A diterpenoid compound, excisanin A, inhibits the invasive behavior of breast cancer cells by modulating the integrin β1/FAK/PI3K/AKT/β- catenin signaling

Life Sciences

Volumn 93, Issue 18-19, 2013, Pages 655-663

  Qin, Juan ^a   Tang, Jun ^a   Jiao, Lin ^a   Ji, Jiao ^a   Chen, Wen Dan ^a   Feng, Gong Kan ^a   Gao, You Heng ^b   Zhu, Xiao Feng ^a   Deng, Rong ^a  

^a SUN YAT SEN UNIVERSITY CANCER CENTER   (China)

^b GUANGZHOU UNIVERSITY OF CHINESE MEDICINE   (China)

Author keywords

Diterpenoid; Excisanin A; FAK; Integrin 1; Invasion; MMPs

Indexed keywords

BETA CATENIN; BETA1 INTEGRIN; DITERPENOID; EXCISANIN A; FOCAL ADHESION KINASE; GELATINASE A; GELATINASE B; GLYCOGEN SYNTHASE KINASE 3BETA; LUCIFERASE; LYMPHOID ENHANCER FACTOR 1; MESSENGER RNA; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; SMALL INTERFERING RNA; UNCLASSIFIED DRUG;

ARTICLE; ASSAY; BREAST CANCER; BREAST CANCER CELL; CANCER CELL; CELL ADHESION; CELL INVASION; CELL MIGRATION; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME PHOSPHORYLATION; HUMAN; HUMAN CELL; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; RNA INTERFERENCE; WESTERN BLOTTING; WOUND HEALING;

DITERPENOID; EXCISANIN A; FAK; INTEGRIN Β1; INVASION; MMPS;

BETA CATENIN; BREAST NEOPLASMS; CELL LINE, TUMOR; CELL MOVEMENT; DITERPENES; FEMALE; FOCAL ADHESION KINASE 1; HUMANS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MEMBRANE PROTEINS; NEOPLASM INVASIVENESS; PHOSPHATIDYLINOSITOL 3-KINASES; PROTO-ONCOGENE PROTEINS C-AKT;

ISODON;

EID: 84886084572     PISSN: 00243205     EISSN: 18790631     Source Type: Journal    
DOI: 10.1016/j.lfs.2013.09.002     Document Type: Article

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