The role of scavenger receptor class B type I (SR-BI) in lipid trafficking: Defining the rules for lipid traders

International Journal of Biochemistry and Cell Biology

Volumn 36, Issue 1, 2004, Pages 39-77

  Rhainds, David ^a   Brissette, Louise ^a  

^a UNIVERSITÉ DU QUÉBEC À MONTRÉAL   (Canada)

Author keywords

CD36; Cholesteryl ester selective uptake; High density lipoprotein; Low density lipoprotein; Reverse cholesterol transport; SR BI

Indexed keywords

CHOLESTEROL ESTER; CORTICOTROPIN; DEXAMETHASONE; ESTROGEN; HIGH DENSITY LIPOPROTEIN; LIPID; LIPOPROTEIN RECEPTOR; LOW DENSITY LIPOPROTEIN; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR; POLYUNSATURATED FATTY ACID; PROTEIN KINASE C; SCAVENGER RECEPTOR; STEROID HORMONE; TRANSCRIPTION FACTOR;

ADRENAL CORTEX; ADRENAL GLAND; ATHEROSCLEROSIS; BINDING SITE; CELL MEMBRANE; CELLULAR DISTRIBUTION; CHO CELL; CHOLESTEROL TRANSPORT; DNA MODIFICATION; DRUG POTENCY; ENDOCYTOSIS; ENDOTHELIUM CELL; FATTY ACID SYNTHESIS; GENE CONTROL; GENE FUNCTION; GENE OVEREXPRESSION; GENE STRUCTURE; GENETIC TRANSCRIPTION; HORMONE SYNTHESIS; HUMAN; IMMUNOFLUORESCENCE; INTESTINE; LIPID TRANSPORT; LIVER; LIVER CELL; MACROPHAGE; NONHUMAN; OVARY; PROMOTER REGION; PROTEIN BINDING; PROTEIN EXPRESSION; REVIEW; STEROIDOGENESIS; TESTIS;

RODENTIA;

EID: 0242317267     PISSN: 13572725     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1357-2725(03)00173-0     Document Type: Review

References (252)

1. Acton S.L., Osgood D., Donoghue M., Corella D., Pocovi M., Cenarro A., Mozas P., Keilty J., Squazzo S., Woolf E.A., Ordovas J.M. Association of polymorphisms at the SR-BI gene locus with plasma lipid levels and body mass index in a white population. Arteriosclerosis, Thrombosis, and Vascular Biology. 19:1999;1734-1743.
2. Acton S.L., Rigotti A., Landschulz K.T., Xu S., Hobbs H.H., Krieger M. Identification of scavenger receptor SR-BI as a high density lipoprotein receptor. Science. 271:1996;518-520.
3. Acton S.L., Scherer P.E., Lodish H.F., Krieger M. Expression cloning of SR-BI, a CD36-related class B scavenger receptor. The Journal of Biological Chemistry. 269:1994;21003-21009.
4. Altmann S.W., Davis H.R. Jr., Yao X., Laverty M., Compton D.S., Zhu L.J., Crona J.H., Caplen M.A., Hoos L.M., Tetzloff G., Priestley T., Burnett D.A., Strader C.D., Graziano M.P. The identification of intestinal scavenger receptor class B, type I (SR-BI) by expression cloning and its role in cholesterol absorption. Biochimica et Biophysica Acta. 1580:2002;77-93.
5. Amar M.J., Dugi K.A., Haudenschild C.C., Shamburek R.D., Foger B., Chase M., Bensadoun A., Hoyt R.F. Jr., Brewer H.B. Jr., Santamarina-Fojo S. Hepatic lipase facilitates the selective uptake of cholesteryl esters from remnant lipoproteins in apoE-deficient mice. Journal of Lipid Research. 39:1998;2436-2442.
6. Arai T., Rinninger F., Varban L., Fairchild-Huntress V., Liang C.P., Chen W., Seo T., Deckelbaum R., Huszar D., Tall A.R. Decreased selective uptake of high density lipoprotein cholesteryl esters in apolipoprotein E knockout mice. Proceedings of the National Academy of Sciences of the United States of America. 96:1999;12050-12055.
7. Arai T., Wang N., Bezouevsky M., Welch C., Tall A.R. Decreased atherosclerosis in heterozygous low density lipoprotein receptor-deficient mice expressing the scavenger receptor BI transgene. The Journal of Biological Chemistry. 274:1999;2366-2371.
8. Auger A., Truong T., Rhainds D., Lapointe J., Letarte F., Brissette L. Low and high density lipoprotein metabolism in primary cultures of hepatic cells from normal and apolipoprotein E knockout mice. European Journal of Biochemistry. 268:2001;2322-2330.
9. Azhar S., Luo Y., Medicherla S., Reaven E. Upregulation of selective cholesteryl ester uptake pathway in mice with deletion of low-density lipoprotein receptor function. Journal of Cell Physiology. 180:1999;190-202.
10. Azhar S., Nomoto A., Leers-Sucheta S., Reaven E. Simultaneous induction of an HDL receptor protein (SR-BI) and the selective uptake of HDL-cholesteryl esters in a physiologically relevant steroidogenic cell model. Journal of Lipid Research. 39:1998;1616-1628.
11. Azhar S., Nomoto A., Reaven E. Hormonal regulation of microvillar channel formation. Journal of Lipid Research. 43:2002;861-871.
12. Azhar S., Reaven E. Scavenger receptor class BI and selective cholesteryl ester uptake: Partners in the regulation of steroidogenesis. Molecular and Cellular Endocrinology. 195:2002;1-26.
13. Babitt J., Trigatti B., Rigotti A., Smart E.J., Anderson R.G.W., Xu S., Krieger M. Murine SR-BI, a high density lipoprotein receptor that mediates selective lipid uptake, is N-glycosylated and fatty acylated and colocalizes with plasma membrane caveolae. The Journal of Biological Chemistry. 272:1997;13242-13249.
14. Baranova I., Vishnyakova T., Bocharov A., Chen Z., Remaley A.T., Stonik J., Eggerman T.L., Patterson A.P. Lipopolysaccharide down regulates both scavenger receptor B1 and ATP binding cassette transporter A1 in RAW cells. Infection and Immunity. 70:2002;2995-3003.
15. Bennett M.K., Ngo T.T., Athanikar J.N., Rosenfeld J.M., Osborne T.F. Co-stimulation of promoter for low density lipoprotein receptor gene by sterol regulatory element-binding protein and Sp1 is specifically disrupted by the Yin Yang protein. The Journal of Biological Chemistry. 274:1999;13025-13032.
16. Braun A., Trigatti B.L., Post M.J., Sato K., Simons M., Edelberg J.M., Rosenberg R.D., Schrenzel M., Krieger M. Loss of SR-BI expression leads to the early onset of occlusive atherosclerotic coronary artery disease, spontaneous myocardial infarctions, severe cardiac dysfunction, and premature death in apolipoprotein E-deficient mice. Circulation Research. 90:2002;270-276.
17. Brown M.S., Deuel T.F., Basu S.K., Goldstein J.L. Inhibition of the binding of low-density lipoprotein to its cell surface receptor in human fibroblasts by positively charged proteins. Journal of Supramolecular Structures. 8:1978;223-234.
18. Buechler C., Ritter M., Quoc C.D., Agildere A., Schmitz G. Lipopolysaccharide inhibits the expression of the scavenger receptor Cla-1 in human monocytes and macrophages. Biochemical and Biophysical Research Communications. 262:1999;251-254.
19. Bultel-Brienne S., Lestavel S., Pilon A., Laffont I., Tailleux A., Fruchart J.C., Siest G., Clavey V. Lipid free apolipoprotein E binds to the class B type scavenger receptor (SR-BI) and enhances cholesteryl ester uptake from lipoproteins. The Journal of Biological Chemistry. 277:2003;36092-36099.
20. Cai S.F., Kirby R.J., Howles P.N., Hui D.Y. Differentiation-dependent expression and localization of the class B type I scavenger receptor in intestine. Journal of Lipid Research. 42:2001;902-909.
21. Calvo D., Dopazo J., Vega M.A. The CD36, CLA-1 (CD36L1), and LIMPII (CD36L2) gene family: Cellular distribution, chromosomal location, and genetic evolution. Genomics. 25:1995;100-106.
22. Calvo D., Gomez-Coronado D., Lascuncion M.A., Vega M.A. CLA-1 is an 85-kDa plasma membrane glycoprotein that acts as a high-affinity receptor for both native (HDL, LDL, and VLDL) and modified (OxLDL and AcLDL) lipoproteins. Arteriosclerosis, Thrombosis, and Vascular Biology. 17:1997;2341-2349.
23. Calvo D., Gomez-Coronado D., Suarez Y., Lasuncion M.A., Vega M.A. Human CD36 is a high affinity receptor for the native lipoproteins HDL, LDL, and VLDL. Journal of Lipid Research. 39:1998;777-788.
24. Calvo D., Vega M.A. Identification, primary structure, and distribution of CLA-1, a novel member of the CD36/LIMPII gene family. The Journal of Biological Chemistry. 268:1993;18929-18935.
