메뉴 건너뛰기




Volumn 12, Issue , 2012, Pages

Autophagy and apoptosis-related genes in chronic liver disease and hepatocellular carcinoma

Author keywords

Autophagy; B and C virus infection; Beclin 1; Hepatocellular carcinoma; Pro and anti apoptotic factors.

Indexed keywords

BECLIN 1; MESSENGER RNA; PROTEIN BAD; PROTEIN BAX; PROTEIN BCL 2; PROTEIN BCL XL;

EID: 84865323320     PISSN: None     EISSN: 1471230X     Source Type: Journal    
DOI: 10.1186/1471-230X-12-118     Document Type: Article
Times cited : (51)

References (41)
  • 1
    • 78649704325 scopus 로고    scopus 로고
    • Autophagy and metabolism
    • 10.1126/science.1193497, 3010857, 21127245
    • Rabinowitz JD, White E. Autophagy and metabolism. Science 2010, 330:1344-1348. 10.1126/science.1193497, 3010857, 21127245.
    • (2010) Science , vol.330 , pp. 1344-1348
    • Rabinowitz, J.D.1    White, E.2
  • 3
    • 69349094578 scopus 로고    scopus 로고
    • Role and regulation of autophagy in cancer
    • 10.1016/j.bbamcr.2008.12.013, 3155287, 19167434
    • Chen N, Karantza-Wadsworth V. Role and regulation of autophagy in cancer. Biochim Biophys Acta 2009, 1793:1516-1523. 10.1016/j.bbamcr.2008.12.013, 3155287, 19167434.
    • (2009) Biochim Biophys Acta , vol.1793 , pp. 1516-1523
    • Chen, N.1    Karantza-Wadsworth, V.2
  • 4
    • 0344142468 scopus 로고    scopus 로고
    • Cloning and genomic organization of beclin 1, a candidate tumor suppressor gene on chromosome 17q21
    • 10.1006/geno.1999.5851, 10395800
    • Aita VM, Liang XH, Murty VV, Pincus DL, Yu W, Cayanis E, Kalachikov S, Gilliam TC, Levine B. Cloning and genomic organization of beclin 1, a candidate tumor suppressor gene on chromosome 17q21. Genomics 1999, 59:59-65. 10.1006/geno.1999.5851, 10395800.
    • (1999) Genomics , vol.59 , pp. 59-65
    • Aita, V.M.1    Liang, X.H.2    Murty, V.V.3    Pincus, D.L.4    Yu, W.5    Cayanis, E.6    Kalachikov, S.7    Gilliam, T.C.8    Levine, B.9
  • 5
    • 0345166111 scopus 로고    scopus 로고
    • Beclin 1, an autophagy gene essential for early embryonic development, is a haploinsufficient tumor suppressor
    • 10.1073/pnas.2436255100, 299911, 14657337
    • Yue Z, Jin S, Yang C, Levine AJ, Heintz N. Beclin 1, an autophagy gene essential for early embryonic development, is a haploinsufficient tumor suppressor. Proc Natl Acad Sci U S A 2003, 100:15077-15082. 10.1073/pnas.2436255100, 299911, 14657337.
    • (2003) Proc Natl Acad Sci U S A , vol.100 , pp. 15077-15082
    • Yue, Z.1    Jin, S.2    Yang, C.3    Levine, A.J.4    Heintz, N.5
  • 7
    • 58149084586 scopus 로고    scopus 로고
    • Decreased expression of autophagy-related proteins in malignant epithelial ovarian cancer
    • Shen Y, Li DD, Wang LL, Deng R, Zhu XF. Decreased expression of autophagy-related proteins in malignant epithelial ovarian cancer. Autophagy 2008, 4:1067-1068.
    • (2008) Autophagy , vol.4 , pp. 1067-1068
    • Shen, Y.1    Li, D.D.2    Wang, L.L.3    Deng, R.4    Zhu, X.F.5
  • 8
    • 83055194636 scopus 로고    scopus 로고
    • Decreased Beclin-1 expression is correlated with the growth of the primary tumor in patients with squamous cell carcinoma and adenocarcinoma of the lung
    • Won KY, Kim GY, Lim SJ, Kim YW. Decreased Beclin-1 expression is correlated with the growth of the primary tumor in patients with squamous cell carcinoma and adenocarcinoma of the lung. Hum Pathol 2011, 43:62-68.
    • (2011) Hum Pathol , vol.43 , pp. 62-68
    • Won, K.Y.1    Kim, G.Y.2    Lim, S.J.3    Kim, Y.W.4
