Adverse outcome pathways during early fish development: A conceptual framework for identification of chemical screening and prioritization strategies

Toxicological Sciences

Volumn 123, Issue 2, 2011, Pages 349-358

  Volz, David C ^a   Belanger, Scott ^b   Embry, Michelle ^c   Padilla, Stephanie ^d   Sanderson, Hans ^e   Schirmer, Kristin ^f   Scholz, Stefan ^g   Villeneuve, Daniel ^d  

^a UNIVERSITY OF SOUTH CAROLINA   (United States)

^b PROCTER AND GAMBLE COMPANY   (United States)

^c ILSI HEALTH AND ENVIRONMENTAL SCIENCES INSTITUTE   (United States)

^d U S ENVIRONMENTAL PROTECTION AGENCY   (United States)

^e AARHUS UNIVERSITY   (Denmark)

^f SWISS FEDERAL INSTITUTE OF AQUATIC SCIENCE AND TECHNOLOGY   (Switzerland)

^g HELMHOLTZ CENTRE FOR ENVIRONMENTAL RESEARCH UFZ   (Germany)

Author keywords

Adverse outcome pathway; Fish early life stage test; High throughput screening; Zebrafish embryo

Indexed keywords

2,3,7,8 TETRACHLORODIBENZO PARA DIOXIN; ALKYLBENZENESULFONIC ACID; CHLORPYRIFOS;

ADVERSE OUTCOME; ANESTHESIA; ARTICLE; BIOASSAY; CARDIOTOXICITY; CELL VIABILITY; CONCEPTUAL FRAMEWORK; ECOTOXICITY; FISH; FISH EARLY LIFE STAGE TEST; GILL; HIGH THROUGHPUT SCREENING; NERVE FIBER; NERVE FIBER GROWTH; NONHUMAN;

ALKANESULFONIC ACIDS; ANIMAL TESTING ALTERNATIVES; ANIMALS; CHLORPYRIFOS; ENVIRONMENTAL MONITORING; FISHES; HAZARDOUS SUBSTANCES; HEALTH PRIORITIES; HIGH-THROUGHPUT SCREENING ASSAYS; LIFE CYCLE STAGES; MASS SCREENING; RESEARCH DESIGN; RISK ASSESSMENT; TETRACHLORODIBENZODIOXIN; TOXICITY TESTS, CHRONIC;

ANIMALIA; DANIO RERIO;

EID: 80053461295     PISSN: 10966080     EISSN: 10960929     Source Type: Journal    
DOI: 10.1093/toxsci/kfr185     Document Type: Article

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