메뉴 건너뛰기




Volumn 282, Issue , 2015, Pages 209-217

Mechanisms of insulin resistance in the amygdala: Influences on food intake

Author keywords

Amygdala; ER stress; Food intake; Insulin signaling; Obesity; Protein kinase C theta

Indexed keywords

FATTY ACID DERIVATIVE; I KAPPA B KINASE BETA; INSULIN; MESSENGER RNA; NEUROPEPTIDE Y; OXYTOCIN; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; PROTEIN KINASE C THETA; SATURATED FATTY ACID; STRESS ACTIVATED PROTEIN KINASE; TRIACYLGLYCEROL; PROTEIN KINASE C;

EID: 84921657749     PISSN: 01664328     EISSN: 18727549     Source Type: Journal    
DOI: 10.1016/j.bbr.2015.01.003     Document Type: Review
Times cited : (50)

References (74)
  • 1
    • 79957899067 scopus 로고    scopus 로고
    • Digging deeper into obesity
    • Ahima R.S. Digging deeper into obesity. J Clin Invest 2011, 121:2076-2079.
    • (2011) J Clin Invest , vol.121 , pp. 2076-2079
    • Ahima, R.S.1
  • 2
    • 0029364825 scopus 로고
    • Changing diet and exercise behaviors in individuals at risk for gain
    • Wing R.R. Changing diet and exercise behaviors in individuals at risk for gain. Obes Res 1995, 3:277-282.
    • (1995) Obes Res , vol.3 , pp. 277-282
    • Wing, R.R.1
  • 3
    • 77953286014 scopus 로고    scopus 로고
    • Social inequalities in food exposure around schools in urban area
    • Kestens Y., Daniel M. Social inequalities in food exposure around schools in urban area. Am J Prev Med 2010, 39:33-40.
    • (2010) Am J Prev Med , vol.39 , pp. 33-40
    • Kestens, Y.1    Daniel, M.2
  • 4
    • 41549108590 scopus 로고    scopus 로고
    • PDK1 deficiency in POMC-expressing cells reveals FOXO1-dependent and -independent pathways in control of energy homeostasis and stress response
    • Belgardt B.F., Husch A., Rother E., Ernst M.B., Wunderlich F.T., Hampel B., et al. PDK1 deficiency in POMC-expressing cells reveals FOXO1-dependent and -independent pathways in control of energy homeostasis and stress response. Cell Metab 2008, 7:291-301.
    • (2008) Cell Metab , vol.7 , pp. 291-301
    • Belgardt, B.F.1    Husch, A.2    Rother, E.3    Ernst, M.B.4    Wunderlich, F.T.5    Hampel, B.6
  • 5
    • 68949120737 scopus 로고    scopus 로고
    • Control of energy homeostasis by insulin and leptin: targeting the arcuate nucleus and beyond
    • Könner A.C., Klöckener T., Brüning J.C. Control of energy homeostasis by insulin and leptin: targeting the arcuate nucleus and beyond. Physiol Behav 2009, 97:632-638.
    • (2009) Physiol Behav , vol.97 , pp. 632-638
    • Könner, A.C.1    Klöckener, T.2    Brüning, J.C.3
  • 6
    • 84856450553 scopus 로고    scopus 로고
    • Altered hypothalamic function in diet-induced obesity
    • Velloso L.A., Schwartz M.W. Altered hypothalamic function in diet-induced obesity. Int J Obes 2011, 35:1455-1465.
    • (2011) Int J Obes , vol.35 , pp. 1455-1465
    • Velloso, L.A.1    Schwartz, M.W.2
  • 7
    • 79955584321 scopus 로고    scopus 로고
    • Leptin and the central nervous system control of glucose metabolism
    • Morton G.J., Schwartz M.W. Leptin and the central nervous system control of glucose metabolism. Physiol Rev 2011, 91:389-411.
    • (2011) Physiol Rev , vol.91 , pp. 389-411
    • Morton, G.J.1    Schwartz, M.W.2
  • 8
    • 79958026765 scopus 로고    scopus 로고
    • Role for insulin signaling in catecholaminergic neurons in control of energy homeostasis
    • Könner A.C., Hess S., Tovar S., Mesaros A., Sánchez-Lasheras C., Evers N., et al. Role for insulin signaling in catecholaminergic neurons in control of energy homeostasis. Cell Metab 2011, 13:720-728.
