Gili G, Villagra A, Lopez-Aguilar J, Artigas A: Assessment of the inflammatory effect of low-dose oxygen in mechanically ventilated patients. Intensive Care Med 2013; 39:711-6.
23. Arcêncio L, Vento DA, Bassetto S, Evora PR, Rodrigues AJ: Exhaled nitrite/nitrate levels as a marker of respiratory complications after heart valve surgery. J Crit Care 2013; 28:533. e1-e7.
24. Moloney ED, Mumby SE, Gajdocsi R, Cranshaw JH, Kharitonov SA, Quinlan GJ, Griffiths MJ: Exhaled breath condensate detects markers of pulmonary inflammation after cardiothoracic surgery. Am J Respir Crit Care Med 2004; 169:64-9.
25. Bastin AJ, Sato H, Davidson SJ, Quinlan GJ, Griffiths MJ: Biomarkers of lung injury after one-lung ventilation for lung resection. Respirology 2011; 16:138-45.
26. Gessner C, Hammerschmidt S, Kuhn H, Hoheisel G, Gillissen A, Sack U, Wirtz H: Breath condensate nitrite correlates with hyperinflation in chronic obstructive pulmonary disease. Respir Med 2007; 101:2271-8.
27. Sittipunt C, Steinberg KP, Ruzinski JT, Myles C, Zhu S, Goodman RB, Hudson LD, Matalon S, Martin TR: Nitric oxide and nitrotyrosine in the lungs of patients with acute respiratory distress syndrome. Am J Respir Crit Care Med 2001; 163:503-10.
28. Ranieri VM, Suter PM, Tortorella C, De Tullio R, Dayer JM, Brienza A, Bruno F, Slutsky AS: Effect of mechanical ventilation on inflammatory mediators in patients with acute respiratory distress syndrome: A randomized controlled trial. JAMA 1999; 282:54-61.
29. Cypel M, Liu M, Rubacha M, Yeung JC, Hirayama S, Anraku M, Sato M, Medin J, Davidson BL, de Perrot M, Waddell TK, Slutsky AS, Keshavjee S: Functional repair of human donor lungs by IL -10 gene therapy. Sci Transl Med 2009; 1:4-9.
30. Barker GF, Manzo ND, Cotich KL, Shone RK, Waxman AB: DNA damage induced by hyperoxia: Quantitation and correlation with lung injury. Am J Respir Cell Mol Biol 2006; 35:277-88.
31. Waxman AB, Einarsson O, Seres T, Knickelbein RG, Warshaw JB, Johnston R, Homer RJ, Elias JA: Targeted lung expression of interleukin-11 enhances murine tolerance of 100% oxygen and diminishes hyperoxia-induced DNA fragmentation. J Clin Invest 1998; 101:1970-82.
32. Kaynar AM, Houghton AM, Lum EH, Pitt BR, Shapiro SD: Neutrophil elastase is needed for neutrophil emigration into lungs in ventilator-induced lung injury. Am J Respir Cell Mol Biol 2008; 39:53-60.
33. Kodama T, Yukioka H, Kato T, Kato N, Hato F, Kitagawa S: Neutrophil elastase as a predicting factor for development of acute lung injury. Intern Med 2007; 46:699-704.
34. Broeckaert F, Clippe A, Knoops B, Hermans C, Bernard A: Clara cell secretory protein (CC16): Features as a peripheral lung biomarker. Ann N Y Acad Sci 2000; 923:68-77.
35. Lesur O, Langevin S, Berthiaume Y, Légaré M, Skrobik Y, Bellemare JF, Lévy B, Fortier Y, Lauzier F, Bravo G, Nickmilder M, Rousseau E, Bernard A; Critical Care Research Group of the Québec Respiratory Health Network: Outcome value of Clara cell protein in serum of patients with acute respiratory distress syndrome. Intensive Care Med 2006; 32:1167-74.
36. Sarafidis K, Stathopoulou T, Diamanti E, Soubasi V, Agakidis C, Balaska A, Drossou V: Clara cell secretory protein (CC16) as a peripheral blood biomarker of lung injury in ventilated preterm neonates. Eur J Pediatr 2008; 167:1297-303.
37. Determann RM, Wolthuis EK, Choi G, Bresser P, Bernard A, Lutter R, Schultz MJ: Lung epithelial injury markers are not influenced by use of lower tidal volumes during elective surgery in patients without preexisting lung injury. Am J Physiol Lung Cell Mol Physiol 2008; 294:L344-50.
38. De Conno E, Steurer MP, Wittlinger M, Zalunardo MP, Weder W, Schneiter D, Schimmer RC, Klaghofer R, Neff TA, Schmid ER, Spahn DR, Z'graggen BR, Urner M, Beck-Schimmer B: Anesthetic-induced improvement of the inflammatory response to one-lung ventilation. Anesthesiology 2009; 110:1316-26.
39. Schilling T, Kozian A, Kretzschmar M, Huth C, Welte T, Bühling F, Hedenstierna G, Hachenberg T: Effects of propofol and desflurane anaesthesia on the alveolar inflammatory response to one-lung ventilation. Br J Anaesth 2007; 99:368-75.
