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Volumn 194, Issue 3, 2015, Pages 1131-1140

Diverse roles for T-bet in the effector responses required for resistance to infection

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA2 INTEGRIN; CHEMOKINE RECEPTOR CXCR3; GAMMA INTERFERON; INTERLEUKIN 2; KLRG 1 PROTEIN; LY6C PROTEIN; LYMPHOCYTE FUNCTION ASSOCIATED ANTIGEN 1; T LYMPHOCYTE ANTIGEN; TRANSCRIPTION FACTOR T BET; UNCLASSIFIED DRUG; T BOX TRANSCRIPTION FACTOR; T-BOX TRANSCRIPTION FACTOR TBX21;

EID: 84921456080     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1401617     Document Type: Article
Times cited : (40)

References (72)
  • 1
    • 0034677646 scopus 로고    scopus 로고
    • A novel transcription factor, T-bet, directs Th1 lineage commitment
    • Szabo, S. J., S. T. Kim, G. L. Costa, X. Zhang, C. G. Fathman, and L. H. Glimcher. 2000. A novel transcription factor, T-bet, directs Th1 lineage commitment. Cell 100: 655-669.
    • (2000) Cell , vol.100 , pp. 655-669
    • Szabo, S.J.1    Kim, S.T.2    Costa, G.L.3    Zhang, X.4    Fathman, C.G.5    Glimcher, L.H.6
  • 2
    • 0037059462 scopus 로고    scopus 로고
    • Distinct effects of T-bet in TH1 lineage commitment and IFN-gamma production in CD4 and CD8 T cells
    • Szabo, S. J., B. M. Sullivan, C. Stemmann, A. R. Satoskar, B. P. Sleckman, and L. H. Glimcher. 2002. Distinct effects of T-bet in TH1 lineage commitment and IFN-gamma production in CD4 and CD8 T cells. Science 295: 338-342.
    • (2002) Science , vol.295 , pp. 338-342
    • Szabo, S.J.1    Sullivan, B.M.2    Stemmann, C.3    Satoskar, A.R.4    Sleckman, B.P.5    Glimcher, L.H.6
  • 4
    • 24944452197 scopus 로고    scopus 로고
    • The adjuvant activity of CpG DNA requires T-bet expression in dendritic cells
    • Lugo-Villarino, G., S. Ito, D. M. Klinman, and L. H. Glimcher. 2005. The adjuvant activity of CpG DNA requires T-bet expression in dendritic cells. Proc. Natl. Acad. Sci. USA 102: 13248-13253.
    • (2005) Proc. Natl. Acad. Sci. USA , vol.102 , pp. 13248-13253
    • Lugo-Villarino, G.1    Ito, S.2    Klinman, D.M.3    Glimcher, L.H.4
  • 7
    • 2442509626 scopus 로고    scopus 로고
    • T-bet controls autoaggressive CD8 lymphocyte responses in type 1 diabetes
    • Juedes, A. E., E. Rodrigo, L. Togher, L. H. Glimcher, and M. G. von Herrath. 2004. T-bet controls autoaggressive CD8 lymphocyte responses in type 1 diabetes. J. Exp. Med. 199: 1153-1162.
    • (2004) J. Exp. Med. , vol.199 , pp. 1153-1162
    • Juedes, A.E.1    Rodrigo, E.2    Togher, L.3    Glimcher, L.H.4    Von Herrath, M.G.5
  • 10
    • 84862777436 scopus 로고    scopus 로고
    • The transcription factors T-bet and Eomes control key checkpoints of natural killer cell maturation
    • Gordon, S. M., J. Chaix, L. J. Rupp, J. Wu, S. Madera, J. C. Sun, T. Lindsten, and S. L. Reiner. 2012. The transcription factors T-bet and Eomes control key checkpoints of natural killer cell maturation. Immunity 36: 55-67.
    • (2012) Immunity , vol.36 , pp. 55-67
    • Gordon, S.M.1    Chaix, J.2    Rupp, L.J.3    Wu, J.4    Madera, S.5    Sun, J.C.6    Lindsten, T.7    Reiner, S.L.8
  • 11
    • 33748174156 scopus 로고    scopus 로고
    • T-bet is a critical determinant in the instability of the IL-17-secreting T-helper phenotype
    • Mathur, A. N., H. C. Chang, D. G. Zisoulis, R. Kapur, M. L. Belladonna, G. S. Kansas, and M. H. Kaplan. 2006. T-bet is a critical determinant in the instability of the IL-17-secreting T-helper phenotype. Blood 108: 1595-1601.