    • (2011) Cell Metab , vol.13 , pp. 720-728
    • Könner, A.C.1    Hess, S.2    Tovar, S.3    Mesaros, A.4    Sánchez-Lasheras, C.5    Evers, N.6
  • 9
    • 0030748457 scopus 로고    scopus 로고
    • The insulin signaling system and the IRS proteins
    • White M.F. The insulin signaling system and the IRS proteins. Diabetologia 1997, 40:S2-S17.
    • (1997) Diabetologia , vol.40 , pp. S2-S17
    • White, M.F.1
  • 12
    • 0036953551 scopus 로고    scopus 로고
    • Neuropeptides, food intake and body weight regulation: a hypothalamic focus
    • Hillebrand J.J., de Wied D., Adan R.A. Neuropeptides, food intake and body weight regulation: a hypothalamic focus. Peptides 2002, 23:2283-2306.
    • (2002) Peptides , vol.23 , pp. 2283-2306
    • Hillebrand, J.J.1    de Wied, D.2    Adan, R.A.3
  • 13
    • 0032458614 scopus 로고    scopus 로고
    • CNS regulation of energy balance and body weight: insights from rodent models
    • Elmquist J.K. CNS regulation of energy balance and body weight: insights from rodent models. Lab Anim Sci 1998, 48:630-637.
    • (1998) Lab Anim Sci , vol.48 , pp. 630-637
    • Elmquist, J.K.1
  • 14
    • 0037458468 scopus 로고    scopus 로고
    • Expression of receptors for insulin and leptin in the ventral tegmental area/substantia nigra (VTA/SN) of the rat
    • Figlewicz S.B., Evans S.B., Murphy J., Hoen M., Baskin D.G. Expression of receptors for insulin and leptin in the ventral tegmental area/substantia nigra (VTA/SN) of the rat. Brain Res 2003, 964:107-115.
    • (2003) Brain Res , vol.964 , pp. 107-115
    • Figlewicz, S.B.1    Evans, S.B.2    Murphy, J.3    Hoen, M.4    Baskin, D.G.5
  • 15
    • 0035879333 scopus 로고    scopus 로고
    • Involvement of human amygdala and orbitofrontal cortex in hunger-enhanced memory for food stimuli
    • Morris J.S., Dolan R.J. Involvement of human amygdala and orbitofrontal cortex in hunger-enhanced memory for food stimuli. J Neurosci 2001, 21:5304-5310.
    • (2001) J Neurosci , vol.21 , pp. 5304-5310
    • Morris, J.S.1    Dolan, R.J.2
  • 16
    • 0042932360 scopus 로고    scopus 로고
    • Encoding predictive reward value in human amygdala and orbitofrontal cortex
    • Gottfried J.A., O'Doherty J., Dolan R.J. Encoding predictive reward value in human amygdala and orbitofrontal cortex. Science 2003, 301:1104-1107.
    • (2003) Science , vol.301 , pp. 1104-1107
    • Gottfried, J.A.1    O'Doherty, J.2    Dolan, R.J.3
  • 17
    • 34547828087 scopus 로고    scopus 로고
    • Modulation of food reward by adiposity signals
    • Figlewicz D.P., Naleid A.M., Sipols A.J. Modulation of food reward by adiposity signals. Physiol Behav 2007, 91:473-478.
    • (2007) Physiol Behav , vol.91 , pp. 473-478
    • Figlewicz, D.P.1    Naleid, A.M.2    Sipols, A.J.3
  • 18
    • 4444358209 scopus 로고    scopus 로고
    • The amygdala is critical for opioid-mediated binge eating of fat
    • Will M.J., Franzblau E.B., Kelley A.E. The amygdala is critical for opioid-mediated binge eating of fat. Neuroreport 2004, 15:1857-1860.
    • (2004) Neuroreport , vol.15 , pp. 1857-1860
    • Will, M.J.1    Franzblau, E.B.2    Kelley, A.E.3
  • 19
    • 84893008618 scopus 로고    scopus 로고
    • Influence of feeding state on neurofunctional differences between individuals who are obese and normal weight: a meta-analysis of neuroimaging studies
    • Kennedy J., Dimitropoulos A. Influence of feeding state on neurofunctional differences between individuals who are obese and normal weight: a meta-analysis of neuroimaging studies. Appetite 2014, 75:103-109.