25. Cao G., Garcia C.K., Wyne K.L., Schultz R.A., Parker K.L., Hobbs H.H. Structure and localization of the human gene encoding SR-BI/CLA-1. Evidence for transcriptional control by steroidogenic factor 1. The Journal of Biological Chemistry. 272:1997;33068-33076.
26. Cao G., Zhao L., Stangl H., Hasegawa T., Richardson J.A., Parker K.L., Hobbs H.H. Developmental and hormonal regulation of murine scavenger receptor, class B, type 1. Molecular Endocrinology. 13:1999;1460-1473.
27. Charest M.C., Rhainds D., Falstrault L., Matzouranis T., Brissette L. Selective uptake of cholesteryl ester from low density lipoprotein is involved in HepG2 cell cholesterol homeostasis. European Journal of Biochemistry. 263:1999;402-409.
28. Charpentier D., Tremblay C., Rassart E., Rhainds D., Auger A., Milne R.W., Brissette L. Low- and high-density lipoprotein metabolism in HepG2 cells expressing various levels of apolipoprotein E. Biochemistry. 39:2000;16084-16091.
29. Chawla A., Boisvert W.A., Lee C.H., Laffitte B.A., Barak Y., Joseph S.B., Liao D., Nagy L., Edwards P.A., Curtiss L.K., Evans R.M., Tontonoz P. A PPAR gamma-LXR-ABCA1 pathway in macrophages is involved in cholesterol efflux and atherogenesis. Molecular Cell. 7:2001;161-171.
30. Chen W., Silver D.L., Smith J.D., Tall A.R. Scavenger receptor-BI inhibits ATP-binding cassette transporter 1-mediated cholesterol efflux in macrophages. The Journal of Biological Chemistry. 275:2000;30794-30800.
31. Cherradi N., Bideau M., Arnaudeau S., Demaurex N., James R.W., Azhar S., Capponi A.M. Angiotensin II promotes selective uptake of high density lipoprotein cholesterol esters in bovine adrenal glomerulosa and human adrenocortical carcinoma cells through induction of scavenger receptor class B type I. Endocrinology. 142:2001;4540-4549.
32. Chinetti G., Gbaguidi F.G., Griglio S., Mallat Z., Antonucci M., Poulain P., Chapman J., Fruchart J.C., Tedgui A., Najib-Fruchart J., Staels B. CLA-1/SR-BI is expressed in atherosclerotic lesion macrophages and regulated by activators of peroxisome proliferator-activated receptors. Circulation. 101:2000;2411-2417.
33. Connelly M.A., de la Llera-Moya M., Monzo P., Yancey P.G., Drazul D., Stoudt G., Fournier N., Klein S.M., Rothblat G.H., Williams D.L. Analysis of chimeric receptors shows that multiple distinct functional activities of scavenger receptor, class B, type I (SR-BI) are localized to the extracellular domain. Biochemistry. 40:2001;5249-5259.
34. Connelly M.A., Kellner-Weibel G., Rothblat G.H., Williams D.L. SR-BI-directed HDL-cholesteryl ester hydrolysis. Journal of Lipid Research. 44:2003;331-341.
35. Connelly M.A., Klein S.M., Azhar S., Abumrad N.A., Williams D.L. Comparison of class B scavenger receptors, CD36 and scavenger receptor BI (SR-BI), shows that both receptors mediate high density lipoprotein-cholesteryl ester selective uptake but SR-BI exhibits a unique enhancement of cholesteryl ester uptake. The Journal of Biological Chemistry. 274:1999;41-47.
36. Cristobal S., Ochoa B., Fresnedo O. Purification and properties of a cholesteryl ester hydrolase from rat liver microsomes. Journal of Lipid Research. 40:1999;715-725.
37. Daviet L., Malvoisin E., Wild T.F., McGregor J.L. Thrombospondin induces dimerization of membrane-bound, but not soluble CD36. Thrombosis and Haemostatis. 78:1997;897-901.
38. 2 promotes scavenger receptor class B type I interaction and accelerates HDL catabolism. Journal of Lipid Research. 41:2000;1849-1857.
39. de Beer M.C., Durbin D.M., Cai L., Jonas A., de Beer F.C., van der Westhuyzen D.R. Apolipoprotein A-I conformation markedly influences HDL interaction with scavenger receptor BI. Journal of Lipid Research. 42:2001;309-313.
40. de Beer M.C., Durbin D.M., Cai L., Mirocha N., Jonas A., Webb N.R., de Beer F.C., van der Westhuyzen D.R. Apolipoprotein A-II modulates the binding and selective lipid uptake of reconstituted high density lipoprotein by scavenger receptor BI. The Journal of Biological Chemistry. 276:2001;15832- 15839.
41. de la Llera-Moya M., Connelly M.A., Drazul D., Klein S.M., Favari E., Yancey P.G., Williams D.L., Rothblat G.H. Scavenger receptor class B type I affects cholesterol homeostasis by magnifying cholesterol flux between cells and HDL. Journal of Lipid Research. 42:2001;1969-1978.
42. de la Llera-Moya M., Rothblat G.H., Connelly M.A., Kellner-Weibel G., Sakr S.W., Phillips M.C., Williams D.L. Scavenger receptor BI (SR-BI) mediates free cholesterol flux independently of HDL tethering to the cell surface. Journal of Lipid Research. 40:1999;575-580.
43. DeLamatre J.G., Carter R.M., Hornick C.A. Evidence for extralysosomal hydrolysis of high-density lipoprotein cholesteryl esters in rat hepatoma cells (Fu5AH): A model for delivery of high-density lipoprotein cholesterol. Journal of Cell Physiology. 146:1991;18-24.
44. DeLamatre J.G., Carter R.M., Hornick C.A. Evidence that a neutral cholesteryl ester hydrolase is responsible for the extralysosomal hydrolysis of high-density lipoprotein cholesteryl ester in rat hepatoma cells (Fu5AH). Journal of Cell Physiology. 157:1993;164-168.
45. DeLamatre J.G., Sarphie T.G., Archibold R.C., Hornick C.A. Metabolism of apoE-free high density lipoproteins in rat hepatoma cells: Evidence for a retroendocytic pathway. Journal of Lipid Research. 31:1990;191-202.
46. de Villiers W.J.S., Smart E.J. Macrophage scavenger receptors and foam cell formation. Journal of Leukocyte Biology. 66:1999;740-746.
47. Dietschy J.M., Turley S.D. Control of cholesterol turnover in the mouse. The Journal of Biological Chemistry. 277:2002;3801-3804.
48. Dorahy D.J., Lincz L.F., Meldrum C.J., Burns G.F. Biochemical isolation of a membrane microdomain from resting platelets highly enriched in the plasma membrane glycoprotein CD36. The Biochemical Journal. 319:1996;67-72.
49. Duncan K.G., Bailey K.R., Kane J.P., Schwartz D.M. Human retinal pigment epithelial cells express scavenger receptors BI and BII. Biochemical and Biophysical Research Communications. 292:2002;1017-1022.
50. Eisenberg S. High density lipoprotein metabolism. Journal of Lipid Research. 25:1984;1017-1058.
51. Endemann G., Stanton L.W., Madden K.S., Bryant C.M., White R.T., Protter A.A. CD36 is a receptor for oxidized low density lipoprotein. The Journal of Biological Chemistry. 268:1993;11811-11816.
52. Fidge N.M. High density lipoprotein receptors, binding proteins, and ligands. Journal of Lipid Research. 40:1999;187-201.
53. Fluiter K., Sattler W., de Beer M.C., Connell P.M., van der Westhuyzen D.R., van Berkel T.J.C. Scavenger receptor BI mediates the selective uptake of oxidized cholesterol esters by rat liver. The Journal of Biological Chemistry. 274:1999;8893-8899.
54. Fluiter K., van Berkel T.J.C. Scavenger receptor B1 (SR-B1) substrates inhibit the selective uptake of high-density-lipoprotein cholesteryl esters by rat parenchymal cells. The Biochemical Journal. 326:1997;515-519.
55. Fluiter K., van der Westhuijzen D.R., van Berkel T.J.C. In vivo regulation of scavenger receptor BI and the selective uptake of high density lipoprotein cholesteryl esters in rat liver parenchymal and Kupffer cells. The Journal of Biological Chemistry. 273:1998;8434-8438.
56. Franc N.C., Dimarcq J.L., Lagueux M., Hoffmann J., Ezelowitz R.A. Croquemort, a novel Drosophila hemocyte/macrophage receptor that recognizes apoptotic cells. Immunity. 4:1996;431-443.
57. Francis G.A., Tsujita M., Terry T.L. Apolipoprotein AI efficiently binds to and mediates cholesterol and phospholipid efflux from human but not rat aortic smooth muscle cells. Biochemistry. 38:1999;16315-16322.
58. Frank P.G., Marcel Y.L., Connelly M.A., Lublin D.M., Franklin V., Williams D.L., Lisanti M.P. Stabilization of caveolin-1 by cellular cholesterol and scavenger receptor class B type I. Biochemistry. 41:2002;11931-11940.