    • (2006) Blood , vol.108 , pp. 1595-1601
    • Mathur, A.N.1    Chang, H.C.2    Zisoulis, D.G.3    Kapur, R.4    Belladonna, M.L.5    Kansas, G.S.6    Kaplan, M.H.7
  • 13
    • 25444439804 scopus 로고    scopus 로고
    • Expression of T-bet by CD4 T cells is essential for resistance to Salmonella infection
    • Ravindran, R., J. Foley, T. Stoklasek, L. H. Glimcher, and S. J. McSorley. 2005. Expression of T-bet by CD4 T cells is essential for resistance to Salmonella infection. J. Immunol. 175: 4603-4610.
    • (2005) J. Immunol. , vol.175 , pp. 4603-4610
    • Ravindran, R.1    Foley, J.2    Stoklasek, T.3    Glimcher, L.H.4    McSorley, S.J.5
  • 14
    • 25444482624 scopus 로고    scopus 로고
    • Increased susceptibility of mice lacking T-bet to infection with Mycobacterium tuberculosis correlates with increased IL-10 and decreased IFN-gamma production
    • Sullivan, B. M., O. Jobe, V. Lazarevic, K. Vasquez, R. Bronson, L. H. Glimcher, and I. Kramnik. 2005. Increased susceptibility of mice lacking T-bet to infection with Mycobacterium tuberculosis correlates with increased IL-10 and decreased IFN-gamma production. J. Immunol. 175: 4593-4602.
    • (2005) J. Immunol. , vol.175 , pp. 4593-4602
    • Sullivan, B.M.1    Jobe, O.2    Lazarevic, V.3    Vasquez, K.4    Bronson, R.5    Glimcher, L.H.6    Kramnik, I.7
  • 15
    • 18744373400 scopus 로고    scopus 로고
    • Protective immunity to genital herpes simplex [correction of simpex] virus type 2 infection is mediated by T-bet
    • Svensson, A., I. Nordström, J. B. Sun, and K. Eriksson. 2005. Protective immunity to genital herpes simplex [correction of simpex] virus type 2 infection is mediated by T-bet. J. Immunol. 174: 6266-6273.
    • (2005) J. Immunol. , vol.174 , pp. 6266-6273
    • Svensson, A.1    Nordström, I.2    Sun, J.B.3    Eriksson, K.4
  • 16
    • 8444242090 scopus 로고    scopus 로고
    • Cutting edge: Immunity and IFN-gamma production during Listeria monocytogenes infection in the absence of T-bet
    • Way, S. S., and C. B. Wilson. 2004. Cutting edge: immunity and IFN-gamma production during Listeria monocytogenes infection in the absence of T-bet. J. Immunol. 173: 5918-5922.
    • (2004) J. Immunol. , vol.173 , pp. 5918-5922
    • Way, S.S.1    Wilson, C.B.2
  • 18
    • 0026021838 scopus 로고
    • Synergistic role of CD4+ and CD8+ T lymphocytes in IFN-gamma production and protective immunity induced by an attenuated Toxoplasma gondii vaccine
    • Gazzinelli, R. T., F. T. Hakim, S. Hieny, G. M. Shearer, and A. Sher. 1991. Synergistic role of CD4+ and CD8+ T lymphocytes in IFN-gamma production and protective immunity induced by an attenuated Toxoplasma gondii vaccine. J. Immunol. 146: 286-292.
    • (1991) J. Immunol. , vol.146 , pp. 286-292
    • Gazzinelli, R.T.1    Hakim, F.T.2    Hieny, S.3    Shearer, G.M.4    Sher, A.5
  • 19
    • 0028348030 scopus 로고
    • Interleukin-12 enhances murine survival against acute toxoplasmosis
    • Khan, I. A., T. Matsuura, and L. H. Kasper. 1994. Interleukin-12 enhances murine survival against acute toxoplasmosis. Infect. Immun. 62: 1639-1642.