    • (2014) Appetite , vol.75 , pp. 103-109
    • Kennedy, J.1    Dimitropoulos, A.2
  • 21
    • 42449159885 scopus 로고    scopus 로고
    • Peptide YY levels are associated with appetite suppression in response to long-chain fatty acids
    • Stoeckel L.E., Weller R.E., Giddings M., Cox J.E. Peptide YY levels are associated with appetite suppression in response to long-chain fatty acids. Physiol Behav 2008, 93:289-295.
    • (2008) Physiol Behav , vol.93 , pp. 289-295
    • Stoeckel, L.E.1    Weller, R.E.2    Giddings, M.3    Cox, J.E.4
  • 22
    • 78049327096 scopus 로고    scopus 로고
    • Distinct modulatory effects of satiety and sibutramine on brain responses to food images in humans: a double dissociation across hypothalamus, amygdala
    • J Neurosci
    • Fletcher PC, Napolitano A, Skeggs A, Miller SR, Delafont B, Cambridge VC de Wit S, et al. Distinct modulatory effects of satiety and sibutramine on brain responses to food images in humans: a double dissociation across hypothalamus, amygdala, and ventral striatum. J Neurosci 2010;30:14346-55.
    • (2010) ventral striatum , vol.30 , pp. 14346-14355
    • Fletcher, P.C.1    Napolitano, A.2    Skeggs, A.3    Miller, S.R.4    Delafont, B.5    Cambridge, V.C.6    de Wit, S.7
  • 23
    • 0032778683 scopus 로고    scopus 로고
    • Serotonergic modulation of neurotransmission in the rat basolateral amygdala
    • Rainnie D.G. Serotonergic modulation of neurotransmission in the rat basolateral amygdala. J Neurophysiol 1999, 82:69-85.
    • (1999) J Neurophysiol , vol.82 , pp. 69-85
    • Rainnie, D.G.1
  • 24
    • 42649116436 scopus 로고    scopus 로고
    • Ghrelin modulates brain activity in areas that control appetitive behavior
    • Malik S., McGlon F., Bedrossian D., Dagher A. Ghrelin modulates brain activity in areas that control appetitive behavior. Cell Metab 2008, 7:400-409.
    • (2008) Cell Metab , vol.7 , pp. 400-409
    • Malik, S.1    McGlon, F.2    Bedrossian, D.3    Dagher, A.4
  • 25
    • 84862109667 scopus 로고    scopus 로고
    • Relationship of dopamine type 2 receptor binding potential with fasting neuroendocrine hormones and insulin sensitivity in human obesity
    • Dunn J.P., Kessler R.M., Feurer I.D., Volkow N.D., Patterson B.W., Ansari M.S., et al. Relationship of dopamine type 2 receptor binding potential with fasting neuroendocrine hormones and insulin sensitivity in human obesity. Diabetes Care 2012, 35:1105-1111.
    • (2012) Diabetes Care , vol.35 , pp. 1105-1111
    • Dunn, J.P.1    Kessler, R.M.2    Feurer, I.D.3    Volkow, N.D.4    Patterson, B.W.5    Ansari, M.S.6
  • 26
    • 84866478612 scopus 로고    scopus 로고
    • Neural Correlates to Food-Related Behavior in Normal-Weight and Overweight/Obese Participants
    • Ho A., Kennedy J., Dimitropoulos A. Neural Correlates to Food-Related Behavior in Normal-Weight and Overweight/Obese Participants. Plos One 2012, 7:1-9.
    • (2012) Plos One , vol.7 , pp. 1-9
    • Ho, A.1    Kennedy, J.2    Dimitropoulos, A.3
  • 27
    • 84883824312 scopus 로고    scopus 로고
    • Chronic stress exposure may affect the brain's response to high calorie food cues and predispose to obesogenic eating habits
    • Tryon M.S., Carter C.S., Decant R., Laugero K.D. Chronic stress exposure may affect the brain's response to high calorie food cues and predispose to obesogenic eating habits. Physiol Behav 2013, 120:233-242.
