Morin, a dietary flavonoid, exhibits anti-fibrotic effect and induces apoptosis of activated hepatic stellate cells by suppressing canonical NF-κB signaling

Biochimie

Volumn 110, Issue , 2015, Pages 107-118

  Madankumar, Perumal ^a   Naveenkumar, Perumal ^a   Devaraj, Halagowder ^a   Niranjalidevaraj, Sivasithamparam ^a  

^a UNIVERSITY OF MADRAS   (India)

Author keywords

Apoptosis; Diethylnitrosamine; Hepatic stellate cells; NF B; SMA

Indexed keywords

ALPHA SMOOTH MUSCLE ACTIN; ANTIFIBROTIC AGENT; CASPASE 3; CASPASE 9; CYCLOOXYGENASE 2; CYSTATIN C; DIETHYLNITROSAMINE; I KAPPA B ALPHA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 6; MESSENGER RNA; MORIN; PHOSPHATIDYLSERINE; PROTEIN BAX; PROTEIN BCL 2; TRANSCRIPTION FACTOR RELA; TUMOR NECROSIS FACTOR ALPHA; FLAVONOID;

ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; CELL DEATH; CELL NUCLEUS; CELL STRUCTURE; CELLULAR DISTRIBUTION; CONTROLLED STUDY; DNA FRAGMENTATION; DOWN REGULATION; DRUG EFFICACY; ENZYME ACTIVATION; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; IN VITRO STUDY; IN VIVO STUDY; LIVER FIBROSIS; MALE; MITOSIS INHIBITION; NONHUMAN; OUTER MEMBRANE; PHOSPHOLIPID BILAYER; PROTEIN CLEAVAGE; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN INDUCTION; PROTEIN LOCALIZATION; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; STELLATE CELL; UPREGULATION; WESTERN BLOTTING; ANIMAL; CELL LINE; CYTOLOGY; DIET; DRUG EFFECTS; LIVER CIRRHOSIS; METABOLISM; PATHOLOGY; WISTAR RAT;

RATTUS;

ANIMALS; APOPTOSIS; CELL LINE; DIET; FLAVONOIDS; HEPATIC STELLATE CELLS; HUMANS; LIVER CIRRHOSIS; MALE; NF-KAPPA B; RATS; RATS, WISTAR; SIGNAL TRANSDUCTION;

EID: 84921692431     PISSN: 03009084     EISSN: 61831638     Source Type: Journal    
DOI: 10.1016/j.biochi.2015.01.002     Document Type: Article

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