    • (1994) Infect. Immun. , vol.62 , pp. 1639-1642
    • Khan, I.A.1    Matsuura, T.2    Kasper, L.H.3
  • 20
    • 0042520922 scopus 로고    scopus 로고
    • Induction and regulation of IL-12-dependent host resistance to Toxoplasma gondii
    • Sher, A., C. Collazzo, C. Scanga, D. Jankovic, G. Yap, and J. Aliberti. 2003. Induction and regulation of IL-12-dependent host resistance to Toxoplasma gondii. Immunol. Res. 27: 521-528.
    • (2003) Immunol. Res. , vol.27 , pp. 521-528
    • Sher, A.1    Collazzo, C.2    Scanga, C.3    Jankovic, D.4    Yap, G.5    Aliberti, J.6
  • 21
    • 0346103720 scopus 로고    scopus 로고
    • STAT1 plays a critical role in the regulation of antimicrobial effector mechanisms, but not in the development of Th1-type responses during toxoplasmosis
    • Lieberman, L. A., M. Banica, S. L. Reiner, and C. A. Hunter. 2004. STAT1 plays a critical role in the regulation of antimicrobial effector mechanisms, but not in the development of Th1-type responses during toxoplasmosis. J. Immunol. 172: 457-463.
    • (2004) J. Immunol. , vol.172 , pp. 457-463
    • Lieberman, L.A.1    Banica, M.2    Reiner, S.L.3    Hunter, C.A.4
  • 22
    • 84867827632 scopus 로고    scopus 로고
    • The transcription factor T-bet is induced by multiple pathways and prevents an endogenous Th2 cell program during Th1 cell responses
    • Zhu, J., D. Jankovic, A. J. Oler, G. Wei, S. Sharma, G. Hu, L. Guo, R. Yagi, H. Yamane, G. Punkosdy, et al. 2012. The transcription factor T-bet is induced by multiple pathways and prevents an endogenous Th2 cell program during Th1 cell responses. Immunity. 37: 660-673.
    • (2012) Immunity , vol.37 , pp. 660-673
    • Zhu, J.1    Jankovic, D.2    Oler, A.J.3    Wei, G.4    Sharma, S.5    Hu, G.6    Guo, L.7    Yagi, R.8    Yamane, H.9    Punkosdy, G.10
  • 23
    • 34047256441 scopus 로고    scopus 로고
    • IRG proteins: Key mediators of interferon-regulated host resistance to intracellular pathogens
    • Taylor, G. A. 2007. IRG proteins: key mediators of interferon-regulated host resistance to intracellular pathogens. Cell. Microbiol. 9: 1099-1107.
    • (2007) Cell. Microbiol. , vol.9 , pp. 1099-1107
    • Taylor, G.A.1
  • 24
    • 84860258296 scopus 로고    scopus 로고
    • Interferon-inducible effector mechanisms in cell-autonomous immunity
    • MacMicking, J. D. 2012. Interferon-inducible effector mechanisms in cell-autonomous immunity. Nat. Rev. Immunol. 12: 367-382.
    • (2012) Nat. Rev. Immunol. , vol.12 , pp. 367-382
    • MacMicking, J.D.1
  • 25
    • 0020510450 scopus 로고
    • Augmentation of NK cell activity by soluble and particulate fractions of Toxoplasma gondii
    • Hauser, W. E., Jr., S. D. Sharma, and J. S. Remington. 1983. Augmentation of NK cell activity by soluble and particulate fractions of Toxoplasma gondii. J. Immunol. 131: 458-463.
    • (1983) J. Immunol. , vol.131 , pp. 458-463
    • Hauser, W.E.1    Sharma, S.D.2    Remington, J.S.3
  • 26
    • 7444272595 scopus 로고    scopus 로고
    • IL-10 is not required to prevent immune hyperactivity during memory responses to Toxoplasma gondii
    • Wille, U., M. Nishi, L. Lieberman, E. H. Wilson, D. S. Roos, and C. A. Hunter. 2004. IL-10 is not required to prevent immune hyperactivity during memory responses to Toxoplasma gondii. Parasite Immunol. 26: 229-236.
