SCD1 negatively regulates autophagy-induced cell death in human hepatocellular carcinoma through inactivation of the AMPK signaling pathway

Cancer Letters

Volumn 358, Issue 2, 2015, Pages 180-190

  Huang, Guang Ming ^a   Jiang, Qing Hu ^b   Cai, Can ^a   Qu, Mei ^a   Shen, Wei ^a  

^a THE SECOND AFFILIATED HOSPITAL OF CHONGQING MEDICAL UNIVERSITY   (China)

^b Department of Orthopaedic Surgery Hospital of Integrated Traditional and Western Medicine   (China)

Author keywords

AMPK; Autophagy; Hepatocellular carcinoma; SCD1

Indexed keywords

ACYL COENZYME A DESATURASE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; PROTEIN P62; LIGHT CHAIN 3, HUMAN; MICROTUBULE ASSOCIATED PROTEIN; P62 PROTEIN, HUMAN; RNA BINDING PROTEIN; SCD1 PROTEIN, HUMAN;

ADULT; APOPTOSIS; ARTICLE; AUTOPHAGY; CANCER PROGNOSIS; CANCER SURGERY; CANCER SURVIVAL; CELL DEATH; CELL VIABILITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; CORRELATIONAL STUDY; ENZYME ACTIVATION; ENZYME INACTIVATION; ENZYME INHIBITION; FEMALE; FOLLOW UP; GENE; GENE EXPRESSION REGULATION; HUMAN; HUMAN CELL; LC3 GENE; LIVER CELL CARCINOMA; MAJOR CLINICAL STUDY; MALE; OVERALL SURVIVAL; P62 GENE; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; UPREGULATION; AGED; CANCER GRADING; CANCER STAGING; CELL PROLIFERATION; CELL SURVIVAL; DRUG EFFECTS; GENETICS; LIVER TUMOR; METABOLISM; MIDDLE AGED; MORTALITY; PATHOLOGY; PROGNOSIS; TUMOR CELL LINE; TUMOR VOLUME;

ADULT; AGED; AMP-ACTIVATED PROTEIN KINASES; APOPTOSIS; AUTOPHAGY; CARCINOMA, HEPATOCELLULAR; CELL LINE, TUMOR; CELL PROLIFERATION; CELL SURVIVAL; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; LIVER NEOPLASMS; MALE; MICROTUBULE-ASSOCIATED PROTEINS; MIDDLE AGED; NEOPLASM GRADING; NEOPLASM STAGING; PROGNOSIS; RNA-BINDING PROTEINS; SIGNAL TRANSDUCTION; STEAROYL-COA DESATURASE; TUMOR BURDEN;

EID: 84921605764     PISSN: 03043835     EISSN: 18727980     Source Type: Journal    
DOI: 10.1016/j.canlet.2014.12.036     Document Type: Article

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