  • 9
    • 70349641918 scopus 로고    scopus 로고
    • Beclin-1 expression is a predictor of clinical outcome in patients with esophageal squamous cell carcinoma and correlated to hypoxia-inducible factor (HIF)-1alpha expression
    • 10.1007/s12253-008-9143-8, 2791489, 19130303
    • Chen Y, Lu Y, Lu C, Zhang L. Beclin-1 expression is a predictor of clinical outcome in patients with esophageal squamous cell carcinoma and correlated to hypoxia-inducible factor (HIF)-1alpha expression. Pathol Oncol Res 2009, 15:487-493. 10.1007/s12253-008-9143-8, 2791489, 19130303.
    • (2009) Pathol Oncol Res , vol.15 , pp. 487-493
    • Chen, Y.1    Lu, Y.2    Lu, C.3    Zhang, L.4
  • 10
    • 65249180744 scopus 로고    scopus 로고
    • The expression of beclin 1 is associated with favorable prognosis in stage IIIB colon cancers
    • 10.4161/auto.5.3.7491, 19066461
    • Li BX, Li CY, Peng RQ, Wu XJ, Wang HY, Wan DS, Zhu XF, Zhang XS. The expression of beclin 1 is associated with favorable prognosis in stage IIIB colon cancers. Autophagy 2009, 5:303-306. 10.4161/auto.5.3.7491, 19066461.
    • (2009) Autophagy , vol.5 , pp. 303-306
    • Li, B.X.1    Li, C.Y.2    Peng, R.Q.3    Wu, X.J.4    Wang, H.Y.5    Wan, D.S.6    Zhu, X.F.7    Zhang, X.S.8
  • 11
    • 37549063395 scopus 로고    scopus 로고
    • Expression of beclin-1, an autophagy-related protein, in gastric and colorectal cancers
    • 10.1111/j.1600-0463.2007.00858.x, 18184403
    • Ahn CH, Jeong EG, Lee JW, Kim MS, Kim SH, Kim SS, Yoo NJ, Lee SH. Expression of beclin-1, an autophagy-related protein, in gastric and colorectal cancers. APMIS 2007, 115:1344-1349. 10.1111/j.1600-0463.2007.00858.x, 18184403.
    • (2007) APMIS , vol.115 , pp. 1344-1349
    • Ahn, C.H.1    Jeong, E.G.2    Lee, J.W.3    Kim, M.S.4    Kim, S.H.5    Kim, S.S.6    Yoo, N.J.7    Lee, S.H.8
  • 12
    • 78751655392 scopus 로고    scopus 로고
    • Bcl-2 and Bcl-xL play important roles in the crosstalk between autophagy and apoptosis
    • 10.1111/j.1742-4658.2010.07965.x, 21182587
    • Zhou F, Yang Y, Xing D. Bcl-2 and Bcl-xL play important roles in the crosstalk between autophagy and apoptosis. FEBS J 2011, 278:403-413. 10.1111/j.1742-4658.2010.07965.x, 21182587.
    • (2011) FEBS J , vol.278 , pp. 403-413
    • Zhou, F.1    Yang, Y.2    Xing, D.3
  • 13
    • 76349098949 scopus 로고    scopus 로고
    • Crosstalk between apoptosis and autophagy within the Beclin 1 interactome
    • 10.1038/emboj.2009.377, 2830702, 20125189
    • Maiuri MC, Criollo A, Kroemer G. Crosstalk between apoptosis and autophagy within the Beclin 1 interactome. EMBO J 2010, 29:515-516. 10.1038/emboj.2009.377, 2830702, 20125189.
    • (2010) EMBO J , vol.29 , pp. 515-516
    • Maiuri, M.C.1    Criollo, A.2    Kroemer, G.3
  • 14
    • 68149139456 scopus 로고    scopus 로고
    • The autophagy effector Beclin 1: a novel BH3-only protein
    • 2731580, 19641499
    • Sinha S, Levine B. The autophagy effector Beclin 1: a novel BH3-only protein. Oncogene 2008, 27:S137-S148. 2731580, 19641499.
    • (2008) Oncogene , vol.27
    • Sinha, S.1    Levine, B.2
  • 15
    • 34547689505 scopus 로고    scopus 로고
    • Molecular basis of Bcl-xL's target recognition versatility revealed by the structure of Bcl-xL in complex with the BH3 domain of Beclin-1
    • 10.1016/j.jmb.2007.06.069, 17659302
    • Feng W, Huang S, Wu H, Zhang M. Molecular basis of Bcl-xL's target recognition versatility revealed by the structure of Bcl-xL in complex with the BH3 domain of Beclin-1. J Mol Biol 2007, 372:223-235. 10.1016/j.jmb.2007.06.069, 17659302.