    • (2013) Physiol Behav , vol.120 , pp. 233-242
    • Tryon, M.S.1    Carter, C.S.2    Decant, R.3    Laugero, K.D.4
  • 28
    • 84873732148 scopus 로고    scopus 로고
    • Acute stress potentiates brain response to milkshake as a function of body weight and chronic stress
    • Rudenga K.J., Sinha R., Small D.M. Acute stress potentiates brain response to milkshake as a function of body weight and chronic stress. Int J Obes (Lond) 2013, 37:309-316.
    • (2013) Int J Obes (Lond) , vol.37 , pp. 309-316
    • Rudenga, K.J.1    Sinha, R.2    Small, D.M.3
  • 29
    • 79951948370 scopus 로고    scopus 로고
    • Dietary restraint violations influence reward responses in nucleus accumbens and amygdala
    • Demos K.E., Kelley W.M., Heatherton T.F. Dietary restraint violations influence reward responses in nucleus accumbens and amygdala. J Cogn Neurosci 2011, 23:1952-1963.
    • (2011) J Cogn Neurosci , vol.23 , pp. 1952-1963
    • Demos, K.E.1    Kelley, W.M.2    Heatherton, T.F.3
  • 30
    • 84895077083 scopus 로고    scopus 로고
    • Obese patients after gastric bypass surgery have lower brain-hedonic responses to food than after gastric banding
    • Scholtz S., Miras A.D., Chhina N., Prechtl C.G., Sleeth M.L., Daud N.M., et al. Obese patients after gastric bypass surgery have lower brain-hedonic responses to food than after gastric banding. Gut 2014, 63:891-902.
    • (2014) Gut , vol.63 , pp. 891-902
    • Scholtz, S.1    Miras, A.D.2    Chhina, N.3    Prechtl, C.G.4    Sleeth, M.L.5    Daud, N.M.6
  • 31
    • 84856303593 scopus 로고    scopus 로고
    • Amygdala response to sucrose consumption is inversely related to artificial sweetener use
    • Rudenga K.J., Phil M., Smal D.M. Amygdala response to sucrose consumption is inversely related to artificial sweetener use. Appetite 2012, 58:504-507.
    • (2012) Appetite , vol.58 , pp. 504-507
    • Rudenga, K.J.1    Phil, M.2    Smal, D.M.3
  • 33
    • 84881352304 scopus 로고    scopus 로고
    • Effect of insulin sensitivity on corticolimbic responses to food picture in women with polycystic ovary syndrome
    • Van Vugt D.A., Krzemien A., Alsaadi H., Palerme S., Reid R.L. Effect of insulin sensitivity on corticolimbic responses to food picture in women with polycystic ovary syndrome. Obesity (Silver Spring) 2013, 21:1215-1222.
    • (2013) Obesity (Silver Spring) , vol.21 , pp. 1215-1222
    • Van Vugt, D.A.1    Krzemien, A.2    Alsaadi, H.3    Palerme, S.4    Reid, R.L.5
  • 34
    • 0028215077 scopus 로고
    • Effect on food intake and body weight of lesion in and adjacent to posterodorsal amydala in rats
    • King B.M., Sam H., Arceneaux E.R., Kass J.M. Effect on food intake and body weight of lesion in and adjacent to posterodorsal amydala in rats. Physiol Behav 1994, 55:963-966.
    • (1994) Physiol Behav , vol.55 , pp. 963-966
    • King, B.M.1    Sam, H.2    Arceneaux, E.R.3    Kass, J.M.4
  • 35
    • 0029903886 scopus 로고    scopus 로고
    • Hyperinsulinemia in rats with obesity-inducing amydaloid lesions
    • King B.M., Cook J.T., Dallman M.F. Hyperinsulinemia in rats with obesity-inducing amydaloid lesions. Am J Physiol 1996, 271:1156-1159.
    • (1996) Am J Physiol , vol.271 , pp. 1156-1159
    • King, B.M.1    Cook, J.T.2    Dallman, M.F.3
  • 36
    • 33845873042 scopus 로고    scopus 로고
    • Brain regions responsible for the expression of conditioned taste aversion in rats
    • Yamamoto T. Brain regions responsible for the expression of conditioned taste aversion in rats. Chem Senses 2008, 32:105-109.
    • (2008) Chem Senses , vol.32 , pp. 105-109
    • Yamamoto, T.1
  • 37
    • 0015972086 scopus 로고
    • Lateral hypothalamic electrical stimulation: does it make animals hungry?
