Mechanical ventilation with lower tidal volumes and positive end-expiratory pressure prevents alveolar coagulation in patients without lung injury

Anesthesiology

Volumn 105, Issue 4, 2006, Pages 689-695

  Choi, Goda ^a,c   Wolthuis, Esther K ^a   Bresser, Paul ^a   Levi, Marcel ^a   Van Der Poll, Tom ^a   Dzoljic, Misa ^b   Vroom, Margreeth B ^b   Schultz, Marcus J ^b  

^a Center for Experimental and Molecular Medicine   (Netherlands)

^b ACADEMIC MEDICAL CENTER   (Netherlands)

^c UNIVERSITY OF AMSTERDAM   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVATED PROTEIN C; BLOOD CLOTTING FACTOR 7A; THROMBIN; THROMBIN ANTITHROMBIN COMPLEX; THROMBOMODULIN; THROMBOPLASTIN;

ACUTE LUNG INJURY; ADULT; ANESTHESIA INDUCTION; ARTICLE; ARTIFICIAL VENTILATION; BLOOD SAMPLING; BODY WEIGHT; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DISEASE MARKER; ELECTIVE SURGERY; FEMALE; FIBRIN DEPOSITION; FIBRINOLYSIS; HUMAN; LUNG LAVAGE; LUNG VENTILATION; MAJOR CLINICAL STUDY; MALE; OPERATION DURATION; POSITIVE END EXPIRATORY PRESSURE; PRIORITY JOURNAL; RANDOMIZATION; RANDOMIZED CONTROLLED TRIAL; SURGICAL PATIENT; TIDAL VOLUME; VENTILATOR ASSOCIATED PNEUMONIA;

AGED; ANESTHESIA, GENERAL; ANTITHROMBINS; BLOOD COAGULATION DISORDERS; BRONCHOALVEOLAR LAVAGE FLUID; CLINICAL PROTOCOLS; FEMALE; FIBRINOLYSIS; HEMODYNAMIC PROCESSES; HEMOSTASIS; HUMANS; MALE; MIDDLE AGED; PLASMINOGEN ACTIVATORS; POSITIVE-PRESSURE RESPIRATION; PULMONARY ALVEOLI; PULMONARY CIRCULATION; RESPIRATION, ARTIFICIAL; SURGICAL PROCEDURES, OPERATIVE; THROMBIN; TIDAL VOLUME;

EID: 33749186344     PISSN: 00033022     EISSN: 15281175     Source Type: Journal    
DOI: 10.1097/00000542-200610000-00013     Document Type: Article

References (34)