59. Frank P.G., Pedraza A., Cohen D.E., Lisanti M.P. Adenovirus-mediated expression of caveolin-1 in mouse liver increases plasma high-density lipoprotein levels. Biochemistry. 40:2001;10892-10900.
60. Fruchart J.C., Ailhaud G., Bard J.M. Heterogeneity of high density lipoprotein particles. Circulation (Supplement). 87:1993;III22-III27.
61. Fuchs M., Ivandic B., Muller O., Schalla C., Scheibner J., Bartsch P., Stange E.F. Biliary cholesterol hypersecretion in gallstone-susceptible mice is associated with hepatic up-regulation of the high-density lipoprotein receptor SR-BI. Hepatology. 33:2001;1451-1459.
62. Fujimoto T., Kogo H., Nomura R., Une T. Isoforms of caveolin-1 and caveolar structure. Journal of Cell Science. 113:2000;3509-3517.
63. Gälman C., Angelin B., Rudling M. Prolonged stimulation of the adrenals by corticotropin suppresses hepatic low-density lipoprotein and high-density lipoprotein receptors and increases plasma cholesterol. Endocrinology. 143:2002;1809-1816.
64. Garcia A., Barbaras R., Collet X., Bogyo A., Chap H., Perret B. High-density lipoprotein 3 receptor-dependent endocytosis pathway in a human hepatoma cell line (HepG2). Biochemistry. 35:1996;13064-13071.
65. Garver W.S., Erickson R.P., Wilson J.M., Colton T.L., Hossain G.S., Kozloski M.A., Heidenreich R.A. Altered expression of caveolin-1 and increased cholesterol in detergent insoluble membrane fractions from liver in mice with Niemann-Pick disease type C. Biochimica et Biophysica Acta. 1361:1997;272-280.
66. Gilotte-Taylor K., Boullier A., Witztum J.L., Steinberg D., Quehenberger O. Scavenger receptor class B type I as a receptor for oxidized low density lipoprotein. Journal of Lipid Research. 42:2001;1474-1482.
67. Goldstein J.L., Brown M.S., Anderson R.G., Russell D.W., Schneider W.J. Receptor-mediated endocytosis: Concepts emerging from the LDL receptor system. Annual Review of Cell Biology. 1:1985;1-39.
68. Goti D., Hrzenjak A., Levak-Frank S., Frank S., van der Westhuyzen D.R., Malle E., Sattler W. Scavenger receptor class B, type I is expressed in porcine brain capillary endothelial cells and contributes to selective uptake of HDL-associated Vitamin E. Journal of Neurochemistry. 76:2001;498-508.
69. Graf G.A., Connell P.M., van der Westhuyzen D.R., Smart E.J. The class B, type I scavenger receptor promotes the selective uptake of high density lipoprotein cholesterol ethers into caveolae. The Journal of Biological Chemistry. 274:1999;12043-12048.
70. Graf G.A., Roswell K.L., Smart E.J. 17Beta-estradiol promotes the up-regulation of SR-BII in HepG2 cells and in rat livers. Journal of Lipid Research. 42:2001;1444-1449.
71. Greene D.J., Skeggs J.W., Morton R.E. Elevated triglyceride content diminishes the capacity of high density lipoprotein to deliver cholesteryl esters via the scavenger receptor class B type I (SR-BI). The Journal of Biological Chemistry. 276:2001;4804-4811.
72. 125I -low density lipoprotein of altered composition from skin fibroblasts in culture The Journal of Biological Chemistry. 259:1984;1703-1713.
73. 3H ]-cholesterol efflux to high and low density lipoproteins is dependent on lipoprotein binding to the receptor The Journal of Biological Chemistry. 275:2000;29993-30001.
74. Gu X., Lawrence R., Krieger M. Dissociation of the high density lipoprotein and low density lipoprotein binding activities of murine scavenger receptor class B type I (mSR-BI) using retrovirus library-based activity dissection. The Journal of Biological Chemistry. 275:2000;9120-9130.
75. Gu X., Trigatti B.L., Xu S., Acton S.L., Babitt J., Krieger M. The efficient cellular uptake of high density lipoprotein lipids via scavenger receptor class B type I requires not only receptor-mediated surface binding but also receptor-specific lipid transfer mediated by its extracellular domain. The Journal of Biological Chemistry. 273:1998;26338-26348.
76. Gwynne J.T., Mahaffee D.D. Rat adrenal uptake and metabolism of high density lipoprotein cholesteryl ester. The Journal of Biological Chemistry. 264:1989;8141-8150.
77. Han J., Nicholson A.C., Zhou X., Feng J., Gotto A.M. Jr., Hajjar D.P. Oxidized low density lipoprotein decreases macrophage expression of scavenger receptor B-I. The Journal of Biological Chemistry. 276:2001;6567-6572.
78. Hatzopoulos A.K., Rigotti A., Rosenberg R.D., Krieger M. Temporal and spatial pattern of expression of the HDL receptor SR-BI during murine embryogenesis. Journal of Lipid Research. 39:1998;495-508.
79. Hauser H., Dyer J.H., Nandy A., Vega M.A., Werder M., Bieliauskaite E., Weber F.E., Compassi S., Gemperli A., Boffelli D., Wehrli E., Schulthess G., Phillips M.C. Identification of a receptor mediating absorption of dietary cholesterol in the intestine. Biochemistry. 37:1998;17843-17850.
80. Heeren J., Grewal T., Jäckle S., Beisiegel U. Recycling of apolipoprotein E and lipoprotein lipase through endosomal compartments in vivo. The Journal of Biological Chemistry. 276:2001;42333-42338.
81. Hevonoja T., Pentikäinen M.O., Hyvönen M.T., Kovanen P.T., Ala-Torpela M. Structure of low density lipoprotein (LDL) particles: Basis for understanding molecular changes in modified LDL. Biochimica et Biophysica Acta. 1488:2000;189-210.
82. Hirano K., Yamashita S., Nakagawa Y., Ohya T., Matsuura F., Tsukamoto K., Okamoto Y., Matsuyama A., Matsumoto K., Miyagawa J., Matsuzawa Y. Expression of human scavenger receptor class B type I in cultured human monocyte-derived macrophages and atherosclerotic lesions. Circulation Research. 85:1999;108-116.
83. Holm T.M., Braun A., Trigatti B.L., Brugnara C., Sakamoto M., Krieger M., Andrews N.C. Failure of red blood cell maturation in mice with defects in the high-density lipoprotein receptor SR-BI. Blood. 99:2002;1817-1824.
84. Hornick C.A., Hui D.Y., DeLamatre J.G. A role for retrosomes in intracellular cholesterol transport from endosomes to the plasma membrane. American Journal of Physiology. 273:1997;C1075-C1081.
85. Hornick C.A., Thouron C., DeLamatre J.G., Huang J. Triacylglycerol hydrolysis in isolated hepatic endosomes. The Journal of Biological Chemistry. 267:1992;3396-3401.
86. Horton J.D., Goldstein J.L., Brown M.S. SREBPs: Activators of the complete program of cholesterol and fatty acid synthesis in the liver. Journal of Clinical Investigation. 109:2002;1125-1131.
87. Hullinger T.G., Panek R.L., Xu X., Karathanasis S.K. p21-activated kinase-1 (PAK1) inhibition of the human scavenger receptor class B, type I promoter in macrophages is independent of PAK1 kinase activity, but requires the GTPase-binding domain. The Journal of Biological Chemistry. 276:2001;46807-46814.
88. Husemann J., Loike J.D., Anankov R., Febbraio M., Silverstein S.C. Scavenger receptors in neurobiology and neuropathology: Their role on microglia and other cells of the nervous system. Glia. 40:2002;195-205.
89. Husemann J., Loike J.D., Kodama T., Silverstein S.C. Scavenger receptor class B type I (SR-BI) mediates adhesion of neonatal murine microglia to fibrillar beta-amyloid. Journal of Neuroimmunology. 114:2001;142-150.
90. Husemann J., Silverstein S.C. Expression of scavenger receptor class B, type I, by astrocytes and vascular smooth muscle cells in normal adult mouse and human brain and in Alzheimer's disease brain. American Journal of Pathology. 158:2001;825-832.
91. Huszar D., Varban M.L., Rinninger F., Feeley R., Arai T., Fairchild-Huntress V., Donovan M.J., Tall A.R. Increased LDL cholesterol and atherosclerosis in LDL receptor-deficient mice with attenuated expression of scavenger receptor B1. Arteriosclerosis, Thrombosis, and Vascular Biology. 20:2000;1068-1073.
92. Iadonato S.P., Bu G., Maksymovitch E.A., Schwartz A.L. Interaction of a 39 kDa protein with the low-density-lipoprotein-receptor-related protein (LRP) on rat hepatoma cells. The Biochemical Journal. 296:1993;867-875.
93. Ikemoto M., Arai H., Feng D., Tanaka K., Aoki J., Dohmae N., Takio K., Adachi H., Tsujimoto M., Inoue K. Identification of a PDZ-domain-containing protein that interacts with the scavenger receptor class B type I. Proceedings of the National Academy of Sciences of the United States of America. 97:2000;6538-6543.