    • Wise R.A. Lateral hypothalamic electrical stimulation: does it make animals hungry?. Brain Res 1974, 67:187-209.
    • (1974) Brain Res , vol.67 , pp. 187-209
    • Wise, R.A.1
  • 38
    • 0033082380 scopus 로고    scopus 로고
    • From lesions to leptin: hypothalamic control of food intake and body weight
    • Elmquist J.K., Elias C.F., Saper C.B. From lesions to leptin: hypothalamic control of food intake and body weight. Neuron 1999, 22:221-232.
    • (1999) Neuron , vol.22 , pp. 221-232
    • Elmquist, J.K.1    Elias, C.F.2    Saper, C.B.3
  • 39
    • 1042286441 scopus 로고    scopus 로고
    • Ventral striatal control of appetitive motivation: role iningestive behavior and reward-related learning
    • Kelley A.E. Ventral striatal control of appetitive motivation: role iningestive behavior and reward-related learning. Neurosci Biobehav Rev 2004, 27:765-776.
    • (2004) Neurosci Biobehav Rev , vol.27 , pp. 765-776
    • Kelley, A.E.1
  • 40
    • 0036812537 scopus 로고    scopus 로고
    • Amygdalo-hypothalamic circuit allows learned cues to override satiety and promote eating
    • Petrovich G.D., Setlow B., Holland P.C., Gallagher M. Amygdalo-hypothalamic circuit allows learned cues to override satiety and promote eating. J Neurosci 2002, 22:8748-8753.
    • (2002) J Neurosci , vol.22 , pp. 8748-8753
    • Petrovich, G.D.1    Setlow, B.2    Holland, P.C.3    Gallagher, M.4
  • 41
    • 0032942045 scopus 로고    scopus 로고
    • Characterization of the neuroanatomical distribution of agouti related protein immunoreactivity in the rhesus monkey and the rat
    • Haskell-Luevano C., Chen P., Li C., Chang K., Smith M.S., Cameron J.L., et al. Characterization of the neuroanatomical distribution of agouti related protein immunoreactivity in the rhesus monkey and the rat. Endocrinology 1999, 140:1408-1415.
    • (1999) Endocrinology , vol.140 , pp. 1408-1415
    • Haskell-Luevano, C.1    Chen, P.2    Li, C.3    Chang, K.4    Smith, M.S.5    Cameron, J.L.6
  • 42
    • 0028134706 scopus 로고
    • Localization of melanocortin-4 receptor (MC4-R) in neuroendocrine and autonomic control circuits in the brain
    • Mountjov Kg Mortrud M.T., Low M.J., Simerly R.B., Cone R.D. Localization of melanocortin-4 receptor (MC4-R) in neuroendocrine and autonomic control circuits in the brain. Mol Endocrinol 1994, 8:1298-1308.
    • (1994) Mol Endocrinol , vol.8 , pp. 1298-1308
    • Mountjov Kg Mortrud, M.T.1    Low, M.J.2    Simerly, R.B.3    Cone, R.D.4
  • 43
    • 35348818238 scopus 로고    scopus 로고
    • Genetic dissection of neuronal pathways controlling energy homeostasis
    • Balthasar N. Genetic dissection of neuronal pathways controlling energy homeostasis. Obesity Silver Spring 2006, 14:222S-227S.
    • (2006) Obesity Silver Spring , vol.14 , pp. 222S-227S
    • Balthasar, N.1
  • 44
    • 27544450765 scopus 로고    scopus 로고
    • Divergence of melanocortin pathways in the control of food intake and energy expenditure
    • Balthasar N., Dalgaard L.T., Lee C.E., Yu J., Funahashi H., Williams T., et al. Divergence of melanocortin pathways in the control of food intake and energy expenditure. Cell 2005, 123:493-505.
    • (2005) Cell , vol.123 , pp. 493-505
    • Balthasar, N.1    Dalgaard, L.T.2    Lee, C.E.3    Yu, J.4    Funahashi, H.5    Williams, T.6
  • 45
    • 0038051071 scopus 로고    scopus 로고
    • Knockout studies defining different roles for melanocortin receptors in energy homeostasis
    • Butler A.A., Cone R.D. Knockout studies defining different roles for melanocortin receptors in energy homeostasis. Ann NY Acad Sci 2003, 994:240-245.
