-
3
-
-
33847687731
-
Researching severe sepsis and organ dysfunction in children: A global perspective (resolve) study group: Drotrecogin alfa (activated) in children with severe sepsis: A multicentre phase iii randomised controlled trial
-
Nadel S, Goldstein B, Williams MD, et al; REsearching severe Sepsis and Organ dysfunction in children: A gLobal perspective (RESOLVE) study group: Drotrecogin alfa (activated) in children with severe sepsis: A multicentre phase III randomised controlled trial. Lancet 2007; 369:836-843
-
(2007)
Lancet
, vol.369
, pp. 836-843
-
-
Nadel, S.1
Goldstein, B.2
Williams, M.D.3
-
4
-
-
84864282573
-
Defning pediatric sepsis by different criteria: Discrepancies in populations and implications for clinical practice
-
Weiss SL, Parker B, Bullock ME, et al: Defning pediatric sepsis by different criteria: Discrepancies in populations and implications for clinical practice. Pediatr Crit Care Med 2012; 13:e219-e226
-
(2012)
Pediatr Crit Care Med
, vol.13
, pp. e219-e226
-
-
Weiss, S.L.1
Parker, B.2
Bullock, M.E.3
-
5
-
-
79953819133
-
Immunoparalysis and nosocomial infection in children with multiple organ dysfunction syndrome
-
Hall MW, Knatz NL, Vetterly C, et al: Immunoparalysis and nosocomial infection in children with multiple organ dysfunction syndrome. Intensive Care Med 2011; 37:525-532
-
(2011)
Intensive Care Med
, vol.37
, pp. 525-532
-
-
Hall, M.W.1
Knatz, N.L.2
Vetterly, C.3
-
6
-
-
10644281080
-
Mitochondrial dysfunction in septic shock and multiple organ dysfunction syndrome
-
Crouser ED: Mitochondrial dysfunction in septic shock and multiple organ dysfunction syndrome. Mitochondrion 2004; 4:729-741
-
(2004)
Mitochondrion
, vol.4
, pp. 729-741
-
-
Crouser, E.D.1
-
7
-
-
68049083727
-
Alterations of mitochondrial function in sepsis and critical illness
-
Harrois A, Huet O, Duranteau J: Alterations of mitochondrial function in sepsis and critical illness. Curr Opin Anaesthesiol 2009; 22:143-149
-
(2009)
Curr Opin Anaesthesiol
, vol.22
, pp. 143-149
-
-
Harrois, A.1
Huet, O.2
Duranteau, J.3
-
8
-
-
79953180902
-
Assessing mitochondrial dysfunction in cells
-
Brand MD, Nicholls DG: Assessing mitochondrial dysfunction in cells. Biochem J 2011; 435:297-312
-
(2011)
Biochem J
, vol.435
, pp. 297-312
-
-
Brand, M.D.1
Nicholls, D.G.2
-
9
-
-
82355161907
-
High-resolution respirometry: Oxphos protocols for human cells and permeabilized fbers form small biopsies of human muscle
-
Palmeira CM, Moreno AJ (Eds). New York Springer Science + Business Media 2012 25-58
-
Pesta D, Gaiger E: High-resolution respirometry: OXPHOS protocols for human cells and permeabilized fbers form small biopsies of human muscle. In: Mitochondrial Bioenergetics: Methods and Protocols. Palmeira CM, Moreno AJ (Eds). New York, Springer Science + Business Media, 2012, pp 25-58
-
Mitochondrial Bioenergetics: Methods and Protocols
-
-
Pesta, D.1
Gaiger, E.2
-
10
-
-
65649092131
-
Bioenergetic analysis of isolated cerebrocortical nerve terminals on a microgram scale: Spare respiratory capacity and stochastic mitochondrial failure
-
Choi SW, Gerencser AA, Nicholls DG: Bioenergetic analysis of isolated cerebrocortical nerve terminals on a microgram scale: Spare respiratory capacity and stochastic mitochondrial failure. J Neurochem 2009; 109:1179-1191