    • (2007) J Mol Biol , vol.372 , pp. 223-235
    • Feng, W.1    Huang, S.2    Wu, H.3    Zhang, M.4
  • 16
    • 77955466663 scopus 로고    scopus 로고
    • Hepatocellular carcinoma: a global view
    • 10.1038/nrgastro.2010.100, 20628345
    • Yang JD, Roberts LR. Hepatocellular carcinoma: a global view. Nat Rev Gastroenterol Hepatol 2010, 7:448-458. 10.1038/nrgastro.2010.100, 20628345.
    • (2010) Nat Rev Gastroenterol Hepatol , vol.7 , pp. 448-458
    • Yang, J.D.1    Roberts, L.R.2
  • 18
    • 78651053628 scopus 로고
    • Primary carcinoma of the liver: a study of 100 cases among 48,900 necropsies
    • 10.1002/1097-0142(195405)7:3<462::AID-CNCR2820070308>3.0.CO;2-E, 13160935
    • Edmondson HA, Steiner PE. Primary carcinoma of the liver: a study of 100 cases among 48,900 necropsies. Cancer 1954, 7:462-503. 10.1002/1097-0142(195405)7:3<462::AID-CNCR2820070308>3.0.CO;2-E, 13160935.
    • (1954) Cancer , vol.7 , pp. 462-503
    • Edmondson, H.A.1    Steiner, P.E.2
  • 19
    • 0023277545 scopus 로고
    • Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction
    • Chomczynski P, Sacchi N. Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal Biochem 1987, 162:156-159.
    • (1987) Anal Biochem , vol.162 , pp. 156-159
    • Chomczynski, P.1    Sacchi, N.2
  • 20
    • 0034993341 scopus 로고    scopus 로고
    • Real-time reverse transcriptase-polymerase chain reaction (RT-PCR) for measurement of cytokine and growth factor mRNA expression with fluorogenic probes or SYBR Green I
    • 10.1046/j.1440-1711.2001.01002.x, 11380673
    • Yin JL, Shackel NA, Zekry A, McGuinness PH, Richards C, Putten KV, McCaughan GW, Eris JM, Bishop GA. Real-time reverse transcriptase-polymerase chain reaction (RT-PCR) for measurement of cytokine and growth factor mRNA expression with fluorogenic probes or SYBR Green I. Immunol Cell Biol 2001, 79:213-221. 10.1046/j.1440-1711.2001.01002.x, 11380673.
    • (2001) Immunol Cell Biol , vol.79 , pp. 213-221
    • Yin, J.L.1    Shackel, N.A.2    Zekry, A.3    McGuinness, P.H.4    Richards, C.5    Putten, K.V.6    McCaughan, G.W.7    Eris, J.M.8    Bishop, G.A.9
  • 21
    • 4444337502 scopus 로고    scopus 로고
    • Mathematics of quantitative kinetic PCR and the application of standard curves
    • 10.1093/nar/gng093, 169985, 12907745
    • Rutledge RG, Côté C. Mathematics of quantitative kinetic PCR and the application of standard curves. Nucleic Acids Res 2003, 31:e93. 10.1093/nar/gng093, 169985, 12907745.
    • (2003) Nucleic Acids Res , vol.31
    • Rutledge, R.G.1    Côté, C.2
  • 22
    • 65249135974 scopus 로고    scopus 로고
    • Prognostic significance of Beclin 1-dependent apoptotic activity in hepatocellular carcinoma
    • 10.4161/auto.5.3.7658, 19145109
    • Shi YH, Ding ZB, Zhou J, Qiu SJ, Fan J. Prognostic significance of Beclin 1-dependent apoptotic activity in hepatocellular carcinoma. Autophagy 2009, 5:380-382. 10.4161/auto.5.3.7658, 19145109.
    • (2009) Autophagy , vol.5 , pp. 380-382
    • Shi, Y.H.1    Ding, Z.B.2    Zhou, J.3    Qiu, S.J.4    Fan, J.5
  • 23
    • 1542345027 scopus 로고    scopus 로고
    • Genes encoding Pir51, Beclin 1, RbAp48 and aldolase b are up or down-regulated in human primary hepatocellular carcinoma
    • Song H, Xia SL, Liao C, Li YL, Wang YF, Li TP, Zhao MJ. Genes encoding Pir51, Beclin 1, RbAp48 and aldolase b are up or down-regulated in human primary hepatocellular carcinoma. World J Gastroenterol 2004, 10:509-513.