    • (2004) Parasite Immunol. , vol.26 , pp. 229-236
    • Wille, U.1    Nishi, M.2    Lieberman, L.3    Wilson, E.H.4    Roos, D.S.5    Hunter, C.A.6
  • 27
    • 79251515158 scopus 로고    scopus 로고
    • SPICE: Exploration and analysis of post-cytometric complex multivariate datasets
    • Roederer, M., J. L. Nozzi, and M. C. Nason. 2011. SPICE: exploration and analysis of post-cytometric complex multivariate datasets. Cytometry A 79: 167-174.
    • (2011) Cytometry A , vol.79 , pp. 167-174
    • Roederer, M.1    Nozzi, J.L.2    Nason, M.C.3
  • 28
    • 34548027000 scopus 로고    scopus 로고
    • Inflammation directs memory precursor and short-lived effector CD8(+) T cell fates via the graded expression of T-bet transcription factor
    • Joshi, N. S., W. Cui, A. Chandele, H. K. Lee, D. R. Urso, J. Hagman, L. Gapin, and S. M. Kaech. 2007. Inflammation directs memory precursor and short-lived effector CD8(+) T cell fates via the graded expression of T-bet transcription factor. Immunity 27: 281-295.
    • (2007) Immunity , vol.27 , pp. 281-295
    • Joshi, N.S.1    Cui, W.2    Chandele, A.3    Lee, H.K.4    Urso, D.R.5    Hagman, J.6    Gapin, L.7    Kaech, S.M.8
  • 29
    • 44449145582 scopus 로고    scopus 로고
    • IL-12 signaling drives CD8+ T cell IFN-gamma production and differentiation of KLRG1+ effector subpopulations during Toxoplasma gondii Infection
    • Wilson, D. C., S. Matthews, and G. S. Yap. 2008. IL-12 signaling drives CD8+ T cell IFN-gamma production and differentiation of KLRG1+ effector subpopulations during Toxoplasma gondii Infection. J. Immunol. 180: 5935-5945.
    • (2008) J. Immunol. , vol.180 , pp. 5935-5945
    • Wilson, D.C.1    Matthews, S.2    Yap, G.S.3
  • 31
    • 2442706543 scopus 로고    scopus 로고
    • Massive number of antigenspecific CD4 T cells during vaccination with live attenuated Salmonella causes interclonal competition
    • Srinivasan, A., J. Foley, and S. J. McSorley. 2004. Massive number of antigenspecific CD4 T cells during vaccination with live attenuated Salmonella causes interclonal competition. J. Immunol. 172: 6884-6893.
    • (2004) J. Immunol. , vol.172 , pp. 6884-6893
    • Srinivasan, A.1    Foley, J.2    McSorley, S.J.3
  • 32
    • 76249117468 scopus 로고    scopus 로고
    • Tracking the total CD8 T cell response to infection reveals substantial discordance in magnitude and kinetics between inbred and outbred hosts
    • Rai, D., N. L. Pham, J. T. Harty, and V. P. Badovinac. 2009. Tracking the total CD8 T cell response to infection reveals substantial discordance in magnitude and kinetics between inbred and outbred hosts. J. Immunol. 183: 7672-7681.
    • (2009) J. Immunol. , vol.183 , pp. 7672-7681
    • Rai, D.1    Pham, N.L.2    Harty, J.T.3    Badovinac, V.P.4
  • 33
    • 82755186803 scopus 로고    scopus 로고
    • Quantifying antigen-specific CD4 T cells during a viral infection: CD4 T cell responses are larger than we think
    • McDermott, D. S., and S. M. Varga. 2011. Quantifying antigen-specific CD4 T cells during a viral infection: CD4 T cell responses are larger than we think. J. Immunol. 187: 5568-5576.
    • (2011) J. Immunol. , vol.187 , pp. 5568-5576
    • McDermott, D.S.1    Varga, S.M.2
  • 35
    • 84867591997 scopus 로고    scopus 로고
    • The Toxoplasma gondii peptide AS15 elicits CD4 T cells that can control parasite burden
    • Grover, H. S., N. Blanchard, F. Gonzalez, S. Chan, E. A. Robey, and N. Shastri. 2012. The Toxoplasma gondii peptide AS15 elicits CD4 T cells that can control parasite burden. Infect. Immun. 80: 3279-3288.