-
(2009)
J Neurochem
, vol.109
, pp. 1179-1191
-
-
Choi, S.W.1
Gerencser, A.A.2
Nicholls, D.G.3
-
11
-
-
84856183120
-
Mitochondrial respiratory capacity is a critical regulator of cd8+ t cell memory development
-
van der Windt GJ, Everts B, Chang CH, et al: Mitochondrial respiratory capacity is a critical regulator of CD8+ T cell memory development. Immunity 2012; 36:68-78
-
(2012)
Immunity
, vol.36
, pp. 68-78
-
-
Van Der Windt, G.J.1
Everts, B.2
Chang, C.H.3
-
12
-
-
4644282833
-
Competitive and noncompetitive inhibition of myocardial cytochrome c oxidase in sepsis
-
Levy RJ, Vijayasarathy C, Raj NR, et al: Competitive and noncompetitive inhibition of myocardial cytochrome C oxidase in sepsis. Shock 2004; 21:110-114
-
(2004)
Shock
, vol.21
, pp. 110-114
-
-
Levy, R.J.1
Vijayasarathy, C.2
Raj, N.R.3
-
13
-
-
34447104809
-
Suppression of mitochondrial atpase inhibitor protein (if1) in the liver of late septic rats
-
Huang LJ, Hsu C, Tsai TN, et al: Suppression of mitochondrial ATPase inhibitor protein (IF1) in the liver of late septic rats. Biochim Biophys Acta 2007; 1767:888-896
-
(2007)
Biochim Biophys Acta
, vol.1767
, pp. 888-896
-
-
Huang, L.J.1
Hsu, C.2
Tsai, T.N.3
-
14
-
-
0019932028
-
Alterations of mitochondrial metabolism and protein concentrations in subacute septicemia
-
Tavakoli H, Mela L: Alterations of mitochondrial metabolism and protein concentrations in subacute septicemia. Infect Immun 1982; 38:536-541
-
(1982)
Infect Immun
, vol.38
, pp. 536-541
-
-
Tavakoli, H.1
Mela, L.2
-
15
-
-
0037142987
-
Association between mitochondrial dysfunction and severity and outcome of septic shock
-
Brealey D, Brand M, Hargreaves I, et al: Association between mitochondrial dysfunction and severity and outcome of septic shock. Lancet 2002; 360:219-223
-
(2002)
Lancet
, vol.360
, pp. 219-223
-
-
Brealey, D.1
Brand, M.2
Hargreaves, I.3
-
16
-
-
33751186701
-
Derangements in mitochondrial metabolism in intercostal and leg muscle of critically ill patients with sepsis-induced multiple organ failure
-
Fredriksson K, Hammarqvist F, Strigård K, et al: Derangements in mitochondrial metabolism in intercostal and leg muscle of critically ill patients with sepsis-induced multiple organ failure. Am J Physiol Endocrinol Metab 2006; 291:E1044-E1050
-
(2006)
Am J Physiol Endocrinol Metab
, vol.291
, pp. E1044-E1050
-
-
Fredriksson, K.1
Hammarqvist, F.2
Strigård, K.3
-
17
-
-
0035422607
-
Mitochondrial membrane potential and apoptosis peripheral blood monocytes in severe human sepsis
-
Adrie C, Bachelet M, Vayssier-Taussat M, et al: Mitochondrial membrane potential and apoptosis peripheral blood monocytes in severe human sepsis. Am J Respir Crit Care Med 2001; 164:389-395
-
(2001)
Am J Respir Crit Care Med
, vol.164
, pp. 389-395
-
-
Adrie, C.1
Bachelet, M.2
Vayssier-Taussat, M.3
-
18
-
-
36448993710
-
Oxygen consumption of human peripheral blood mononuclear cells in severe human sepsis
-
Belikova I, Lukaszewicz AC, Faivre V, et al: Oxygen consumption of human peripheral blood mononuclear cells in severe human sepsis. Crit Care Med 2007; 35:2702-2708
-
(2007)
Crit Care Med
, vol.35
, pp. 2702-2708
-
-
Belikova, I.1
Lukaszewicz, A.C.2
Faivre, V.3