    • (2004) World J Gastroenterol , vol.10 , pp. 509-513
    • Song, H.1    Xia, S.L.2    Liao, C.3    Li, Y.L.4    Wang, Y.F.5    Li, T.P.6    Zhao, M.J.7
  • 25
    • 0027787534 scopus 로고
    • Reduced autophagic activity in primary rat hepatocellular carcinoma and ascites hepatoma cells
    • 10.1093/carcin/14.12.2501, 8269618
    • Kisen GO, Tessitore L, Costelli P, Gordon PB, Schwarze PE, Baccino FM, Seglen PO. Reduced autophagic activity in primary rat hepatocellular carcinoma and ascites hepatoma cells. Carcinogenesis 1993, 14:2501-2505. 10.1093/carcin/14.12.2501, 8269618.
    • (1993) Carcinogenesis , vol.14 , pp. 2501-2505
    • Kisen, G.O.1    Tessitore, L.2    Costelli, P.3    Gordon, P.B.4    Schwarze, P.E.5    Baccino, F.M.6    Seglen, P.O.7
  • 26
    • 69549135689 scopus 로고    scopus 로고
    • The autophagy machinery is required to initiate hepatitis C virus replication
    • 10.1073/pnas.0907344106, 2729017, 19666601
    • Dreux M, Gastaminza P, Wieland SF, Chisari FV. The autophagy machinery is required to initiate hepatitis C virus replication. Proc Natl Acad Sci U S A 2009, 106:14046-14051. 10.1073/pnas.0907344106, 2729017, 19666601.
    • (2009) Proc Natl Acad Sci U S A , vol.106 , pp. 14046-14051
    • Dreux, M.1    Gastaminza, P.2    Wieland, S.F.3    Chisari, F.V.4
  • 28
    • 39749116856 scopus 로고    scopus 로고
    • Hepatitis C virus genotype 1a growth and induction of autophagy
    • 10.1128/JVI.02093-07, 2258951, 18077704
    • Ait-Goughoulte M, Kanda T, Meyer K, Ryerse JS, Ray RB, Ray R. Hepatitis C virus genotype 1a growth and induction of autophagy. J Virol 2008, 82:2241-2249. 10.1128/JVI.02093-07, 2258951, 18077704.
    • (2008) J Virol , vol.82 , pp. 2241-2249
    • Ait-Goughoulte, M.1    Kanda, T.2    Meyer, K.3    Ryerse, J.S.4    Ray, R.B.5    Ray, R.6
  • 29
    • 68149107692 scopus 로고    scopus 로고
    • BAD: undertaker by night, candyman by day
    • Danial NN. BAD: undertaker by night, candyman by day. Oncogene 2008, 27:S53-70.
    • (2008) Oncogene , vol.27
    • Danial, N.N.1
  • 30
    • 0035848736 scopus 로고    scopus 로고
    • Endoplasmic reticulum localized Bcl-2 prevents apoptosis when redistribution of cytochrome c is a late event
    • Annis MG, Zanzami N, Zhu W, Penn LZ, Kroemer G, Leber B, Andrews DW. Endoplasmic reticulum localized Bcl-2 prevents apoptosis when redistribution of cytochrome c is a late event. Oncogene 2001, 12:1939-1952.
    • (2001) Oncogene , vol.12 , pp. 1939-1952
    • Annis, M.G.1    Zanzami, N.2    Zhu, W.3    Penn, L.Z.4    Kroemer, G.5    Leber, B.6    Andrews, D.W.7
  • 32
    • 33748668261 scopus 로고    scopus 로고
    • Bcl-xL is qualitatively different from and ten time more effective than Bcl-2 when expressed in a breast cancer cell line
    • 10.1186/1471-2407-6-213, 1560389, 16928273
    • Fiebig AA, Zhu W, Hollerbach C, Leber B, Andrews D. Bcl-xL is qualitatively different from and ten time more effective than Bcl-2 when expressed in a breast cancer cell line. BMC Cancer 2006, 6:213. 10.1186/1471-2407-6-213, 1560389, 16928273.
    • (2006) BMC Cancer , vol.6 , pp. 213
    • Fiebig, A.A.1    Zhu, W.2    Hollerbach, C.3    Leber, B.4    Andrews, D.5
  • 35
    • 77649289360 scopus 로고    scopus 로고
    • Differential dependence on Beclin 1 for the regulation of pro-survival autophagy by Bcl-2 and Bcl-xL in HCT116 colorectal cancer cells