    • (2012) Infect. Immun. , vol.80 , pp. 3279-3288
    • Grover, H.S.1    Blanchard, N.2    Gonzalez, F.3    Chan, S.4    Robey, E.A.5    Shastri, N.6
  • 36
    • 77950433922 scopus 로고    scopus 로고
    • Differential regulation of effector- and central-memory responses to Toxoplasma gondii Infection by IL-12 revealed by tracking of Tgd057-specific CD8+ T cells
    • Wilson, D. C., G. M. Grotenbreg, K. Liu, Y. Zhao, E. M. Frickel, M. J. Gubbels, H. L. Ploegh, and G. S. Yap. 2010. Differential regulation of effector- and central-memory responses to Toxoplasma gondii Infection by IL-12 revealed by tracking of Tgd057-specific CD8+ T cells. PLoS Pathog. 6: e1000815.
    • (2010) PLoS Pathog. , vol.6
    • Wilson, D.C.1    Grotenbreg, G.M.2    Liu, K.3    Zhao, Y.4    Frickel, E.M.5    Gubbels, M.J.6    Ploegh, H.L.7    Yap, G.S.8
  • 38
    • 0023895411 scopus 로고
    • Interferon-gamma: The major mediator of resistance against Toxoplasma gondii
    • Suzuki, Y., M. A. Orellana, R. D. Schreiber, and J. S. Remington. 1988. Interferon-gamma: the major mediator of resistance against Toxoplasma gondii. Science 240: 516-518.
    • (1988) Science , vol.240 , pp. 516-518
    • Suzuki, Y.1    Orellana, M.A.2    Schreiber, R.D.3    Remington, J.S.4
  • 39
    • 0030294163 scopus 로고    scopus 로고
    • In the absence of endogenous IFN-gamma, mice develop unimpaired IL-12 responses to Toxoplasma gondii while failing to control acute infection
    • Scharton-Kersten, T. M., T. A. Wynn, E. Y. Denkers, S. Bala, E. Grunvald, S. Hieny, R. T. Gazzinelli, and A. Sher. 1996. In the absence of endogenous IFN-gamma, mice develop unimpaired IL-12 responses to Toxoplasma gondii while failing to control acute infection. J. Immunol. 157: 4045-4054.
    • (1996) J. Immunol. , vol.157 , pp. 4045-4054
    • Scharton-Kersten, T.M.1    Wynn, T.A.2    Denkers, E.Y.3    Bala, S.4    Grunvald, E.5    Hieny, S.6    Gazzinelli, R.T.7    Sher, A.8
  • 40
    • 0029959459 scopus 로고    scopus 로고
    • In the absence of endogenous IL-10, mice acutely infected with Toxoplasma gondii succumb to a lethal immune response dependent on CD4+ T cells and accompanied by overproduction of IL-12, IFN-gamma and TNF-alpha
    • Gazzinelli, R. T., M. Wysocka, S. Hieny, T. Scharton-Kersten, A. Cheever, R. Kühn, W. Müller, G. Trinchieri, and A. Sher. 1996. In the absence of endogenous IL-10, mice acutely infected with Toxoplasma gondii succumb to a lethal immune response dependent on CD4+ T cells and accompanied by overproduction of IL-12, IFN-gamma and TNF-alpha. J. Immunol. 157: 798-805.
    • (1996) J. Immunol. , vol.157 , pp. 798-805
    • Gazzinelli, R.T.1    Wysocka, M.2    Hieny, S.3    Scharton-Kersten, T.4    Cheever, A.5    Kühn, R.6    Müller, W.7    Trinchieri, G.8    Sher, A.9
  • 41
    • 0029841124 scopus 로고    scopus 로고
    • Association of CD4+ T cell-dependent, interferon-gamma-mediated necrosis of the small intestine with genetic susceptibility of mice to peroral infection with Toxoplasma gondii
    • Liesenfeld, O., J. Kosek, J. S. Remington, and Y. Suzuki. 1996. Association of CD4+ T cell-dependent, interferon-gamma-mediated necrosis of the small intestine with genetic susceptibility of mice to peroral infection with Toxoplasma gondii. J. Exp. Med. 184: 597-607.