40. Chladkova J, Krcmova I, Chladek J, Cap P, Micuda S, Hanzalkova Y: Validation of nitrite and nitrate measurements in exhaled breath condensate. Respiration 2006; 73:173-9.
41. Horváth I, Hunt J, Barnes PJ, Alving K, Antczak A, Baraldi E, Becher G, van Beurden WJ, Corradi M, Dekhuijzen R, Dweik RA, Dwyer T, Effros R, Erzurum S, Gaston B, Gessner C, Greening A, Ho LP, Hohlfeld J, Jöbsis Q, Laskowski D, Loukides S, Marlin D, Montuschi P, Olin AC, Redington AE, Reinhold P, van Rensen EL, Rubinstein I, Silkoff P, Toren K, Vass G, Vogelberg C, Wirtz H; ATS/ERS Task Force on Exhaled Breath Condensate: Exhaled breath condensate: Methodological recommendations and unresolved questions. Eur Respir J 2005; 26:523-48.
42. Silkoff PE, Erzurum SC, Lundberg JO, George SC, Marczin N, Hunt JF, Effros R, Horvath I; American Thoracic Society; HOC Subcommittee of the Assembly on Allergy, Immunology, and Inflammation: ATS workshop proceedings: Exhaled nitric oxide and nitric oxide oxidative metabolism in exhaled breath condensate. Proc Am Thorac Soc 2006; 3:131-45.
43. Erzurum SC, Ghosh S, Janocha AJ, Xu W, Bauer S, Bryan NS, Tejero J, Hemann C, Hille R, Stuehr DJ, Feelisch M, Beall CM: Higher blood flow and circulating NO products offset highaltitude hypoxia among Tibetans. Proc Natl Acad Sci U S A 2007; 104:17593-8.
44. Driscoll KE: TNFα and MIP-2: Role in particle-induced inflammation and regulation by oxidative stress. Toxicol Lett 2000; 112-113:177-83.
45. Gaston B, Drazen JM, Loscalzo J, Stamler JS: The biology of nitrogen oxides in the airways. Am J Respir Crit Care Med 1994; 149(2 Pt 1):538-51.
46. Vaporidi K, Francis RC, Bloch KD, Zapol WM: Nitric oxide synthase 3 contributes to ventilator-induced lung injury. Am J Physiol Lung Cell Mol Physiol 2010; 299:L150-9.
47. Davidovich N, DiPaolo BC, Lawrence GG, Chhour P, Yehya N, Margulies SS : Cyclic stretch-induced oxidative stress increases pulmonary alveolar epithelial permeability. Am J Respir Cell Mol Biol 2013; 49:156-64.
48. Frank JA, Wray CM, McAuley DF, Schwendener R, Matthay MA: Alveolar macrophages contribute to alveolar barrier dysfunction in ventilator-induced lung injury. Am J Physiol Lung Cell Mol Physiol 2006; 291:L1191-8.
49. Ho LP, Innes JA, Greening AP: Nitrite levels in breath condensate of patients with cystic fibrosis is elevated in contrast to exhaled nitric oxide. Thorax 1998; 53:680-4.
50. Carvalho AR, Ichinose F, Schettino IA, Hess D, Rojas J, Giannella-Neto A, Agnihotri A, Walker J, MacGillivray TE, Vidal Melo MF: Tidal lung recruitment and exhaled nitric oxide during coronary artery bypass grafting in patients with and without chronic obstructive pulmonary disease. Lung 2011; 189:499-509.
51. Weitzberg E, Hezel M, Lundberg JO: Nitrate-nitrite-nitric oxide pathway: Implications for anesthesiology and intensive care. Anesthesiology 2010; 113:1460-75.
52. Zhao XJ, Wang L, Shiva S, Tejero J, Wang J, Frizzell S, Gladwin MT: Mechanisms for cellular NO oxidation and nitrite formation in lung epithelial cells. Free Radic Biol Med 2013; 61C:428-37.
53. Lundberg JO, Weitzberg E, Gladwin MT: The nitrate-nitritenitric oxide pathway in physiology and therapeutics. Nat Rev Drug Discov 2008; 7:156-67.
54. Araneda OF, Guevara AJ, Contreras C, Lagos N, Berral FJ: Exhaled breath condensate analysis after long distance races. Int J Sports Med 2012; 33:955-61.
55. Hammerschmidt S, Schiller J, Kuhn H, Meybaum M, Gessner C, Sandvoss T, Arnold K, Wirtz H: Influence of tidal volume on pulmonary NO release, tissue lipid peroxidation and surfactant phospholipids. Biochim Biophys Acta 2003; 1639:17-26.
56. Malinovschi A, Pizzimenti S, Sciascia S, Heffler E, Badiu I, Rolla G: Exhaled breath condensate nitrates, but not nitrites or FENO, relate to asthma control. Respir Med 2011; 105:1007-13.