1. Levi M, Schultz MJ, Rijneveld AW, van der Poll T: Bronchoalveolar coagulation and fibrinolysis in endotoxemia and pneumonia. Crit Care Med 2003; 31:S238-42
2. Abraham E: Coagulation abnormalities in acute lung injury and sepsis. Am J Respir Cell Mol Biol 2000; 22:401-4
3. Günther A, Mosavi P, Heinemann S, Ruppert C, Muth H, Markart P, Grimminger F, Walmrath D, Temmesfeld-Wollbruck B, Seeger W: Alveolar fibrin formation caused by enhanced procoagulant and depressed fibrinolytic capacities in severe pneumonia: Comparison with the acute respiratory distress syndrome. Am J Respir Crit Care Med 2000; 161:454-62
4. Rijneveld AW, Florquin S, Bresser P, Levi M, De Waard V, Lijnen R, Van Der Zee JS, Speelman P, Carmeliet P, van der Poll T: Plasminogen activator inhibitor type-1 deficiency does not influence the outcome of murine pneumococcal pneumonia. Blood 2003; 102:934-9
5. Schultz MJ, Millo J, Levi M, Hack CE, Weverling GJ, Garrard CS, van der Poll T: Local activation of coagulation and inhibition of fibrinolysis in the lung during ventilator-associated pneumonia. Thorax 2004; 59:130-5
6. Choi G, Schultz MJ, van Till JW, Bresser P, Van Der Zee JS, Boermeester MA, Levi M, van der Poll T: Disturbed alveolar fibrin turnover during pneumonia is restricted to the site of infection. Eur Respir J 2004; 24:786-9
7. Idell S, Koenig KB, Fair DS, Martin TR, McLarty J, Maunder RJ: Serial abnormalities of fibrin turnover in evolving adult respiratory distress syndrome. Am J Physiol 1991; 261:L240-8
8. Slutsky AS: Lung injury caused by mechanical ventilation. Chest 1999; 116:9S-15S
9. Pinhu L, Whitehead T, Evans T, Griffiths M: Ventilator-associated lung injury. Lancet 2003; 361:332-40
10. The Acute Respiratory Distress Syndrome Network: Ventilation with lower tidal volumes as compared with traditional tidal volumes for acute lung injury and the acute respiratory distress syndrome. N Engl J Med 2000; 342:1301-8
11. Ranieri VM, Suter PM, Tortorella C, De Tullio, R, Dayer JM, Brienza A, Bruno F, Slutsky AS: Effect of mechanical ventilation on inflammatory mediators in patients with acute respiratory distress syndrome: A randomized controlled trial. JAMA 1999; 282:54-61
12. Wrigge H, Uhlig U, Zinserling J, Behrends-Callsen E, Ottersbach G, Fischer M, Uhlig S, Putensen C: The effects of different ventilatory settings on pulmonary and systemic inflammatory responses during major surgery. Anesth Analg 2004; 98:775-81
13. Wrigge H, Uhlig U, Baumgarten G, Menzenbach J, Zinserling J, Ernst M, Dromann D, Welz A, Uhlig S, Putensen C: Mechanical ventilation strategies and inflammatory responses to cardiac surgery: A prospective randomized clinical trial. Intensive Care Med 2005; 31:1379-87
14. Maris NA, de Vos AF, Dessing MC, Spek CA, Lutter R, Jansen HM, Van Der Zee JS, Bresser P, van der PT: Antiinflammatory effects of salmeterol after inhalation of lipopolysaccharide by healthy volunteers. Am J Respir Crit Care Med 2005; 172:878-84
15. van der Poll T, Levi M, Nick JA, Abraham E: Activated protein C inhibits local coagulation after intrapulmonary delivery of endotoxin in humans. Am J Respir Crit Care Med 2005; 171:1125-8
16. Friederich PW, Levi M, Bauer KA, Vlasuk GP, Rote WE, Breederveld D, Keller T, Spataro M, Barzegar S, Buller HR: Ability of recombinant factor VIIa to generate thrombin during inhibition of tissue factor in human subjects. Circulation 2001; 103:2555-9
17. Liaw PC, Ferrell G, Esmon CT: A monoclonal antibody against activated protein C allows rapid detection of activated protein C in plasma and reveals a calcium ion dependent epitope involved in factor Va inactivation. J Thromb Haemost 2003; 1:662-70
18. Kopko PM, Marshall CS, MacKenzie MR, Holland PV, Popovsky MA: Transfusion-related acute lung injury: Report of a clinical look-back investigation. JAMA 2002; 287:1968-71
19. Ranieri VM, Giunta F, Suter PM, Slutsky AS: Mechanical ventilation as a mediator of multisystem organ failure in acute respiratory distress syndrome. JAMA 2000; 284:43-4
20. Spragg RG, Lewis JF, Walmrath HD, Johannigman J, Bellingan G, Laterre PF, Witte MC, Richards GA, Rippin G, Rathgeb F, Hafner D, Taut FJ, Seeger W: Effect of recombinant surfactant protein C-based surfactant on the acute respiratory distress syndrome. N Engl J Med 2004; 351:884-92
21. Chastre J, Fagon JY: Ventilator-associated pneumonia. Am J Respir Crit Care Med 2002; 165:867-903
22. Maris NA, de Vos AF, Bresser P, Van Der Zee JS, Meijers JC, Lijnen HR, Levi M, Jansen HM, van der Poll T: Activation of coagulation and inhibition of fibrinolysis in the lung after inhalation of lipopolysaccharide by healthy volunteers. Thromb Haemost 2005; 93:1036-40
23. Muth H, Maus U, Wygrecka M, Lohmeyer J, Grimminger F, Seeger W, Günther A: Pro- and antifibrinolytic properties of human pulmonary microvascular versus artery endothelial cells: Impact of endotoxin and tumor necrosis factor-alpha. Crit Care Med 2004; 32:217-26
24. Wygrecka M, Markart P, Ruppert C, Kuchenbuch T, Fink L, Bohle RM, Grimminger F, Seeger W, Günther A: Compartment- and cell-specific expression of coagulation and fibrinolysis factors in the murine lung undergoing inhalational versus intravenous endotoxin application. Thromb Haemost 2004; 92:529-40
25. Idell S: Coagulation, fibrinolysis, and fibrin deposition in acute lung injury. Crit Care Med 2003; 31:S213-20
26. Choi G, Schultz MJ, Levi M, van der Poll T, Millo JL, Garrard CS: Protein C in pneumonia. Thorax 2005; 60:705-6
27. Bernard GR, Vincent JL, Laterre PF, LaRosa SP, Dhainaut JF, Lopez-Rodriguez A, Steingrub JS, Garber GE, Helterbrand JD, Ely EW, Fisher CJ Jr: Efficacy and safety of recombinant human activated protein C for severe sepsis. N Engl J Med 2001; 344:699-709
28. Nick JA, Coldren CD, Geraci MW, Poch KR, Fouty BW, O'Brien J, Gruber M, Zarini S, Murphy RC, Kuhn K, Richter D, Kast KR, Abraham E: Recombinant human activated protein C reduces human endotoxin-induced pulmonary inflammation via inhibition of neutrophil chemotaxis. Blood 2004; 104:3878-85
29. Vincent JL, Angus DC, Artigas A, Kalil A, Basson BR, Jamal HH, Johnson G III, Bernard GR: Effects of drotrecogin alfa (activated) on organ dysfunction in the PROWESS trial. Crit Care Med 2003; 31:834-40
30. Laterre PF, Garber G, Levy H, Wunderink R, Kinasewitz GT, Sollet JP, Maki DG, Bates B, Yan SC, Dhainaut JF: Severe community-acquired pneumonia as a cause of severe sepsis: Data from the PROWESS study. Crit Care Med 2005; 33:952-61
31. Levi M, van der Poll T, Büller HR: Bidirectional relation between inflammation and coagulation. Circulation 2004; 109:2698-704
32. Laterre PF, Wittebole X, Dhainaut JF: Anticoagulant therapy in acute lung injury. Crit Care Med 2003; 31:S329-36
33. Gajic O, Dara SI, Mendez JL, Adesanya AO, Festic E, Caples SM, Rana R, St Sauver JL, Lymp JF, Afessa B, Hubmayr RD: Ventilator-associated lung injury in patients without acute lung injury at the onset of mechanical ventilation. Crit Care Med 2004; 32:1817-24
34. Gajic O, Frutos-Vivar F, Esteban A, Hubmayr RD, Anzueto A: Ventilator settings as a risk factor for acute respiratory distress syndrome in mechanically ventilated patients. Intensive Care Med 2005; 31:922-6