94. Imachi H., Murao K., Hiramine C., Sayo Y., Sato M., Hosokawa H., Ishida T., Kodama T., Quehenberger O., Steinberg D., Takahara J. Human scavenger receptor B1 is involved in recognition of apoptotic thymocytes by thymic nurse cells. Laboratory Investigation. 80:2000;263-270.
95. Izem L., Rassart E., Kamate L., Falstrault L., Rhainds D., Brissette L. Effect of reduced low-density lipoprotein receptor level on HepG2 cell cholesterol metabolism. The Biochemical Journal. 329:1998;81-89.
96. Jaeckle S., Rinninger F., Lorenzen T., Greten H., Windler E. Dissection of compartments in rat hepatocytes involved in the intracellular trafficking of high-density lipoprotein particles or their selectively internalized cholesteryl esters. Hepatology. 17:1993;455-465.
97. Ji Y., Jian B., Wang N., Sun Y., de la Llera-Moya M., Phillips M.C., Rothblat G.H., Swaney J.B., Tall A.R. Scavenger receptor BI promotes high density lipoprotein-mediated cellular cholesterol efflux. The Journal of Biological Chemistry. 272:1997;20982-20985.
98. Ji Y., Wang N., Ramakrishnan R., Sehayek E., Huszar D., Breslow J.L., Tall A.R. Hepatic scavenger receptor BI promotes rapid clearance of high density lipoprotein free cholesterol and its transport into bile. The Journal of Biological Chemistry. 274:1999;33398-33402.
99. Jian B., de la Llera-Moya M., Ji Y., Wang N., Phillips M.C., Swaney J.B., Tall A.R., Rothblat G.H. Scavenger receptor class B, type I as a mediator of cellular cholesterol efflux to lipoproteins and phospholipid acceptors. The Journal of Biological Chemistry. 273:1998;5599-5606.
100. Johnson M.S., Svensson P.A., Boren J., Billig H., Carlsson L.M., Carlsson B. Expression of scavenger receptor class B type I in gallbladder columnar epithelium. Journal of Gastroenterology and Hepatology. 17:2002;713-720.
101. Johnson M.S., Svensson P.A., Helou K., Billig H., Levan G., Carlsson L.M., Carlsson B. Characterization and chromosomal localization of rat scavenger receptor class B type I, a high density lipoprotein receptor with a putative leucine zipper domain and peroxisomal targeting sequence. Endocrinology. 139:1998;72-80.
102. Johnson A.C., Yabu J.M., Hanson S., Shah V.O., Zager R.A. Experimental glomerulopathy alters renal cortical cholesterol, SR-B1, ABCA1, and HMG CoA reductase expression. American Journal of Pathology. 162:2003;283-291.
103. Kambouris A.M., Roach P.D., Calvert G.D., Nestel P.J. Retroendocytosis of high density lipoproteins by the human hepatoma cell line, HepG2. Arteriosclerosis. 10:1990;582-590.
104. Kawasaki Y., Nakagawa A., Nagaosa K., Shiratsuchi A., Nakanishi Y. Phosphatidylserine binding of class B scavenger receptor type I, a phagocytosis receptor of testicular Sertoli cells. The Journal of Biological Chemistry. 277:2002;27559-27566.
105. Kellner-Weibel G., de la Llera-Moya M., Connelly M.A., Stoudt G., Christian A.E., Haynes M.P., Williams D.L., Rothblat G.H. Expression of scavenger receptor BI in COS-7 cells alters cholesterol content and distribution. Biochemistry. 39:2000;221-229.
106. Khovidhunkit W., Moser A.H., Shigenaga J.K., Grunfeld C., Feingold K.R. Regulation of scavenger receptor class B type I in hamster liver and Hep3B cells by endotoxin and cytokines. Journal of Lipid Research. 42:2001;1636-1644.
107. Kim J.B., Spotts G.D., Halvorsen Y.D., Shih H.M., Ellenberger T., Towle H.C., Spiegelman B.M. Dual DNA binding specificity of ADD1/SREBP1 controlled by a single amino acid in the basic helix-loop-helix domain. Molecular and Cellular Biology. 15:1995;2582-2588.
108. Knecht T.P., Pittman R.C. A plasma membrane pool of cholesteryl esters that may mediate the selective uptake of cholesteryl esters form high-density lipoproteins. Biochimica et Biophysica Acta. 1002:1989;365-375.
109. Kolleck I., Schlame M., Fechner H., Looman A.C., Wissel H., Rustow B. HDL is the major source of Vitamin E for type II pneumocytes. Free Radical Biology and Medicine. 27:1999;882-890.
110. Kovanen P.T., Brown M.S., Goldstein J.L. Increased binding of low density lipoprotein to liver membranes of rats treated with 17α-ethinyl estradiol. The Journal of Biological Chemistry. 254:1979;11367-11373.
111. Kozarsky K.F., Donahee M.H., Glick J.M., Krieger M., Rader D.J. Gene transfer and hepatic overexpression of the HDL receptor SR-BI reduces atherosclerosis in the cholesterol-fed LDL receptor-deficient mouse. Arteriosclerosis, Thrombosis, and Vascular Biology. 20:2000;721-727.
112. Kozarsky K., Donahee M.H., Rigotti A., Iqbal S.N., Edelman E.R., Krieger M. Overexpression of the HDL receptor SR-BI alters plasma HDL and bile cholesterol levels. Nature. 387:1997;414-417.
113. Kraemer F.B., Shen W.J., Natu V., Patel S., Osuga J., Ishibashi S., Azhar S. Adrenal neutral cholesteryl ester hydrolase: Identification, subcellular distribution, and sex differences. Endocrinology. 143:2002;801-806.
114. Krieger M. Charting the fate of the "good cholesterol": Identification and characterization of the high-density lipoprotein receptor SR-BI. Annual Review of Biochemistry. 68:1999;523-558.
115. Krieger M., Herz J. Structures and functions of multiligand lipoprotein receptors: Macrophage scavenger receptors and LDL receptor-related protein (LRP). Annual Review of Biochemistry. 63:1994;601-637.
116. Lagrost L., Dengremont C., Athias A., de Geitere C., Fruchart J.C., Lallemant C., Gambert P., Castro G. Modulation of cholesterol efflux from Fu5AH hepatoma cells by the apolipoprotein content of high density lipoprotein particles. Particles containing various proportions of apolipoproteins A-I and A-II. The Journal of Biological Chemistry. 270:1995;13004-13009.
117. Lambert G., Amar M.J.A., Guo G., Brewer H.B. Jr., Gonzalez F.J. The farnesoid X-receptor is an essential regulator of cholesterol homeostasis. The Journal of Biological Chemistry. 278:2003;2563-2570.
118. Lambert G., Amar M.J., Martin P., Fruchart-Najib J., Foger B., Shamburek R.D., Brewer H.B. Jr., Santamarina-Fojo S. Hepatic lipase deficiency decreases the selective uptake of HDL-cholesteryl esters in vivo. Journal of Lipid Research. 41:2000;667-672.
119. Lambert G., Chase M.B., Dugi K., Bensadoun A., Brewer H.B. Jr., Santamarina-Fojo S. Hepatic lipase promotes the selective uptake of high density lipoprotein-cholesteryl esters via the scavenger receptor BI. Journal of Lipid Research. 40:1999;1294-1303.
120. Landschulz K.T., Pathak R.K., Rigotti A., Krieger M., Hobbs H.H. Regulation of scavenger receptor, class B, type I, a high density lipoprotein receptor, in liver and steroidogenic tissues of the rat. Journal of Clinical Investigation. 98:1996;984-995.
121. Langer C., Gansz B., Goepfert C., Engel T., Uehara Y., von Dehn G., Jansen H., Assmann G., von Eckardstein A. Testosterone up-regulates scavenger receptor BI and stimulates cholesterol efflux from macrophages. Biochemical and Biophysical Research Communications. 296:2002;1051-1057.
122. Li F., Huang Y., Hui D.Y. Bile salt stimulated cholesterol esterase increases uptake of high density lipoprotein-associated cholesteryl esters by HepG2 cells. Biochemistry. 35:1996;6657-6663.
123. Li X., Kan H., Lavrentiadou S., Krieger M., Zannis V.I. Reconstituted discoidal apoE-phospholipid particles are ligands for the scavenger receptor BI. The Journal of Biological Chemistry. 277:2002;21149-21157.
124. Li X., Peegel H., Menon K.M.J. Regulation of high density lipoprotein receptor messenger ribonucleic acid expression and cholesterol transport in theca-interstitial cells by insulin and human chorionic gonadotropin. Endocrinology. 142:2001;174-181.
125. Li X.A., Titlow W.B., Jackson B.A., Giltiay N., Nikolova-Karakashian M., Uittenbogaard A., Smart E.J. High density lipoprotein binding to scavenger receptor, class B, type I activates endothelial nitric-oxide synthase in a ceramide-dependent manner. The Journal of Biological Chemistry. 277:2002;11058-11063.