    • (2003) Ann NY Acad Sci , vol.994 , pp. 240-245
    • Butler, A.A.1    Cone, R.D.2
  • 46
    • 75449113614 scopus 로고    scopus 로고
    • Melanocortin activity in the amygdale controls appetite for dietary fat
    • Boghossian S., Park M., York D. Melanocortin activity in the amygdale controls appetite for dietary fat. Am J Physiol Regul Integr Comp Physiol 2010, 298:R385-R393.
    • (2010) Am J Physiol Regul Integr Comp Physiol , vol.298 , pp. R385-R393
    • Boghossian, S.1    Park, M.2    York, D.3
  • 47
    • 0037145737 scopus 로고    scopus 로고
    • Diet-induced obesity increases mu opioid receptor binding in specific regions of the rat brain
    • Smith S.L., Harrold J.A., Williams G. Diet-induced obesity increases mu opioid receptor binding in specific regions of the rat brain. Brain Res 2002, 25:215-222.
    • (2002) Brain Res , vol.25 , pp. 215-222
    • Smith, S.L.1    Harrold, J.A.2    Williams, G.3
  • 48
    • 70449644663 scopus 로고    scopus 로고
    • High-fat diets induce a rapid loss of the insulin anorectic response in the amygdala
    • Boghossian S., Lemmon K., Park M., York D. High-fat diets induce a rapid loss of the insulin anorectic response in the amygdala. Am J Physiol Regul Integr Comp Physiol 2009, 297:R1302-R1311.
    • (2009) Am J Physiol Regul Integr Comp Physiol , vol.297 , pp. R1302-R1311
    • Boghossian, S.1    Lemmon, K.2    Park, M.3    York, D.4
  • 49
    • 84887076229 scopus 로고    scopus 로고
    • Diet-induced obesity induces endoplasmic reticulum stress and insulin resistance in the amygdala of rats
    • Castro G., Areias C.M.F., Weissmann L., Quaresma P.G.F., Katashima C.K., Saad M.J.A., et al. Diet-induced obesity induces endoplasmic reticulum stress and insulin resistance in the amygdala of rats. FEBS Open Bio 2013, 3:443-449.
    • (2013) FEBS Open Bio , vol.3 , pp. 443-449
    • Castro, G.1    Areias, C.M.F.2    Weissmann, L.3    Quaresma, P.G.F.4    Katashima, C.K.5    Saad, M.J.A.6
  • 50
    • 84887255219 scopus 로고    scopus 로고
    • The effect of high fat diet and saturated acids on insulin signaling in the amygdala and hypothalamus of rats. Brain Res
    • Oh H, Boghossian S; York D; Park-York M. The effect of high fat diet and saturated acids on insulin signaling in the amygdala and hypothalamus of rats. Brain Res 2013;191-200.
    • (2013) , pp. 191-200
    • Oh, H.1    Boghossian S2    York, D3    Park-York, M.5
  • 52
  • 53
    • 27344431720 scopus 로고    scopus 로고
    • NPY/AgRP neurons are essential for feeding in adult mice but can be ablated in neonates
    • Luquet S., Perez F.A., Hnasko T.S., Palmiter R.D. NPY/AgRP neurons are essential for feeding in adult mice but can be ablated in neonates. Science 2005, 310:683-685.
    • (2005) Science , vol.310 , pp. 683-685
    • Luquet, S.1    Perez, F.A.2    Hnasko, T.S.3    Palmiter, R.D.4
  • 55
    • 0042567303 scopus 로고    scopus 로고
    • Comparative distribution of neuropeptide Y Y1 and Y5 receptors in the rat brain by using immunohistochemistry
    • Wolak M.L., De Joseph M.R., Cator A.D., Mokashi A.S., Brownfield M.S., Urban J.H. Comparative distribution of neuropeptide Y Y1 and Y5 receptors in the rat brain by using immunohistochemistry. J Comp Neurol 2003, 464:285-311.
    • (2003) J Comp Neurol , vol.464 , pp. 285-311
    • Wolak, M.L.1    De Joseph, M.R.2    Cator, A.D.3    Mokashi, A.S.4    Brownfield, M.S.5    Urban, J.H.6
  • 56
    • 0022364207 scopus 로고
    • The anatomy of neuropeptide- Y-containing neurons in rat brain
    • Ruggiero D.A., O'Donohue T.L. The anatomy of neuropeptide- Y-containing neurons in rat brain. Neuroscience 1985, 15:1159-1181.