    • (1996) J. Exp. Med. , vol.184 , pp. 597-607
    • Liesenfeld, O.1    Kosek, J.2    Remington, J.S.3    Suzuki, Y.4
  • 43
    • 84885462754 scopus 로고    scopus 로고
    • CD4+ T cells are trigger and target of the glucocorticoid response that prevents lethal immunopathology in toxoplasma infection
    • Kugler, D. G., P. R. Mittelstadt, J. D. Ashwell, A. Sher, and D. Jankovic. 2013. CD4+ T cells are trigger and target of the glucocorticoid response that prevents lethal immunopathology in toxoplasma infection. J. Exp. Med. 210: 1919-1927.
    • (2013) J. Exp. Med. , vol.210 , pp. 1919-1927
    • Kugler, D.G.1    Mittelstadt, P.R.2    Ashwell, J.D.3    Sher, A.4    Jankovic, D.5
  • 44
    • 0028272528 scopus 로고
    • Production of gamma interferon by natural killer cells from Toxoplasma gondii-infected SCID mice: Regulation by interleukin-10, interleukin-12, and tumor necrosis factor alpha
    • Hunter, C. A., C. S. Subauste, V. H. Van Cleave, and J. S. Remington. 1994. Production of gamma interferon by natural killer cells from Toxoplasma gondii-infected SCID mice: regulation by interleukin-10, interleukin-12, and tumor necrosis factor alpha. Infect. Immun. 62: 2818-2824.
    • (1994) Infect. Immun. , vol.62 , pp. 2818-2824
    • Hunter, C.A.1    Subauste, C.S.2    Van Cleave, V.H.3    Remington, J.S.4
  • 45
    • 1842417179 scopus 로고    scopus 로고
    • Role of interleukin-10 in regulation of T-cell-dependent and T-cell-independent mechanisms of resistance to Toxoplasma gondii
    • Neyer, L. E., G. Grunig, M. Fort, J. S. Remington, D. Rennick, and C. A. Hunter. 1997. Role of interleukin-10 in regulation of T-cell-dependent and T-cell-independent mechanisms of resistance to Toxoplasma gondii. Infect. Immun. 65: 1675-1682.
    • (1997) Infect. Immun. , vol.65 , pp. 1675-1682
    • Neyer, L.E.1    Grunig, G.2    Fort, M.3    Remington, J.S.4    Rennick, D.5    Hunter, C.A.6
  • 46
    • 33749263389 scopus 로고    scopus 로고
    • Organ- and disease-stage-specific regulation of Toxoplasma gondii-specific CD8-T-cell responses by CD4 T cells
    • Lütjen, S., S. Soltek, S. Virna, M. Deckert, and D. Schlüter. 2006. Organ- and disease-stage-specific regulation of Toxoplasma gondii-specific CD8-T-cell responses by CD4 T cells. Infect. Immun. 74: 5790-5801.
    • (2006) Infect. Immun. , vol.74 , pp. 5790-5801
    • Lütjen, S.1    Soltek, S.2    Virna, S.3    Deckert, M.4    Schlüter, D.5
  • 48
    • 0023232366 scopus 로고
    • Two types of mouse helper T-cell clone Implications for immune regulation
    • Mosmann, T. R., and R. L. Coffman. 1987. Two types of mouse helper T-cell clone Implications for immune regulation. Immunol. Today 8: 223-227.
    • (1987) Immunol. Today , vol.8 , pp. 223-227
    • Mosmann, T.R.1    Coffman, R.L.2
  • 49
    • 0027358451 scopus 로고
    • Gamma interferon-dependent temporary resistance to acute Toxoplasma gondii infection independent of CD4+ or CD8+ lymphocytes
    • Johnson, L. L., F. P. VanderVegt, and E. A. Havell. 1993. Gamma interferon-dependent temporary resistance to acute Toxoplasma gondii infection independent of CD4+ or CD8+ lymphocytes. Infect. Immun. 61: 5174-5180.
    • (1993) Infect. Immun. , vol.61 , pp. 5174-5180
    • Johnson, L.L.1    VanderVegt, F.P.2    Havell, E.A.3
  • 50
    • 0036155973 scopus 로고    scopus 로고
    • CD8(+)-T-cell immunity against Toxoplasma gondii can be induced but not maintained in mice lacking conventional CD4(+) T cells
    • Casciotti, L., K. H. Ely, M. E. Williams, and I. A. Khan. 2002. CD8(+)-T-cell immunity against Toxoplasma gondii can be induced but not maintained in mice lacking conventional CD4(+) T cells. Infect. Immun. 70: 434-443.