126. Liadaki K., Liu T., Xu S., Ishida B.Y., Duchateaux P.N., Krieger J.P., Kane J., Krieger M., Zannis V.I. Binding of high density lipoprotein (HDL) and discoidal reconstituted HDL to the HDL receptor scavenger receptor class B type I. Effect of lipid association and apoA-I mutations on receptor binding. The Journal of Biological Chemistry. 275:2000;21262-21271.
127. Lisanti M.P., Scherer P.E., Vidugiriene J., Tang Z., Hermanowski-Vosatka A., Tu Y.H., Cook R.F., Sargiacomo M. Characterization of caveolin-rich membrane domains isolated from an endothelial-rich source: Implications for human disease. The Journal of Cell Biology. 126:1994;111-1126.
128. Liu B., Krieger M. Highly purified scavenger receptor class B, type I reconstituted into phosphatidylcholine/cholesterol liposomes mediates high affinity high density lipoprotein binding and selective lipid uptake. The Journal of Biological Chemistry. 277:2002;34125-34135.
129. Liu T., Krieger M., Kan H.Y., Zannis V.I. The effects of mutations in helices 4 and 6 of ApoA-I on scavenger receptor class B type I (SR-BI)-mediated cholesterol efflux suggest that formation of a productive complex between reconstituted high density lipoprotein and SR-BI is required for efficient lipid transport. The Journal of Biological Chemistry. 277:2002;21576-21584.
130. Lobo M.V., Huerta L., Ruiz-Velasco N., Teixeiro E., de la Cueva P., Celdran A., Martin-Hidalgo A., Vega M.A., Bragado R. Localization of the lipid receptors CD36 and CLA-1/SR-BI in the human gastrointestinal tract: Toward the identification of receptors mediating the intestinal absorption of dietary lipids. The Journal of Histochemistry and Cytochemistry. 49:2001;1253-1260.
131. Lopez D., McLean M.P. Sterol regulatory element-binding protein-1a binds to cis elements in the promoter of the rat high density lipoprotein receptor SR-BI gene. Endocrinology. 140:1999;5669-5681.
132. Lopez D., Sanchez M.D., Shea-Eaton W., McLean M.P. Estrogen activates the high-density lipoprotein receptor gene via binding to estrogen response elements and interaction with sterol regulatory element binding protein-1A. Endocrinology. 143:2002;2155-2168.
133. Lopez D., Sandhoff T.W., McLean M.P. Steroidogenic factor-1 mediates cyclic 3′,5′-adenosine monophosphate regulation of the high density lipoprotein receptor. Endocrinology. 140:1999;3034-3044.
134. Lopez D., Shea-Eaton W., Sanchez M.D., McLean M.P. DAX-1 represses the high-density lipoprotein receptor through interaction with positive regulators sterol regulatory element-binding protein-1a and steroidogenic factor-1. Endocrinology. 142:2001;5097-5106.
135. Malerod L., Juvet L.K., Gjoen T., Berg T. The expression of scavenger receptor class B, type I (SR-BI) and caveolin-1 in parenchymal and nonparenchymal liver cells. Cell and Tissue Research. 307:2002;173-180.
136. Malerod L., Juvet L.K., Hanssen-Bauer A., Eskild W., Berg T. Oxysterol-activated LXRalpha/RXR induces hSR-BI-promoter activity in hepatoma cells and preadipocytes. Biochemical and Biophysical Research Communications. 299:2002;916-923.
137. Mardones P., Pilon A., Bouly M., Duran D., Nishimoto T., Arai H., Kozarsky K.F., Altayo M., Miquel J.F., Luc G., Clavey V., Staels B., Rigotti A. Fibrates down-regulate hepatic scavenger receptor class B type I protein expression in mice. The Journal of Biological Chemistry. 278:2003;7884-7890.
138. Mardones P., Strobel P., Miranda S., Leighton F., Quinones V., Amigo L., Rozowski J., Krieger M., Rigotti A. Alpha-tocopherol metabolism is abnormal in scavenger receptor class B type I (SR-BI)-deficient mice. Journal of Nutrition. 132:2002;443-449.
139. Mardones P., Quinones V., Amigo L., Moreno M., Miquel J.F., Schwarz M., Miettinen H.E., Trigatti B., Krieger M., VanPatten S., Cohen D.E., Rigotti A. Hepatic cholesterol and bile acid metabolism and intestinal cholesterol absorption in scavenger receptor class B type I-deficient mice. Journal of Lipid Research. 42:2001;170-180.
140. Marsche G., Hammer A., Oskolkova O., Kozarsky K.F., Sattler W., Malle E. Hypochlorite-modified high lipoprotein, a high-affinity ligand to scavenger receptor class B, type I, impairs high density lipoprotein-dependent selective uptake and reverse cholesterol transport. The Journal of Biological Chemistry. 277:2002;32172-32179.
141. Marsche G., Levak-Frank S., Quehenberger O., Heller R., Sattler W., Malle E. Identification of the human analog of SR-BI and LOX-1 as receptors for hypochlorite-modified high density lipoprotein on human umbilical venous endothelial cells. The FASEB Journal. 15:2001;1095-1097.
142. Martin G., Pilon A., Albert C., Vallé M., Hum D.W., Fruchart J.C., Najib J., Clavey V., Staels B. Comparison of expression and regulation of the high-density lipoprotein receptor SR-BI and the low-density lipoprotein receptor in human adrenocortical carcinoma NCI-H295 cells. European Journal of Biochemistry. 261:1999;481-491.
143. Matveev S., Uittenbogaard A., van der Westhuyzen D.R., Smart E.J. Caveolin-1 negatively regulates SR-BI mediated selective uptake of high-density lipoprotein-derived cholesteryl ester. European Journal of Biochemistry. 268:2001;5609-5616.
144. Matveev S., van der Westhuyzen D.R., Smart E.J. Co-expression of scavenger receptor-BI and caveolin-1 is associated with enhanced selective cholesteryl ester uptake in THP-1 macrophages. Journal of Lipid Research. 40:1999;1647-1654.
145. McLean M.P., Sandhoff T.W. Expression and hormonal regulation of the high-density lipoprotein (HDL) receptor scavenger receptor class B type I messenger ribonucleic acid in the rat ovary. Endocrine. 9:1998;243-252.
146. Miettinen H.E., Rayburn H., Krieger M. Abnormal lipoprotein metabolism and reversible female infertility in HDL receptor (SR-BI)-deficient mice. Journal of Clinical Investigation. 108:2001;1717-1722.
147. Mizutani T., Yamada K., Minegishi T., Miyamoto K. Transcriptional regulation of rat scavenger receptor class B type I gene. The Journal of Biological Chemistry. 275:2000;22512-22519.
148. Morohashi K., Zanger U.M., Honda S., Hara M., Waterman M.R., Omura T. Activation of CYP11A and CYP11B gene promoters by the steroidogenic cell-specific transcription factor, Ad4BP. Molecular Endocrinology. 11:1993;292-304.
149. Mountjoy K.G., Robbins L.S., Mortrud M.T., Cone R.D. The cloning of a family of genes that encode the melanocortin receptors. Science. 257:1992;1248-1251.
150. Murao K., Terpstra V., Green S.R., Kondratenko N., Steinberg D., Quehenberger O. Characterization of CLA-1, a human homologue of rodent scavenger receptor B1, as a receptor for high density lipoprotein and apoptotic thymocytes. The Journal of Biological Chemistry. 272:1997;17551-17557.
151. Murre C., Bain G., van Dijk M.A., Engel I., Furnari B.A., Massari M.E., Matthews J.R., Quong M.W., Rivera R.R., Stuiver M.H. Structure and function of helix-loop-helix proteins. Biochimica et Biophysica Acta. 1218:1994;129-135.
152. Natarajan R., Ghosh S., Grogan W.M. Regulation of the rat neutral cytosolic cholesteryl ester hydrolase promoter by hormones and sterols: A role for nuclear factor-Y in the sterol-mediated response. Journal of Lipid Research. 40:1999;2091-2098.
153. Ng D.S., Francone O.L., Forte T.M., Zhang J., Haghpassand M., Rubin E.M. Disruption of the murine lecithin: Cholesterol acyltransferase gene causes impairment of adrenal lipid delivery and up-regulation of scavenger receptor class B type I. The Journal of Biological Chemistry. 272:1997;15777-15781.
154. Nieland T.J.F., Penman M., Dori L., Krieger M., Kirchhausen T. Discovery of chemical inhibitors of the selective transfer of lipids mediated by the HDL receptor SR-BI. Proceedings of the National Academy of Sciences of the United States of America. 99:2002;15422-15427.
155. Nozaki S., Kashiwagi H., Yamashita S., Nakagawa T., Kostner B., Tomiyama Y., Nakata A., Ishigami M., Miyagawa J., Kameda-Takemura K. Reduced uptake of oxidized low density lipoproteins in monocyte-derived macrophages from CD36-deficient subjects. Journal of Clinical Investigation. 96:1995;1859-1865.