    • (1985) Neuroscience , vol.15 , pp. 1159-1181
    • Ruggiero, D.A.1    O'Donohue, T.L.2
  • 57
    • 0025635929 scopus 로고
    • Organization of peptidergic and catecholaminergic efferents from the nucleus of the solitary tract to the rat amygdala
    • Zardetto-Smith A.M., Gray T.S. Organization of peptidergic and catecholaminergic efferents from the nucleus of the solitary tract to the rat amygdala. Brain Res Bull 1990, 25:875-887.
    • (1990) Brain Res Bull , vol.25 , pp. 875-887
    • Zardetto-Smith, A.M.1    Gray, T.S.2
  • 59
    • 0030780586 scopus 로고    scopus 로고
    • An autocrine progesterone positive feedback loop mediates oxytocin upregulation in bovine granulosa cells during luteinization
    • Lioutas C., Einspanier A., Kascheike B., Walther N., Ivell R. An autocrine progesterone positive feedback loop mediates oxytocin upregulation in bovine granulosa cells during luteinization. Endocrinology 1997, 138:5059-5062.
    • (1997) Endocrinology , vol.138 , pp. 5059-5062
    • Lioutas, C.1    Einspanier, A.2    Kascheike, B.3    Walther, N.4    Ivell, R.5
  • 60
    • 20044364733 scopus 로고    scopus 로고
    • Western diet modulates insulin signaling, c-Jun N-terminal kinase activity, and insulin receptor substrate-1ser307 phosphorylation in a tissue- specific fashion
    • Prada P.O., Zecchin H.G., Gasparetti A.L., Torsoni M.A., Ueno M., Hirata A.E., et al. Western diet modulates insulin signaling, c-Jun N-terminal kinase activity, and insulin receptor substrate-1ser307 phosphorylation in a tissue- specific fashion. Endocrinology 2005, 146:1576-1587.
    • (2005) Endocrinology , vol.146 , pp. 1576-1587
    • Prada, P.O.1    Zecchin, H.G.2    Gasparetti, A.L.3    Torsoni, M.A.4    Ueno, M.5    Hirata, A.E.6
  • 62
    • 57849115277 scopus 로고    scopus 로고
    • Endoplasmic reticulum stress plays a central role in development of leptin resistance
    • Ozcan L., Ergin A.S., Lu A., Chung J., Sarkar S., Nie D., et al. Endoplasmic reticulum stress plays a central role in development of leptin resistance. Cell Metab 2009, 9:35-51.
    • (2009) Cell Metab , vol.9 , pp. 35-51
    • Ozcan, L.1    Ergin, A.S.2    Lu, A.3    Chung, J.4    Sarkar, S.5    Nie, D.6
  • 63
    • 84879836874 scopus 로고    scopus 로고
    • PKCθ over expression in the central nucleus of the amygdala or hypothalamus as differential effects on energy balance and peripheral glucose homeostasis
    • Park-York M., Boghossian S., Hyoungil O.h., York D.A. PKCθ over expression in the central nucleus of the amygdala or hypothalamus as differential effects on energy balance and peripheral glucose homeostasis. Brain Res 2013, 1498:85-94.
    • (2013) Brain Res , vol.1498 , pp. 85-94
    • Park-York, M.1    Boghossian, S.2    Hyoungil, O.3    York, D.A.4
  • 64
    • 85027909820 scopus 로고    scopus 로고
    • PKCθ expression in the amygdala regulates insulin signaling, food intake and body weight
    • Park-York M., Boghossian S., Hyoungil O.h., York D.A. PKCθ expression in the amygdala regulates insulin signaling, food intake and body weight. Obesity 2012, 10:1-9.
    • (2012) Obesity , vol.10 , pp. 1-9
    • Park-York, M.1    Boghossian, S.2    Hyoungil, O.3    York, D.A.4
  • 65
    • 0028931724 scopus 로고
    • Increased adipose tissue expression of tumor necrosis factor-alpha in human obesity and insulin resistance
    • Hotamisligil G.S., Arner P., Caro J.F., Atkinson R.L., Spiegelman B.M. Increased adipose tissue expression of tumor necrosis factor-alpha in human obesity and insulin resistance. J Clin Invest 1995, 95:2409-2415.