-
19
-
-
84855892492
-
The effects of sepsis on mitochondria
-
Garrabou G, Morén C, López S, et al: The effects of sepsis on mitochondria. J Infect Dis 2012; 205:392-400
-
(2012)
J Infect Dis
, vol.205
, pp. 392-400
-
-
Garrabou, G.1
Morén, C.2
López, S.3
-
20
-
-
79955476448
-
Bioenergetic failure of human peripheral blood monocytes in patients with septic shock is mediated by reduced f1fo adenosine-5'-Triphosphate synthase activity
-
Japiassú AM, Santiago AP, dAvila JC, et al: Bioenergetic failure of human peripheral blood monocytes in patients with septic shock is mediated by reduced F1Fo adenosine-5'-Triphosphate synthase activity. Crit Care Med 2011; 39:1056-1063
-
(2011)
Crit Care Med
, vol.39
, pp. 1056-1063
-
-
Japiassú, A.M.1
Santiago, A.P.2
Davila, J.C.3
-
21
-
-
84880955082
-
Patients with sepsis exhibit increased mitochondrial respiratory capacity in peripheral blood immune cells
-
Sjövall F, Morota S, Persson J, et al: Patients with sepsis exhibit increased mitochondrial respiratory capacity in peripheral blood immune cells. Crit Care 2013; 17:R152
-
(2013)
Crit Care
, vol.17
, pp. R152
-
-
Sjövall, F.1
Morota, S.2
Persson, J.3
-
22
-
-
84893196785
-
A review of the mitochondrial and glycolytic metabolism in human platelets and leukocytes: Implications for their use as bioenergetic biomarkers
-
Kramer PA, Ravi S, Chacko B, et al: A review of the mitochondrial and glycolytic metabolism in human platelets and leukocytes: Implications for their use as bioenergetic biomarkers. Redox Biol 2014; 2:206-210
-
(2014)
Redox Biol
, vol.2
, pp. 206-210
-
-
Kramer, P.A.1
Ravi, S.2
Chacko, B.3
-
23
-
-
84876758617
-
Metabolic pathways in immune cell activation and quiescence
-
Pearce EL, Pearce EJ: Metabolic pathways in immune cell activation and quiescence. Immunity 2013; 38:633-643
-
(2013)
Immunity
, vol.38
, pp. 633-643
-
-
Pearce, E.L.1
Pearce, E.J.2
-
24
-
-
84865285455
-
Metabolic switching and fuel choice during t-cell differentiation and memory development
-
van der Windt GJ, Pearce EL: Metabolic switching and fuel choice during T-cell differentiation and memory development. Immunol Rev 2012; 249:27-42
-
(2012)
Immunol Rev
, vol.249
, pp. 27-42
-
-
Van Der Windt, G.J.1
Pearce, E.L.2
-
25
-
-
84905116272
-
The bioenergetic health index: A new concept in mitochondrial translational research
-
Chacko BK, Kramer PA, Ravi S, et al: The Bioenergetic Health Index: A new concept in mitochondrial translational research. Clin Sci (Lond) 2014; 127:367-373
-
(2014)
Clin Sci (Lond
, vol.127
, pp. 367-373
-
-
Chacko, B.K.1
Kramer, P.A.2
Ravi, S.3
-
26
-
-
84880264094
-
Hemorrhagic shock and resuscitation are associated with peripheral blood mononuclear cell mitochondrial dysfunction and immunosuppression
-
Villarroel JP, Guan Y, Werlin E, et al: Hemorrhagic shock and resuscitation are associated with peripheral blood mononuclear cell mitochondrial dysfunction and immunosuppression. J Trauma Acute Care Surg 2013; 75:24-31
-
(2013)
J Trauma Acute Care Surg
, vol.75
, pp. 24-31
-
-
Villarroel, J.P.1
Guan, Y.2
Werlin, E.3
-
27
-
-
84888137753
-
Can peripheral blood mononuclear cells be used as a proxy for mitochondrial dysfunction in vital organs during hemorrhagic shock and resuscitation?
