Nitrite in exhaled breath condensate as a marker of nitrossative stress in the airways of patients with asthma, COPD, and idiopathic pulmonary fibrosis

Journal of Clinical Laboratory Analysis

Volumn 24, Issue 5, 2010, Pages 317-322

  Rihák, Vladimír ^a   Zatloukal, Petr ^b   Chládková, Jirina ^b   Zimulová, Alena ^a   Havlínová, Zuzana ^b   Chládek, Jaroslav ^b  

^a Bata Hospital   (Czech Republic)

^b CHARLES UNIVERSITY   (Czech Republic)

Author keywords

Breath condensate; Nitrate; Nitrite; Nitrossative stress; Pulmonary diseases

Indexed keywords

NITRITE;

ADULT; AGED; AIRWAY; ARTICLE; ASTHMA; CHRONIC OBSTRUCTIVE LUNG DISEASE; CONTROLLED STUDY; DISEASE EXACERBATION; DISEASE MARKER; DISEASE SEVERITY; EXPIRED AIR; FEMALE; FIBROSING ALVEOLITIS; FLUORESCENCE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; LUNG FUNCTION; MAJOR CLINICAL STUDY; MALE; NITROSSATIVE STRESS; STRESS;

ADULT; AGED; ASTHMA; BIOLOGICAL MARKERS; BREATH TESTS; CASE-CONTROL STUDIES; EXHALATION; FEMALE; HUMANS; IDIOPATHIC PULMONARY FIBROSIS; MALE; MIDDLE AGED; NITRITES; PULMONARY DISEASE, CHRONIC OBSTRUCTIVE; RESPIRATORY SYSTEM; STRESS, PHYSIOLOGICAL;

EID: 77957288187     PISSN: 08878013     EISSN: 10982825     Source Type: Journal    
DOI: 10.1002/jcla.20408     Document Type: Article

References (43)

