SKI-1/S1P inhibitor PF-429242 impairs the onset of HCV infection

Antiviral Research

Volumn 115, Issue , 2015, Pages 94-104

  Blanchet, Matthieu ^a   Sureau, Camille ^b   Guévin, Carl ^a   Seidah, Nabil G ^c   Labonté, Patrick ^a  

^a INRS INSTITUT ARMAND FRAPPIER   (Canada)

^b INSTITUT NATIONAL DE LA TRANSFUSION SANGUINE   (France)

^c CLIN RESEARCH INSTITUTE OF MONTREAL   (Canada)

Author keywords

HCV; LDLR; PF 429242; SKI 1 S1P; SREBP; Viral entry

Indexed keywords

ANTIVIRUS AGENT; PF 429242; SERINE PROTEINASE INHIBITOR; SUBTILISIN; UNCLASSIFIED DRUG; VIRUS RNA; LDLR PROTEIN, HUMAN; LOW DENSITY LIPOPROTEIN RECEPTOR; MEMBRANE PROTEIN; MEMBRANE-BOUND TRANSCRIPTION FACTOR PEPTIDASE, SITE 1; NPC1L1 PROTEIN, HUMAN; PCSK9 PROTEIN, HUMAN; PF-429242; PYRROLIDINE DERIVATIVE; SERINE PROTEINASE;

ANTIVIRAL ACTIVITY; ARTICLE; CONTROLLED STUDY; DRUG EFFICACY; ENZYME INHIBITION; GENE EXPRESSION; GENOTYPE; HEPATITIS C; HEPATITIS C VIRUS; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; ANTAGONISTS AND INHIBITORS; DRUG EFFECTS; GENE EXPRESSION REGULATION; GENETICS; GROWTH, DEVELOPMENT AND AGING; HEPACIVIRUS; HUMAN; METABOLISM; TUMOR CELL LINE; VIRION; VIRUS REPLICATION;

HEPATITIS C VIRUS;

ANTIVIRAL AGENTS; CELL LINE, TUMOR; GENE EXPRESSION REGULATION, VIRAL; GENOTYPE; HEPACIVIRUS; HEPATITIS C; HUMANS; MEMBRANE PROTEINS; PROPROTEIN CONVERTASES; PYRROLIDINES; RECEPTORS, LDL; SERINE ENDOPEPTIDASES; SUBTILISIN; VIRION; VIRUS REPLICATION;

EID: 84921671695     PISSN: 01663542     EISSN: 18729096     Source Type: Journal    
DOI: 10.1016/j.antiviral.2014.12.017     Document Type: Article

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