156. Ohgami N., Nagai R., Ikemoto M., Arai H., Kuniyasu A., Horiuchi S., Nakayama H. CD36, a member of the class B scavenger receptor family, as a receptor for advanced glycation end products. The Journal of Biological Chemistry. 276:2001;3195-3202.
157. Ohgami N., Nagai R., Miyazaki A., Ikemoto M., Arai H., Horiuchi S., Nakayama H. Scavenger receptor class B type I-mediated reverse cholesterol transport is inhibited by advanced glycation end products. The Journal of Biological Chemistry. 276:2001;13348-13355.
158. Oquendo P., Hundt E., Lawler J., Seed B. CD36 directly mediates cytoadherence of Plasmodium falciparum parasitized erythrocytes. Cell. 58:1989;95-101.
159. Panousis C.G., Zuckerman S.H. Interferon-gamma induces downregulation of Tangier disease gene (ATP-binding-cassette transporter 1) in macrophage-derived foam cells. Arteriosclerosis, Thrombosis, and Vascular Biology. 20:2000;1565-1571.
160. Paresce D.M., Ghosh R.N., Maxfield F.R. Microglial cells internalize aggregates of the Alzheimer's disease amyloid beta-protein via a scavenger receptor. Neuron. 17:1996;553-565.
161. Parini P., Angelin B., Rudling M. Importance of estrogen receptors in hepatic LDL receptor regulation. Arteriosclerosis, Thrombosis, and Vascular Biology. 17:1997;1800-1805.
162. Parker K.L., Schimmer B.P. Steroidogenic factor-1: A key determinant of endocrine development and function. Endocrine Reviews. 18:1997;361-377.
163. Pilon A., Briand O., Lestavel S., Copin C., Majd Z., Fruchart J.C., Castro G., Clavey V. Apolipoprotein AII enrichment of HDL enhances their affinity for class B type I scavenger receptor but inhibits specific cholesteryl ester uptake. Arteriosclerosis, Thrombosis, and Vascular Biology. 20:2000;1074-1081.
164. Pittman R.C., Knecht T.P., Rosenbaum M.S., Taylor C.A. Jr. A non-endocytic mechanism for the selective uptake of high density lipoprotein-associated cholesterol esters. The Journal of Biological Chemistry. 262:1987;2443-2450.
165. Pohl J., Ring A., Stremmel W. Uptake of long-chain fatty acids in HepG2 cells involves caveolae: Analysis of a novel pathway. Journal of Lipid Research. 43:2002;1390-1399.
166. Reaven E., Boyles E.J., Spicher M., Azhar S. Evidence for surface entrapment of cholesterol-rich lipoproteins in luteinized ovary. Arteriosclerosis. 8:1988;298-309.
167. Reaven E., Chan L., Nomoto A., Leers-Sucheta S., Azhar S. Expression and microvillar localization of scavenger receptor class B, type I (SR-BI) and selective cholesteryl ester uptake in Leydig cells from rat testis. Journal of Lipid Research. 41:2000;343-356.
168. Reaven E., Leers-Sucheta S., Nomoto A., Azhar S. Expression of scavenger receptor class B type I (SR-BI) promotes microvillar channel formation and selective cholesteryl ester transport in a heterologous reconstituted system. Proceedings of the National Academy of Sciences of the United States of America. 98:2001;1613-1618.
169. Reaven E., Luo Y., Nomoto A., Temel R., Williams D.L., van der Westhuyzen D.R., Azhar S. The selective pathway and a high-density lipoprotein receptor (SR-BI) in ovarian granulosa cells of the mouse. Biochimica et Biophysica Acta. 1436:1999;565-576.
170. Reaven E., Nomoto A., Leers-Sucheta S., Temel R.E., Williams D.L., Azhar S. Expression and microvillar localization of scavenger receptor, class B, type I (a high-density lipoprotein receptor) in luteinized and hormone-desensitized rat ovarian models. Endocrinology. 139:1998;2847-2856.
171. Reaven E., Spicher M., Azhar S. Microvillar channels: A unique plasma membrane compartment for concentrating lipoproteins on the surface of rat adrenal cortical cells. Journal of Lipid Research. 30:1989;1551-1560.
172. Rhainds, D., Brodeur, M., Lapointe, J., Charpentier, D., Falstrault, L., & Brissette, L. The role of human and mouse hepatic scavenger receptor class B type I (SR-BI) in the selective uptake of low density lipoprotein cholesteryl esters. Biochemistry, in press.
173. Rhainds D., Falstrault L., Tremblay C., Brissette L. Uptake and fate of class B scavenger receptor ligands in HepG2 cells. European Journal of Biochemistry. 261:1999;227-235.
174. Rigotti A., Acton S.L., Krieger M. The class B scavenger receptors SR-BI and CD36 are receptors for anionic phospholipids. The Journal of Biological Chemistry. 270:1995;16221-16224.
175. Rigotti A., Edelman E.R., Seifert P., Iqbal S.N., DeMattos R.B., Temel R.E., Krieger M., Williams D.L. Regulation by adrenocorticotropic hormone of the in vivo expression of scavenger receptor class B type I (SR-BI), a high density lipoprotein receptor, in steroidogenic cells of the murine adrenal gland. The Journal of Biological Chemistry. 271:1996;33545-33549.
176. Rigotti A., Trigatti B.L., Penman M., Rayburn H., Herz J., Krieger M. A targeted mutation in the murine gene encoding the high density lipoprotein (HDL) receptor scavenger receptor class B type I reveals its key role in HDL metabolism. Proceedings of the National Academy of Sciences of the United States of America. 94:1997;12610-12615.
177. Rinninger F., Brundert M., Brosch I., Donarski N., Budzinski R.M., Greten H. Lipoprotein lipase mediates an increase in selective uptake of HDL-associated cholesteryl esters by cells in culture independent of scavenger receptor BI. Journal of Lipid Research. 42:2001;1740-1751.
178. Rinninger F., Jaeckle S., Pittman R.C. A pool of reversibly cell associated cholesteryl esters involved in the selective uptake of cholesteryl esters from high-density lipoproteins by HepG2 hepatoma cells. Biochimica et Biophysica Acta. 1166:1993;275-283.
179. Rinninger F., Kaiser T., Mann W.A., Meyer N., Greten H., Beisiegel U. Lipoprotein lipase mediates an increase in the selective uptake of high density lipoprotein-associated cholesteryl esters by hepatic cells in culture. Journal of Lipid Research. 39:1998;1335-1348.
180. Rinninger F., Kaiser T., Windler E., Greten H., Fruchart J.C., Castro G. Selective uptake of cholesteryl esters from high-density lipoprotein-derived LpA-I and LpA-I:A-II particles by hepatic cells in culture. Biochimica et Biophysica Acta. 1393:1998;277-291.
181. Rinninger F., Mann W.A., Kaiser T., Ahle S., Meyer N., Greten H. Hepatic lipase mediates an increase in selective uptake of high-density lipoprotein-associated cholesteryl esters by human Hep3B hepatoma cells in culture. Atherosclerosis. 141:1998;273-285.
182. Rodrigueza W., Thuahnai S.T., Temel R.E., Lund-Katz S., Phillips M.C., Williams D.L. Mechanism of scavenger receptor class B type I-mediated selective uptake of cholesteryl esters from high density lipoprotein to adrenal cells. The Journal of Biological Chemistry. 274:1999;20344-20350.
183. Rogler G., Herold G., Fahr C., Fahr M., Rogler D., Reimann F.M., Stange E.F. High-density lipoprotein 3 retroendocytosis: A new lipoprotein pathway in the enterocyte (CaCo-2). Gastroenterology. 103:1992;469-480.
184. Rudling M., Norstedt G., Olivecrona H., Rheiner E., Gustafsson J.A., Angelin B. Importance of growth hormone for the induction of hepatic low density lipoprotein receptors. Proceedings of the National Academy of Sciences of the United States of America. 89:1992;6983-6987.
185. Scarselli E., Ansuini H., Cerino R., Roccasecca R.M., Acali S., Filocamo G., Traboni C., Nicosia A., Cortese R., Vitelli A. The human scavenger receptor class B type I is a novel candidate receptor for the hepatitis C virus. The EMBO Journal. 21:2002;5017-5025.
186. Schmitz G., Robenek H., Lohmann U., Assmann G. Interaction of high density lipoproteins with cholesteryl ester-laden macrophages: Biochemical and morphological characterization of cell surface receptor binding, endocytosis and resecretion of high density lipoproteins by macrophages. The EMBO Journal. 4:1985;613-622.
187. Schoonjans K., Annicotte J.S., Huby T., Botrugno O.A., Fayard E., Ueda Y., Chapman J., Auwerx J. Liver receptor homolog 1 controls the expression of the scavenger receptor class B type I. The EMBO Report. 3:2002;31181-31187.
188. Sehayek E., Ono J.G., Shefer S., Nguyen L.B., Wang N., Batta A.K., Salen G., Smith J.D., Tall A.R., Breslow J.L. Biliary cholesterol excretion: A novel mechanism that regulates dietary cholesterol absorption. Proceedings of the National Academy of Sciences of the United States of America. 95:1998;10194-10199.