    • (2002) Infect. Immun. , vol.70 , pp. 434-443
    • Casciotti, L.1    Ely, K.H.2    Williams, M.E.3    Khan, I.A.4
  • 52
    • 0036628958 scopus 로고    scopus 로고
    • The role of cytokines and their signaling pathways in the regulation of immunity to Toxoplasma gondii
    • Lieberman, L. A., and C. A. Hunter. 2002. The role of cytokines and their signaling pathways in the regulation of immunity to Toxoplasma gondii. Int. Rev. Immunol. 21: 373-403.
    • (2002) Int. Rev. Immunol. , vol.21 , pp. 373-403
    • Lieberman, L.A.1    Hunter, C.A.2
  • 53
    • 12744273260 scopus 로고    scopus 로고
    • Natural killer cells and innate immunity to protozoan pathogens
    • Korbel, D. S., O. C. Finney, and E. M. Riley. 2004. Natural killer cells and innate immunity to protozoan pathogens. Int. J. Parasitol. 34: 1517-1528.
    • (2004) Int. J. Parasitol. , vol.34 , pp. 1517-1528
    • Korbel, D.S.1    Finney, O.C.2    Riley, E.M.3
  • 54
    • 33745401218 scopus 로고    scopus 로고
    • Natural killer cells as an initial defense against pathogens
    • Lodoen, M. B., and L. L. Lanier. 2006. Natural killer cells as an initial defense against pathogens. Curr. Opin. Immunol. 18: 391-398.
    • (2006) Curr. Opin. Immunol. , vol.18 , pp. 391-398
    • Lodoen, M.B.1    Lanier, L.L.2
  • 55
    • 65749103365 scopus 로고    scopus 로고
    • The transcription factor T-bet controls regulatory T cell homeostasis and function during type 1 inflammation
    • Koch, M. A., G. Tucker-Heard, N. R. Perdue, J. R. Killebrew, K. B. Urdahl, and D. J. Campbell. 2009. The transcription factor T-bet controls regulatory T cell homeostasis and function during type 1 inflammation. Nat. Immunol. 10: 595-602.
    • (2009) Nat. Immunol. , vol.10 , pp. 595-602
    • Koch, M.A.1    Tucker-Heard, G.2    Perdue, N.R.3    Killebrew, J.R.4    Urdahl, K.B.5    Campbell, D.J.6
  • 56
    • 0033710213 scopus 로고    scopus 로고
    • IP-10 is critical for effector T cell trafficking and host survival in Toxoplasma gondii infection
    • Khan, I. A., J. A. MacLean, F. S. Lee, L. Casciotti, E. DeHaan, J. D. Schwartzman, and A. D. Luster. 2000. IP-10 is critical for effector T cell trafficking and host survival in Toxoplasma gondii infection. Immunity 12: 483-494.
    • (2000) Immunity , vol.12 , pp. 483-494
    • Khan, I.A.1    MacLean, J.A.2    Lee, F.S.3    Casciotti, L.4    DeHaan, E.5    Schwartzman, J.D.6    Luster, A.D.7
  • 57
    • 59749094882 scopus 로고    scopus 로고
    • CXCR3-deficiency protects influenza-infected CCR5-deficient mice from mortality
    • Fadel, S. A., S. K. Bromley, B. D. Medoff, and A. D. Luster. 2008. CXCR3-deficiency protects influenza-infected CCR5-deficient mice from mortality. Eur. J. Immunol. 38: 3376-3387.
    • (2008) Eur. J. Immunol. , vol.38 , pp. 3376-3387
    • Fadel, S.A.1    Bromley, S.K.2    Medoff, B.D.3    Luster, A.D.4
  • 58
    • 51149099027 scopus 로고    scopus 로고
    • CXCL10/CXCR3-mediated responses promote immunity to respiratory syncytial virus infection by augmenting dendritic cell and CD8(+) T cell efficacy
    • Lindell, D. M., T. E. Lane, and N. W. Lukacs. 2008. CXCL10/CXCR3-mediated responses promote immunity to respiratory syncytial virus infection by augmenting dendritic cell and CD8(+) T cell efficacy. Eur. J. Immunol. 38: 2168-2179.
