Inhibition of p53 increases chemosensitivity to 5-FU in nutrient-deprived hepatocarcinoma cells by suppressing autophagy

Cancer Letters

Volumn 346, Issue 2, 2014, Pages 278-284

  Guo, Xian ling ^a,b   Hu, Fei ^a,c   Zhang, Shan shan ^a   Zhao, Qiu dong ^a   Zong, Chen ^a   Ye, Fei ^a   Guo, Shi wei ^a   Zhang, Jian wei ^a   Li, Rong ^a   Wu, Meng chao ^a   Wei, Li xin ^a  

^a SECOND MILITARY MEDICAL UNIVERSITY   (China)

^b Hang Zhou Sanitarium of Navy   (China)

^c TENTH PEOPLE S HOSPITAL OF TONGJI UNIVERSITY   (China)

Author keywords

5FU; Autophagy; Hepatocarcinoma; Nutrient deprivation; P53

Indexed keywords

FLUOROURACIL; PIFITHRIN ALPHA; PROTEIN P53; REACTIVE OXYGEN METABOLITE; SMALL INTERFERING RNA; ANTINEOPLASTIC ANTIMETABOLITE; BENZOTHIAZOLE DERIVATIVE; PIFITHRIN; TOLUENE; TP53 PROTEIN, HUMAN;

APOPTOSIS; ARTICLE; AUTOPHAGY; CANCER CELL; CELL SURVIVAL; CONTROLLED STUDY; DRUG SENSITIVITY; HUMAN; HUMAN CELL; LIVER CELL CARCINOMA; MITOCHONDRION; NUTRIENT LIMITATION; PRIORITY JOURNAL; ANALOGS AND DERIVATIVES; ANTAGONISTS AND INHIBITORS; CARCINOMA, HEPATOCELLULAR; DRUG EFFECTS; DRUG POTENTIATION; HEPG2 CELL LINE; LIVER MITOCHONDRION; LIVER NEOPLASMS; METABOLISM; PATHOLOGY; TUMOR CELL LINE;

ANTIMETABOLITES, ANTINEOPLASTIC; APOPTOSIS; AUTOPHAGY; BENZOTHIAZOLES; CARCINOMA, HEPATOCELLULAR; CELL LINE, TUMOR; DRUG SYNERGISM; FLUOROURACIL; HEP G2 CELLS; HUMANS; LIVER NEOPLASMS; MITOCHONDRIA, LIVER; REACTIVE OXYGEN SPECIES; TOLUENE; TUMOR SUPPRESSOR PROTEIN P53;

EID: 84896116926     PISSN: 03043835     EISSN: 18727980     Source Type: Journal    
DOI: 10.1016/j.canlet.2014.01.011     Document Type: Article

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