1. Gustafsson LE, Leone AM, Persson MG, Wiklund NP, Moncada S. Endogenous nitric oxide is present in the exhaled air of rabbits, guinea pigs and humans. Biochem Biophys Res Commun 1991;181: 852-857.
2. Ojoo JC, Mulrennan SA, Kastelik JA, Morice AH, Redington AE. Exhaled breath condensate pH and exhaled nitric oxide in allergic astma and in cystic fibrosis. Thorax 2005;60:22-26. (Pubitemid 40101013)
3. Kharitonov SA, Yates D, Robbins RA, Logan-Sinclair R, Shinebourne EA, Barnes PJ. Increased nitric oxid in exhaled air in asthmatic pacients. Lancet 1994;343:133-135.
4. Persson MG, Zetterström O, Agrenius V, Ihre E, Gustafsson LE. Single breath nitric oxide measurements in asthmatic patients and smokers. Lancet 1994;343:146-147.
5. Silkoff PE, Robbins RA, Gaston B, Lundberg JO, Townley RG. Endogenous nitric oxide in allergic airway disease. J Allergy Clin Immunol 2000;105:438-448. (Pubitemid 30169899)
6. Moncada S, Higgs. The L-arginine-nitric oxide pathway. N Engl J Med 1993;329:2002-2012.
7. Horváth I, Hunt J, Barnes PJ, et al. ATS/ERS task force on exhaled breath condensate exhaled breath condensate: methodological recommendations and unresolved questions. Eur Respir J 2005;26:523-548.
8. Global Strategy for Asthma Management and Prevention, Global Initiative for Asthma (GINA) 2007. Available from: http:// www.ginasthma.org
9. Global Initiative for Chronic Obstructive Lung Disease. Global strategy for the diagnosis, management, and prevention of chronic obstructive pulmonary disease 2007. Available from: www.goldcopd.com
10. American Thoracic Society/European Respiratory Society. International multidisciplinary consensus classification of the idiopathic interstitial pneumonias. Am J Respir Crit Care Med 2002;165:277-304.
11. Chladkova J, Krcmova I, Chladek J, Cap P, Micuda S, Hanzalkova Y. Validation of nitrite and nitrate measurements in exhaled breath condensate. Respiration 2006;73:173-179.
12. Misko TP, Schilling RJ, Salvemini D, Moore WM, Currie MG. A fluorometric assay for the measurement of nitrite in biological samples. Anal Biochem 1993;214:11-16.
13. Jackson AS, Sandrini A, Campbell C, Chow S, Thomas PS, Yates DH. Comparison of biomarkers in exhaled breath condensate and bronchoalveolar lavage. Am J Respir Crit Care Med 2007;175:222-227.
14. Balint B, Donnelly LE, Hanazawa T, Kharitonov SA, Barnes PJ. Increased nitric oxide metabolites in exhaled breath condensate after exposure to tobacco smoke. Thorax 2001;56:456-461. (Pubitemid 32521363)
15. Cruz MJ, Sánchez-Vidaurre S, Romero PV, Morell F, Muñoz X. Impact of age on pH, 8-isoprostane, and nitrogen oxides in exhaled breath condensate. Chest 2009;135:462-467.
16. Nightingale JA, Rogers DF, Barnes PJ. Effect of inhaled ozone on exhaled nitric oxide, pulmonary function, and induced sputum in normal and asthmatic subjects. Thorax 1999;54:1061-1069.
17. Liu J, Sandrini A, Thurston MC, Yates DH, Thomas PS. Nitric oxide and exhaled breath nitrite/nitrate in chronic obstructive pulmonary disease patients. Respiration 2007;74:617-623.
18. Corradi M, Pesci A, Casana R, et al. Nitrate in exhaled breath condensate of patients with different airway diseases. Nitric Oxide 2003;8:26-30. (Pubitemid 36266700)
19. Saleh D, Barnes PJ, Giaid A. Increased production of the potent oxidant peroxynitrite in the lungs of patients with idiopathic pulmonary fibrosis. Am J Respir Crit Care Med 1997;155:1763-1769.
20. Paredi P, Kharitonov SA, Loukides S, Pantelidis P, du Bois RM, Barnes PJ. Exhaled nitric oxide is increased in active fibrosing alveolitis. Chest 1999;115:1352-1356.
21. Montaldo C, Cannas E, Ledda M, Rosetti L, Congiu L, Atzori L. Bronchoalveolar glutathione and nitrite/nitrate in idiopathic pulmonary fibrosis and sarcoidosis. Sarcoidosis Vasc Diffuse Lung Dis 2002;19:54-58. (Pubitemid 34298495)
22. Behera D, Kaur S, Sathyanarayana G, Bhatnagar A, Majumdar S. Nitric oxide derivative in bronchoalveolar lavage fluid from patients with idiopathic pulmonary fibrosis. Indian J Chest Dis Allied Sci 2002;44:21-24.
23. Kanoh S, Kobayashi H, Motoyoshi K. Exhaled ethane: An in vivo biomarker of lipid peroxidation in interstitial lung diseases. Chest 2005;128:2387-2392.
24. Psathakis K, Mermigkis D, Papatheodorou G, et al. Exhaled markers of oxidative stress in idiopathic pulmonary fibrosis. Eur J Clin Invest 2006;36:362-367.
25. Bargagli E, Olivieri C, Bennett D, Prasse A, Muller-Quernheim J, Rottoli P. Oxidative stress in the pathogenesis of diffuse lung diseases: a review. Respir Med 2009;103:1245-1256.
26. Taylor DR, Pijnenburg MW, Smith AD, De Jongste JC. Exhaled nitric oxide measurements: Clinical application and interpretation. Thorax 2006;61:817-827.
27. Formanek W, Inci D, Lauener RP, Wildhaber JH, Frey U, Hall GL. Elevated nitrite in breath condensates of children with respiratory disease. Eur Respir J 2002;19:487-491. (Pubitemid 34256964)
28. Hunt J, Byrns RE, Ignarro LJ, Gaston B. Condensed expirate nitrite as a home marker for acute asthma. Lancet 1995;346:1235-1236.
29. Ueno T, Kataoka M, Hirano A, et al. Inflammatory markers in exhaled breath condensate from patients with asthma. Respirology 2008;13:654-663.
30. Ratnawati, Morton J, Henry RL, Thomas PS. Exhaled breath condensate nitrite/nitrate and pH in relation to pediatric asthma control and exhaled nitric oxide. Pediatr Pulmonol 2006;41:929-936.
31. Robroeks CM, van de Kant KD, Jöbsis Q, et al. Exhaled nitric oxide and biomarkers in exhaled breath condensate indicate the presence, severity and control of childhood asthma. Clin Exp Allergy 2007;37:1303-1311.
32. Kharitonov SA, Barnes PJ. Biomarkers of some pulmonary diseases in exhaled breath. Biomarkers 2002;7:1-32. (Pubitemid 34097607)
33. Delen FM, Sippel JM, Osborne ML, Law S, Thukkani N, Holden WE. Increased exhaled nitric oxide in chronic bronchitis: Comparison with asthma and COPD. Chest 2000;117:695-701.
34. IchinoseM, Sugiura H, Yamagata S, Koarai A, Shirato K. Increase in reactive nitrogen species production in chronic obstructive pulmonary disease airways. Am J Respir Crit Care Med 2000;162:701-706.
35. Rutgers SR, van der Mark TW, Coers W, et al. Markers of nitric oxide metabolism in sputum and exhaled air are not increased in chronic obstructive pulmonary disease. Thorax 1999;54:576-580.
36. Maziak W, Loukides S, Culpitt S, Sullivan P, Kharitonov SA, Barnes PJ. Exhaled nitric oxide in chronic obstructive pulmonary disease. Am J Respir Crit Care Med 1998;157:998-1002. (Pubitemid 28150721)
37. Paredi P, Ward S, Cramer D, Barnes PJ, Kharitonov SA. Normal bronchial blood flow in COPD is unaffected by inhaled corticosteroids and correlates with exhaled nitric oxide. Chest 2007;131:1075-1081.
38. Agustí AG, Villaverde JM, Togores B, Bosch M. Serial measurements of exhaled nitric oxide during exacerbations of chronic obstructive pulmonary disease. Eur Respir J 1999;14:523-528.
39. Borrill ZL, Roy K, Singh D. Exhaled breath condensate biomarkers in COPD. Eur Respir J 2008;32:472-486.
40. Corradi M, Montuschi P, Donnelly LE, Pesci A, Kharitonov SA, Barnes PJ. Increased nitrosothiols in exhaled breath condensate in inflammatory airway diseases. Am J Respir Crit Care Med 2001; 163:854-858. (Pubitemid 32275854)
41. 2, nitrite/nitrate and pH in exhaled breath condensate during and after acute COPD exacerbation (abstract). Am J Respir Crit Care Med 2005;171:A932.
42. Olin AC, Rosengren A, Thelle DS, Lissner L, Bake B, Torén K. Height, age, and atopy are associated with fraction of exhaled nitric oxide in a large adult general population sample. Chest 2006;130:1319-1325.
43. Sundy JS, Hauswirth DW, Mervin-Blake S, et al. Smoking is associated with an age-related decline in exhaled nitric oxide. Eur Respir J 2007;30:1074-1081.