-
Karamercan MA, Weiss SL, Villarroel JP, et al: Can peripheral blood mononuclear cells be used as a proxy for mitochondrial dysfunction in vital organs during hemorrhagic shock and resuscitation? Shock 2013; 40:476-484
-
(2013)
Shock
, vol.40
, pp. 476-484
-
-
Karamercan, M.A.1
Weiss, S.L.2
Villarroel, J.P.3
-
28
-
-
80053459442
-
Differences between adult and pediatric septic shock
-
Aneja R, Carcillo J: Differences between adult and pediatric septic shock. Minerva Anestesiol 2011; 77:986-992
-
(2011)
Minerva Anestesiol
, vol.77
, pp. 986-992
-
-
Aneja, R.1
Carcillo, J.2
-
29
-
-
0036830474
-
Mitochondrial function and dysfunction in the cell: Its relevance to aging and aging-related disease
-
Nicholls DG: Mitochondrial function and dysfunction in the cell: Its relevance to aging and aging-related disease. Int J Biochem Cell Biol 2002; 34:1372-1381
-
(2002)
Int J Biochem Cell Biol
, vol.34
, pp. 1372-1381
-
-
Nicholls, D.G.1
-
30
-
-
21644438082
-
International consensus conference on pediatric sepsis: International pediatric sepsis consensus conference: Defnitions for sepsis and organ dysfunction in pediatrics
-
Goldstein B, Giroir B, Randolph A; International Consensus Conference on Pediatric Sepsis: International pediatric sepsis consensus conference: Defnitions for sepsis and organ dysfunction in pediatrics. Pediatr Crit Care Med 2005; 6:2-8
-
(2005)
Pediatr Crit Care Med
, vol.6
, pp. 2-8
-
-
Goldstein, B.1
Giroir, B.2
Randolph, A.3
-
31
-
-
0028223811
-
Timing and predictors of death in pediatric patients with multiple organ system failure
-
Proulx F, Gauthier M, Nadeau D, et al: Timing and predictors of death in pediatric patients with multiple organ system failure. Crit Care Med 1994; 22:1025-1031
-
(1994)
Crit Care Med
, vol.22
, pp. 1025-1031
-
-
Proulx, F.1
Gauthier, M.2
Nadeau, D.3
-
32
-
-
0029931329
-
Prism iii: An updated pediatric risk of mortality score
-
Pollack MM, Patel KM, Ruttimann UE: PRISM III: An updated Pediatric Risk of Mortality score. Crit Care Med 1996; 24:743-752
-
(1996)
Crit Care Med
, vol.24
, pp. 743-752
-
-
Pollack, M.M.1
Patel, K.M.2
Ruttimann, U.E.3
-
33
-
-
0038783334
-
Validation of the paediat-ric logistic organ dysfunction (pelod) score: Prospective, observational, multicentre study
-
Leteurtre S, Martinot A, Duhamel A, et al: Validation of the paediat-ric logistic organ dysfunction (PELOD) score: Prospective, observational, multicentre study. Lancet 2003; 362:192-197
-
(2003)
Lancet
, vol.362
, pp. 192-197
-
-
Leteurtre, S.1
Martinot, A.2
Duhamel, A.3
-
34
-
-
77949458090
-
Vasoactive-inotropic score as a predictor of morbidity and mortality in infants after cardiopulmonary bypass
-
Gaies MG, Gurney JG, Yen AH, et al: Vasoactive-inotropic score as a predictor of morbidity and mortality in infants after cardiopulmonary bypass. Pediatr Crit Care Med 2010; 11:234-238
-
(2010)
Pediatr Crit Care Med
, vol.11
, pp. 234-238
-
-
Gaies, M.G.1