189. Seo T., Al-Haideri M., Treskova E., Worgall T.S., Kako Y., Goldberg I.J., Deckelbaum R.J. Lipoprotein lipase-mediated selective uptake from low density lipoprotein requires cell surface proteoglycans and is independent of scavenger receptor class B type 1. The Journal of Biological Chemistry. 275:2000;30355-30362.
190. Seo T., Velez-Carrasco W., Qi K., Hall M., Worgall T.S., Johnson R.A., Deckelbaum R.J. Selective uptake from LDL is stimulated by unsaturated fatty acids and modulated by cholesterol content in the plasma membrane: Role of plasma membrane composition in regulating non-SR-BI-mediated selective lipid transfer. Biochemistry. 41:2002;7885-7894.
191. Shah V., Cao S., Hendrickson H., Yao J., Katusic Z.S. Regulation of hepatic eNOS by caveolin and calmodulin after bile duct ligation in rats. American Journal of Physiology, Gastrointestinal and Liver Physiology. 280:2001;G1209-G1216.
192. Shea-Eaton W., Lopez D., McLean M.P. Yin Yang 1 protein negatively regulates high-density lipoprotein receptor gene transcription by disrupting binding of sterol regulatory element binding protein to the sterol regulatory element. Endocrinology. 142:2001;49-58.
193. Shi Y., Lee J.S., Galvin K.M. Everything you always wanted to know about Yin Yang 1. Biochimica et Biophysica Acta. 1332:1997;F49-F66.
194. Shiratsuchi A., Kawasaki Y., Ikemoto M., Arai H., Nakanishi Y. Role of class B scavenger receptor type I in phagocytosis of apoptotic rat spermatogenic cells by Sertoli cells. The Journal of Biological Chemistry. 274:1999;5901-5908.
195. Silver D.L. A carboxyl-terminal PDZ-interacting domain of scavenger receptor B, type I is essential for cell surface expression in liver. The Journal of Biological Chemistry. 277:2002;34042-34047.
196. Silver D.L., Tall A.R. The cellular biology of scavenger receptor class B type I. Current Opinion in Lipidology. 12:2001;497-504.
197. Silver D.L., Wang N., Xiao X., Tall A. High density lipoprotein (HDL) particle uptake mediated by scavenger receptor class B type 1 results in selective sorting of HDL cholesterol from protein and polarized cholesterol secretion. The Journal of Biological Chemistry. 276:2001;25287-25293.
198. Sirianni R., Seely J.B., Attia G., Stocco D.M., Carr B.R., Pezzi V., Rainey W.E. Liver receptor homologue-1 is expressed in human steroidogenic tissues and activates transcription of genes encoding steroidogenic enzymes. Journal of Endocrinology. 174:2002;R13-R17.
199. Smart E.J., Graf G.A., McNiven M.A., Sessa W.C., Engelman J.A., Sherer P.E., Okamoto T., Lisanti M.P. Caveolins, liquid-ordered domains, and signal transduction. Molecular and Cellular Biology. 19:1999;7289-7304.
200. Spady D.K., Keaney D.M., Hobbs H.H. Polyunsaturated fatty acids up-regulate hepatic scavenger receptor B1 (SR-BI) expression and HDL cholesteryl ester uptake in the hamster. Journal of Lipid Research. 40:1999;1384-1394.
201. Sparrow C.P., Pittman R.C. Cholesterol esters selectively taken up from high-density lipoproteins are hydrolyzed extralysosomally. Biochimica et Biophysica Acta. 1043:1990;203-210.
202. Srivastava R.A.K., Baumann D., Schonfeld G. In vivo regulation of low-density lipoprotein receptors by estrogen differs at the post-transcriptional levels in rat and mouse. European Journal of Biochemistry. 216:1993;527-538.
203. Stangl H., Cao G., Wyne K.L., Hobbs H.H. Scavenger receptor, class B, type I-dependent stimulation of cholesterol esterification by high density lipoproteins, low density lipoproteins, and nonlipoprotein cholesterol. The Journal of Biological Chemistry. 273:1998;31002-31008.
204. Stangl H., Graf G.A., Yu L., Cao G., Wyne K. Effect of estrogen on scavenger receptor BI expression in the rat. Journal of Endocrinology. 175:2002;663-672.
205. Stangl H., Hyatt M., Hobbs H.H. Transport of lipids from high and low density lipoproteins via scavenger receptor-BI. The Journal of Biological Chemistry. 274:1999;32692-32698.
206. Sun Y., Wang N., Tall A.R. Regulation of adrenal scavenger receptor-BI expression by ACTH and cellular cholesterol pools. Journal of Lipid Research. 40:1999;1799-1805.
207. Svensson P.A., Johnson M.C.S., Ling C., Carlsson L.M.S., Billig H., Carlsson B. Scavenger receptor class B type I in the rat ovary: Possible role in high density lipoprotein cholesterol uptake and in the recognition of apoptotic granulosa cells. Endocrinology. 140:1999;2494-2500.
208. Swarnakar S., Beers J., Strickland D.K., Azhar S., Williams D.L. The apolipoprotein E-dependent low density lipoprotein cholesteryl ester selective uptake pathway in murine adrenocortical cells involves chondroitin sulfate proteoglycans and an alpha 2-macroglobulin receptor. The Journal of Biological Chemistry. 276:2001;21121-21128.
209. Swarnakar S., Reyland M.E., Deng J., Azhar S., Williams D.L. Selective uptake of low density lipoprotein-cholesteryl ester is enhanced by inducible apolipoprotein E expression in cultured mouse adrenocortical cells. The Journal of Biological Chemistry. 273:1998;12140-12147.
210. Swarnakar S., Temel R.E., Connelly M.A., Azhar S., Williams D.L. Scavenger receptor class B, type I, mediates selective uptake of low density lipoprotein cholesteryl ester. The Journal of Biological Chemistry. 274:1999;29733-29739.
211. Tall A.R., Costet P., Wang N. Regulation and mechanism of macrophage cholesterol efflux. Journal of Clinical Investigation. 110:2002;899-904.
212. Tang Y., Taylor K.T., Sobieski D.A., Medved E.S., Lipsky R.H. Identification of a human CD36 isoform produced by exon skipping. Conservation of exon organization and pre-mRNA splicing patterns with a CD36 gene family member, CLA-1. The Journal of Biological Chemistry. 269:1994;6011-6015.
213. Tao N., Wagner S.J., Lublin D.M. CD36 is palmitoylated on both N- and C-terminal cytoplasmic tails. The Journal of Biological Chemistry. 271:1996;22315-22320.
214. Temel R.E., Trigatti B.L., DeMattos R.B., Azhar S., Krieger M., Williams D.L. Scavenger receptor class B, type I (SR-BI) is the major route for the delivery of high density lipoprotein cholesterol to the steroidogenic pathway in cultured mouse adrenocortical cells. Proceedings of the National Academy of Sciences of the United States of America. 94:1997;13600-13605.
215. Temel R.E., Walzem R.L., Banka C.L., Williams D.L. Apolipoprotein A-I is necessary for the in vivo formation of high density lipoprotein competent for scavenger receptor BI-mediated cholesteryl ester-selective uptake. The Journal of Biological Chemistry. 277:2002;26565-26572.
216. Thuahnai S.T., Lund-Katz S., Williams D.L., Phillips M.C. Scavenger receptor class B, type I-mediated uptake of various lipids into cells. Influence of the nature of the donor particle interaction with the receptor. The Journal of Biological Chemistry. 276:2001;43801-43808.
217. Tontonoz P., Nagy L., Alvarez J.G., Thomazy V.A., Evans R.M. PPARgamma promotes monocyte/macrophage differentiation and uptake of oxidized LDL. Cell. 93:1998;241-252.
218. Trigatti B.L., Rayburn H., Vinals M., Braun A., Miettinen H., Penman M., Hertz M., Schrenzel M., Amigo L., Rigotti A., Krieger M. Influence of the high density lipoprotein receptor SR-BI on reproductive and cardiovascular pathophysiology. Proceedings of the National Academy of Sciences of the United States of America. 96:1999;9322-9327.
219. Trigatti B.L., Rigotti A., Braun A. Cellular and physiological roles of SR-BI, a lipoprotein receptor which mediates selective lipid uptake. Biochimica et Biophysica Acta. 1529:2000;276-286.
220. Truong, T. Q., Aubin, D., Bourgeois, P., & Brissette, L. (2001). Caveolin-1 expression in HepG2 cells increases the selective uptake of cholesteryl esters from HDL and reduces that from LDL. Circulation, 104, II-232, Abstract 1115.
221. Tsuruoka H., Khovidhunkit W., Brown B.E., Fluhr J.W., Elias P.M., Feingold K.R. Scavenger receptor class B type I is expressed in cultured keratinocytes and epidermis. Regulation in response to changes in cholesterol homeostasis and barrier requirements. The Journal of Biological Chemistry. 277:2002;2916-2922.