57. Rihák V, Zatloukal P, Chládková J, Zimulová A, Havlínová Z, Chládek J: Nitrite in exhaled breath condensate as a marker of nitrossative stress in the airways of patients with asthma, COPD, and idiopathic pulmonary fibrosis. J Clin Lab Anal 2010; 24:317-22.
58. Determann RM, Royakkers AA, Haitsma JJ, Zhang H, Slutsky AS, Ranieri VM, Schultz MJ: Plasma levels of surfactant protein D and KL-6 for evaluation of lung injury in critically ill mechanically ventilated patients. BMC Pulm Med 2010; 10:6.
59. Parsons PE, Eisner MD, Thompson BT, Matthay MA, Ancukiewicz M, Bernard GR, Wheeler AP: Lower tidal volume ventilation and plasma cytokine markers of inflammation in patients with acute lung injury. Crit Care Med 2005; 33:1-6; discussion 230-2.
60. Waragai A, Yamashita H, Hosoi K, Hoshina H, Noda E, Yan K, Kawano T: High-frequency oscillation (HFO) prevents activation of NF-kappaB found with conventional mechanical ventilation (CMV) in surfactant-depleted rabbit lung. Pediatr Pulmonol 2007; 42:440-5.
61. Wolthuis EK, Vlaar AP, Choi G, Roelofs JJ, Juffermans NP, Schultz MJ: Mechanical ventilation using non-injurious ventilation settings causes lung injury in the absence of preexisting lung injury in healthy mice. Crit Care 2009; 13:R1.
62. Choi G, Wolthuis EK, Bresser P, Levi M, van der Poll T, Dzoljic M, Vroom MB, Schultz MJ: Mechanical ventilation with lower tidal volumes and positive end-expiratory pressure prevents alveolar coagulation in patients without lung injury. Anesthesiology 2006; 105:689-95.
63. Chen HI, Hsieh NK, Kao SJ, Su CF: Protective effects of propofol on acute lung injury induced by oleic acid in conscious rats. Crit Care Med 2008; 36:1214-21.
64. Fujishima S, Morisaki H, Ishizaka A, Kotake Y, Miyaki M, Yoh K, Sekine K, Sasaki J, Tasaka S, Hasegawa N, Kawai Y, Takeda J, Aikawa N: Neutrophil elastase and systemic inflammatory response syndrome in the initiation and development of acute lung injury among critically ill patients. Biomed Pharmacother 2008; 62:333-8.
65. Gattinoni L, Protti A, Caironi P, Carlesso E: Ventilator-induced lung injury: The anatomical and physiological framework. Crit Care Med 2010; 38(10 suppl):S539-48.
66. Gattinoni L, Carlesso E, Brazzi L, Caironi P: Positive endexpiratory pressure. Curr Opin Crit Care 2010; 16:39-44.
67. Hadimioglu N, Ulugol H, Akbas H, Coskunfirat N, Ertug Z, Dinckan A: Combination of epidural anesthesia and general anesthesia attenuates stress response to renal transplantation surgery. Transplant Proc 2012; 44:2949-54.
68. Ahlers O, Nachtigall I, Lenze J, Goldmann A, Schulte E, Höhne C, Fritz G, Keh D: Intraoperative thoracic epidural anaesthesia attenuates stress-induced immuno suppression in patients undergoing major abdominal surgery. Br J Anaesth 2008; 101:781-7.
69. Martin F, Martinez V, Mazoit JX, Bouhassira D, Cherif K, Gentili ME, Piriou P, Chauvin M, Fletcher D: Antiinflammatory effect of peripheral nerve blocks after knee surgery: Clinical and biologic evaluation. Anesthesiology 2008; 109:484-90.
70. Høgevold HE, Lyberg T, Kähler H, Haug E, Reikerås O: Changes in plasma IL -1β, TNF-α and IL -6 after total hip replacement surgery in general or regional anaesthesia. Cytokine 2000; 12:1156-9.
71. Michel O, Murdoch R, Bernard A: Inhaled LPS induces blood release of Clara cell specific protein (CC16) in human beings. J Allergy Clin Immunol 2005; 115:1143-7.
72. Wutzler S, Lehnert T, Laurer H, Lehnert M, Becker M, Henrich D, Vogl T, Marzi I: Circulating levels of Clara cell protein 16 but not surfactant protein D identify and quantify lung damage in patients with multiple injuries. J Trauma 2011; 71:E31-6.
73. Lesur O, Hermans C, Chalifour JF, Picotte J, Lévy B, Bernard A, Lane D: Mechanical ventilation-induced pneumoprotein CC-16 vascular transfer in rats: Effect of KGF pretreatment. Am J Physiol Lung Cell Mol Physiol 2003; 284:L410-9.
74. Chiumello D, Carlesso E, Cadringher P, Caironi P, Valenza F, Polli F, Tallarini F, Cozzi P, Cressoni M, Colombo A, Marini JJ, Gattinoni L: Lung stress and strain during mechanical ventilation for acute respiratory distress syndrome. Am J Respir Crit Care Med 2008; 178:346-55.