    • (1995) J Clin Invest , vol.95 , pp. 2409-2415
    • Hotamisligil, G.S.1    Arner, P.2    Caro, J.F.3    Atkinson, R.L.4    Spiegelman, B.M.5
  • 68
    • 34250899722 scopus 로고    scopus 로고
    • Signal integration in the endoplasmic reticulum unfolded protein response
    • Ron D., Walter P. Signal integration in the endoplasmic reticulum unfolded protein response. Nat Rev Mol Cell Biol 2007, 8:519-529.
    • (2007) Nat Rev Mol Cell Biol , vol.8 , pp. 519-529
    • Ron, D.1    Walter, P.2
  • 69
    • 84855605795 scopus 로고    scopus 로고
    • Endoplasmic reticulum stress, obesity and diabetes
    • Cnop M., Foufelle F., Velloso L.A. Endoplasmic reticulum stress, obesity and diabetes. Trends Mol Med 2012, 18:59-68.
    • (2012) Trends Mol Med , vol.18 , pp. 59-68
    • Cnop, M.1    Foufelle, F.2    Velloso, L.A.3
  • 70
    • 84922054204 scopus 로고    scopus 로고
    • IL-6 and IL-10 anti-inflammatory activity links exercise to hypothalamic insulin and leptin sensitivity through IKKbeta and ER stress inhibition
    • Ropelle E.R., Flores M.B., Cintra D.E., Rocha G.Z., Pauli J.R., Morari J., et al. IL-6 and IL-10 anti-inflammatory activity links exercise to hypothalamic insulin and leptin sensitivity through IKKbeta and ER stress inhibition. PLoS Biol 2010, 8:1-20.
    • (2010) PLoS Biol , vol.8 , pp. 1-20
    • Ropelle, E.R.1    Flores, M.B.2    Cintra, D.E.3    Rocha, G.Z.4    Pauli, J.R.5    Morari, J.6
  • 71
    • 5644231992 scopus 로고    scopus 로고
    • Endoplasmic reticulum stress links obesity, insulin action, and type 2 diabetes
    • Ozcan U., Cao Q., Yilmaz E., Lee A.H., Iwakoshi N.N., Ozdelen E., et al. Endoplasmic reticulum stress links obesity, insulin action, and type 2 diabetes. Science 2004, 306:457-461.
    • (2004) Science , vol.306 , pp. 457-461
    • Ozcan, U.1    Cao, Q.2    Yilmaz, E.3    Lee, A.H.4    Iwakoshi, N.N.5    Ozdelen, E.6
  • 72
    • 70349507353 scopus 로고    scopus 로고
    • Central administration of an endoplasmic reticulum stress inducer inhibits the anorexigenic effects of leptin and insulin
    • Won J.C., Jang P.G., Namkoong C., Koh E.H., Kim S.K., Park J.Y., et al. Central administration of an endoplasmic reticulum stress inducer inhibits the anorexigenic effects of leptin and insulin. Obesity (Silver Spring) 2009, 17:1861-1865.
    • (2009) Obesity (Silver Spring) , vol.17 , pp. 1861-1865
    • Won, J.C.1    Jang, P.G.2    Namkoong, C.3    Koh, E.H.4    Kim, S.K.5    Park, J.Y.6
  • 73
    • 0035805629 scopus 로고    scopus 로고
    • Palmitate-induced apoptosis canoccur through a ceramide-independent pathway
    • Listenberger L.L., Ory D.S., Schaffer J.E. Palmitate-induced apoptosis canoccur through a ceramide-independent pathway. J Biol Chem 2001, 276:14890-14895.
    • (2001) J Biol Chem , vol.276 , pp. 14890-14895
    • Listenberger, L.L.1    Ory, D.S.2    Schaffer, J.E.3
  • 74
    • 79957605136 scopus 로고    scopus 로고
    • Aberrant lipid metabolism disrupts calcium homeostasis causing liver endoplasmic reticulum stress in obesity
    • Fu S., Yang L., Li P., Hofmann O., Dicker L. Aberrant lipid metabolism disrupts calcium homeostasis causing liver endoplasmic reticulum stress in obesity. Nature 2011, 473:528-531.
    • (2011) Nature , vol.473 , pp. 528-531
    • Fu, S.1    Yang, L.2    Li, P.3    Hofmann, O.4    Dicker, L.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.