Autophagy inhibition improves the efficacy of curcumin/temozolomide combination therapy in glioblastomas

Cancer Letters

Volumn 358, Issue 2, 2015, Pages 220-231

  Zanotto Filho, Alfeu ^a   Braganhol, Elizandra ^b   Klafke, Karina ^a   Figueiró, Fabrício ^a   Terra, Sílvia Resende ^a   Paludo, Francis Jackson ^a   Morrone, Maurílio ^a   Bristot, Ivi Juliana ^a   Battastini, Ana Maria ^a   Forcelini, Cassiano Mateus ^c   Bishop, Alexander James Roy ^d,e   Gelain, Daniel Pens ^a   Moreira, José Cláudio Fonseca ^a  

^a FEDERAL UNIVERSITY OF RIO GRANDE DO SUL   (Brazil)

^b UNIVERSIDADE FEDERAL DE CIÊNCIAS DA SAÚDE DE PORTO ALEGRE   (Brazil)

^c UNIVERSITY OF PASSO FUNDO   (Brazil)

^d UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT SAN ANTONIO   (United States)

^e Mays Cancer Center at UT Health San Antonio   (United States)

Author keywords

Apoptosis; Autophagy; Curcumin; ERK1 2; Temozolomide

Indexed keywords

3 METHYL ADENINE; ATR PROTEIN; AUTOPHAGY RELATED 7 PROTEIN; CHLOROQUINE; CURCUMIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE P38; PEPTIDES AND PROTEINS; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN MUTS; RESVERATROL; STAT3 PROTEIN; STRESS ACTIVATED PROTEIN KINASE; TEMOZOLOMIDE; UNCLASSIFIED DRUG; DACARBAZINE; MITOGEN ACTIVATED PROTEIN KINASE 1;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; AUTOPHAGY; AUTOPHAGY INHIBITION; BLOOD BRAIN BARRIER; CANCER COMBINATION CHEMOTHERAPY; CANCER INHIBITION; CANCER SURVIVAL; CONTROLLED STUDY; DNA DAMAGE; DRUG CYTOTOXICITY; DRUG EFFECT; DRUG EFFICACY; DRUG INDICATION; DRUG POTENTIATION; G2 PHASE CELL CYCLE CHECKPOINT; GLIOBLASTOMA; HUMAN; HUMAN CELL; HUMAN TISSUE; IN VITRO STUDY; IN VIVO STUDY; LONG TERM SURVIVAL; MALE; NONHUMAN; OUTCOME ASSESSMENT; RAT; SIGNAL TRANSDUCTION; ANALOGS AND DERIVATIVES; ANIMAL; BRAIN NEOPLASMS; CELL CYCLE CHECKPOINT; CELL SURVIVAL; DOSE RESPONSE; DRUG EFFECTS; METABOLISM; TUMOR CELL LINE;

ANIMALS; APOPTOSIS; AUTOPHAGY; BRAIN NEOPLASMS; CELL CYCLE CHECKPOINTS; CELL LINE, TUMOR; CELL SURVIVAL; CURCUMIN; DACARBAZINE; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG SYNERGISM; GLIOBLASTOMA; HUMANS; MALE; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; RATS;

EID: 84921553879     PISSN: 03043835     EISSN: 18727980     Source Type: Journal    
DOI: 10.1016/j.canlet.2014.12.044     Document Type: Article

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