A fulminant hepatic failure model in the rat involvement of interleukin-1β and tumor necrosis factor-α

Digestive Diseases and Sciences

Volumn 46, Issue 8, 2001, Pages 1700-1708

  Shito, Masaya ^a,b   Balis, Ulysses J ^a,b   Tompkins, Ronald G ^a,b   Yarmush, Martin L ^a,b   Toner, Mehmet ^a,b  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

^b SHRINERS HOSPITALS FOR CHILDREN   (United States)

Author keywords

Animal model; Bioartificial liver support systems; Cytokine; D galactosamine; Hepatocellular injury

Indexed keywords

CYTOKINE; GALACTOSAMINE; INTERLEUKIN 1BETA; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ARTIFICIAL LIVER; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; HISTOLOGY; LIVER BIOPSY; LIVER DISEASE; LIVER FAILURE; LIVER FUNCTION; MALE; NONHUMAN; PATHOPHYSIOLOGY; PRIORITY JOURNAL; RAT; SURVIVAL RATE;

ANIMALS; DISEASE MODELS, ANIMAL; GALACTOSAMINE; INTERLEUKIN-1; LIVER; LIVER FAILURE; MALE; RATS; RATS, SPRAGUE-DAWLEY; SURVIVAL RATE; TUMOR NECROSIS FACTOR-ALPHA;

EID: 0034904222     PISSN: 01632116     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1010653504568     Document Type: Article

References (33)

1. Orthotopic liver transplantation in fulminant and subfulminant hepatitis. The Paul Brousse experience
2. Clinical experience with a bioartificial liver in the treatment of severe liver failure. A phase I clinical trial
3. Artificial hepatic support systems
4. Animal models of fulminant hepatic failure
5. A model of fulminant hepatic failure in the rabbit
6. A dog model for acetaminophen-induced fulminant hepatic failure
7. An anesthetized model of lethal canine galactosamine fulminant hepatic failure
8. Fulminant hepatic failure in rats: Survival and effect on blood chemistry and liver regeneration
9. Galactosamine induced liver injury
10. Brain edema and the blood brain barrier in galactosamine-induced fulminant hepatic failure rats. An animal model for evaluation of liver support systems
11. Effect of alanine on D-galactosamine-induced acute liver failure in rats
12. Role of polymorphonuclear leukocytes in galactosamine hepatitis: Mechanism of adherence to hepatic endothelial cells
13. Modulation of hepatotoxicity by macrophages in the liver
14. Shock and tissue injury induced by recombinant human cachectin
15. Staphylococces epidermidis induces complement activation, tumor necrosis factor and interleukin-1, a shock-like state and tissue injury in rabbits without endotoxemia. Comparison to Escherichia coli
16. Interleukin-1 and nitric oxide protect against tumor necrosis factor alpha-induced liver injury through distinct pathways
17. Tumor necrosis factor-induced hepatic DNA fragmentation as an early marker of T cell-dependent liver injury in mice
18. Interleukin 1 receptor blockade reduces tumor necrosis factor production, tissue injury, and mortality after hepatic ischemia-reperfucion in the rat
19. Interleukin 10 reduces lethality and hepatic injury induced by lipopolysaccharide in galactosamine-sensitized mice
20. Biochemical, hematological and histological changes in a fulminant hepatic failure rat model for artificial liver assessment
21. An improved model of galactosamine-induced fulminant hepatic failure in the pig
22. D-Galactosamine hepatotoxicity is associated with endotoxin sensitivity and mediated by lymphoreticular cells in mice
23. Effects of putrescine on D-galactosamine-induced acute liver failure in rats
24. Reversal of experimental acute hepatic failure in the rat
25. Gel-entrapment bioartificial liver therapy in galactosamine hepatitis
26. Semipermeable hollow fiber membranes in hepatocyte bioreactors: A prerequisite for a successful bioartificial liver?
27. Galactosamine-induced fulminant hepatic failure
28. Regional cerebral edema and chloride space in galactosamine-induced liver failure in rats
29. Impaired liver regeneration in inducible nitric oxide synthase-deficient mice
30. D-galactosamine hepatitis. I. Hepatocellular injury and fatty liver following a single dose
31. Endothelial cell gene expression of a neutrophil chemotactic factor by TNF-α, LPS, and IL-1 beta
32. Migration of neutrophils across endothelial monolayers is stimulated by treatment of the monolayers with interleukin-1 or tumor necrosis factor-alpha
33. Endotoxin-induced cytokine gene expression and excretion in the liver