222. Ueda Y., Gong E., Royer L., Cooper P.N., Francone O.L., Rubin E.M. Relationship between expression levels and atherogenesis in scavenger receptor class B, type I transgenics. The Journal of Biological Chemistry. 275:2000;20368-20373.
223. Ueda Y., Royer L., Gong E., Zhang J., Cooper P.N., Francone O., Rubin E.M. Lower plasma levels and accelerated clearance of high density lipoprotein (HDL) and non-HDL cholesterol in scavenger receptor class B type I transgenic mice. The Journal of Biological Chemistry. 274:1999;7165-7171.
224. Uittenbogaard A., Everson W.V., Matveev S.V., Smart E.J. Cholesteryl ester is transported from caveolae to internal membranes as part of a caveolin-annexin II lipid-protein complex. The Journal of Biological Chemistry. 277:2002;4925-4931.
225. Uittenbogaard A., Shaul P.W., Yuhanna I.S., Blair A., Smart E.J. High density lipoprotein prevents oxidized low density lipoprotein-induced inhibition of endothelial nitric-oxide synthase localization and activation in caveolae. The Journal of Biological Chemistry. 275:2000;11278-11283.
226. Urban S., Zieseniss S., Werder M., Hauser H., Budzinski R., Engelmann B. Scavenger receptor BI transfers major lipoprotein-associated phospholipids into the cells. The Journal of Biological Chemistry. 275:2000;33409-33415.
227. Varban M.L., Rinninger F., Wang N., Fairchild-Huntress V., Dunmore J.H., Fang Q., Gosselin M.L., Dixon K.L., Deeds J.D., Acton S.L., Tall A.R., Huszar D. Targeted mutation reveals a central role for SR-BI in hepatic selective uptake of high density lipoprotein cholesterol. Proceedings of the National Academy of Sciences of the United States of America. 95:1998;4619-4624.
228. Vassiliou G., Benoist F., Lau P., Kavaslar G.N., McPherson R. The low density lipoprotein receptor-related protein contributes to selective uptake of high density lipoprotein cholesteryl esters by SW872 liposarcoma cells and primary human adipocytes. The Journal of Biological Chemistry. 276:2001;48823-48830.
229. Vieira-van Bruggen D., Kalkman I., van Gent T., van Tol A., Jansen H. Induction of adrenal scavenger receptor BI and increased high density lipoprotein-cholesteryl ether uptake by in vivo inhibition of hepatic lipase. The Journal of Biological Chemistry. 273:1998;32038-32041.
230. Vinals M., Xhu S., Vasile E., Krieger M. Identification of the N-linked glycosylation sites on the high density lipoprotein (HDL) receptor SR-BI and assessment of their effects on HDL binding and selective lipid uptake. The Journal of Biological Chemistry. 278:2003;5325-5332.
231. Voshol P.J., Schwarz M., Rigotti A., Krieger M., Groen A.K., Kuipers F. Down-regulation of intestinal scavenger receptor class B, type I (SR-BI) expression in rodents under conditions of deficient bile delivery to the intestine. The Biochemical Journal. 356:2001;317-325.
232. Wang N., Arai T., Ji Y., Rinninger F., Tall A.R. Liver-specific overexpression of scavenger receptor BI decreases levels of very low density lipoprotein ApoB, low density lipoprotein ApoB, and high density lipoprotein in transgenic mice. The Journal of Biological Chemistry. 273:1998;32920-32926.
233. Wang D.Q., Carey M.C. Susceptibility to murine cholesterol gallstone formation is not affected by partial disruption of theHDL receptor SR-BI. Biochimica et Biophysica Acta. 1583:2002;141-150.
234. Wang N., Silver D.L., Thiele C., Tall A.R. ATP-binding cassette transporter A1 (ABCA1) functions as a cholesterol efflux regulatory protein. The Journal of Biological Chemistry. 276:2001;23742-23747.
235. Wang N., Weng W., Breslow J.L., Tall A.R. Scavenger receptor BI (SR-BI) is up-regulated in adrenal gland in apolipoprotein A-I and hepatic lipase knock-out mice as a response to depletion of cholesterol stores. In vivo evidence that SR-BI is a functional high density lipoprotein receptor under feedback control. The Journal of Biological Chemistry. 271:1996;21001-21004.
236. Webb N.R., Cai L., Ziemba K.S., Yu J., Kindy M.S., van der Westhuyzen D.R., de Beer F.C. The fate of HDL particles in vivo after SR-BI-mediated selective lipid uptake. Journal of Lipid Research. 43:2002;1890-1898.
237. Webb N.R., Connell P.M., Graf G.A., Smart E.J., de Villiers W.J., de Beer F.C., van der Westhuyzen D.R. SR-BII, an isoform of the scavenger receptor BI containing an alternate cytoplasmic tail, mediates lipid transfer between high density lipoprotein and cells. The Journal of Biological Chemistry. 273:1998;15241-15248.
238. Webb N.R., de Beer M.C., Yu J., Kindy M.S., Daugherty A., van der Westhuyzen D.R., de Beer F.C. Overexpression of SR-BI by adenoviral vector promotes clearance of apoA-I, but not apoB, in human apoB transgenic mice. Journal of Lipid Research. 43:2002;1421-1428.
239. Webb N.R., de Villiers W.J., Connell P.M., de Beer F.C., van der Westhuyzen D.R. Alternative forms of the scavenger receptor BI (SR-BI). Journal of Lipid Research. 38:1997;1490-1495.
240. Welch C.L., Xia Y.R., Gu L.J., Machleder D., Mehrabian M., Wen P.Z., Webb N., de Villiers W.J., van der Westhuyzen D.R., Lusis A.J. Srb1 maps to mouse chromosome 5 in a region harboring putative QTLs for plasma lipoprotein levels. Mammalian Genome. 8:1997;942-944.
241. Werder M., Han C.H., Wehrli E., Bimmler D., Schulthess G., Hauser H. Role of scavenger receptors SR-BI and CD36 in selective sterol uptake in the small intestine. Biochemistry. 40:2001;11643-11650.
242. Williams D.L., Connelly M.A., Temel R.E., Swarnakar S S., Phillips M.C., de la Llera-Moya M., Rothblat G.H. Scavenger receptor BI and cholesterol trafficking. Current Opinion in Lipidology. 10:1999;329-339.
243. Williams D.L., de la Llera-Moya M., Thuahnai S., Lund-Katz S., Connelly M.A., Azhar S., Anantharamaiah G.M., Philips M.C. Binding and cross-linking studies show that scavenger receptor BI interacts with multiple sites in apolipoprotein A-I and identify the class A amphipathic alpha-helix as a recognition motif. The Journal of Biological Chemistry. 275:2000;18897-18904.
244. Williams D.L., Wong J.S., Hamilton R.L. SR-BI is required for microvillar channel formation and the localization of HDL particles to the surface of adrenocortical cells in vivo. Journal of Lipid Research. 43:2002;544-549.
245. Williams D.L., Wong J.S., Wissig S.L., Hamilton R.L. Cell surface "blanket" of apolipoprotein E on rat adrenocortical cells. Journal of Lipid Research. 36:1995;745-758.
246. Witt W., Kolleck I., Fechner H., Sinha P., Rustow B. Regulation by Vitamin E of the scavenger receptor BI in rat liver and HepG2 cells. Journal of Lipid Research. 41:2000;2009-2016.
247. Woodford J.K., Behnke W.D., Schroeder F. Liver fatty acid binding protein enhances sterol transfer by membrane interaction. Molecular and Cellular Biochemistry. 152:1995;51-62.
248. Wyne K.L., Woollett L.A. Transport of maternal LDL and HDL to the fetal membranes and placenta of the Golden Syrian hamster is mediated by receptor-dependent and receptor-independent processes. Journal of Lipid Research. 39:1998;518-530.
249. Xu S., Laccotripe M., Huang X., Rigotti A., Zannis V., Krieger M. Apolipoproteins of HDL can directly mediate binding to the scavenger receptor SR-BI, an HDL receptor that mediates selective lipid uptake. Journal of Lipid Research. 38:1997;1289-1298.
250. Yancey P.G., de la Llera-Moya M., Swarnakar S., Monzo P., Klein S.M., Connelly M.A., Johnson W.J., Williams D.L., Rothblat G.H. High density lipoprotein phospholipid composition is a major determinant of the bi-directional flux and net movement of cellular free cholesterol mediated by scavenger receptor BI. The Journal of Biological Chemistry. 275:2000;36596- 36604.
251. Yeh Y.C., Hwang G.Y., Liu I.P., Yang V.C. Identification and expression of scavenger receptor SR-BI in endothelial cells and smooth muscle cells of rat aorta in vitro and in vivo. Atherosclerosis. 161:2002;95-103.
252. Yuhanna I.S., Zhu Y., Cox B.E., Hahner L.D., Osborne-Lawrence S., Lu P., Marcel Y.L., Anderson R.G., Mendelsohn M.E., Hobbs H.H., Shaul P.W. High-density lipoprotein binding to scavenger receptor-BI activates endothelial nitric oxide synthase. Nature Medicine. 7:2001;853-857.