    • (2008) Eur. J. Immunol. , vol.38 , pp. 2168-2179
    • Lindell, D.M.1    Lane, T.E.2    Lukacs, N.W.3
  • 60
    • 0034071178 scopus 로고    scopus 로고
    • Blockade of costimulation prevents infection-induced immunopathology in interleukin-10-deficient mice
    • Villegas, E. N., U. Wille, L. Craig, P. S. Linsley, D. M. Rennick, R. Peach, and C. A. Hunter. 2000. Blockade of costimulation prevents infection-induced immunopathology in interleukin-10-deficient mice. Infect. Immun. 68: 2837-2844.
    • (2000) Infect. Immun. , vol.68 , pp. 2837-2844
    • Villegas, E.N.1    Wille, U.2    Craig, L.3    Linsley, P.S.4    Rennick, D.M.5    Peach, R.6    Hunter, C.A.7
  • 61
    • 0036892201 scopus 로고    scopus 로고
    • Contribution of interleukin-12 (IL-12) and the CD28/B7 and CD40/CD40 ligand pathways to the development of a pathological T-cell response in IL-10-deficient mice
    • Wille, U., E. N. Villegas, L. Craig, R. Peach, and C. A. Hunter. 2002. Contribution of interleukin-12 (IL-12) and the CD28/B7 and CD40/CD40 ligand pathways to the development of a pathological T-cell response in IL-10-deficient mice. Infect. Immun. 70: 6940-6947.
    • (2002) Infect. Immun. , vol.70 , pp. 6940-6947
    • Wille, U.1    Villegas, E.N.2    Craig, L.3    Peach, R.4    Hunter, C.A.5
  • 64
    • 33745699554 scopus 로고    scopus 로고
    • The T-box transcription factor T-bet in immunity and auto-immunity
    • Peng, S. L. 2006. The T-box transcription factor T-bet in immunity and auto-immunity. Cell. Mol. Immunol. 3: 87-95.
    • (2006) Cell. Mol. Immunol. , vol.3 , pp. 87-95
    • Peng, S.L.1
  • 67
    • 84878073297 scopus 로고    scopus 로고
    • Lysine 313 of T-box is crucial for modulation of protein stability, DNA binding, and threonine phosphorylation of T-bet
    • Jang, E. J., H. R. Park, J. H. Hong, and E. S. Hwang. 2013. Lysine 313 of T-box is crucial for modulation of protein stability, DNA binding, and threonine phosphorylation of T-bet. J. Immunol. 190: 5764-5770.
    • (2013) J. Immunol. , vol.190 , pp. 5764-5770
    • Jang, E.J.1    Park, H.R.2    Hong, J.H.3    Hwang, E.S.4
  • 68
    • 84875481910 scopus 로고    scopus 로고
    • CD11a regulates effector CD8 T cell differentiation and central memory development in response to infection with Listeria monocytogenes
    • Bose, T. O., Q. M. Pham, E. R. Jellison, J. Mouries, C. M. Ballantyne, and L. Lefrançois. 2013. CD11a regulates effector CD8 T cell differentiation and central memory development in response to infection with Listeria monocytogenes. Infect. Immun. 81: 1140-1151.
    • (2013) Infect. Immun. , vol.81 , pp. 1140-1151
    • Bose, T.O.1    Pham, Q.M.2    Jellison, E.R.3    Mouries, J.4    Ballantyne, C.M.5    Lefrançois, L.6
  • 69
    • 84875461917 scopus 로고    scopus 로고
    • Secondary T cell-T cell synaptic interactions drive the differentiation of protective CD8+ T cells
    • Gérard, A., O. Khan, P. Beemiller, E. Oswald, J. Hu, M. Matloubian, and M. F. Krummel. 2013. Secondary T cell-T cell synaptic interactions drive the differentiation of protective CD8+ T cells. Nat. Immunol. 14: 356-363.
    • (2013) Nat. Immunol. , vol.14 , pp. 356-363
    • Gérard, A.1    Khan, O.2    Beemiller, P.3    Oswald, E.4    Hu, J.5    Matloubian, M.6    Krummel, M.F.7


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