Gurney, J.G.2
Yen, A.H.3
-
35
-
-
5444224643
-
Effcacy of mitotracker green and cmxrosamine to measure changes in mitochondrial membrane potentials in living cells and tissues
-
Pendergrass W, Wolf N, Poot M: Effcacy of MitoTracker Green and CMXrosamine to measure changes in mitochondrial membrane potentials in living cells and tissues. Cytometry A 2004; 61:162-169
-
(2004)
Cytometry A
, vol.61
, pp. 162-169
-
-
Pendergrass, W.1
Wolf, N.2
Poot, M.3
-
36
-
-
34249781383
-
Mild uncoupling' does not decrease mitochondrial superoxide levels in cultured cerebellar granule neurons but decreases spare respiratory capacity and increases toxicity to glutamate and oxidative stress
-
Johnson-Cadwell LI, Jekabsons MB, Wang A, et al: 'Mild Uncoupling' does not decrease mitochondrial superoxide levels in cultured cerebellar granule neurons but decreases spare respiratory capacity and increases toxicity to glutamate and oxidative stress. J Neurochem 2007; 101:1619-1631
-
(2007)
J Neurochem
, vol.101
, pp. 1619-1631
-
-
Johnson-Cadwell, L.I.1
Jekabsons, M.B.2
Wang, A.3
-
37
-
-
78549296744
-
Temporal increase of platelet mitochondrial respiration is negatively associated with clinical outcome in patients with sepsis
-
Sjövall F, Morota S, Hansson MJ, et al: Temporal increase of platelet mitochondrial respiration is negatively associated with clinical outcome in patients with sepsis. Crit Care 2010; 14:R214
-
(2010)
Crit Care
, vol.14
, pp. R214
-
-
Sjövall, F.1
Morota, S.2
Hansson, M.J.3
-
38
-
-
84894464124
-
Relation of mitochondrial oxygen consumption in peripheral blood mononuclear cells to vascular function in type 2 diabetes mellitus
-
Hartman ML, Shirihai OS, Holbrook M, et al: Relation of mitochondrial oxygen consumption in peripheral blood mononuclear cells to vascular function in type 2 diabetes mellitus. Vasc Med 2014; 19:67-74
-
(2014)
Vasc Med
, vol.19
, pp. 67-74
-
-
Hartman, M.L.1
Shirihai, O.S.2
Holbrook, M.3
-
39
-
-
0034161442
-
Staining of mitochondrial membranes with 10-nonyl acridine orange mitofluor green, and mitotracker green is affected by mitochondrial membrane potential altering drugs
-
Keij JF, Bell-Prince C, Steinkamp JA: Staining of mitochondrial membranes with 10-nonyl acridine orange, MitoFluor Green, and MitoTracker Green is affected by mitochondrial membrane potential altering drugs. Cytometry 2000; 39:203-210
-
(2000)
Cytometry
, vol.39
, pp. 203-210
-
-
Keij, J.F.1
Bell-Prince, C.2
Steinkamp, J.A.3
-
40
-
-
84872066457
-
Insuffcient autophagy contributes to mitochondrial dysfunction, organ failure, and adverse outcome in an animal model of critical illness
-
Gunst J, Derese I, Aertgeerts A, et al: Insuffcient autophagy contributes to mitochondrial dysfunction, organ failure, and adverse outcome in an animal model of critical illness. Crit Care Med 2013; 41:182-194
-
(2013)
Crit Care Med
, vol.41
, pp. 182-194
-
-
Gunst, J.1
Derese, I.2
Aertgeerts, A.3
|