    • 10.1371/journal.pone.0008755, 2807451, 20090905
    • Priault M, Hue E, Marhuenda F, Pilet P, Oliver L, Vallette FM. Differential dependence on Beclin 1 for the regulation of pro-survival autophagy by Bcl-2 and Bcl-xL in HCT116 colorectal cancer cells. PLoS One 2010, 5:e8755. 10.1371/journal.pone.0008755, 2807451, 20090905.
    • (2010) PLoS One , vol.5
    • Priault, M.1    Hue, E.2    Marhuenda, F.3    Pilet, P.4    Oliver, L.5    Vallette, F.M.6
  • 36
    • 27744494813 scopus 로고    scopus 로고
    • Human hepatitis B virus X protein induces apoptosis in HepG2 cells: role of BH3 domain
    • 10.1016/j.bbrc.2005.10.117, 16274670
    • Lu YW, Chen WN. Human hepatitis B virus X protein induces apoptosis in HepG2 cells: role of BH3 domain. Biochem Biophys Res Commun 2005, 338:1551-1556. 10.1016/j.bbrc.2005.10.117, 16274670.
    • (2005) Biochem Biophys Res Commun , vol.338 , pp. 1551-1556
    • Lu, Y.W.1    Chen, W.N.2
  • 37
    • 58949098335 scopus 로고    scopus 로고
    • Hepatitis B virus X protein sensitizes cells to starvation-induced autophagy via up-regulation of beclin 1 expression
    • 10.1002/hep.22581, 19065679
    • Tang H, Da L, Mao Y, Li Y, Li D, Xu Z, Li F, Wang Y, Tiollais P, Li T, Zhao M. Hepatitis B virus X protein sensitizes cells to starvation-induced autophagy via up-regulation of beclin 1 expression. Hepatology 2009, 49:60-71. 10.1002/hep.22581, 19065679.
    • (2009) Hepatology , vol.49 , pp. 60-71
    • Tang, H.1    Da, L.2    Mao, Y.3    Li, Y.4    Li, D.5    Xu, Z.6    Li, F.7    Wang, Y.8    Tiollais, P.9    Li, T.10    Zhao, M.11
  • 38
    • 0037810844 scopus 로고    scopus 로고
    • Bax and Bak can localize to the endoplasmic reticulum to initiate apoptosis
    • 10.1083/jcb.200302084, 2172724, 12847083
    • Zong WX, Li C, Hatzivassiliou G, Lindsten T, Yu QC, Yuan J, Thompson CB. Bax and Bak can localize to the endoplasmic reticulum to initiate apoptosis. J Cell Biol 2003, 162:59-69. 10.1083/jcb.200302084, 2172724, 12847083.
    • (2003) J Cell Biol , vol.162 , pp. 59-69
    • Zong, W.X.1    Li, C.2    Hatzivassiliou, G.3    Lindsten, T.4    Yu, Q.C.5    Yuan, J.6    Thompson, C.B.7
  • 40
    • 44849094280 scopus 로고    scopus 로고
    • Fas/FasL system, IL-1beta expression and apoptosis in chronic HBV and HCV liver disease
    • 10.1111/j.1365-2893.2008.00974.x, 18331250
    • Bortolami M, Kotsafti A, Cardin R, Farinati F. Fas/FasL system, IL-1beta expression and apoptosis in chronic HBV and HCV liver disease. J Viral Hepat 2008, 15:515-522. 10.1111/j.1365-2893.2008.00974.x, 18331250.
    • (2008) J Viral Hepat , vol.15 , pp. 515-522
    • Bortolami, M.1    Kotsafti, A.2    Cardin, R.3    Farinati, F.4
  • 41
    • 12244250729 scopus 로고    scopus 로고
    • Cytokine, infiltrating macrophage and T cell-mediated response to development of primary and secondary human liver cancer
    • 10.1016/S1590-8658(02)80073-1, 12546515
    • Bortolami M, Venturi C, Giacomelli L, Scalerta R, Bacchetti S, Marino F, Floreani A, Lise M, Naccarato R, Farinati F. Cytokine, infiltrating macrophage and T cell-mediated response to development of primary and secondary human liver cancer. Dig Liver Dis 2002, 34:794-801. 10.1016/S1590-8658(02)80073-1, 12546515.
    • (2002) Dig Liver Dis , vol.34 , pp. 794-801
    • Bortolami, M.1    Venturi, C.2    Giacomelli, L.3    Scalerta, R.4    Bacchetti, S.5    Marino, F.6    Floreani, A.7    Lise, M.8    Naccarato, R.9    Farinati, F.10


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.